IL164002A0 - Sulfonyl-derivatives as novel inhibitors of histone deacetylase - Google Patents

Sulfonyl-derivatives as novel inhibitors of histone deacetylase

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Publication number
IL164002A0
IL164002A0 IL16400203A IL16400203A IL164002A0 IL 164002 A0 IL164002 A0 IL 164002A0 IL 16400203 A IL16400203 A IL 16400203A IL 16400203 A IL16400203 A IL 16400203A IL 164002 A0 IL164002 A0 IL 164002A0
Authority
IL
Israel
Prior art keywords
sulfonyl
derivatives
histone deacetylase
novel inhibitors
inhibitors
Prior art date
Application number
IL16400203A
Other languages
English (en)
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of IL164002A0 publication Critical patent/IL164002A0/xx

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    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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    • A61K31/402—1-aryl substituted, e.g. piretanide
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