IL95046A - Substituted 2-imidazolines and pharmaceutical compositions containing them. - Google Patents

Substituted 2-imidazolines and pharmaceutical compositions containing them.

Info

Publication number
IL95046A
IL95046A IL9504690A IL9504690A IL95046A IL 95046 A IL95046 A IL 95046A IL 9504690 A IL9504690 A IL 9504690A IL 9504690 A IL9504690 A IL 9504690A IL 95046 A IL95046 A IL 95046A
Authority
IL
Israel
Prior art keywords
chloro
fluoro
pyridyl
bromo
hydrogen
Prior art date
Application number
IL9504690A
Other languages
English (en)
Other versions
IL95046A0 (en
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of IL95046A0 publication Critical patent/IL95046A0/xx
Publication of IL95046A publication Critical patent/IL95046A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Endocrinology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nonmetallic Welding Materials (AREA)
  • External Artificial Organs (AREA)
  • Lubricants (AREA)
  • Fertilizers (AREA)
IL9504690A 1989-07-12 1990-07-11 Substituted 2-imidazolines and pharmaceutical compositions containing them. IL95046A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK344489A DK344489D0 (da) 1989-07-12 1989-07-12 Substituerede 2-imidazoliner og fremstilling og anvendelse deraf

Publications (2)

Publication Number Publication Date
IL95046A0 IL95046A0 (en) 1991-06-10
IL95046A true IL95046A (en) 1995-03-15

Family

ID=8122944

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9504690A IL95046A (en) 1989-07-12 1990-07-11 Substituted 2-imidazolines and pharmaceutical compositions containing them.

Country Status (22)

Country Link
US (1) US5262430A (de)
EP (1) EP0482108B1 (de)
JP (1) JPH04506968A (de)
KR (1) KR927003578A (de)
CN (1) CN1049343A (de)
AT (1) ATE135703T1 (de)
AU (1) AU637393B2 (de)
CA (1) CA2064095A1 (de)
DD (1) DD296489A5 (de)
DE (1) DE69026087T2 (de)
DK (2) DK344489D0 (de)
ES (1) ES2086409T3 (de)
FI (1) FI920118A0 (de)
GR (1) GR1000716B (de)
IE (1) IE74210B1 (de)
IL (1) IL95046A (de)
NO (1) NO920143L (de)
NZ (1) NZ234451A (de)
PT (1) PT94685B (de)
WO (1) WO1991000862A1 (de)
YU (1) YU136390A (de)
ZA (1) ZA905422B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4201709A1 (de) * 1992-01-23 1993-07-29 Bayer Ag (alpha)-aryl-(alpha)-hydroxy-ss-imidazolinyl-propionsaeureamide
US5750543A (en) * 1996-02-01 1998-05-12 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
US6410562B1 (en) 1998-12-18 2002-06-25 Eli Lilly And Company Hypoglycemic imidazoline compounds
US20090162342A1 (en) * 2001-06-07 2009-06-25 Sanomune Inc. Therapeutic uses of glandular kallikrein
BRPI0511722A (pt) * 2004-06-01 2008-01-08 Hoffmann La Roche 3-amino-1-arilpropilindóis como inibidores da recaptação de monoamina
WO2013173923A1 (en) 2012-05-25 2013-11-28 Diamedica, Inc. Formulations of human tissue kallikrein-1 for parenteral delivery and related methods
PT2854841T (pt) 2012-06-04 2017-05-15 Diamedica Inc Isoformas de glicosilação da calicreína 1 em tecido humano
US11857608B2 (en) 2017-03-09 2024-01-02 Diamedica Inc. Dosage forms of tissue kallikrein 1

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5936885B2 (ja) * 1976-06-24 1984-09-06 第一製薬株式会社 糖尿病治療剤
ZW13782A1 (en) * 1981-07-28 1982-10-06 Reckitt & Colmann Prod Ltd Imidazoline derivatives
GB2167408B (en) * 1984-11-23 1988-05-25 Farmos Oy Substituted imidazole derivatives and their preparation and use

Also Published As

Publication number Publication date
AU6164490A (en) 1991-02-06
FI920118A7 (fi) 1992-01-10
EP0482108A1 (de) 1992-04-29
ES2086409T3 (es) 1996-07-01
CN1049343A (zh) 1991-02-20
CA2064095A1 (en) 1991-01-13
DD296489A5 (de) 1991-12-05
IE74210B1 (en) 1997-07-16
DE69026087T2 (de) 1996-08-29
NO920143D0 (no) 1992-01-10
IL95046A0 (en) 1991-06-10
YU136390A (sh) 1993-10-20
IE902546A1 (en) 1991-02-27
JPH04506968A (ja) 1992-12-03
AU637393B2 (en) 1993-05-27
GR900100535A (en) 1991-12-10
ATE135703T1 (de) 1996-04-15
US5262430A (en) 1993-11-16
PT94685A (pt) 1991-03-20
NZ234451A (en) 1991-08-27
PT94685B (pt) 1997-04-30
KR927003578A (ko) 1992-12-18
EP0482108B1 (de) 1996-03-20
FI920118A0 (fi) 1992-01-10
GR1000716B (el) 1992-11-23
WO1991000862A1 (en) 1991-01-24
DK0482108T3 (da) 1996-07-22
DK344489D0 (da) 1989-07-12
DE69026087D1 (de) 1996-04-25
NO920143L (no) 1992-03-04
ZA905422B (en) 1991-03-27

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees