IL83190A0 - 1,2,3,3a,8,8a-hexahydro-3a,8(and 1,3a,8)-di-(and tri)methylpyrrolo(2,3-b)indoles,a process for their preparation and their use as medicaments - Google Patents

1,2,3,3a,8,8a-hexahydro-3a,8(and 1,3a,8)-di-(and tri)methylpyrrolo(2,3-b)indoles,a process for their preparation and their use as medicaments

Info

Publication number: IL83190A0
Authority: IL; Israel
Prior art keywords: loweralkyl; methyl; hydrogen; arylloweralkyl; heteroarylloweralkyl
Prior art date: 1986-07-16

Application number

IL83190A

Other languages

English (en)

Original Assignee

Hoechst Roussel Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-07-16

Filing date

1987-07-14

Publication date

1987-12-31

1987-07-14 Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma

1987-12-31 Publication of IL83190A0 publication Critical patent/IL83190A0/xx

Links

239000003814 drug Substances 0.000 title 1
150000002475 indoles Chemical class 0.000 title 1
-1 arylloweralkyl Chemical group 0.000 abstract 5
229910052739 hydrogen Inorganic materials 0.000 abstract 4
239000001257 hydrogen Substances 0.000 abstract 4
150000002431 hydrogen Chemical group 0.000 abstract 3
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 3
125000003118 aryl group Chemical group 0.000 abstract 2
125000001072 heteroaryl group Chemical group 0.000 abstract 2
229910052760 oxygen Inorganic materials 0.000 abstract 2
229910052717 sulfur Inorganic materials 0.000 abstract 2
125000004214 1-pyrrolidinyl group Chemical group [H]C1([H])N(*)C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
239000000730 antalgic agent Substances 0.000 abstract 1
125000004658 aryl carbonyl amino group Chemical group 0.000 abstract 1
150000001602 bicycloalkyls Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000000392 cycloalkenyl group Chemical group 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
125000004981 cycloalkylmethyl group Chemical group 0.000 abstract 1
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
230000006883 memory enhancing effect Effects 0.000 abstract 1
125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
125000000587 piperidin-1-yl group Chemical group [H]C1([H])N(*)C([H])([H])C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

IL83190A 1986-07-16 1987-07-14 1,2,3,3a,8,8a-hexahydro-3a,8(and 1,3a,8)-di-(and tri)methylpyrrolo(2,3-b)indoles,a process for their preparation and their use as medicaments IL83190A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US88599186A	1986-07-16	1986-07-16
US07/049,894 US4791107A (en)	1986-07-16	1987-05-15	Memory enhancing and analgesic 1,2,3,3A,8,8A-hexahydro-3A,8 (and) 1,3A,8)-di(and tri)methylpyrrolo(2,3-B)indoles, compositions and use

Publications (1)

Publication Number	Publication Date
IL83190A0 true IL83190A0 (en)	1987-12-31

Family

ID=26727666

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL83190A IL83190A0 (en)	1986-07-16	1987-07-14	1,2,3,3a,8,8a-hexahydro-3a,8(and 1,3a,8)-di-(and tri)methylpyrrolo(2,3-b)indoles,a process for their preparation and their use as medicaments

Country Status (15)

Country	Link
US (9)	US4791107A (de)
EP (1)	EP0253372B1 (de)
JP (1)	JP2716099B2 (de)
KR (1)	KR960003614B1 (de)
AT (1)	ATE112278T1 (de)
AU (1)	AU612583B2 (de)
CA (1)	CA1307788C (de)
DE (1)	DE3750596T2 (de)
DK (1)	DK367987A (de)
ES (1)	ES2060585T3 (de)
HU (1)	HU206717B (de)
IE (1)	IE64429B1 (de)
IL (1)	IL83190A0 (de)
NZ (1)	NZ221060A (de)
PT (1)	PT85334B (de)

