IS2974B - Asaspíróalkanafleiður sem tálmar málmpróteinkljúfa - Google Patents

Asaspíróalkanafleiður sem tálmar málmpróteinkljúfa

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Publication number
IS2974B
IS2974B IS8140A IS8140A IS2974B IS 2974 B IS2974 B IS 2974B IS 8140 A IS8140 A IS 8140A IS 8140 A IS8140 A IS 8140A IS 2974 B IS2974 B IS 2974B
Authority
IS
Iceland
Prior art keywords
azaspiroalkane
derivatives
protein cleavage
inhibit metal
metal protein
Prior art date
Application number
IS8140A
Other languages
English (en)
Other versions
IS8140A (is
Inventor
Yao Wenqing
Zhou Jincong
Xu Meizhong
Zhang Fenglei
Metcalf Brian
Original Assignee
Incyte Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Corporation filed Critical Incyte Corporation
Publication of IS8140A publication Critical patent/IS8140A/is
Publication of IS2974B publication Critical patent/IS2974B/is

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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