ZA874643B - A process for the preparation of imidazopyridines and intermediate compounds - Google Patents

A process for the preparation of imidazopyridines and intermediate compounds

Info

Publication number
ZA874643B
ZA874643B ZA874643A ZA874643A ZA874643B ZA 874643 B ZA874643 B ZA 874643B ZA 874643 A ZA874643 A ZA 874643A ZA 874643 A ZA874643 A ZA 874643A ZA 874643 B ZA874643 B ZA 874643B
Authority
ZA
South Africa
Prior art keywords
imidazopyridines
preparation
intermediate compounds
compounds
Prior art date
Application number
ZA874643A
Other languages
English (en)
Inventor
Guy Rossey
Rossey Guy
David Long
Long David
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of ZA874643B publication Critical patent/ZA874643B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
ZA874643A 1986-06-27 1987-06-26 A process for the preparation of imidazopyridines and intermediate compounds ZA874643B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8609330A FR2600650B1 (fr) 1986-06-27 1986-06-27 Procede de preparation d'imidazopyridines et composes intermediaires

Publications (1)

Publication Number Publication Date
ZA874643B true ZA874643B (en) 1988-02-24

Family

ID=9336785

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA874643A ZA874643B (en) 1986-06-27 1987-06-26 A process for the preparation of imidazopyridines and intermediate compounds

Country Status (21)

Country Link
US (1) US4794185A (de)
EP (1) EP0251859B1 (de)
JP (1) JPH0653740B2 (de)
KR (1) KR940006594B1 (de)
AR (1) AR243188A1 (de)
AT (1) ATE58537T1 (de)
AU (1) AU7477287A (de)
CA (1) CA1324138C (de)
DE (1) DE3766300D1 (de)
DK (1) DK169505B1 (de)
ES (1) ES2019646B3 (de)
FI (1) FI872850A7 (de)
FR (1) FR2600650B1 (de)
GR (1) GR3001118T3 (de)
HU (1) HU204826B (de)
IE (1) IE60467B1 (de)
IL (1) IL82982A (de)
NO (1) NO167392C (de)
NZ (1) NZ220853A (de)
PT (1) PT85188B (de)
ZA (1) ZA874643B (de)

