IS4588A - Bensimídazól efnasambönd, lyfjablöndur sem innihalda efnasamböndin og notkun þeirra - Google Patents

Bensimídazól efnasambönd, lyfjablöndur sem innihalda efnasamböndin og notkun þeirra

Info

Publication number: IS4588A
Authority: IS; Iceland
Prior art keywords: compounds; phenyl; disorders; pharmaceutical compositions; compositions containing
Prior art date: 1995-04-21

Application number

IS4588A

Other languages

English (en)

Other versions

IS1959B (is

Inventor

Teuber Lene

Vätjen Frank

Fukuda Yoshimasa

Ushiroda Osamu

Sasaki Toshiro

Original Assignee

Neurosearch A/S

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-04-21

Filing date

1997-10-13

Publication date

1997-10-13

1997-10-13 Application filed by Neurosearch A/S filed Critical Neurosearch A/S

1997-10-13 Publication of IS4588A publication Critical patent/IS4588A/is

2004-11-15 Publication of IS1959B publication Critical patent/IS1959B/is

Links

150000001875 compounds Chemical class 0.000 title abstract 3
125000003785 benzimidazolyl group Chemical class N1=C(NC2=C1C=CC=C2)* 0.000 title abstract 2
239000008194 pharmaceutical composition Substances 0.000 title 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 4
125000003545 alkoxy group Chemical group 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 2
229910052736 halogen Inorganic materials 0.000 abstract 2
150000002367 halogens Chemical class 0.000 abstract 2
125000001424 substituent group Chemical group 0.000 abstract 2
208000019901 Anxiety disease Diseases 0.000 abstract 1
206010010904 Convulsion Diseases 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
208000026139 Memory disease Diseases 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
125000004442 acylamino group Chemical group 0.000 abstract 1
230000036506 anxiety Effects 0.000 abstract 1
208000015114 central nervous system disease Diseases 0.000 abstract 1
125000004093 cyano group Chemical group *C#N 0.000 abstract 1
206010015037 epilepsy Diseases 0.000 abstract 1
125000002541 furyl group Chemical group 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000000842 isoxazolyl group Chemical group 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
208000019116 sleep disease Diseases 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A61P25/12—Antiepileptics; Anticonvulsants for grand-mal
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D521/00—Heterocyclic compounds containing unspecified hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Neurosurgery (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Anesthesiology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

IS4588A 1995-04-21 1997-10-13 Bensimídazól efnasambönd, lyfjablöndur sem innihalda efnasamböndin og notkun þeirra IS1959B (is)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DK46095		1995-04-21
PCT/EP1996/001606 WO1996033194A1 (en)	1995-04-21	1996-04-17	Benzimidazole compounds and their use as modulators of the gaba a receptor complex

Publications (2)

Publication Number	Publication Date
IS4588A true IS4588A (is)	1997-10-13
IS1959B IS1959B (is)	2004-11-15

Family

ID=8093808

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IS4588A IS1959B (is)	1995-04-21	1997-10-13	Bensimídazól efnasambönd, lyfjablöndur sem innihalda efnasamböndin og notkun þeirra

Country Status (22)

Country	Link
US (2)	US5922724A (is)
EP (3)	EP0821684B1 (is)
JP (2)	JP3342874B2 (is)
KR (2)	KR100297445B1 (is)
CN (2)	CN1072669C (is)
AT (2)	ATE210132T1 (is)
AU (2)	AU695957B2 (is)
BR (1)	BR9608048A (is)
CA (2)	CA2218493C (is)
CZ (1)	CZ287545B6 (is)
DE (2)	DE69617665T2 (is)
EE (1)	EE04310B1 (is)
HU (1)	HUP9801692A3 (is)
IS (1)	IS1959B (is)
NO (1)	NO314504B1 (is)
NZ (1)	NZ307521A (is)
PL (1)	PL183853B1 (is)
RU (1)	RU2135493C1 (is)
SK (1)	SK282425B6 (is)
TR (1)	TR199701218T2 (is)
UA (1)	UA54393C2 (is)
WO (2)	WO1996033194A1 (is)

