IN2012DN00338A - - Google Patents

Download PDF

Info

Publication number
IN2012DN00338A
IN2012DN00338A IN338DEN2012A IN2012DN00338A IN 2012DN00338 A IN2012DN00338 A IN 2012DN00338A IN 338DEN2012 A IN338DEN2012 A IN 338DEN2012A IN 2012DN00338 A IN2012DN00338 A IN 2012DN00338A
Authority
IN
India
Prior art keywords
methods
relates
present
region containing
containing protein
Prior art date
Application number
Other languages
English (en)
Inventor
Soice Neil
Hubbard Dana
Zhang Yu
Harmzik James
Original Assignee
Millipore Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millipore Corp filed Critical Millipore Corp
Publication of IN2012DN00338A publication Critical patent/IN2012DN00338A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/22Affinity chromatography or related techniques based upon selective absorption processes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/36Extraction; Separation; Purification by a combination of two or more processes of different types
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/18Ion-exchange chromatography
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
IN338DEN2012 2009-08-07 2010-08-05 IN2012DN00338A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27370909P 2009-08-07 2009-08-07
PCT/US2010/044539 WO2011017514A1 (en) 2009-08-07 2010-08-05 Methods for purifying a target protein from one or more impurities in a sample

Publications (1)

Publication Number Publication Date
IN2012DN00338A true IN2012DN00338A (es) 2015-05-22

Family

ID=43544660

Family Applications (1)

Application Number Title Priority Date Filing Date
IN338DEN2012 IN2012DN00338A (es) 2009-08-07 2010-08-05

Country Status (9)

