IL162143A0 - Pharmaceutical compositions comprising metformine and glibenclamide for treatment of type-II diabetes mellitus - Google Patents

Pharmaceutical compositions comprising metformine and glibenclamide for treatment of type-II diabetes mellitus

Info

Publication number
IL162143A0
IL162143A0 IL16214302A IL16214302A IL162143A0 IL 162143 A0 IL162143 A0 IL 162143A0 IL 16214302 A IL16214302 A IL 16214302A IL 16214302 A IL16214302 A IL 16214302A IL 162143 A0 IL162143 A0 IL 162143A0
Authority
IL
Israel
Prior art keywords
metformine
glibenclamide
treatment
type
pharmaceutical compositions
Prior art date
Application number
IL16214302A
Other languages
English (en)
Original Assignee
Menarini Int Operations Lu Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11442301&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL162143(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Menarini Int Operations Lu Sa filed Critical Menarini Int Operations Lu Sa
Publication of IL162143A0 publication Critical patent/IL162143A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL16214302A 2001-11-29 2002-11-29 Pharmaceutical compositions comprising metformine and glibenclamide for treatment of type-II diabetes mellitus IL162143A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2001FI000230A ITFI20010230A1 (it) 2001-11-29 2001-11-29 Composizioni farmaceutiche per il trattamento del diabete mellito di tipo ii
PCT/EP2002/013497 WO2003045355A1 (en) 2001-11-29 2002-11-29 Pharmaceutical compositions comprising metformine and glibenclamide for the treatment of type-ii diabetes mellitus

Publications (1)

Publication Number Publication Date
IL162143A0 true IL162143A0 (en) 2005-11-20

Family

ID=11442301

Family Applications (1)

Application Number Title Priority Date Filing Date
IL16214302A IL162143A0 (en) 2001-11-29 2002-11-29 Pharmaceutical compositions comprising metformine and glibenclamide for treatment of type-II diabetes mellitus

Country Status (39)

