IL162239A0 - Liquid composition of factor vii polypeptides - Google Patents
Liquid composition of factor vii polypeptidesInfo
- Publication number
- IL162239A0 IL162239A0 IL16223902A IL16223902A IL162239A0 IL 162239 A0 IL162239 A0 IL 162239A0 IL 16223902 A IL16223902 A IL 16223902A IL 16223902 A IL16223902 A IL 16223902A IL 162239 A0 IL162239 A0 IL 162239A0
- Authority
- IL
- Israel
- Prior art keywords
- factor vii
- liquid composition
- vii polypeptides
- iii
- polypeptides
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 229940012413 factor vii Drugs 0.000 title abstract 2
- 239000007788 liquid Substances 0.000 title abstract 2
- 229920001184 polypeptide Polymers 0.000 title abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 102100023804 Coagulation factor VII Human genes 0.000 abstract 1
- 108010023321 Factor VII Proteins 0.000 abstract 1
- 159000000007 calcium salts Chemical class 0.000 abstract 1
- 159000000003 magnesium salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Inorganic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200101948 | 2001-12-21 | ||
| US34688802P | 2002-01-07 | 2002-01-07 | |
| PCT/DK2002/000895 WO2003055512A1 (fr) | 2001-12-21 | 2002-12-20 | Composition liquide de polypeptides de facteur vii |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL162239A0 true IL162239A0 (en) | 2005-11-20 |
Family
ID=26069118
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL16223902A IL162239A0 (en) | 2001-12-21 | 2002-12-20 | Liquid composition of factor vii polypeptides |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US8022031B2 (fr) |
| EP (1) | EP1458408B1 (fr) |
| JP (1) | JP2005530683A (fr) |
| CN (1) | CN1607958A (fr) |
| AT (1) | ATE428439T1 (fr) |
| AU (1) | AU2002351756A1 (fr) |
| BR (1) | BR0215216A (fr) |
| CA (1) | CA2470511C (fr) |
| DE (1) | DE60232017D1 (fr) |
| ES (1) | ES2325653T3 (fr) |
| HU (1) | HUP0402315A3 (fr) |
| IL (1) | IL162239A0 (fr) |
| PL (1) | PL370652A1 (fr) |
| RU (1) | RU2357751C2 (fr) |
| WO (1) | WO2003055512A1 (fr) |
Families Citing this family (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7247708B2 (en) | 1997-10-23 | 2007-07-24 | Regents Of The University Of Minnesota | Modified vitamin K-dependent polypeptides |
| US6747003B1 (en) | 1997-10-23 | 2004-06-08 | Regents Of The University Of Minnesota | Modified vitamin K-dependent polypeptides |
| US7220837B1 (en) | 2000-04-28 | 2007-05-22 | Regents Of The University Of Minnesota | Modified vitamin K-dependent polypeptides |
| US7812132B2 (en) | 2000-04-28 | 2010-10-12 | Regents Of The University Of Minnesota | Modified vitamin K-dependent polypeptides |
| US20030211094A1 (en) | 2001-06-26 | 2003-11-13 | Nelsestuen Gary L. | High molecular weight derivatives of vitamin k-dependent polypeptides |
| KR20040065278A (ko) * | 2001-12-21 | 2004-07-21 | 노보 노르디스크 에이/에스 | 변경된 인자 ⅶ 폴리펩티드의 액체 조성물 |
| AU2002351756A1 (en) | 2001-12-21 | 2003-07-15 | Novo Nordisk Health Care Ag | Liquid composition of factor vii polypeptides |
| SI1499719T1 (sl) | 2002-04-30 | 2011-03-31 | Bayer Healthcare Llc | Polipeptidne variante faktorja VII ali VIIa |
| US20040009918A1 (en) * | 2002-05-03 | 2004-01-15 | Hanne Nedergaard | Stabilised solid compositions of modified factor VII |
| PT1517698E (pt) * | 2002-06-21 | 2014-11-19 | Novo Nordisk Healthcare Ag | Composições sólidas estabilizadas de polipéptidos do fator viia |
| AU2003266931B2 (en) | 2002-09-30 | 2010-01-21 | Bayer Healthcare Llc | FVII or FVIIa variants having increased clotting activity |
| RU2005132164A (ru) * | 2003-03-18 | 2006-06-10 | Ново Нордиск Хелт Кэр Аг (Ch) | Жидкие, водные фармацевтические композиции полипептидов фактора vii |
| DK1608745T3 (da) | 2003-03-20 | 2009-06-15 | Bayer Healthcare Llc | FVII eller FVIIa-Varianter |
