IL82982A - Process for the preparation of n-alkyl-2-phenylimidazo(1,2-a)pyridine-3-acetamides - Google Patents

Process for the preparation of n-alkyl-2-phenylimidazo(1,2-a)pyridine-3-acetamides

Info

Publication number: IL82982A
Authority: IL; Israel
Prior art keywords: phenylimidazo; acetamides; pyridine; alkyl; preparation
Prior art date: 1986-06-27

Application number

IL82982A

Other languages

English (en)

Other versions

IL82982A0 (en

Original Assignee

Synthelabo

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-06-27

Filing date

1987-06-24

Publication date

1992-03-29

1987-06-24 Application filed by Synthelabo filed Critical Synthelabo

1987-12-20 Publication of IL82982A0 publication Critical patent/IL82982A0/xx

1992-03-29 Publication of IL82982A publication Critical patent/IL82982A/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

IL82982A 1986-06-27 1987-06-24 Process for the preparation of n-alkyl-2-phenylimidazo(1,2-a)pyridine-3-acetamides IL82982A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR8609330A FR2600650B1 (fr)	1986-06-27	1986-06-27	Procede de preparation d'imidazopyridines et composes intermediaires

Publications (2)

Publication Number	Publication Date
IL82982A0 IL82982A0 (en)	1987-12-20
IL82982A true IL82982A (en)	1992-03-29

Family

ID=9336785

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL82982A IL82982A (en)	1986-06-27	1987-06-24	Process for the preparation of n-alkyl-2-phenylimidazo(1,2-a)pyridine-3-acetamides

Country Status (21)

Country	Link
US (1)	US4794185A (de)
EP (1)	EP0251859B1 (de)
JP (1)	JPH0653740B2 (de)
KR (1)	KR940006594B1 (de)
AR (1)	AR243188A1 (de)
AT (1)	ATE58537T1 (de)
AU (1)	AU7477287A (de)
CA (1)	CA1324138C (de)
DE (1)	DE3766300D1 (de)
DK (1)	DK169505B1 (de)
ES (1)	ES2019646B3 (de)
FI (1)	FI872850A7 (de)
FR (1)	FR2600650B1 (de)
GR (1)	GR3001118T3 (de)
HU (1)	HU204826B (de)
IE (1)	IE60467B1 (de)
IL (1)	IL82982A (de)
NO (1)	NO167392C (de)
NZ (1)	NZ220853A (de)
PT (1)	PT85188B (de)
ZA (1)	ZA874643B (de)

Families Citing this family (47)

