IN2012DN00338A - - Google Patents

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Publication number
IN2012DN00338A
IN2012DN00338A IN338DEN2012A IN2012DN00338A IN 2012DN00338 A IN2012DN00338 A IN 2012DN00338A IN 338DEN2012 A IN338DEN2012 A IN 338DEN2012A IN 2012DN00338 A IN2012DN00338 A IN 2012DN00338A
Authority
IN
India
Prior art keywords
methods
relates
present
region containing
containing protein
Prior art date
Application number
Other languages
English (en)
Inventor
Soice Neil
Hubbard Dana
Zhang Yu
Harmzik James
Original Assignee
Millipore Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millipore Corp filed Critical Millipore Corp
Publication of IN2012DN00338A publication Critical patent/IN2012DN00338A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
IN338DEN2012 2009-08-07 2010-08-05 IN2012DN00338A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27370909P 2009-08-07 2009-08-07
PCT/US2010/044539 WO2011017514A1 (fr) 2009-08-07 2010-08-05 Procédés de purification d’une protéine cible d’une ou plusieurs impuretés dans un échantillon

Publications (1)

Publication Number Publication Date
IN2012DN00338A true IN2012DN00338A (fr) 2015-05-22

Family

ID=43544660

Family Applications (1)

Application Number Title Priority Date Filing Date
IN338DEN2012 IN2012DN00338A (fr) 2009-08-07 2010-08-05

Country Status (9)

Country Link
US (1) US8536316B2 (fr)
EP (1) EP2462157B1 (fr)
JP (2) JP5791602B2 (fr)
KR (1) KR101415660B1 (fr)
CN (2) CN102574911B (fr)
ES (1) ES2817802T3 (fr)
IN (1) IN2012DN00338A (fr)
SG (1) SG177577A1 (fr)
WO (1) WO2011017514A1 (fr)