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US6380210B1 (en)	1999-04-02	2002-04-30	Neurogen Corporation	Heteroaryl fused aminoalkyl-imidazole derivatives: selective modulators of GABAa receptors
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GB0208394D0 (en) *	2002-04-11	2002-05-22	Merck Sharp & Dohme	Therapeutic agents
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ATE386519T1 (de)	2003-04-03	2008-03-15	Neurosearch As	Benzimidazole derivate und ihre anwendung als gaba a rezeptor komplex modulatoren
AU2004226179A1 (en)	2003-04-03	2004-10-14	Neurosearch A/S	Benzimidazole derivatives and their use for modulating the GABA-a receptor complex
US7700638B2 (en) *	2003-10-23	2010-04-20	N. V. Organon	1,5,7-trisubstituted benzimidazole derivatives and their use for modulating the GABAA receptor complex
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DE2853765A1 (de) *	1978-12-13	1980-06-26	Bayer Ag	Verfahren zur herstellung von benzimidazolylbenzofuranen
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PH30434A (en) *	1989-04-07	1997-05-09	Janssen Pharmaceutica Nv	Hydroxyalkylfuranyl derivatives
AU675484B2 (en) *	1993-03-24	1997-02-06	Neurosearch A/S	Benzimidazole compounds, their use and preparation
US5554630A (en) *	1993-03-24	1996-09-10	Neurosearch A/S	Benzimidazole compounds

1996
- 1996-04-17 RU RU97119173A patent/RU2135493C1/ru not_active IP Right Cessation
- 1996-04-17 UA UA97115591A patent/UA54393C2/uk unknown
- 1996-04-17 AT AT96914932T patent/ATE210132T1/de not_active IP Right Cessation
- 1996-04-17 EP EP96914932A patent/EP0821684B1/en not_active Expired - Lifetime
- 1996-04-17 CZ CZ19973292A patent/CZ287545B6/cs not_active IP Right Cessation
- 1996-04-17 HU HU9801692A patent/HUP9801692A3/hu unknown
- 1996-04-17 PL PL96322892A patent/PL183853B1/pl not_active IP Right Cessation
- 1996-04-17 EP EP01112476A patent/EP1164134A1/en not_active Withdrawn
- 1996-04-17 JP JP53146496A patent/JP3342874B2/ja not_active Expired - Fee Related
- 1996-04-17 EE EE9700283A patent/EE04310B1/xx not_active IP Right Cessation
- 1996-04-17 CN CN96193419A patent/CN1072669C/zh not_active Expired - Fee Related
- 1996-04-17 BR BR9608048-5A patent/BR9608048A/pt not_active IP Right Cessation
- 1996-04-17 TR TR97/01218T patent/TR199701218T2/xx unknown
- 1996-04-17 US US08/945,023 patent/US5922724A/en not_active Expired - Lifetime
- 1996-04-17 NZ NZ307521A patent/NZ307521A/en unknown
- 1996-04-17 SK SK1399-97A patent/SK282425B6/sk unknown
- 1996-04-17 WO PCT/EP1996/001606 patent/WO1996033194A1/en not_active Ceased
- 1996-04-17 CA CA002218493A patent/CA2218493C/en not_active Expired - Fee Related
- 1996-04-17 DE DE69617665T patent/DE69617665T2/de not_active Expired - Lifetime
- 1996-04-17 AU AU56891/96A patent/AU695957B2/en not_active Ceased
- 1996-04-17 KR KR1019970707465A patent/KR100297445B1/ko not_active Expired - Fee Related
- 1996-04-19 DE DE69636670T patent/DE69636670T2/de not_active Expired - Lifetime
- 1996-04-19 WO PCT/EP1996/001654 patent/WO1996033192A1/en not_active Ceased
- 1996-04-19 US US08/930,216 patent/US5902813A/en not_active Expired - Lifetime
- 1996-04-19 CA CA002217601A patent/CA2217601C/en not_active Expired - Fee Related
- 1996-04-19 EP EP96912025A patent/EP0821683B1/en not_active Expired - Lifetime
- 1996-04-19 JP JP8531487A patent/JP3040485B2/ja not_active Expired - Fee Related
- 1996-04-19 CN CN96193420A patent/CN1182426A/zh active Pending
- 1996-04-19 KR KR1019970707464A patent/KR19990007941A/ko not_active Abandoned
- 1996-04-19 AU AU55014/96A patent/AU5501496A/en not_active Abandoned
- 1996-04-19 AT AT96912025T patent/ATE344257T1/de not_active IP Right Cessation
1997
- 1997-10-13 IS IS4588A patent/IS1959B/is unknown
- 1997-10-20 NO NO19974844A patent/NO314504B1/no unknown

Also Published As

Publication number	Publication date
HUP9801692A2 (hu)	1999-03-29
WO1996033192A1 (en)	1996-10-24
AU695957B2 (en)	1998-08-27
KR19990007942A (ko)	1999-01-25
CA2218493A1 (en)	1996-10-24
EP0821684A1 (en)	1998-02-04
CA2217601C (en)	2002-04-16
DE69617665D1 (de)	2002-01-17
PL183853B1 (pl)	2002-07-31
ATE344257T1 (de)	2006-11-15
DE69617665T2 (de)	2002-05-08
EE9700283A (et)	1998-06-15
TR199701218T2 (xx)	1998-08-21
WO1996033194A1 (en)	1996-10-24
RU2135493C1 (ru)	1999-08-27
NO314504B1 (no)	2003-03-31
CN1182426A (zh)	1998-05-20
NZ307521A (en)	1999-04-29
BR9608048A (pt)	1999-11-30
SK139997A3 (en)	1998-05-06
SK282425B6 (sk)	2002-01-07
IS1959B (is)	2004-11-15
CN1182427A (zh)	1998-05-20
HUP9801692A3 (en)	2001-11-28
CN1072669C (zh)	2001-10-10
AU5501496A (en)	1996-11-07
JPH11501320A (ja)	1999-02-02
CA2217601A1 (en)	1996-10-24
CA2218493C (en)	2005-02-22
EP0821683B1 (en)	2006-11-02
EP0821684B1 (en)	2001-12-05
AU5689196A (en)	1996-11-07
EP0821683A1 (en)	1998-02-04
KR100297445B1 (ko)	2001-10-25
NO974844D0 (no)	1997-10-20
ATE210132T1 (de)	2001-12-15
DE69636670T2 (de)	2007-02-08
CZ287545B6 (en)	2000-12-13
UA54393C2 (uk)	2003-03-17
CZ329297A3 (cs)	1998-03-18
JPH11501321A (ja)	1999-02-02
JP3342874B2 (ja)	2002-11-11
KR19990007941A (ko)	1999-01-25
US5922724A (en)	1999-07-13
DE69636670D1 (de)	2006-12-14
US5902813A (en)	1999-05-11
JP3040485B2 (ja)	2000-05-15
EE04310B1 (et)	2004-06-15
EP1164134A1 (en)	2001-12-19
NO974844L (no)	1997-12-16
PL322892A1 (en)	1998-03-02
HK1015674A1 (en)	1999-10-22

Publication	Publication Date	Title
IS1959B (is)	2004-11-15	Bensimídazól efnasambönd, lyfjablöndur sem innihalda efnasamböndin og notkun þeirra
IS4593A (is)	1997-10-17	Bensimídazól efnasambönd, lyfjablöndur sem innihalda efnasamböndin og notkun þeirra
NO941052L (no)	1994-09-26	Benzimidazolforbindelser, deres anvendelse og fremstilling
ATE163012T1 (de)	1998-02-15	N-substituierte 4-pyrimidinamine und - pyrimidindiamine, verfahren zu ihrer herstellung und ihre anwendung als arzneimittel
ES2117795T3 (es)	1998-08-16	Derivados de acetamida y su uso como modificadores del comportamiento de toma alimentaria.
WO2002094794A8 (en)	2004-04-22	4 (phenyl-piperazinyl-methyl) benzamide derivatives and their use for the treatment of pain anxiety or gastrointestinal disorders
DE69418789D1 (de)	1999-07-08	2-(Piperidin-4-yl, Pyridin-4-yl und Tetrahydropyridin-4-yl)-benzofuran-7-carbamat Derivate, ihre Herstellung und Verwendung als Acetylcholinesterase Inhibitoren
ATE412628T1 (de)	2008-11-15	N- (1-dimethylaminocycloalkyl)methyl benzamid- derivate
DK1242406T3 (da)	2004-06-28	Hidtil ukendte forbindelser
DE69402935D1 (de)	1997-06-05	Substituierte arylalkylaminobenzyl-aminopropanamide, ihre herstellung und verwendung als antiepileptische, neuroprotektive und antidepressive mittel
ATE171939T1 (de)	1998-10-15	Phenoxyphenylcyclopentenyl-hydroxyharnstoffe
ATE266026T1 (de)	2004-05-15	Benzofurancarboxamide und deren therapeutische verwendung
WO2000008020A3 (en)	2000-07-13	Tricyclic carboxamides
ATE162191T1 (de)	1998-01-15	Azanoradamantane
MX9708096A (es)	1998-01-31	Compuestos de bencimidazol y su uso para preparar composiciones utiles como moduladores del complejo receptor de gabaa.
TW429147B (en)	2001-04-11	Pharmaceutical composition for the treatment of CNS disorders
KR910000143A (ko)	1991-01-29	간질치료제로서의 5-페닐-2- 푸란 에스테르 및 아미드의 용도
DK1049670T3 (da)	2002-11-11	Azetidincarboxamidderivater til behandling af CNS-lidelser