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ATE62687T1 (de) * 1986-01-22 1991-05-15 Synthelabo Acylaminomethylimidazo(1,2-a>pyrimidinderivate, ihre herstellung und therapeutische verwendung.
FR2615513B1 (fr) * 1987-05-21 1989-07-13 Synthelabo Derives d'acylaminomethyl-3 tetrahydro-5,6,7,8 imidazo(1,2-a)pyridines, leur preparation et leur application en therapeutique
DE69910795T2 (de) 1998-06-09 2004-06-17 Takeda Chemical Industries, Ltd. Pharmazeutische kombination mit einer trizyclischen verbindung und mindestens einer von zolpidem, zopiclone und brotizolam, zur behandlung oder verhinderung von schlafstörungen
ES2151834B1 (es) * 1998-08-06 2001-08-16 Sint Quimica Sa Procedimiento para preparar n,n,6-trimetil-2-(4-metilfenil)-imidazo-(1,2-a)-piridina-3-acetamida y sus sales.
ATE297924T1 (de) * 1999-03-25 2005-07-15 Synthon Bv Zolpidem salze
PT1038875E (pt) 1999-03-25 2003-10-31 Synthon Bv Derivados de imidazopiridina e processo para os preparar
US6333345B1 (en) * 1999-05-14 2001-12-25 Sepracor, Inc. Methods of using and compositions comprising N-desmethylzolpidem
US6399621B1 (en) 1999-08-10 2002-06-04 American Cyanamid Company N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1, 5-α]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto
US6485746B1 (en) 2000-08-25 2002-11-26 Neurocrine Biosciences, Inc. Controlled-release sedative-hypnotic compositions and methods related thereto
US20030091632A1 (en) * 1999-08-26 2003-05-15 Neurocrine Biosciences, Inc. Controlled-release sedative-hypnotic compositions and methods related thereto
US6384221B1 (en) * 1999-09-02 2002-05-07 Neurocrine Biosciences, Inc. Polymorphs of N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1,5-α]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto
AU5066101A (en) * 2000-04-13 2001-10-30 Synthon B.V. Modified release formulations containing a hypnotic agent
CZ20023775A3 (cs) * 2000-04-24 2003-10-15 Teva Pharmaceutical Industries Ltd. Zolpidem hemitartrát
EP1475093B1 (de) * 2000-04-24 2006-09-06 Teva Pharmaceutical Industries Ltd. Mikronisierter zolpidem Hemitartrat
IT1318624B1 (it) 2000-07-14 2003-08-27 Dinamite Dipharma S P A In For Processo per la preparazione di 2-fenil-imidazo (1,2-a)piridin-3-acetammidi.
WO2002014306A1 (en) * 2000-08-17 2002-02-21 Cilag Ag Process for the preparation of imidazopyridines
US6596731B2 (en) 2001-03-27 2003-07-22 Hoffmann-La Roche Inc. Substituted imidazo[1,2-A] pyridine derivatives
DE10121638A1 (de) * 2001-05-03 2002-11-14 Boehringer Ingelheim Pharma Verfahren zur Herstellung von Imidazopyridinen
US20020183522A1 (en) 2001-05-03 2002-12-05 Markus Sauter Process for preparing zolpidem
EP1539751B1 (de) * 2002-07-15 2008-05-07 Scinopharm Taiwan, Ltd. Verfahren zur herstellung von imidazo(1,2-a)pyridin-3-acetamiden
EP1575952B1 (de) * 2002-12-18 2009-02-18 Mallinckrodt Inc. Synthese von heteroaryl acetamiden
US20040241100A1 (en) * 2003-03-17 2004-12-02 Fabre Kramer Pharmaceutical, Inc. Nasally administrable compositions of zolpidem and methods of use
GB0311457D0 (en) * 2003-05-19 2003-06-25 Sciencom Ltd New therapeutic use
US20050176680A1 (en) 2003-12-11 2005-08-11 Sepracor, Inc. Combination of sedative and a neurotransmitter modulator, and methods for improving sleep quality and treating depression
CA2571491A1 (en) * 2004-06-22 2006-01-19 Mallinckrodt, Inc. Synthesis of heteroaryl acetamides from reaction mixtures having reduced water content
WO2006008636A2 (en) * 2004-07-16 2006-01-26 Ranbaxy Laboratories Limited Processes for the preparation of zolpidem and its hemitartrate
EP1928437A2 (de) 2005-08-26 2008-06-11 Braincells, Inc. Neurogenese mittels muscarinrezeptormodulation
EP2258358A3 (de) 2005-08-26 2011-09-07 Braincells, Inc. Neurogenese mit Acetylcholinesterasehemmer
EP1948655A1 (de) * 2005-10-03 2008-07-30 Mallinckrodt, Inc. Verfahren zur herstellung von zolpidemhemitartrat- und- tartratpolymorphen
WO2007047047A2 (en) * 2005-10-17 2007-04-26 Mallinckrodt Inc. Polymorph transformation of zolpidem in tablet matrix
EP1940389A2 (de) 2005-10-21 2008-07-09 Braincells, Inc. Modulation von neurogenese durch pde-hemmung
US20070112017A1 (en) 2005-10-31 2007-05-17 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
AU2006322314A1 (en) 2005-11-18 2007-06-14 Synthon B.V. Zolpidem tablets
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
AU2007249399A1 (en) 2006-05-09 2007-11-22 Braincells, Inc. Neurogenesis by modulating angiotensin
WO2007134077A2 (en) 2006-05-09 2007-11-22 Braincells, Inc. 5 ht receptor mediated neurogenesis
EP2068872A1 (de) * 2006-09-08 2009-06-17 Braincells, Inc. Kombinationen mit einem 4-acylaminopyridin-derivat
US20080145425A1 (en) * 2006-12-15 2008-06-19 Pliva Research & Development Limited Pharmaceutical composition of zolpidem
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
CN103360387B (zh) * 2012-03-28 2016-12-14 江苏豪森药业集团有限公司 一种制备化合物唑吡坦的方法
KR101704589B1 (ko) * 2016-07-12 2017-02-08 주식회사 뉴트라팜텍 후박 추출물 및 신이 추출물의 혼합물을 유효성분으로 함유하는 치주조직 성장 촉진용 및 치주염 예방 또는 치료용 약학적 조성물
CN107793415A (zh) * 2016-12-01 2018-03-13 湖南省食品药品检验研究院 酒石酸唑吡坦杂质的合成方法
CN106749237A (zh) * 2016-12-28 2017-05-31 江苏豪森药业集团有限公司 酒石酸唑吡坦及其中间体的制备方法
CN114057725B (zh) * 2020-07-31 2024-01-16 株洲千金药业股份有限公司 一种酒石酸唑吡坦的合成方法
CN114057726A (zh) * 2020-07-31 2022-02-18 株洲千金药业股份有限公司 一种唑吡坦盐酸盐的合成方法
CN114057727B (zh) * 2020-07-31 2024-02-27 株洲千金药业股份有限公司 一种唑吡坦中间体的合成方法
CN114249668B (zh) * 2020-09-25 2024-08-23 鲁南制药集团股份有限公司 一种唑吡坦中间体n,n-二甲基-2-氧乙酰胺的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR68765B (de) * 1979-06-20 1982-02-17 Rohm & Haas
FR2492382A1 (fr) * 1980-10-22 1982-04-23 Synthelabo Derives d'imidazo (1,2-a) pyridine, leur preparation et leur application en therapeutique

Also Published As

Publication number Publication date
CA1324138C (en) 1993-11-09
EP0251859A2 (de) 1988-01-07
NO167392B (no) 1991-07-22
IL82982A (en) 1992-03-29
IL82982A0 (en) 1987-12-20
JPS638384A (ja) 1988-01-14
AU7477287A (en) 1988-01-07
DK169505B1 (da) 1994-11-14
JPH0653740B2 (ja) 1994-07-20
EP0251859A3 (en) 1989-07-19
DK328187A (da) 1987-12-28
HU204826B (en) 1992-02-28
KR940006594B1 (ko) 1994-07-23
FI872850A7 (fi) 1987-12-28
PT85188B (pt) 1990-03-30
ES2019646B3 (es) 1991-07-01
HUT44547A (en) 1988-03-28
AR243188A1 (es) 1993-07-30
NZ220853A (en) 1989-09-27
NO872682L (no) 1987-12-28
FR2600650A1 (fr) 1987-12-31
PT85188A (fr) 1987-07-01
FI872850A0 (fi) 1987-06-26
NO167392C (no) 1991-10-30
GR3001118T3 (en) 1992-05-12
ATE58537T1 (de) 1990-12-15
DE3766300D1 (de) 1991-01-03
US4794185A (en) 1988-12-27
IE60467B1 (en) 1994-07-13
EP0251859B1 (de) 1990-11-22
NO872682D0 (no) 1987-06-26
FR2600650B1 (fr) 1988-09-09
KR880000433A (ko) 1988-03-25
IE871723L (en) 1987-12-27
DK328187D0 (da) 1987-06-26

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