IL87724A - Ophthalmic compositions,their preparation and use - Google Patents

Ophthalmic compositions,their preparation and use

Info

Publication number: IL87724A
Authority: IL; Israel
Prior art keywords: preparation; caused; drug; ophthalmic compositions; preservative
Prior art date: 1987-09-11

Application number

IL87724A

Other languages

English (en)

Other versions

IL87724A0 (en

Original Assignee

Syntex Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-09-11

Filing date

1988-09-09

Publication date

1992-01-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22256043&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL87724(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1988-09-09 Application filed by Syntex Inc filed Critical Syntex Inc

1989-02-28 Publication of IL87724A0 publication Critical patent/IL87724A0/xx

1992-01-15 Publication of IL87724A publication Critical patent/IL87724A/xx

Links

239000000203 mixture Substances 0.000 title abstract 3
239000003814 drug Substances 0.000 abstract 2
229940079593 drug Drugs 0.000 abstract 2
238000009472 formulation Methods 0.000 abstract 2
239000003755 preservative agent Substances 0.000 abstract 2
230000002335 preservative effect Effects 0.000 abstract 2
206010010741 Conjunctivitis Diseases 0.000 abstract 1
206010058202 Cystoid macular oedema Diseases 0.000 abstract 1
206010012689 Diabetic retinopathy Diseases 0.000 abstract 1
208000020564 Eye injury Diseases 0.000 abstract 1
208000010412 Glaucoma Diseases 0.000 abstract 1
208000001344 Macular Edema Diseases 0.000 abstract 1
206010046851 Uveitis Diseases 0.000 abstract 1
239000008135 aqueous vehicle Substances 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
201000010206 cystoid macular edema Diseases 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
230000004054 inflammatory process Effects 0.000 abstract 1
208000014674 injury Diseases 0.000 abstract 1
239000000041 non-steroidal anti-inflammatory agent Substances 0.000 abstract 1
229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 abstract 1
239000002736 nonionic surfactant Substances 0.000 abstract 1
125000001453 quaternary ammonium group Chemical group 0.000 abstract 1
238000001356 surgical procedure Methods 0.000 abstract 1
230000008733 trauma Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Ophthalmology & Optometry (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Molecular Biology (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
Detergent Compositions (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

IL87724A 1987-09-11 1988-09-09 Ophthalmic compositions,their preparation and use IL87724A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US9617387A	1987-09-11	1987-09-11

Publications (2)

Publication Number	Publication Date
IL87724A0 IL87724A0 (en)	1989-02-28
IL87724A true IL87724A (en)	1992-01-15

Family

ID=22256043

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL87724A IL87724A (en)	1987-09-11	1988-09-09	Ophthalmic compositions,their preparation and use

Country Status (17)