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WO2011090719A2 (fr) * 2009-12-29 2011-07-28 Dr. Reddy's Laboratories Ltd. Purification des protéines par échange d'ions
HRP20171095T4 (hr) 2010-05-25 2022-07-22 F. Hoffmann - La Roche Ag Postupci pročišćavanja polipeptida
WO2012015908A2 (fr) 2010-07-30 2012-02-02 Millipore Corporation Phase de chromatographie et procédé
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EP2721052A1 (fr) * 2011-06-16 2014-04-23 DSM IP Assets B.V. Purification d'anticorps par chromatographie dans une seule et même unité
JP6280499B2 (ja) * 2011-07-08 2018-02-14 メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． Ｆｃ融合タンパク質の精製方法
CN103827134A (zh) 2011-07-20 2014-05-28 泽普泰恩股份有限公司 多肽分离方法
WO2013019889A2 (fr) * 2011-08-01 2013-02-07 Avaxia Biologics, Inc. Anticorps polyclonal bovin spécifique du tnf humain
US9096648B2 (en) 2011-08-19 2015-08-04 Emd Millipore Corporation Methods of reducing level of one or more impurities in a sample during protein purification
WO2013033517A1 (fr) * 2011-09-01 2013-03-07 Human Genome Sciences, Inc. Procédés de clairance virale
EP2578286A1 (fr) * 2011-10-04 2013-04-10 Merck Patent GmbH Procédé et appareil de purification chromatographique
KR20140091721A (ko) * 2011-11-02 2014-07-22 제넨테크, 인크. 오버로드 및 용리 크로마토그래피
WO2013075740A1 (fr) 2011-11-23 2013-05-30 Sanofi Procédé de purification d'anticorps
CN102492040B (zh) * 2011-12-29 2014-06-25 嘉和生物药业有限公司 一种抗her2或/和抗her3抗体蛋白的纯化方法
SG10201701224UA (en) * 2012-03-12 2017-04-27 Merck Patent Gmbh Removal of protein aggregates from biopharmaceutical preparations in a flowthrough mode
EP2682168A1 (fr) 2012-07-02 2014-01-08 Millipore Corporation Dispositif de tirage et métier à filer
EP2889617B1 (fr) 2012-08-27 2017-10-11 Asahi Kasei Medical Co., Ltd. Procédé de purification d'anticorps au moyen d'une chromatographie sensible à la température
KR102250937B1 (ko) * 2012-09-11 2021-05-12 코히러스 바이오사이언시즈, 인코포레이티드 고순도 및 탁월한 수율의 정확하게 폴딩된 에타너셉트
MY178616A (en) 2012-09-17 2020-10-19 Grace W R & Co Chromatography media and devices
US10421795B2 (en) 2012-12-17 2019-09-24 Merck Sharp & Dohme Corp. Process for purifying insulin and analogues thereof
SI2959509T1 (sl) 2013-02-14 2018-11-30 Nanopareil, Llc Polst iz elektropredenih hibridnih nanovlaken, postopek za izdelavo le-te in postopek čiščenja biomolekul
DK2994485T3 (en) * 2013-05-06 2018-04-23 Sanofi Sa CONTINUOUS MULTIPLE STEP PROCEDURE FOR PURIFICATION OF ANTIBODIES
EP3041593B1 (fr) * 2013-09-05 2025-01-29 F. Hoffmann-La Roche AG Procédé de nettoyage d'un matériau de chromatographie en vue de sa réutilisation
KR20160054597A (ko) * 2013-09-17 2016-05-16 가부시키가이샤 가네카 신규 항체 정제 방법 및 그로부터 얻어지는 항체, 및 양이온 교환기를 사용한 신규 항체 정제법 및 그로부터 얻어지는 항체
US9951101B2 (en) 2013-12-12 2018-04-24 Emd Millipore Corporation Protein separations using an acrylamide containing filter
JP6612242B2 (ja) * 2014-02-14 2019-11-27 ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ 自動化された多段階精製システム及び多段階クロマトグラフィー精製方法
EP3116891B1 (fr) 2014-03-10 2020-02-12 Richter Gedeon Nyrt. Purification d'immunoglobuline à l'aide d'étapes de pré-nettoyage
CN104826617B (zh) * 2014-03-25 2017-06-13 西北大学 一种用于蛋白质分离的wax/hic双功能混合模式色谱固定相及其制备方法
JP6914189B2 (ja) 2014-05-02 2021-08-04 ダブリュー・アール・グレース・アンド・カンパニー−コーンＷ Ｒ Ｇｒａｃｅ ＆ Ｃｏ−Ｃｏｎｎ 官能化担体材料並びに官能化担体材料を作製及び使用する方法
WO2015198320A1 (fr) * 2014-06-24 2015-12-30 Insight Biopharmaceuticals Ltd. Procédés de purification d'anticorps
DE102014010353B4 (de) 2014-07-10 2024-09-12 Sartorius Stedim Biotech Gmbh Vorrichtung, Verwendung dieser Vorrichtung und Verfahren für die Stofftrennung mit verbesserter Ausnutzung der Kapazität chromatographischer Medien
US20170298091A1 (en) 2014-12-08 2017-10-19 Emd Millipore Corporation Mixed Bed Ion Exchange Adsorber
CN107921407B (zh) 2015-06-05 2022-07-05 格雷斯公司 生物处理吸附澄清剂及其制备和使用方法
WO2017176735A1 (fr) * 2016-04-05 2017-10-12 Haemonetics Corporation Procédés et dispositifs pour l'enrichissement d'immunoglobuline à partir du sang
CN107964044B (zh) * 2016-10-19 2021-11-19 无锡科捷诺生物科技有限责任公司 从乳样中纯化抗cd20单克隆抗体的方法
US11155575B2 (en) 2018-03-21 2021-10-26 Waters Technologies Corporation Non-antibody high-affinity-based sample preparation, sorbent, devices and methods
EP3546475A1 (fr) 2018-03-27 2019-10-02 Sanofi Processus d'écoulement intégral pour purifier des protéines recombinées
US20210380638A1 (en) * 2018-12-21 2021-12-09 WuXi Biologics Ireland Limited A method for improving aggregate removal by Protein A chromatography
FR3099066B1 (fr) 2019-07-26 2021-08-13 Novasep Process Procédé de purification d’une substance cible avec inactivation virale
TW202128264A (zh) 2019-09-25 2021-08-01 瑞士商赫孚孟拉羅股份公司 使用經預測之溶離緩衝鹽濃度的陽離子層析法
WO2021064079A1 (fr) * 2019-10-04 2021-04-08 Merck Patent Gmbh Purification de protéines et inactivation virale
CN110724204B (zh) * 2019-11-18 2021-10-22 广东菲鹏制药股份有限公司 Fc融合蛋白的纯化方法
CN113845562A (zh) * 2020-06-28 2021-12-28 佛山汉腾生物科技有限公司 目的蛋白纯化方法

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Also Published As

Publication number Publication date
EP2462157A4 (fr) 2012-12-26
US20110065901A1 (en) 2011-03-17
KR101415660B1 (ko) 2014-07-16
EP2462157A1 (fr) 2012-06-13
EP2462157B1 (fr) 2020-06-17
WO2011017514A1 (fr) 2011-02-10
JP5791602B2 (ja) 2015-10-07
ES2817802T3 (es) 2021-04-08
CN102574911A (zh) 2012-07-11
US8536316B2 (en) 2013-09-17
JP2013501721A (ja) 2013-01-17
SG177577A1 (en) 2012-03-29
KR20120089432A (ko) 2012-08-10
JP6335838B2 (ja) 2018-05-30
CN107188960A (zh) 2017-09-22
JP2015157846A (ja) 2015-09-03
CN102574911B (zh) 2017-06-06

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