IL83059A - Stable hydrate of cephalosporin derivative,process for the preparation thereof and a gelatin capsule composition containing the same - Google Patents

Stable hydrate of cephalosporin derivative,process for the preparation thereof and a gelatin capsule composition containing the same

Info

Publication number
IL83059A
IL83059A IL83059A IL8305987A IL83059A IL 83059 A IL83059 A IL 83059A IL 83059 A IL83059 A IL 83059A IL 8305987 A IL8305987 A IL 8305987A IL 83059 A IL83059 A IL 83059A
Authority
IL
Israel
Prior art keywords
preparation
composition containing
same
gelatin capsule
capsule composition
Prior art date
Application number
IL83059A
Other languages
English (en)
Other versions
IL83059A0 (en
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP61156954A external-priority patent/JP2544113B2/ja
Priority claimed from JP21626086A external-priority patent/JPH0717651B2/ja
Application filed by Shionogi & Co filed Critical Shionogi & Co
Publication of IL83059A0 publication Critical patent/IL83059A0/xx
Publication of IL83059A publication Critical patent/IL83059A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicinal Preparation (AREA)
IL83059A 1986-07-02 1987-07-01 Stable hydrate of cephalosporin derivative,process for the preparation thereof and a gelatin capsule composition containing the same IL83059A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP61156954A JP2544113B2 (ja) 1986-07-02 1986-07-02 安定なカプセル製剤
JP21626086A JPH0717651B2 (ja) 1986-09-12 1986-09-12 経口投与用セフアロスポリン水和物結晶

Publications (2)

Publication Number Publication Date
IL83059A0 IL83059A0 (en) 1987-12-31
IL83059A true IL83059A (en) 1992-03-29

Family

ID=26484565

Family Applications (1)

Application Number Title Priority Date Filing Date
IL83059A IL83059A (en) 1986-07-02 1987-07-01 Stable hydrate of cephalosporin derivative,process for the preparation thereof and a gelatin capsule composition containing the same

Country Status (27)

Country Link
US (2) US4812561A (fr)
KR (1) KR950005302B1 (fr)
CN (1) CN1015106B (fr)
AR (1) AR243893A1 (fr)
AT (1) AT392472B (fr)
AU (1) AU594167B2 (fr)
BE (1) BE1001691A4 (fr)
CA (1) CA1283405C (fr)
CH (1) CH672788A5 (fr)
DE (1) DE3721913A1 (fr)
DK (1) DK161080C (fr)
ES (2) ES2004952A6 (fr)
FI (1) FI89052C (fr)
FR (1) FR2601014B1 (fr)
GB (1) GB2192183B (fr)
GR (1) GR871014B (fr)
HK (1) HK47893A (fr)
HU (1) HU200777B (fr)
IE (1) IE59613B1 (fr)
IL (1) IL83059A (fr)
IT (1) IT1211469B (fr)
NL (1) NL193136C (fr)
NO (1) NO170889C (fr)
NZ (1) NZ220764A (fr)
PL (1) PL159180B1 (fr)
RU (1) RU1829932C (fr)
SE (1) SE466257B (fr)