Country	Link
EP (1)	EP0306984B1 (de)
JP (1)	JPH0696542B2 (de)
KR (1)	KR950013754B1 (de)
AT (1)	ATE74750T1 (de)
AU (1)	AU626798B2 (de)
CA (1)	CA1328614C (de)
DE (1)	DE3870111D1 (de)
DK (1)	DK174702B1 (de)
FI (1)	FI94924C (de)
HK (1)	HK27894A (de)
HU (2)	HU199072B (de)
IE (1)	IE60717B1 (de)
IL (1)	IL87724A (de)
NO (1)	NO175404C (de)
NZ (1)	NZ226100A (de)
PH (1)	PH25422A (de)
ZA (1)	ZA886757B (de)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5414011A (en) *	1987-09-11	1995-05-09	Syntex (U.S.A.) Inc.	Preservative system for ophthalmic formulations
ATE103182T1 (de) *	1989-09-21	1994-04-15	Ciba Vision Ag	Antimikrobielle zusammensetzungen.
IL95942A0 (en) *	1989-10-13	1991-07-18	Syntex Inc	Collagen-containing ophthalmic formulation
US5464609A (en) *	1990-03-16	1995-11-07	The Procter & Gamble Company	Use of ketorolac for treatment of oral diseases and conditions
ATE137967T1 (de) *	1990-03-16	1996-06-15	Procter & Gamble	Verwendung von ketorolac zur behandlung von periodontitis
AU653768B2 (en) *	1990-12-27	1994-10-13	Advanced Medical Optics, Inc.	Method and composition for disinfecting contact lenses
US5227152A (en) *	1991-04-09	1993-07-13	Merck Frosst Canada, Inc.	Radiopharmaceutical bacteriostats
US5306482A (en) *	1991-04-09	1994-04-26	Merck Frosst Canada, Inc.	Radiopharmaceutical bacteriostats
US5093105A (en) *	1991-04-09	1992-03-03	Merck Frosst Canada, Inc.	Radiopharmaceutical bacteriostats
JPH09506620A (ja) *	1993-12-17	1997-06-30	アルコン・ラボラトリーズ，インコーポレイテッド	非ステロイド抗炎症剤を含有する改良された眼内洗浄溶液
US5474985A (en) *	1993-12-22	1995-12-12	The Regents Of The University Of California	Preventing and treating elevated intraocular pressure associated with administered or endogenous steroids using non-steroidal cyclooxygenase inhibitors
ES2079320B1 (es) *	1994-05-17	1996-10-16	Cusi Lab	Disolucion oftalmica a base de un diclofenaco y tobramicina y sus aplicaciones.
WO1995033456A2 (en) *	1994-06-07	1995-12-14	Telor Ophthalmic Pharmaceuticals, Inc.	Reducing intraocular pressure using aryloxy- and aryl-acetic acids
AU3609795A (en) *	1994-10-10	1996-05-02	Novartis Ag	Ophthalmic and aural compositions containing diclofenac potassium
US5603929A (en) *	1994-11-16	1997-02-18	Alcon Laboratories, Inc.	Preserved ophthalmic drug compositions containing polymeric quaternary ammonium compounds
ATE215821T1 (de) *	1995-01-20	2002-04-15	Wakamoto Pharma Co Ltd	Entzündungshemmende augentropfen
US5674888A (en) *	1995-06-07	1997-10-07	University Of California	Method for the treatment of a trabecular meshwork whose cells are subject to inhibition of cell division
US5599535A (en) *	1995-06-07	1997-02-04	Regents Of The University Of California	Methods for the cyto-protection of the trabecular meshwork
TW434023B (en) *	1995-09-18	2001-05-16	Novartis Ag	Preserved ophthalmic composition
JPH09278653A (ja) *	1996-04-05	1997-10-28	Santen Pharmaceut Co Ltd	網膜疾患治療剤
MX9701946A (es) *	1997-03-14	1998-04-30	Arturo Jimenez Bayardo	Solucion oftalmica transportadora.
DE19729879C2 (de) *	1997-07-11	1999-07-08	Mann Gerhard Chem Pharm Fab	Lagerstabile ophthalmische Zusammensetzungen, umfassend Diclofenac und Ofloxacin
JP2006111636A (ja) *	1997-12-26	2006-04-27	Astellas Pharma Inc	徐放性医薬組成物
DE60039043D1 (de) *	1999-03-02	2008-07-10	Vitreo Retinal Technologies In	Mittel für intravitreale verabreichung zur behandlung oder vorbeugung von augenerkrankungen
DE19918324A1 (de) *	1999-04-22	2000-10-26	Mann Gerhard Chem Pharm Fab	Pharmazeutische Zusammensetzung wirksam gegen durch Bakterien, Viren, Pilze, Hefen und Protozoen verursachte Krankheitszustände
US20020035107A1 (en)	2000-06-20	2002-03-21	Stefan Henke	Highly concentrated stable meloxicam solutions
DE10161077A1 (de)	2001-12-12	2003-06-18	Boehringer Ingelheim Vetmed	Hochkonzentrierte stabile Meloxicamlösungen zur nadellosen Injektion
US8992980B2 (en)	2002-10-25	2015-03-31	Boehringer Ingelheim Vetmedica Gmbh	Water-soluble meloxicam granules
WO2004064828A1 (ja)	2003-01-21	2004-08-05	Senju Pharmaceutical Co., Ltd.	２−アミノ−３−(４−ブロモベンゾイル)フェニル酢酸含有水性液剤
US8008338B2 (en)	2003-06-03	2011-08-30	Allergan, Inc.	Ketorolac tromethamine compositions for treating or preventing ocular pain
EP1654002B2 (de)	2003-08-07	2014-01-29	Allergan, Inc.	Zusammensetzungen zur abgabe von therapeutika in die augen
EP1568369A1 (de)	2004-02-23	2005-08-31	Boehringer Ingelheim Vetmedica Gmbh	Verwendung von Meloxicam zur Behandlung von Atemwegserkrankungen bei Schweinen
WO2005102303A2 (en) *	2004-04-21	2005-11-03	Advanced Ocular Systems Limited	Antiprostaglandins for the treatment of ocular pathologies
US9161905B2 (en) *	2005-01-12	2015-10-20	Ocular Research Of Boston, Inc.	Dry eye treatment
US9192571B2 (en)	2008-03-03	2015-11-24	Allergan, Inc.	Ketorolac tromethamine compositions for treating or preventing ocular pain
US9101529B2 (en)	2009-10-12	2015-08-11	Boehringer Ingelheim Vetmedica Gmbh	Containers for compositions comprising meloxicam
WO2011107150A1 (en)	2010-03-03	2011-09-09	Boehringer Ingelheim Vetmedica Gmbh	Use of meloxicam for the long-term treatment of musculoskeletal disorders in cats
US9795568B2 (en)	2010-05-05	2017-10-24	Boehringer Ingelheim Vetmedica Gmbh	Low concentration meloxicam tablets
JP2013082682A (ja) *	2011-09-29	2013-05-09	Senju Pharmaceut Co Ltd	亜塩素酸塩を含有する水性製剤
CN110448530A (zh) *	2018-05-07	2019-11-15	北京蓝丹医药科技有限公司	一种氟比洛芬酯注射液