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1987
- 1987-05-15 US US07/049,894 patent/US4791107A/en not_active Expired - Lifetime
- 1987-07-14 IL IL83190A patent/IL83190A0/xx unknown
- 1987-07-14 HU HU873208A patent/HU206717B/hu not_active IP Right Cessation
- 1987-07-14 NZ NZ221060A patent/NZ221060A/en unknown
- 1987-07-15 CA CA000542153A patent/CA1307788C/en not_active Expired - Fee Related
- 1987-07-15 PT PT85334A patent/PT85334B/pt not_active IP Right Cessation
- 1987-07-15 AT AT87110184T patent/ATE112278T1/de not_active IP Right Cessation
- 1987-07-15 EP EP87110184A patent/EP0253372B1/de not_active Expired - Lifetime
- 1987-07-15 DK DK367987A patent/DK367987A/da not_active Application Discontinuation
- 1987-07-15 ES ES87110184T patent/ES2060585T3/es not_active Expired - Lifetime
- 1987-07-15 DE DE3750596T patent/DE3750596T2/de not_active Expired - Fee Related
- 1987-07-15 IE IE191187A patent/IE64429B1/en not_active IP Right Cessation
- 1987-07-15 KR KR1019870007631A patent/KR960003614B1/ko not_active Expired - Fee Related
- 1987-07-15 AU AU75668/87A patent/AU612583B2/en not_active Ceased
- 1987-07-15 JP JP62175005A patent/JP2716099B2/ja not_active Expired - Fee Related
1992
- 1992-10-16 US US07/962,080 patent/US5663190A/en not_active Expired - Fee Related
- 1992-10-16 US US07/962,079 patent/US5547977A/en not_active Expired - Fee Related
- 1992-10-28 US US07/967,534 patent/US5541216A/en not_active Expired - Fee Related
1995
- 1995-06-06 US US08/466,013 patent/US5639892A/en not_active Expired - Fee Related
- 1995-06-07 US US08/479,197 patent/US5621114A/en not_active Expired - Fee Related
- 1995-06-07 US US08/483,696 patent/US5550253A/en not_active Expired - Fee Related
- 1995-06-07 US US08/483,700 patent/US5550254A/en not_active Expired - Fee Related
- 1995-06-07 US US08/486,256 patent/US5541340A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
HU206717B (en)	1992-12-28
NZ221060A (en)	1990-11-27
US5547977A (en)	1996-08-20
PT85334A (en)	1987-08-01
KR960003614B1 (ko)	1996-03-20
US5550254A (en)	1996-08-27
US4791107A (en)	1988-12-13
DE3750596D1 (de)	1994-11-03
EP0253372A3 (en)	1989-11-08
US5663190A (en)	1997-09-02
US5541340A (en)	1996-07-30
DE3750596T2 (de)	1995-03-23
DK367987D0 (da)	1987-07-15
AU7566887A (en)	1988-01-21
ES2060585T3 (es)	1994-12-01
US5550253A (en)	1996-08-27
US5639892A (en)	1997-06-17
AU612583B2 (en)	1991-07-18
IE64429B1 (en)	1995-08-09
US5621114A (en)	1997-04-15
IE871911L (en)	1988-01-16
JPS6323881A (ja)	1988-02-01
JP2716099B2 (ja)	1998-02-18
EP0253372A2 (de)	1988-01-20
EP0253372B1 (de)	1994-09-28
HUT47275A (en)	1989-02-28
DK367987A (da)	1988-01-17
PT85334B (pt)	1990-04-30
KR880001656A (ko)	1988-04-25
US5541216A (en)	1996-07-30
CA1307788C (en)	1992-09-22
ATE112278T1 (de)	1994-10-15

Publication	Publication Date	Title
IL83190A0 (en)	1987-12-31	1,2,3,3a,8,8a-hexahydro-3a,8(and 1,3a,8)-di-(and tri)methylpyrrolo(2,3-b)indoles,a process for their preparation and their use as medicaments
HU906494D0 (en)	1991-04-29	Process for producing substituted 1,2,3-triazole derivatives and pharmaceutical preparatives containing these compounds
PH31453A (en)	1998-11-03	7-(2-Aminoethyl)- benzothiazolones.
NZ232283A (en)	1991-08-27	Substituted imidazo(1,2-b)pyridazine derivatives; pharmaceutical compositions and preparatory processes
IL96498A0 (en)	1991-08-16	Aminocarbonylcarbamates related to physostigmine,a process for their preparation and their use as medicaments
AU630575B2 (en)	1992-10-29	Benzodiazepine derivatives
HUT49581A (en)	1989-10-30	Process for producing imidazole derivatives and pharmaceutical compositions comprising same
DK283984D0 (da)	1984-06-08	Benzodiazepinderivater og fremgangsmaade til fremstilling deraf
HUT51271A (en)	1990-04-28	Process for producing 1,2-benzisoxazole and 1,2-benzisothiazole derivatives and pharmaceutical compositions comprising such compounds
ATE86993T1 (de)	1993-04-15	Heterotetracyclische laktamderivate, verfahren zu ihrer herstellung und pharmazeutische zubereitungen, die sie enthalten.
ATE101610T1 (de)	1994-03-15	Indol-derivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate.
GR3031538T3 (en)	2000-01-31	Pyrido[3,4-b]pyrrolo[1,2-e][1,4,5]oxadiazepines and related analogs, a process for their preparation and their use as medicaments
EP0167922A3 (en)	1987-01-21	Pyrrolo û1,2-b¨ û1,2,5¨ triazepines, a process and intermediates for their preparation and their use as medicaments
AU585418B2 (en)	1989-06-15	6H-isoxazolo`` 3,4-d`` pyrazolo`` 3,4-b`` pyridines,a process for their preparation and their use as medicaments