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US20020197314A1 (en) * 2001-02-23 2002-12-26 Rudnic Edward M. Anti-fungal composition
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US8062672B2 (en) * 2003-08-12 2011-11-22 Shionogi Inc. Antibiotic product, use and formulation thereof
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US8357394B2 (en) 2005-12-08 2013-01-22 Shionogi Inc. Compositions and methods for improved efficacy of penicillin-type antibiotics
US8778924B2 (en) * 2006-12-04 2014-07-15 Shionogi Inc. Modified release amoxicillin products
US8299052B2 (en) * 2006-05-05 2012-10-30 Shionogi Inc. Pharmaceutical compositions and methods for improved bacterial eradication
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US8470834B2 (en) 2008-08-20 2013-06-25 Merck Sharp & Dohme Corp. AZO-substituted pyridine and pyrimidine derivatives and their use in treating viral infections
EP2326627A1 (fr) 2008-08-20 2011-06-01 Schering Corporation Dérivés de pyridine et pyrimidine substituées et leur utilisation dans le traitement d'infections virales
ES2439009T3 (es) 2008-08-20 2014-01-21 Merck Sharp & Dohme Corp. Derivados de piridina y pirimidina sustituidos con etenilo y su uso en el tratamiento de infecciones virales
JP2012528195A (ja) 2009-05-29 2012-11-12 メルク・シャープ・アンド・ドーム・コーポレーション Ｃ型肝炎などの疾患を処置するための３つの結合アリール部分で構成された抗菌性化合物
PT2451445T (pt) 2009-07-06 2019-07-10 Boehringer Ingelheim Int Processo para secagem de bibw2992, dos seus sais e de formulações farmacêuticas sólidas compreendendo este ingrediente ativo
EP2503881B1 (fr) 2009-11-25 2015-05-13 Merck Sharp & Dohme Corp. Composés tricycliques fusionnés et leurs dérivés utiles pour le traitement de maladies virales
AU2010341537A1 (en) 2009-12-22 2012-08-09 Merck Sharp & Dohme Corp. Fused Tricyclic Compounds and methods of use thereof for the treatment of viral diseases
WO2011103441A1 (fr) 2010-02-18 2011-08-25 Schering Corporation Dérivés de pyridine et pyrimidine substitués et leur utilisation dans le traitement d'infections virales
EP2545060B1 (fr) 2010-03-09 2015-11-25 Merck Sharp & Dohme Corp. Composés de silyle tricycliques fusionnés et leurs procédés d'utilisation pour le traitement de maladies virales
WO2011139253A2 (fr) 2010-05-04 2011-11-10 Mahmut Bilgic Compositions pharmaceutiques comprenant du ceftibutène
AU2011286276A1 (en) 2010-07-26 2013-01-24 Merck Sharp & Dohme Corp. Substituted biphenylene compounds and methods of use thereof for the treatment of viral diseases
JP2013540122A (ja) 2010-09-29 2013-10-31 メルク・シャープ・エンド・ドーム・コーポレイション 縮合四環式化合物誘導体およびウィルス疾患治療のためのそれの使用方法
BR112013026345A2 (pt) 2011-04-13 2019-04-24 Merck Sharp & Dohe Corp. composto, composição farmacêutica, uso de um composto, e, método para tratar um paciente infectado com hcv
EP2697242B1 (fr) 2011-04-13 2018-10-03 Merck Sharp & Dohme Corp. Dérivés de nucléosides à substitution 2'-azido et leurs procédés d'utilisation pour le traitement de maladies virales
WO2013033899A1 (fr) 2011-09-08 2013-03-14 Merck Sharp & Dohme Corp. Composés benzofuranes substitués et leur procédés d'utilisation pour le traitement de maladies virales
WO2013033901A1 (fr) 2011-09-08 2013-03-14 Merck Sharp & Dohme Corp. Dérivés benzofuranes substitués par un hétérocycle et leurs procédés d'utilisation pour le traitement de maladies virales
WO2013033900A1 (fr) 2011-09-08 2013-03-14 Merck Sharp & Dohme Corp. Composés hétérocycliques tétracycliques et leurs procédés d'utilisation pour le traitement de maladies virales
EP2755981A4 (fr) 2011-09-14 2015-03-25 Merck Sharp & Dohme Composés hétérocycliques contenant un silyle et méthodes d'utilisation desdits composés pour traiter les maladies virales
WO2013151518A1 (fr) * 2012-04-04 2013-10-10 Mahmut Bilgic Formulations de capsule comprenant du ceftibutène
EP2815743A1 (fr) 2013-06-21 2014-12-24 Sanovel Ilac Sanayi ve Ticaret A.S. Formulations comprenant du ceftibutène
EP3063140A4 (fr) 2013-10-30 2017-11-08 Merck Sharp & Dohme Corp. Pseudopolymorphes d'un inhibiteur de la protéine ns5a du vhc et leurs utilisations
US9242965B2 (en) 2013-12-31 2016-01-26 Boehringer Ingelheim International Gmbh Process for the manufacture of (E)-4-N,N-dialkylamino crotonic acid in HX salt form and use thereof for synthesis of EGFR tyrosine kinase inhibitors
CN103948932B (zh) * 2014-04-17 2016-03-16 海南日中天制药有限公司 一种头孢克肟组合物及其制备方法
EP3031450A1 (fr) 2014-12-12 2016-06-15 Sanovel Ilac Sanayi ve Ticaret A.S. Compositions de gélules de ceftibutène
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CN106432272A (zh) * 2016-09-21 2017-02-22 临沂草之美医药科技有限公司 一种制备治疗外科手术感染的药物头孢布烯晶体化合物的方法
CN106432271A (zh) * 2016-09-21 2017-02-22 临沂草之美医药科技有限公司 一种治疗外科手术感染的药物头孢布烯晶体化合物
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US3819620A (en) * 1972-06-01 1974-06-25 Squibb & Sons Inc 7-(d-alpha-amino-1,4-cyclohexadien-1-ylacet-amido)desacetoxycephalosporanic acid dihydrate
JPS5726692A (en) * 1980-07-22 1982-02-12 Fujisawa Pharmaceut Co Ltd Preparation of stable crystal of salt of ceftizoxime
DE3037997A1 (de) * 1980-10-08 1982-05-13 Bayer Ag (beta) -lactamantibiotika, verfahren zu deren herstellung sowie sie enthaltende mittel
YU44680B (en) * 1982-07-30 1990-12-31 Glaxo Lab Ltd Process for obtaining very pure amorphous form of cephuroxim axetile
AU575854B2 (en) * 1983-10-04 1988-08-11 Shionogi & Co., Ltd. 7beta-(carboxyalkenamido) cephalosporins
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Also Published As