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4087538A (en) *	1976-09-09	1978-05-02	Merck & Co., Inc.	Ophthalmic suspensions
DE3026402A1 (de) *	1980-07-11	1982-02-04	Syntex Corp., Palo Alto, Calif.	Die verwendung analgetischer und nicht-hormonaler, entzuendungshemmender mittel bei der behandlung von mikrovaskulaeren erkrankungen
AU573321B2 (en) *	1984-03-14	1988-06-02	Jerome Corbiere	Process for solubilizing active principles and pharmaceuticalcompositions thus obtained

1988
- 1988-09-09 JP JP63227343A patent/JPH0696542B2/ja not_active Expired - Lifetime
- 1988-09-09 KR KR1019880011664A patent/KR950013754B1/ko not_active Expired - Lifetime
- 1988-09-09 AT AT88114804T patent/ATE74750T1/de not_active IP Right Cessation
- 1988-09-09 DE DE8888114804T patent/DE3870111D1/de not_active Expired - Lifetime
- 1988-09-09 NZ NZ226100A patent/NZ226100A/en unknown
- 1988-09-09 EP EP88114804A patent/EP0306984B1/de not_active Expired - Lifetime
- 1988-09-09 NO NO884020A patent/NO175404C/no not_active IP Right Cessation
- 1988-09-09 ZA ZA886757A patent/ZA886757B/xx unknown
- 1988-09-09 FI FI884160A patent/FI94924C/fi not_active IP Right Cessation
- 1988-09-09 AU AU22042/88A patent/AU626798B2/en not_active Expired
- 1988-09-09 CA CA000576880A patent/CA1328614C/en not_active Expired - Lifetime
- 1988-09-09 IL IL87724A patent/IL87724A/xx not_active IP Right Cessation
- 1988-09-09 PH PH37525A patent/PH25422A/en unknown
- 1988-09-09 DK DK198805056A patent/DK174702B1/da not_active IP Right Cessation
- 1988-09-09 IE IE274088A patent/IE60717B1/en not_active IP Right Cessation
- 1988-09-09 HU HU884648A patent/HU199072B/hu unknown
1994
- 1994-03-24 HK HK278/94A patent/HK27894A/en not_active IP Right Cessation
- 1994-07-01 HU HU94P/P00006P patent/HU210610A9/hu unknown