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ES2032455T3 (es) *	1986-01-22	1993-02-16	Synthelabo	Procedimiento para preparar derivados de 3-acilaminometil-imidazo (-1,2-a)piridinas.
FR2615513B1 (fr) *	1987-05-21	1989-07-13	Synthelabo	Derives d'acylaminomethyl-3 tetrahydro-5,6,7,8 imidazo(1,2-a)pyridines, leur preparation et leur application en therapeutique
DE69910795T2 (de)	1998-06-09	2004-06-17	Takeda Chemical Industries, Ltd.	Pharmazeutische kombination mit einer trizyclischen verbindung und mindestens einer von zolpidem, zopiclone und brotizolam, zur behandlung oder verhinderung von schlafstörungen
ES2151834B1 (es) *	1998-08-06	2001-08-16	Sint Quimica Sa	Procedimiento para preparar n,n,6-trimetil-2-(4-metilfenil)-imidazo-(1,2-a)-piridina-3-acetamida y sus sales.
EP1038875B1 (de)	1999-03-25	2003-06-04	Synthon B.V.	Imidazopyridinderivate und Verfahren zu ihrer Herstellung
DE60020814T2 (de) *	1999-03-25	2006-05-04	Synthon B.V.	Zolpidem salze
US6333345B1 (en) *	1999-05-14	2001-12-25	Sepracor, Inc.	Methods of using and compositions comprising N-desmethylzolpidem
US6399621B1 (en)	1999-08-10	2002-06-04	American Cyanamid Company	N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1, 5-α]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto
US6485746B1 (en)	2000-08-25	2002-11-26	Neurocrine Biosciences, Inc.	Controlled-release sedative-hypnotic compositions and methods related thereto
US20030091632A1 (en) *	1999-08-26	2003-05-15	Neurocrine Biosciences, Inc.	Controlled-release sedative-hypnotic compositions and methods related thereto
US6384221B1 (en)	1999-09-02	2002-05-07	Neurocrine Biosciences, Inc.	Polymorphs of N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1,5-α]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto
EP1272181A2 (de) *	2000-04-13	2003-01-08	Synthon B.V.	Arzneizubereitungen mit gesteuerter wirkstoffabgabe enthaltend ein hypnotikum
EP1473036B1 (de) *	2000-04-24	2006-08-09	Teva Pharmaceutical Industries Ltd.	Zolpidem Hemitartrat Solvat
PL358548A1 (en) *	2000-04-24	2004-08-09	Teva Pharmaceutical Industries Ltd.	Zolpidem hemitartrate
IT1318624B1 (it)	2000-07-14	2003-08-27	Dinamite Dipharma S P A In For	Processo per la preparazione di 2-fenil-imidazo (1,2-a)piridin-3-acetammidi.
WO2002014306A1 (en) *	2000-08-17	2002-02-21	Cilag Ag	Process for the preparation of imidazopyridines
US6596731B2 (en)	2001-03-27	2003-07-22	Hoffmann-La Roche Inc.	Substituted imidazo[1,2-A] pyridine derivatives
US20020183522A1 (en)	2001-05-03	2002-12-05	Markus Sauter	Process for preparing zolpidem
DE10121638A1 (de) *	2001-05-03	2002-11-14	Boehringer Ingelheim Pharma	Verfahren zur Herstellung von Imidazopyridinen
WO2004007496A1 (en) *	2002-07-15	2004-01-22	Scinopharm Taiwan, Ltd.	Process for the preparation of imidazo(1,2-a)pyridine-3-acetamides
ES2320758T3 (es)	2002-12-18	2009-05-28	Mallinckrodt Inc.	Sintesis de heteroaril acetamidas.
US20040241100A1 (en) *	2003-03-17	2004-12-02	Fabre Kramer Pharmaceutical, Inc.	Nasally administrable compositions of zolpidem and methods of use
GB0311457D0 (en) *	2003-05-19	2003-06-25	Sciencom Ltd	New therapeutic use
WO2005060968A1 (en)	2003-12-11	2005-07-07	Sepracor Inc.	Combination of a sedative and a neurotransmitter modulator, and methods for improving sleep quality and treating depression
ATE451371T1 (de) *	2004-06-22	2009-12-15	Mallinckrodt Inc	Synthese von heteroarylacetamiden aus reaktionsmischungen mit reduziertem wassergehalt
WO2006008636A2 (en) *	2004-07-16	2006-01-26	Ranbaxy Laboratories Limited	Processes for the preparation of zolpidem and its hemitartrate
EP2258359A3 (de)	2005-08-26	2011-04-06	Braincells, Inc.	Neurogenese durch Modulation des Muscarinrezeptors mit Sabcomelin
JP2009506069A (ja)	2005-08-26	2009-02-12	ブレインセルス，インコーポレイティド	ムスカリン性受容体調節による神経発生
WO2007040995A1 (en) *	2005-10-03	2007-04-12	Mallinckrodt Inc.	Process for preparing zolpidem hemitartrate and tartrate polymorphs
CA2626242A1 (en) *	2005-10-17	2007-04-26	Mallinckrodt Inc.	Polymorph transformation of zolpidem in tablet matrix
US7985756B2 (en)	2005-10-21	2011-07-26	Braincells Inc.	Modulation of neurogenesis by PDE inhibition
WO2007053596A1 (en)	2005-10-31	2007-05-10	Braincells, Inc.	Gaba receptor mediated modulation of neurogenesis
DE602006008339D1 (en)	2005-11-18	2009-09-17	Synhton B V	Zolpidemtabletten
US20100216734A1 (en)	2006-03-08	2010-08-26	Braincells, Inc.	Modulation of neurogenesis by nootropic agents
WO2007134077A2 (en)	2006-05-09	2007-11-22	Braincells, Inc.	5 ht receptor mediated neurogenesis
WO2007134136A2 (en)	2006-05-09	2007-11-22	Braincells, Inc.	Neurogenesis by modulating angiotensin
EP2068872A1 (de) *	2006-09-08	2009-06-17	Braincells, Inc.	Kombinationen mit einem 4-acylaminopyridin-derivat
US20080145425A1 (en) *	2006-12-15	2008-06-19	Pliva Research & Development Limited	Pharmaceutical composition of zolpidem
WO2010099217A1 (en)	2009-02-25	2010-09-02	Braincells, Inc.	Modulation of neurogenesis using d-cycloserine combinations
CN103360387B (zh) *	2012-03-28	2016-12-14	江苏豪森药业集团有限公司	一种制备化合物唑吡坦的方法
KR101704589B1 (ko) *	2016-07-12	2017-02-08	주식회사 뉴트라팜텍	후박 추출물 및 신이 추출물의 혼합물을 유효성분으로 함유하는 치주조직 성장 촉진용 및 치주염 예방 또는 치료용 약학적 조성물
CN107793415A (zh) *	2016-12-01	2018-03-13	湖南省食品药品检验研究院	酒石酸唑吡坦杂质的合成方法
CN106749237A (zh) *	2016-12-28	2017-05-31	江苏豪森药业集团有限公司	酒石酸唑吡坦及其中间体的制备方法
CN114057725B (zh) *	2020-07-31	2024-01-16	株洲千金药业股份有限公司	一种酒石酸唑吡坦的合成方法
CN114057727B (zh) *	2020-07-31	2024-02-27	株洲千金药业股份有限公司	一种唑吡坦中间体的合成方法
CN114057726A (zh) *	2020-07-31	2022-02-18	株洲千金药业股份有限公司	一种唑吡坦盐酸盐的合成方法
CN114249668B (zh) *	2020-09-25	2024-08-23	鲁南制药集团股份有限公司	一种唑吡坦中间体n,n-二甲基-2-氧乙酰胺的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GR68765B (de) *	1979-06-20	1982-02-17	Rohm & Haas
FR2492382A1 (fr) *	1980-10-22	1982-04-23	Synthelabo	Derives d'imidazo (1,2-a) pyridine, leur preparation et leur application en therapeutique

