IS5447A - Ferli til að smíða 1,3-díól - Google Patents

Ferli til að smíða 1,3-díól

Info

Publication number
IS5447A
IS5447A IS5447A IS5447A IS5447A IS 5447 A IS5447 A IS 5447A IS 5447 A IS5447 A IS 5447A IS 5447 A IS5447 A IS 5447A IS 5447 A IS5447 A IS 5447A
Authority
IS
Iceland
Prior art keywords
diol
making
Prior art date
Application number
IS5447A
Other languages
English (en)
Inventor
Lee Bosch Robert
Joseph Mccabe Richard
Norman Nanninga Thomas
Joseph Stahl Robert
Original Assignee
Warner-Lambert Export Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner-Lambert Export Limited filed Critical Warner-Lambert Export Limited
Publication of IS5447A publication Critical patent/IS5447A/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C07D207/40—2,5-Pyrrolidine-diones
    • C07D207/416—2,5-Pyrrolidine-diones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B41/00—Formation or introduction of functional groups containing oxygen
    • C07B41/02—Formation or introduction of functional groups containing oxygen of hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/19—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and carboxyl groups, other than cyano groups, bound to the same saturated acyclic carbon skeleton
    • C07C255/20—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and carboxyl groups, other than cyano groups, bound to the same saturated acyclic carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/19—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and carboxyl groups, other than cyano groups, bound to the same saturated acyclic carbon skeleton
    • C07C255/21—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and carboxyl groups, other than cyano groups, bound to the same saturated acyclic carbon skeleton the carbon skeleton being further substituted by doubly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Pyrrole Compounds (AREA)
IS5447A 1997-12-19 2000-04-14 Ferli til að smíða 1,3-díól IS5447A (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6819397P 1997-12-19 1997-12-19
PCT/US1998/025493 WO1999032434A1 (en) 1997-12-19 1998-12-02 Process for the synthesis of 1,3-diols

Publications (1)

Publication Number Publication Date
IS5447A true IS5447A (is) 2000-04-14

Family

ID=22081016

Family Applications (1)

Application Number Title Priority Date Filing Date
IS5447A IS5447A (is) 1997-12-19 2000-04-14 Ferli til að smíða 1,3-díól

Country Status (31)

Country Link
US (4) US6433213B1 (is)
EP (1) EP1054860B1 (is)
JP (1) JP2001526256A (is)
KR (2) KR100681366B1 (is)
AR (1) AR014943A1 (is)
AT (1) ATE360608T1 (is)
AU (1) AU755543B2 (is)
BR (1) BR9813760A (is)
CA (1) CA2305618C (is)
CO (1) CO4990941A1 (is)
CU (1) CU22939A3 (is)
CY (1) CY1106612T1 (is)
DE (1) DE69837681T2 (is)
DK (1) DK1054860T3 (is)
ES (1) ES2284219T3 (is)
GT (2) GT199800197AA (is)
HN (1) HN1998000187A (is)
HU (1) HUP0100252A3 (is)
IL (1) IL135562A (is)
IS (1) IS5447A (is)
MY (1) MY118726A (is)
NO (1) NO20003139D0 (is)
NZ (1) NZ504346A (is)
PA (1) PA8464901A1 (is)
PE (1) PE20000136A1 (is)
PL (1) PL193678B1 (is)
PT (1) PT1054860E (is)
SV (1) SV1998000153A (is)
TW (1) TW444000B (is)
WO (1) WO1999032434A1 (is)
ZA (1) ZA9811586B (is)