Publication number Publication date
NL193136C (nl) 1998-12-04
IT1211469B (it) 1989-11-03
SE8702705L (sv) 1988-01-03
DK161080C (da) 1991-11-11
GR871014B (en) 1987-11-02
FR2601014B1 (fr) 1990-09-14
IE871738L (en) 1988-01-02
CN1015106B (zh) 1991-12-18
HK47893A (en) 1993-05-27
IE59613B1 (en) 1994-03-09
DK161080B (da) 1991-05-27
NO872729L (no) 1988-01-04
GB2192183B (en) 1990-05-16
ES2004952A6 (es) 1989-02-16
ES2008759A6 (es) 1989-08-01
DK336487D0 (da) 1987-06-30
FI89052B (fi) 1993-04-30
DE3721913A1 (de) 1988-01-07
AR243893A1 (es) 1993-09-30
SE466257B (sv) 1992-01-20
CH672788A5 (fr) 1989-12-29
SE8702705D0 (sv) 1987-06-30
ATA165887A (de) 1990-09-15
KR950005302B1 (ko) 1995-05-23
BE1001691A4 (fr) 1990-02-13
IT8767566A0 (it) 1987-07-01
FR2601014A1 (fr) 1988-01-08
FI89052C (fi) 1993-08-10
GB2192183A (en) 1988-01-06
PL159180B1 (pl) 1992-11-30
US4812561A (en) 1989-03-14
GB8715064D0 (en) 1987-08-05
HUT44257A (en) 1988-02-29
CA1283405C (fr) 1991-04-23
NO170889C (no) 1992-12-23
NL193136B (nl) 1998-08-03
AU594167B2 (en) 1990-03-01
AT392472B (de) 1991-04-10
CN87105009A (zh) 1988-03-23
NZ220764A (en) 1989-09-27
FI872903A0 (fi) 1987-07-01
NO872729D0 (no) 1987-06-30
PL266567A1 (en) 1988-07-21
AU7504087A (en) 1988-01-07
NO170889B (no) 1992-09-14
IL83059A0 (en) 1987-12-31
DK336487A (da) 1988-01-03
HU200777B (en) 1990-08-28
NL8701507A (nl) 1988-02-01
FI872903L (fi) 1988-01-03
KR880001670A (ko) 1988-04-26
RU1829932C (ru) 1993-07-23
US4933443A (en) 1990-06-12

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