Country Link
US (1) US8536316B2 (es)
EP (1) EP2462157B1 (es)
JP (2) JP5791602B2 (es)
KR (1) KR101415660B1 (es)
CN (2) CN107188960A (es)
ES (1) ES2817802T3 (es)
IN (1) IN2012DN00338A (es)
SG (1) SG177577A1 (es)
WO (1) WO2011017514A1 (es)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3237179B2 (ja) 1992-03-18 2001-12-10 栗田工業株式会社 排超純水中の過酸化水素の除去方法
US20130178608A1 (en) * 2009-12-29 2013-07-11 Samir Kulkarni Protein purification by ion exchange
EP4492053A3 (en) 2010-05-25 2025-03-19 F. Hoffmann-La Roche AG Methods of purifying polypeptides
US9029517B2 (en) 2010-07-30 2015-05-12 Emd Millipore Corporation Chromatography media and method
CA2777978A1 (en) 2011-05-27 2012-11-27 Abbott Biotherapeutics Corp. Dac hyp compositions and methods
KR20140033126A (ko) 2011-06-16 2014-03-17 디에스엠 아이피 어셋츠 비.브이. 단일 유닛 크로마토그래피 항체 정제
JP6280499B2 (ja) * 2011-07-08 2018-02-14 メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. Fc融合タンパク質の精製方法
EP2734537B1 (en) * 2011-07-20 2022-12-21 Zepteon, Incorporated Polypeptide separation methods
CA2843315A1 (en) * 2011-08-01 2013-02-07 Avaxia Biologics, Inc. Bovine polyclonal antibody specific for human tnf
US9096648B2 (en) * 2011-08-19 2015-08-04 Emd Millipore Corporation Methods of reducing level of one or more impurities in a sample during protein purification
US20140228548A1 (en) * 2011-09-01 2014-08-14 Human Genome Sciences Viral clearance methods
EP2578286A1 (en) 2011-10-04 2013-04-10 Merck Patent GmbH Method and apparatus for chromatographic purification
EP3527274B1 (en) * 2011-11-02 2025-12-24 F. Hoffmann-La Roche AG Overload and elute chromatography
WO2013075740A1 (en) 2011-11-23 2013-05-30 Sanofi Antibody purification method
CN102492040B (zh) * 2011-12-29 2014-06-25 嘉和生物药业有限公司 一种抗her2或/和抗her3抗体蛋白的纯化方法
SG10201701224UA (en) * 2012-03-12 2017-04-27 Merck Patent Gmbh Removal of protein aggregates from biopharmaceutical preparations in a flowthrough mode
EP2682168A1 (en) 2012-07-02 2014-01-08 Millipore Corporation Purification of biological molecules
EP2889617B1 (en) * 2012-08-27 2017-10-11 Asahi Kasei Medical Co., Ltd. Antibody purification method by means of temperature-responsive chromatography
AU2013315750B9 (en) 2012-09-11 2018-11-15 Coherus Biosciences, Inc. Correctly folded etanercept in high purity and excellent yield
IN2015DN02055A (es) 2012-09-17 2015-08-14 Grace W R & Co
US10421795B2 (en) 2012-12-17 2019-09-24 Merck Sharp & Dohme Corp. Process for purifying insulin and analogues thereof
JP2016507671A (ja) 2013-02-14 2016-03-10 ナノパレイル,エルエルシー 電界紡糸ナノファイバーのハイブリッドフェルト
TWI631132B (zh) * 2013-05-06 2018-08-01 賽諾菲公司 用於純化抗體之連續多步驟方法
JP6602765B2 (ja) * 2013-09-05 2019-11-06 ジェネンテック, インコーポレイテッド クロマトグラフィー再使用のための方法
JPWO2015041218A1 (ja) * 2013-09-17 2017-03-02 株式会社カネカ 新規抗体精製方法及びそれから得られる抗体(NovelAntibodyPurificationMethodandAntibodyobtainedtherefrom)、並びに陽イオン交換基を用いた新規抗体精製法及びそれから得られる抗体(NovelAntibodyPurificationmethodusingCationExchangerandAntibodyobtainedtherefrom)
WO2015088677A1 (en) 2013-12-12 2015-06-18 Emd Millipore Corporation Protein separations using an acrylamide containing filter
CN105980847B (zh) * 2014-02-14 2018-12-04 通用电气健康护理生物科学股份公司 自动多步纯化系统
SI3116891T1 (sl) 2014-03-10 2020-07-31 Richter Gedeon Nyrt. Čiščenje imunoglobulina z uporabo predčistilnih stopenj
CN104826617B (zh) * 2014-03-25 2017-06-13 西北大学 一种用于蛋白质分离的wax/hic双功能混合模式色谱固定相及其制备方法
EP3137209B1 (en) 2014-05-02 2022-10-05 W.R. Grace & CO. - CONN. Functionalized support material and methods of making and using functionalized support material
EP3145951A1 (en) * 2014-06-24 2017-03-29 InSight Biopharmaceuticals Ltd. Methods of purifying antibodies
DE102014010353B4 (de) 2014-07-10 2024-09-12 Sartorius Stedim Biotech Gmbh Vorrichtung, Verwendung dieser Vorrichtung und Verfahren für die Stofftrennung mit verbesserter Ausnutzung der Kapazität chromatographischer Medien
US20170298091A1 (en) 2014-12-08 2017-10-19 Emd Millipore Corporation Mixed Bed Ion Exchange Adsorber
SG10201911134QA (en) 2015-06-05 2020-01-30 Grace W R & Co Adsorbent bioprocessing clarification agents and methods of making and using the same
WO2017176735A1 (en) * 2016-04-05 2017-10-12 Haemonetics Corporation Methods and devices for the enrichment of immunoglobulin from blood
CN107964044B (zh) * 2016-10-19 2021-11-19 无锡科捷诺生物科技有限责任公司 从乳样中纯化抗cd20单克隆抗体的方法
WO2019183334A1 (en) 2018-03-21 2019-09-26 Waters Technologies Corporation Non-antibody high-affinity-based sample preparation, sorbents, devices and methods
EP3546475A1 (en) 2018-03-27 2019-10-02 Sanofi Full flow-through process for purifying recombinant proteins
CN113166200B (zh) * 2018-12-21 2024-03-01 上海药明生物技术有限公司 一种提高蛋白a层析法去除聚集体的方法
FR3099066B1 (fr) * 2019-07-26 2021-08-13 Novasep Process Procédé de purification d’une substance cible avec inactivation virale
TW202128264A (zh) * 2019-09-25 2021-08-01 瑞士商赫孚孟拉羅股份公司 使用經預測之溶離緩衝鹽濃度的陽離子層析法
US20220348608A1 (en) * 2019-10-04 2022-11-03 Merck Patent Gmbh Purification of proteins and viral inactivation
CN110724204B (zh) * 2019-11-18 2021-10-22 广东菲鹏制药股份有限公司 Fc融合蛋白的纯化方法
CN113845562A (zh) * 2020-06-28 2021-12-28 佛山汉腾生物科技有限公司 目的蛋白纯化方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4490937A (en) 1981-12-07 1985-01-01 Amcor Ltd. Insect electrocution device
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5256694A (en) 1984-09-22 1993-10-26 Basf Aktiengesellschaft Diarylacetylenes, their preparation and their use
US5091178A (en) 1986-02-21 1992-02-25 Oncogen Tumor therapy with biologically active anti-tumor antibodies
US6054051A (en) 1996-01-17 2000-04-25 Genentech, Inc. Tangential-flow filtration system
DK1501369T3 (en) 2002-04-26 2015-09-28 Genentech Inc Non-affinity purification of proteins
ES2626268T3 (es) * 2002-09-11 2017-07-24 Chugai Seiyaku Kabushiki Kaisha Método de purificación de proteínas
GB0304576D0 (en) 2003-02-28 2003-04-02 Lonza Biologics Plc Protein a chromatography
AU2005279347A1 (en) * 2004-08-30 2006-03-09 Lonza Biologics Plc. Affinity- plus ion exchange- chromatography for purifying antibodies
JP2010510963A (ja) * 2006-06-14 2010-04-08 グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー セラミックヒドロキシアパタイトを使用する抗体の精製方法
BRPI0716139A2 (pt) 2006-08-28 2013-09-17 Ares Trading Sa processo para purificaÇço de proteÍnas de fusço fc
US8513393B2 (en) * 2006-08-28 2013-08-20 Ares Trading S.A. Process for the purification of Fc-containing proteins
JP2010516651A (ja) * 2007-01-17 2010-05-20 メルク セローノ ソシエテ アノニム Fc含有タンパク質の精製のための方法
US9433922B2 (en) 2007-08-14 2016-09-06 Emd Millipore Corporation Media for membrane ion exchange chromatography based on polymeric primary amines, sorption device containing that media, and chromatography scheme and purification method using the same
WO2009045897A1 (en) * 2007-10-03 2009-04-09 Dyax Corp. Systems and methods for purifying proteins
EP2281000A2 (en) 2008-05-15 2011-02-09 Novo Nordisk A/S Antibody purification process
SG195577A1 (en) * 2008-10-20 2013-12-30 Abbott Lab Viral inactivation during purification of antibodies