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US7300775B2 (en) 1999-12-29 2007-11-27 Verenium Corporation Methods for producing α-substituted carboxylic acids using nitrilases and strecker reagents
US7521216B2 (en) * 1999-12-29 2009-04-21 Verenium Corporation Nitrilases and methods for making and using them
US20040014195A1 (en) * 1999-12-29 2004-01-22 Diversa Corporation Nitrilases, nucleic acids encoding them and methods for making and using them
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US7317123B2 (en) 2001-07-06 2008-01-08 Teva Pharmaceutical Industries, Ltd Process for preparation of 7-amino syn 3,5-dihydroxy heptanoic acid derivatives, intermediates thereof and methods for their preparation
GB0211715D0 (en) * 2002-05-22 2002-07-03 Phoenix Chemicals Ltd Process
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US7790197B2 (en) * 2003-06-09 2010-09-07 Warner-Lambert Company Llc Pharmaceutical compositions of atorvastatin
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US7655692B2 (en) * 2003-06-12 2010-02-02 Pfizer Inc. Process for forming amorphous atorvastatin
US20050271717A1 (en) * 2003-06-12 2005-12-08 Alfred Berchielli Pharmaceutical compositions of atorvastatin
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CA2535147A1 (en) * 2003-08-11 2005-05-19 Codexis, Inc. Improved glucose dehydrogenase polypeptides and related polynucleotides
US7588928B2 (en) * 2003-08-11 2009-09-15 Codexis, Inc. Halohydrin dehalogenases and related polynucleotides
CA2533838A1 (en) * 2003-08-11 2005-02-24 Codexis, Inc. Improved ketoreductase polypeptides and related polynucleotides
WO2005017141A1 (en) * 2003-08-11 2005-02-24 Codexis, Inc. Improved halohydrin dehalogenases and related polynucleotides
KR20060071397A (ko) * 2003-08-11 2006-06-26 코덱시스, 인코포레이티드 4-치환된 3-히드록시부티르산 유도체 및 이웃자리 시아노,히드록시 치환된 카르복실산 에스테르의 효소적 제조 방법
US20070276027A1 (en) * 2003-09-17 2007-11-29 Warner-Lambert Company Llc Crystalline Forms of [R-(R* ,R*)]-2-(4-Fluorophenyl)-Beta, -Dihydroxy-5-(1-Methylethyl)-3-Phenyl-4-[(Phenylamino)Carbonyl]-1H-Pyrrole-1-Heptanoic Acid
AU2003272080A1 (en) * 2003-09-18 2005-04-06 Biocon Limited Novel process for the preparation of tert-butyl 6-cyano-5-hydroxy-3-oxohexanoate
CA2645396A1 (en) * 2003-12-24 2005-07-14 Teva Pharmaceutical Industries, Ltd Process for preparation of statins with high syn to anti ratio
US7851624B2 (en) * 2003-12-24 2010-12-14 Teva Pharamaceutical Industries Ltd. Triol form of rosuvastatin and synthesis of rosuvastatin
AU2005232959A1 (en) * 2004-04-16 2005-10-27 Pfizer Products Inc. Process for forming amorphous atorvastatin calcium
US7875731B2 (en) 2004-05-05 2011-01-25 Pfizer Inc. Salt forms of [R-(R*,R*)]-2-(4-fluorophenyl)-β, δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)Carbonyl]-1H-pyrrole-1-heptanoic acid
AU2005263550C1 (en) * 2004-07-16 2013-01-17 Lek Pharmaceuticals D.D. Oxidative degradation products of atorvastatin calcium
CA2672554C (en) 2004-07-20 2012-01-03 Warner-Lambert Company Llc Novel forms of [r-(r*,r*)]-2-(4-fluorophenyl).beta.,.delta.-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrole-1-heptanoic acid calcium salt (2:1)
EP1807055A1 (en) * 2004-10-28 2007-07-18 Warner-Lambert Company LLC Process for forming amorphous atorvastatin
MX2007005137A (es) 2004-11-23 2007-06-22 Warner Lambert Co Derivados del acido 7-(2h-pyrazol-3-il)-3, 5-dihidroxi-heptanoico como inhibidores de hmg co-a reductasa para el tratamiento de lipidemia.
JP2008521878A (ja) * 2004-12-02 2008-06-26 ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー 非晶質アトルバスタチンの医薬組成物及びその製造のための方法
WO2007029217A1 (en) * 2005-09-09 2007-03-15 Pfizer Science And Technology Ireland Limited Preparation of an atorvastatin intermediate
EP1922315B1 (en) * 2005-09-09 2009-05-27 Pfizer Science and Technology Ireland Limited Preparation of an atorvastatin intermediate
CA2547216A1 (en) 2005-09-21 2007-03-21 Renuka D. Reddy Process for annealing amorphous atorvastatin
DK1957452T3 (da) 2005-11-21 2010-07-26 Warner Lambert Co Nye former af [R-(R*,R*)]-2-(4-fluorphenyl)-B,B-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-heptansyre- magnesium
US7879585B2 (en) 2006-10-02 2011-02-01 Codexis, Inc. Ketoreductase enzymes and uses thereof
US9217164B2 (en) 2007-03-01 2015-12-22 Basf Enzymes Llc Nitrilases, nucleic acids encoding them and methods for making and using them
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Also Published As

Publication number Publication date
CU22939A3 (es) 2004-04-13
CY1106612T1 (el) 2012-01-25
PE20000136A1 (es) 2000-03-11
HUP0100252A1 (hu) 2001-07-30
CO4990941A1 (es) 2000-12-26
US6433213B1 (en) 2002-08-13
CA2305618C (en) 2004-08-17
US20050197500A1 (en) 2005-09-08
NZ504346A (en) 2001-11-30
SV1998000153A (es) 1999-09-30
PL193678B1 (pl) 2007-03-30
PA8464901A1 (es) 2000-05-24
MY118726A (en) 2005-01-31
KR20060080941A (ko) 2006-07-11
US20020161021A1 (en) 2002-10-31
US7232915B2 (en) 2007-06-19
WO1999032434A1 (en) 1999-07-01
DE69837681D1 (de) 2007-06-06
IL135562A (en) 2005-08-31
AU1707499A (en) 1999-07-12
US6596879B2 (en) 2003-07-22
BR9813760A (pt) 2000-10-03
AU755543B2 (en) 2002-12-12
KR100668575B1 (ko) 2007-01-17
KR100681366B1 (ko) 2007-02-12
NO20003139L (no) 2000-06-16
ES2284219T3 (es) 2007-11-01
GT199800197AA (es) 2000-06-06
HUP0100252A3 (en) 2002-12-28
GT199800197A (es) 2000-06-06
US20040006231A1 (en) 2004-01-08
ATE360608T1 (de) 2007-05-15
KR20010033315A (ko) 2001-04-25
PL341294A1 (en) 2001-04-09
NO20003139D0 (no) 2000-06-16
US6962994B2 (en) 2005-11-08
ZA9811586B (en) 1999-06-17
AR014943A1 (es) 2001-04-11
TW444000B (en) 2001-07-01
HN1998000187A (es) 1999-10-22
PT1054860E (pt) 2007-06-22
IL135562A0 (en) 2001-05-20
EP1054860B1 (en) 2007-04-25
DE69837681T2 (de) 2008-01-10
CA2305618A1 (en) 1999-07-01
DK1054860T3 (da) 2007-07-02
JP2001526256A (ja) 2001-12-18
EP1054860A1 (en) 2000-11-29

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