| US7897734B2 (en) * | 2003-03-26 | 2011-03-01 | Novo Nordisk Healthcare Ag | Method for the production of proteins |
| KR20060015574A (ko) | 2003-05-23 | 2006-02-17 | 노보 노르디스크 헬스 케어 악티엔게젤샤프트 | 용액 중 단백질 안정화 |
| NZ573412A (en) | 2003-06-19 | 2010-09-30 | Maxygen Holdings Ltd | Factor VII or VIIa Gla domain variants |
| WO2004112828A1 (fr) | 2003-06-25 | 2004-12-29 | Novo Nordisk Health Care Ag | Composition liquide de polypeptides du facteur vii |
| EP1644030B1 (fr) * | 2003-07-01 | 2009-10-28 | Novo Nordisk Health Care AG | Preparations pharmaceutiques aqueuses liquides de polypeptides facteur vii |
| ES2574581T3 (es) * | 2003-08-14 | 2016-06-20 | Novo Nordisk Health Care Ag | Composición farmacéutica líquida acuosa de polipéptidos de tipo Factor VII |
| WO2005023308A1 (fr) * | 2003-09-05 | 2005-03-17 | Maxygen Holdings Ltd. | Formulations de polypeptides dependant de la vitamine k et sulfoalkyl ether cyclodextrines |
| RU2373953C2 (ru) * | 2003-12-19 | 2009-11-27 | Ново Нордиск Хелс Кеа Аг | Стабилизированная композиция, содержащая полипептид фактора vii |
| PL2708225T3 (pl) | 2004-04-23 | 2019-07-31 | Cydex Pharmaceuticals, Inc. | Formulacja DPI zawierająca eter sulfoalkilowy cyklodekstryny |
| ES2339953T5 (es) | 2004-05-04 | 2020-05-06 | Novo Nordisk Healthcare Ag | Glicoformas de factor VII ligadas a O y método de fabricación |
| US7148067B2 (en) * | 2004-08-31 | 2006-12-12 | The Board Of Trustees Of The University Of Illinois | Thromboplastin reagents |
| JP2006137678A (ja) * | 2004-11-10 | 2006-06-01 | Shionogi & Co Ltd | インターロイキン−2組成物 |
| US20080260858A1 (en) * | 2005-02-16 | 2008-10-23 | The Board Of Trustees Of The University Of Illnois | Universal Procoagulant |
| JP2008531692A (ja) * | 2005-03-04 | 2008-08-14 | ザ・ボード・オブ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・イリノイ | 凝固及び線維素溶解カスケードのモジュレーター |
| AU2012213951B2 (en) * | 2005-04-28 | 2014-10-16 | Novo Nordisk Health Care Ag | A closed container comprising an activated factor VII polypeptide, processes for the preparation of the same, and a kit and a method for use of the kit |
| WO2006114448A2 (fr) * | 2005-04-28 | 2006-11-02 | Novo Nordisk Health Care Ag | Contenant ferme renfermant un polypeptide de facteur vii active, processus de preparation dudit contenant, kit associe, et procede d'utilisation dudit kit |
| EP1899462B1 (fr) * | 2005-07-02 | 2011-03-09 | Arecor Limited | Systemes aqueux stables comprenant des proteines |
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| BRPI0620316A2 (pt) * | 2005-12-21 | 2011-11-08 | Wyeth Corp | formulações de proteìnas com viscosidades reduzida e seus usos |
| US9675696B2 (en) * | 2006-11-14 | 2017-06-13 | Warsaw Orthopedic, Inc. | Method and use for increasing efficacy of anti-adhesive compositions in controlling inflammation and pain |
| US9186323B2 (en) | 2007-05-02 | 2015-11-17 | Novo Nordisk Healthcare Ag | High concentration factor VII polypeptide formulations comprising an aromatic preservative and an antioxidant |
| ES2520046T3 (es) * | 2007-08-24 | 2014-11-11 | Novo Nordisk Health Care Ag | Reducción del contenido de dímeros en composiciones de polipéptidos del factor VII por tratamiento térmico |
| WO2009046194A2 (fr) | 2007-10-05 | 2009-04-09 | The Board Of Trustees Of The University Of Illinois | Produit d'étanchéité de fibrine |
| WO2009061697A1 (fr) | 2007-11-09 | 2009-05-14 | The Board Of Trustees Of The University Of Illinois | Antagoniste d'anticoagulant et procoagulant anti-hémophilique |
| CN102007143B (zh) | 2008-01-09 | 2015-08-26 | 塞诺菲-安万特德国有限公司 | 具有超延迟时效特征的新型胰岛素衍生物 |
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| CN102256618A (zh) | 2008-10-17 | 2011-11-23 | 赛诺菲-安万特德国有限公司 | 胰岛素和glp-1激动剂的组合 |
| PL2451437T3 (pl) * | 2009-07-06 | 2017-05-31 | Sanofi-Aventis Deutschland Gmbh | Wodne preparaty insuliny zawierające metioninę |
| TR201809460T4 (tr) | 2009-11-13 | 2018-07-23 | Sanofi Aventis Deutschland | Bir GLP- 1-agonisti, bir insülin ve metiyonin içeren farmasötik bileşim. |
| NZ599847A (en) | 2009-11-13 | 2013-09-27 | Sanofi Aventis Deutschland | Pharmaceutical composition comprising a glp-1 agonist and methionine |
| US9956165B2 (en) * | 2010-03-01 | 2018-05-01 | Cytodyn Inc. | Concentrated protein formulations and uses thereof |
| WO2012028172A1 (fr) | 2010-08-30 | 2012-03-08 | Sanofi-Aventis Deutschland Gmbh | Utilisation de lixisenatide pour fabrication de médicament pour traitement du diabète sucré de type 2 |
| US9821032B2 (en) | 2011-05-13 | 2017-11-21 | Sanofi-Aventis Deutschland Gmbh | Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin |
| TWI559929B (en) | 2011-09-01 | 2016-12-01 | Sanofi Aventis Deutschland | Pharmaceutical composition for use in the treatment of a neurodegenerative disease |
| US9087234B2 (en) * | 2013-03-15 | 2015-07-21 | Nike, Inc. | Monitoring fitness using a mobile device |
| EA028016B1 (ru) * | 2013-06-06 | 2017-09-29 | Общество с ограниченной ответственностью "Гематологическая Корпорация" (ООО "ГемаКор") | Набор для измерения параметров системы гемостаза в образце крови или ее компонентов |
| PE20171622A1 (es) | 2014-12-12 | 2017-11-02 | Sanofi Aventis Deutschland | Formulacion de relacion fija de insulina glargina/lixisenatida |
| TWI748945B (zh) | 2015-03-13 | 2021-12-11 | 德商賽諾菲阿凡提斯德意志有限公司 | 第2型糖尿病病患治療 |
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| SG11202010549PA (en) * | 2018-04-24 | 2020-11-27 | Gore & Ass | Medical delivery devices with inhibited oxygen permeation |
| WO2021030787A1 (fr) | 2019-08-15 | 2021-02-18 | Catalyst Biosciences, Inc. | Polypeptides de facteur vii modifiés pour une administration sous-cutanée et un traitement à la demande |
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-
2002
- 2002-12-20 AU AU2002351756A patent/AU2002351756A1/en not_active Abandoned
- 2002-12-20 CA CA2470511A patent/CA2470511C/fr not_active Expired - Fee Related
- 2002-12-20 WO PCT/DK2002/000895 patent/WO2003055512A1/fr not_active Ceased
- 2002-12-20 PL PL02370652A patent/PL370652A1/xx unknown
- 2002-12-20 RU RU2004122398/15A patent/RU2357751C2/ru not_active IP Right Cessation
- 2002-12-20 IL IL16223902A patent/IL162239A0/xx unknown
- 2002-12-20 JP JP2003556088A patent/JP2005530683A/ja active Pending
- 2002-12-20 CN CNA028258770A patent/CN1607958A/zh active Pending
- 2002-12-20 EP EP02787470A patent/EP1458408B1/fr not_active Expired - Lifetime
- 2002-12-20 DE DE60232017T patent/DE60232017D1/de not_active Expired - Lifetime
- 2002-12-20 BR BR0215216-9A patent/BR0215216A/pt active Search and Examination
- 2002-12-20 ES ES02787470T patent/ES2325653T3/es not_active Expired - Lifetime
- 2002-12-20 HU HU0402315A patent/HUP0402315A3/hu unknown
- 2002-12-20 AT AT02787470T patent/ATE428439T1/de not_active IP Right Cessation
-
2003
- 2003-06-24 US US10/602,838 patent/US8022031B2/en not_active Expired - Fee Related
-
2011
- 2011-09-14 US US13/232,322 patent/US8461116B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003055512A1 (fr) | 2003-07-10 |
| HUP0402315A2 (hu) | 2005-02-28 |
| RU2357751C2 (ru) | 2009-06-10 |
| ES2325653T3 (es) | 2009-09-11 |
| RU2004122398A (ru) | 2005-03-20 |
| HUP0402315A3 (en) | 2009-03-30 |
| US20120004176A1 (en) | 2012-01-05 |
| CA2470511C (fr) | 2014-05-27 |
| EP1458408B1 (fr) | 2009-04-15 |
| JP2005530683A (ja) | 2005-10-13 |
| AU2002351756A1 (en) | 2003-07-15 |
| US20040037893A1 (en) | 2004-02-26 |
| PL370652A1 (en) | 2005-05-30 |
| CA2470511A1 (fr) | 2003-07-10 |
| BR0215216A (pt) | 2004-11-16 |
| EP1458408A1 (fr) | 2004-09-22 |
| US8461116B2 (en) | 2013-06-11 |
| US8022031B2 (en) | 2011-09-20 |
| ATE428439T1 (de) | 2009-05-15 |
| DE60232017D1 (de) | 2009-05-28 |
| CN1607958A (zh) | 2005-04-20 |
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