Also Published As

Publication number	Publication date
EP0306984B1 (de)	1992-04-15
JPH01104023A (ja)	1989-04-21
IE882740L (en)	1989-03-11
HU210610A9 (en)	1995-05-29
AU2204288A (en)	1989-03-16
EP0306984A1 (de)	1989-03-15
HK27894A (en)	1994-03-31
ZA886757B (en)	1990-05-30
IL87724A0 (en)	1989-02-28
DK174702B1 (da)	2003-09-29
NO175404C (no)	1994-10-12
CA1328614C (en)	1994-04-19
NZ226100A (en)	1990-12-21
NO884020D0 (no)	1988-09-09
IE60717B1 (en)	1994-08-10
FI94924C (fi)	1995-11-27
AU626798B2 (en)	1992-08-13
DK505688D0 (da)	1988-09-09
DE3870111D1 (de)	1992-05-21
FI884160A0 (fi)	1988-09-09
KR950013754B1 (ko)	1995-11-15
KR890004691A (ko)	1989-05-09
JPH0696542B2 (ja)	1994-11-30
ATE74750T1 (de)	1992-05-15
FI94924B (fi)	1995-08-15
NO884020L (no)	1989-03-13
HUT47839A (en)	1989-04-28
HU199072B (en)	1990-01-29
FI884160L (fi)	1989-03-12
DK505688A (da)	1989-03-12
NO175404B (no)	1994-07-04
PH25422A (en)	1991-07-01

Legal Events

Date	Code	Title
1999-01-26	KB	Patent renewed
2002-11-10	KB	Patent renewed
2006-10-30	KB	Patent renewed
2009-02-11	EXP	Patent expired
2010-04-14	EXP	Patent expired

Publication	Publication Date	Title
IL87724A0 (en)	1989-02-28	Ophthalmic compositions,their preparation and use
CA2013188A1 (en)	1990-09-28	Preservative system for ophthalmic formulations
KR100260061B1 (en)	2000-07-01	Vitamin e drop
DE69333927D1 (de)	2006-01-12	Agglomerierte hydrophile Komplexe mit mehrphasigen Abgabeeigenschaften
WO2001030337A3 (en)	2002-01-24	Ophthalmic formulation of dopamine antagonists
Edelhauser et al.	1982	Corneal edema and the intraocular use of epinephrine
EP1378247A4 (de)	2007-07-25	Wirkstoffe zur behandlung von sehfunktionsstörungen
LV10688A (lv)	1995-06-20	Pretalergisks sastavs oftalmologijai vai deguna slimibam
DK0394211T3 (da)	1993-08-16	Forbedrede præparater med forøget vandopløselighed
DE3152759T1 (de)	1983-06-16	Flexible intraokulare linse
ES2187845T3 (es)	2003-06-16	Solucion oftalmica vehiculo.
EP1110554A4 (de)	2002-02-06	Medizinische zusammensetzungen zur behandlung von augenerkrankungen
IE811654L (en)	1982-02-01	Ophthalmic composition
DE69737421T2 (de)	2007-11-08	Intraokulare linse mit abzugebendem medikament
DE69013431D1 (de)	1994-11-24	Anthocyanidine zur Behandlung von Augenkrankheiten.
Millichamp et al.	1991	Comparison of flunixin meglumine and flurbiprofen for control of ocular irritative response in dogs
SU1357021A1 (ru)	1987-12-07	Средство, уменьшающее проницаемость капилл ров, снижающее агрегацию тромбоцитов, дл лечени внутриглазных кровоизли ний
Meyers	1986	Endophthalmitis.
EIM et al.	1992	EVALUATION OF GENTA MICIN SULFATE IN AQUEOUS HUMOR OF DONKEYS FOLLOWING ITS ADMINISTRATION
KAUFMAN	1975	Systemic therapy of ocular herpes
DE3102593A1 (de)	1982-09-02	Arzneimittelzubereitung zur anwendung am auge
Kellner et al.	1983	Primary eye irritation of 1-acetyloctahydro-3, 5, 7-trinitro-1, 3, 5, 6-tetrazocine.
Gelatt	1981	Multifocal ocular histoplasmosis in a dog and cat: by RM Gwin, Torrence A. Makley, Jr., Milton Wyman, and Kathryn Werling. J Am Vet Med Assoc 176: 638–642, 1980
IT1241928B (it)	1994-02-01	Composizione oftalmica per l'uso nel mantenimento della midriasi oculare
MX9605633A (es)	1998-05-31	Composicion farmaceutica, metodo y dispositivo para prevenir o tratar resequedad de los ojos o enfermedad ocasionada por la misma.