Country Link
US (1) US20050053661A1 (pl)
EP (1) EP1458364B1 (pl)
JP (1) JP4474162B2 (pl)
KR (1) KR20040079898A (pl)
CN (1) CN1596103B (pl)
AR (1) AR037407A1 (pl)
AT (1) ATE387190T1 (pl)
AU (1) AU2002358061B2 (pl)
BR (1) BR0214403A (pl)
CA (1) CA2466677A1 (pl)
CO (1) CO5590906A2 (pl)
CY (1) CY1107966T1 (pl)
DE (1) DE60225331T2 (pl)
DK (1) DK1458364T3 (pl)
EA (1) EA006766B1 (pl)
EG (1) EG24124A (pl)
ES (1) ES2302862T3 (pl)
HN (1) HN2002000341A (pl)
HR (1) HRP20040501A2 (pl)
HU (1) HUP0402154A3 (pl)
IL (1) IL162143A0 (pl)
IT (1) ITFI20010230A1 (pl)
MA (1) MA27087A1 (pl)
MX (1) MXPA04004974A (pl)
MY (1) MY141243A (pl)
NO (1) NO20042713L (pl)
NZ (1) NZ533779A (pl)
PA (1) PA8559801A1 (pl)
PE (1) PE20030580A1 (pl)
PL (1) PL206016B1 (pl)
PT (1) PT1458364E (pl)
RS (1) RS50937B (pl)
SI (1) SI1458364T1 (pl)
SV (1) SV2004001415A (pl)
TN (1) TNSN04095A1 (pl)
UA (1) UA81615C2 (pl)
UY (1) UY27549A1 (pl)
WO (1) WO2003045355A1 (pl)
ZA (1) ZA200404880B (pl)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE508738T1 (de) * 2001-01-12 2011-05-15 Sun Pharma Advanced Res Co Ltd System zur beabstandeten abgabe von arzneimitteln
WO2003105809A1 (en) 2002-06-17 2003-12-24 Themis Laboratories Private Limited Multilayer tablets containing thiazolidinedione and biguanides and methods for producing them
US9060941B2 (en) 2002-09-20 2015-06-23 Actavis, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US7785627B2 (en) 2002-09-20 2010-08-31 Watson Pharmaceuticals, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
EP1617832B1 (en) 2003-04-29 2008-03-12 Orexigen Therapeutics, Inc. Compositions for affecting weight loss
PE20061245A1 (es) * 2005-03-30 2007-01-06 Generex Pharm Inc Composiciones para la transmision transmucosa oral de la metformina
TWI471145B (zh) * 2005-06-13 2015-02-01 Bristol Myers Squibb & Gilead Sciences Llc 單一式藥學劑量型
DK2089005T3 (da) * 2006-11-09 2010-07-19 Orexigen Therapeutics Inc Lagdelte farmaceutiske formuleringer omfattende et hurtigt opløsende mellemlag
ITMI20062254A1 (it) * 2006-11-24 2008-05-25 Acraf Uso di un acido metossi-alcanoico dell'indazolo per preparare una composizione farmaceutca
WO2009158114A1 (en) 2008-05-30 2009-12-30 Orexigen Therapeutics, Inc. Methods for treating visceral fat conditions
CA2638240C (en) 2008-08-29 2010-02-02 Alexander Macgregor Method of treating dysglycemia and glucose excursions
RU2398572C1 (ru) * 2009-05-18 2010-09-10 Государственное образовательное учреждение высшего профессионального образования "Санкт-Петербургская государственная медицинская академия им. И.И. Мечникова Федерального агентства по здравоохранению и социальному развитию" Способ лечения больных сахарным диабетом 2 типа
MX344303B (es) 2010-01-11 2016-12-13 Orexigen Therapeutics Inc Metodos para proveer terapia de perdida de peso en pacientes con depresion mayor.
RU2483717C2 (ru) * 2010-11-22 2013-06-10 Открытое акционерное общество "Химико-фармацевтический комбинат "АКРИХИН" (ОАО "АКРИХИН") Фармацевтическая композиция для лечения диабета (варианты)
US9572784B2 (en) 2011-01-07 2017-02-21 Elcelyx Therapeutics, Inc. Compositions comprising statins, biguanides and further agents for reducing cardiometabolic risk
US11759441B2 (en) 2011-01-07 2023-09-19 Anji Pharmaceuticals Inc. Biguanide compositions and methods of treating metabolic disorders
US9211263B2 (en) 2012-01-06 2015-12-15 Elcelyx Therapeutics, Inc. Compositions and methods of treating metabolic disorders
US8796338B2 (en) 2011-01-07 2014-08-05 Elcelyx Therapeutics, Inc Biguanide compositions and methods of treating metabolic disorders
US9480663B2 (en) 2011-01-07 2016-11-01 Elcelyx Therapeutics, Inc. Biguanide compositions and methods of treating metabolic disorders
HUE051738T2 (hu) 2011-01-07 2021-03-29 Anji Pharma Us Llc Kemoszenzoros receptorligandum-alapú terápiák
US11974971B2 (en) 2011-01-07 2024-05-07 Anji Pharmaceuticals Inc. Compositions and methods for treating metabolic disorders
EA033067B1 (ru) 2012-01-06 2019-08-30 Элселикс Терапьютикс, Инк. Способ лечения метаболических расстройств у пациента, имеющего противопоказание к назначению бигуанидного соединения
KR20200137035A (ko) 2012-01-06 2020-12-08 앤지 파마 유에스 엘엘씨 바이구아나이드 조성물 및 대사 장애를 치료하는 방법
CN110893181A (zh) 2012-06-06 2020-03-20 纳丙药业有限责任公司 治疗超重和肥胖症的方法
BR112017009521A2 (pt) 2014-11-11 2017-12-19 Shionogi & Co comprimido de múltiplas camadas que contém um fármaco instável à luz
KR101750690B1 (ko) * 2015-10-28 2017-06-27 주식회사 종근당 메트포르민 및 로베글리타존을 포함하는 약제학적 조성물
CN105596339A (zh) * 2015-12-23 2016-05-25 青岛海之源智能技术有限公司 一种二甲双胍阿昔莫司复方组合物及制备方法
SG11202011883RA (en) 2018-05-31 2020-12-30 Hua Medicine Shanghai Ltd Pharmaceutical combination, composition, and combination formulation containing glucokinase activator and ppar receptor activator, and preparation methods and uses thereof
CN110128305A (zh) * 2019-05-10 2019-08-16 天津大学 二甲双胍-甲苯磺丁脲新盐型、其制备方法及医药用途
JP2021120357A (ja) * 2020-01-30 2021-08-19 サンノーバ株式会社 錠剤
GB2599950A (en) * 2020-10-16 2022-04-20 Zentiva Ks Pharmaceutical compositions with low amounts of nitrosamine impurities and methods for producing the same
CN113143940A (zh) * 2020-12-30 2021-07-23 成都恒瑞制药有限公司 一种抗糖尿病药物组合物的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2347531A1 (de) * 1973-09-21 1975-04-30 Hoechst Ag Arzneizubereitungen zur oralen diabetes-behandlung
IT1276130B1 (it) * 1995-11-14 1997-10-27 Gentili Ist Spa Associazione glibenclamide-metformina, composizioni farmaceutiche che la contengono e loro uso nel trattamento del diabete mellito di tipo
EP1063973B1 (en) * 1998-03-19 2016-11-16 Bristol-Myers Squibb Company Biphasic controlled release delivery system for high solubility pharmaceuticals and method
ATE250418T1 (de) * 1998-07-15 2003-10-15 Merck Sante Sas Tabletten enthaltend eine kombination von glibenclamid und metformin
US6780432B1 (en) * 2000-05-01 2004-08-24 Aeropharm Technology, Inc. Core formulation
ATE508738T1 (de) * 2001-01-12 2011-05-15 Sun Pharma Advanced Res Co Ltd System zur beabstandeten abgabe von arzneimitteln