1986
- 1986-06-27 FR FR8609330A patent/FR2600650B1/fr not_active Expired
1987
- 1987-06-17 EP EP87401353A patent/EP0251859B1/de not_active Expired - Lifetime
- 1987-06-17 ES ES87401353T patent/ES2019646B3/es not_active Expired - Lifetime
- 1987-06-17 DE DE8787401353T patent/DE3766300D1/de not_active Expired - Lifetime
- 1987-06-17 AT AT87401353T patent/ATE58537T1/de active
- 1987-06-24 IL IL82982A patent/IL82982A/xx not_active IP Right Cessation
- 1987-06-26 HU HU872909A patent/HU204826B/hu unknown
- 1987-06-26 US US07/066,530 patent/US4794185A/en not_active Expired - Lifetime
- 1987-06-26 ZA ZA874643A patent/ZA874643B/xx unknown
- 1987-06-26 IE IE172387A patent/IE60467B1/en not_active IP Right Cessation
- 1987-06-26 CA CA000540712A patent/CA1324138C/en not_active Expired - Fee Related
- 1987-06-26 NO NO872682A patent/NO167392C/no not_active IP Right Cessation
- 1987-06-26 KR KR1019870006538A patent/KR940006594B1/ko not_active Expired - Lifetime
- 1987-06-26 JP JP62160827A patent/JPH0653740B2/ja not_active Expired - Lifetime
- 1987-06-26 FI FI872850A patent/FI872850A7/fi not_active Application Discontinuation
- 1987-06-26 PT PT85188A patent/PT85188B/pt unknown
- 1987-06-26 DK DK328187A patent/DK169505B1/da not_active IP Right Cessation
- 1987-06-26 NZ NZ220853A patent/NZ220853A/xx unknown
- 1987-06-26 AU AU74772/87A patent/AU7477287A/en not_active Abandoned
- 1987-06-26 AR AR87307995A patent/AR243188A1/es active
1990
- 1990-11-28 GR GR90400982T patent/GR3001118T3/el unknown

Also Published As

Publication number	Publication date
NZ220853A (en)	1989-09-27
GR3001118T3 (en)	1992-05-12
IL82982A0 (en)	1987-12-20
FI872850A7 (fi)	1987-12-28
IE871723L (en)	1987-12-27
ATE58537T1 (de)	1990-12-15
EP0251859A2 (de)	1988-01-07
HUT44547A (en)	1988-03-28
CA1324138C (en)	1993-11-09
NO167392B (no)	1991-07-22
EP0251859A3 (en)	1989-07-19
DK328187A (da)	1987-12-28
PT85188B (pt)	1990-03-30
KR880000433A (ko)	1988-03-25
US4794185A (en)	1988-12-27
AR243188A1 (es)	1993-07-30
NO872682L (no)	1987-12-28
NO167392C (no)	1991-10-30
ZA874643B (en)	1988-02-24
DK169505B1 (da)	1994-11-14
HU204826B (en)	1992-02-28
DK328187D0 (da)	1987-06-26
FR2600650B1 (fr)	1988-09-09
PT85188A (fr)	1987-07-01
FR2600650A1 (fr)	1987-12-31
DE3766300D1 (de)	1991-01-03
EP0251859B1 (de)	1990-11-22
AU7477287A (en)	1988-01-07
IE60467B1 (en)	1994-07-13
ES2019646B3 (es)	1991-07-01
JPH0653740B2 (ja)	1994-07-20
FI872850A0 (fi)	1987-06-26
JPS638384A (ja)	1988-01-14
KR940006594B1 (ko)	1994-07-23
NO872682D0 (no)	1987-06-26

Legal Events

Date	Code	Title
1997-11-20	KB	Patent renewed
2001-08-26	KB	Patent renewed
2007-08-19	EXP	Patent expired

Publication	Publication Date	Title
EP0302020A3 (en)	1990-08-01	Process for the preparation of 2,2,6,6-tetramethyl-4-piperidyl-amines
PT86309A (en)	1988-01-01	Process for the preparation of substituted basic 2-aminotetralins
AR243188A1 (es)	1993-07-30	Procedimiento para preparar imidazopiridinas y compuestos intermediarios.
PT85239A (en)	1987-08-01	Process for the preparation of-aryl-phenyl-ethyl-1h-1,2,4-triazole-1-propanenitriles
PT84831A (en)	1987-06-01	Process for the preparation of new pyrazol-3-amines
KR950010075B1 (en)	1995-09-06	Process for the preparation of 1,2,3,6-tetrahydro-5-nitro-pyrimidine derivatives
DE3662256D1 (en)	1989-04-13	Process for the preparation of (2,2)-paracyclophane
GR3001619T3 (en)	1992-11-23	Process for the preparation of (2,2)-paracyclophane
DE3569375D1 (en)	1989-05-18	Process for the preparation of 1,2-benzisothiazolones
IL82858A0 (en)	1987-12-20	Process for the preparation of 1,2,5,6,9,10-hexabromo-cyclododecane
IL86646A (en)	1992-02-16	Process for the preparation of 5,11-di-and 5,6,11,12-tetraphenylnaphthacenes
EP0255904A3 (en)	1988-08-17	Process for the preparation of dihydrocyclocitral
PT83636A (en)	1986-11-01	Process for the preparation of 5-aryl-2,4-dialkyl-3h-1,2,4-triazole-3-thiones
EP0264089A3 (en)	1989-12-27	Process for the preparation of sulphatobetaines
PT85392A (en)	1987-08-01	Process for the preparation of 2,4-diamino-3-oxy-6-piperidylpurimidine
AR242576A1 (es)	1993-04-30	Proceso para la preparacion de alfa-n-¡(hipoxantin-9-il)-pentiloxicarbonil¿-arginina.
PT85190A (en)	1987-07-01	Process for the preparation of mercaptoacylproline
DE3760307D1 (en)	1989-08-17	Process for the preparation of 1,1,2-trialkoxyethane
PT83799A (en)	1986-12-01	Process for the preparation of novel 2,2:-bi-1h-imidazoles
GB2191773B (en)	1990-02-14	Process for the preparation of 4-alkoxy-3-pyrrolin-2-ones
EP0240741A3 (en)	1988-10-05	Process for the preparation of inulase
ZA875689B (en)	1988-04-27	Process for the preparation of 2,4-diamino-5-benzylpyrimidines
EP0297239A3 (en)	1990-05-02	Process for the preparation of hexadiin(2,4)-diol-1,6
PH24488A (en)	1990-07-18	Process for the preparation of aryl-pyrido (1,4)-benzodiazepines
PT85185A (en)	1987-07-01	Process for the preparation of 3,7-dihydro-3-n-propyl-1h-purine-2,6-dione