Also Published As

Publication number Publication date
CN107188960A (zh) 2017-09-22
KR20120089432A (ko) 2012-08-10
WO2011017514A1 (en) 2011-02-10
EP2462157A4 (en) 2012-12-26
KR101415660B1 (ko) 2014-07-16
CN102574911B (zh) 2017-06-06
US20110065901A1 (en) 2011-03-17
JP6335838B2 (ja) 2018-05-30
EP2462157A1 (en) 2012-06-13
US8536316B2 (en) 2013-09-17
SG177577A1 (en) 2012-03-29
JP2015157846A (ja) 2015-09-03
ES2817802T3 (es) 2021-04-08
CN102574911A (zh) 2012-07-11
EP2462157B1 (en) 2020-06-17
JP5791602B2 (ja) 2015-10-07
JP2013501721A (ja) 2013-01-17

Similar Documents

Publication Publication Date Title
IN2012DN00801A (es)
MX2009007632A (es) Precipitacion de polielectrolito y purificacion de proteinas.
TW200801262A (en) Method for purifying silicon
MX336715B (es) Purificacion de iduronato-2-sulfatasa.
BRPI0917993A2 (pt) composições de célula-tronco mesenquimal purificada e métodos de purificação de composições de célula-tronco mesenquimal purificda.
PL2291329T3 (pl) System oczyszczania cieczy, zwłaszcza oczyszczania wody balastowej
HUE046909T2 (hu) Eljárás rekombináns ADAMTS13 és más proteinek és készítményeik tisztítására
MX2011008621A (es) Proceso para la purificacion de lipopeptidos.
EA201070987A1 (ru) Очищенные гибридные белки иммуноглобулина и способы их очищения
MX2012004110A (es) Proceso para purificar (hidro) fluoroalquenos.
EA201270616A1 (ru) Ингибиторы вируса гепатита с
GB2471806A (en) Compositions and methods for treating viral infections
WO2010151797A3 (en) Compounds for modulating rna binding proteins and uses therefor
MX342920B (es) Metodo para purificar polipeptidos o inmunoconjugados activos.
MX2012002565A (es) Purificacion de proteina mejorada a traves de una elucion de proteina a modificada.
MY188566A (en) Method to improve virus removal in protein purification
WO2011017132A3 (en) Mk2 inhibitor compositions and methods to enhance neurite outgrowth, neuroprotection, and nerve regeneration
UA108636C2 (xx) Пептид
WO2008085962A3 (en) Cell culture methods for producing recombinant proteins in the presence of reduced levels of one or more contaminants
EP2462157A4 (en) PROCESS FOR CLEANING A TARGET PROTEIN OF ONE OR MORE CONTAMINANTS IN A SAMPLE
MX2011000281A (es) Fibrinogeno recombinante.
IN2012DN01849A (es)
MX2011008179A (es) Peptidos para vacuna.
TW200738622A (en) Process for purifying (meth)acrylates
UA103197C2 (uk) Застосування ніфуртимоксу для лікування хвороб, спричинених трихомонадами