Also Published As

Publication number Publication date
EP1458364B1 (en) 2008-02-27
UY27549A1 (es) 2003-06-30
SV2004001415A (es) 2004-05-07
NO20042713L (no) 2004-07-16
DK1458364T3 (da) 2008-06-23
DE60225331D1 (de) 2008-04-10
CO5590906A2 (es) 2005-12-30
MY141243A (en) 2010-03-31
EP1458364A1 (en) 2004-09-22
EA200400664A1 (ru) 2004-10-28
ITFI20010230A1 (it) 2003-05-29
RS50937B (sr) 2010-08-31
HN2002000341A (es) 2009-12-07
RS47304A (sr) 2006-10-27
NZ533779A (en) 2007-02-23
AR037407A1 (es) 2004-11-10
HRP20040501A2 (en) 2004-12-31
PE20030580A1 (es) 2003-09-05
UA81615C2 (ru) 2008-01-25
ZA200404880B (en) 2005-07-29
JP4474162B2 (ja) 2010-06-02
HUP0402154A3 (en) 2008-04-28
AU2002358061B2 (en) 2007-01-11
PT1458364E (pt) 2008-05-26
KR20040079898A (ko) 2004-09-16
US20050053661A1 (en) 2005-03-10
AU2002358061A1 (en) 2003-06-10
ATE387190T1 (de) 2008-03-15
HK1069974A1 (en) 2005-06-10
MXPA04004974A (es) 2004-08-11
TNSN04095A1 (en) 2006-06-01
DE60225331T2 (de) 2009-02-26
BR0214403A (pt) 2004-10-19
PL206016B1 (pl) 2010-06-30
PL369851A1 (pl) 2005-05-02
MA27087A1 (fr) 2004-12-20
ES2302862T3 (es) 2008-08-01
WO2003045355A1 (en) 2003-06-05
CN1596103A (zh) 2005-03-16
EA006766B1 (ru) 2006-04-28
CA2466677A1 (en) 2003-06-05
JP2005518360A (ja) 2005-06-23
CN1596103B (zh) 2010-06-16
CY1107966T1 (el) 2013-09-04
HUP0402154A2 (hu) 2005-02-28
SI1458364T1 (sl) 2008-08-31
EG24124A (en) 2008-07-07
PA8559801A1 (es) 2003-06-30

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees