IS8178A - Oxazólidinon fúkalyf setin með sýklóprópýlhóp og afleiður þeirra - Google Patents

Oxazólidinon fúkalyf setin með sýklóprópýlhóp og afleiður þeirra

Info

Publication number: IS8178A
Authority: IS; Iceland
Prior art keywords: fukuyl; oxazolidinone; derivatives; substituted; cyclopropyl group
Prior art date: 2003-07-02

Application number

IS8178A

Other languages

English (en)

Inventor

Fukuda Yasumichi

Original Assignee

Merck & Co., Inc.

Kyorin Pharmaceutical Co., Ltd.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-07-02

Filing date

2005-12-13

Publication date

2005-12-13

2005-12-13 Application filed by Merck & Co., Inc., Kyorin Pharmaceutical Co., Ltd. filed Critical Merck & Co., Inc.

2005-12-13 Publication of IS8178A publication Critical patent/IS8178A/is

Links

IZXIZTKNFFYFOF-UHFFFAOYSA-N 2-Oxazolidone Chemical compound O=C1NCCO1 IZXIZTKNFFYFOF-UHFFFAOYSA-N 0.000 title 1
125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Diabetes (AREA)
Hematology (AREA)
Neurology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Nutrition Science (AREA)
Pain & Pain Management (AREA)
Dermatology (AREA)
Obesity (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

IS8178A 2003-07-02 2005-12-13 Oxazólidinon fúkalyf setin með sýklóprópýlhóp og afleiður þeirra IS8178A (is)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US48390403P	2003-07-02	2003-07-02
US54698404P	2004-02-24	2004-02-24
PCT/US2004/020734 WO2005005398A2 (en)	2003-07-02	2004-06-29	Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereof

Publications (1)

Publication Number	Publication Date
IS8178A true IS8178A (is)	2005-12-13

Family

ID=34068173

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IS8178A IS8178A (is)	2003-07-02	2005-12-13	Oxazólidinon fúkalyf setin með sýklóprópýlhóp og afleiður þeirra

Country Status (23)

Country	Link
US (2)	US7462633B2 (is)
EP (1)	EP1646629B1 (is)
JP (1)	JP4607107B2 (is)
KR (1)	KR20060113625A (is)
AR (1)	AR044990A1 (is)
AT (1)	ATE471937T1 (is)
AU (1)	AU2004256083B2 (is)
BR (1)	BRPI0411688A (is)
CA (1)	CA2530140C (is)
CL (1)	CL2004001678A1 (is)
DE (1)	DE602004027811D1 (is)
EC (1)	ECSP056257A (is)
IL (1)	IL172785A0 (is)
IS (1)	IS8178A (is)
MA (1)	MA27938A1 (is)
MX (1)	MXPA06000228A (is)
MY (1)	MY140137A (is)
NO (1)	NO20060558L (is)
NZ (1)	NZ544237A (is)
PE (1)	PE20050732A1 (is)
RU (1)	RU2348628C2 (is)
TW (1)	TW200510421A (is)
WO (1)	WO2005005398A2 (is)

Families Citing this family (22)

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US6897230B2 (en) *	2001-04-17	2005-05-24	Kyorin Pharmaceutical Co., Ltd.	Bicyclo[3/1/0] hexane containing oxazolidinone antibiotics and derivatives thereof
US8324398B2 (en)	2003-06-03	2012-12-04	Rib-X Pharmaceuticals, Inc.	Process for the synthesis of biaryl oxazolidinones
PT1656370E (pt)	2003-06-03	2012-11-29	Rib X Pharmaceuticals Inc	Compostos biaril-heterocíclicos e métodos de os produzir e de os utilizar
CA2529294A1 (en) *	2003-07-02	2005-01-20	Merck & Co., Inc.	Oxazolidinone antibiotics and derivatives thereof
ATE471937T1 (de)	2003-07-02	2010-07-15	Merck Sharp & Dohme	Cyclopropylgruppensubstituierte oxazolidinonantibiotika und derivate davon
TW200526649A (en) *	2003-12-17	2005-08-16	Rib X Pharmaceuticals Inc	Halogenated biaryl heterocyclic compounds and methods of making and using the same
KR100854211B1 (ko)	2003-12-18	2008-08-26	동아제약주식회사	신규한 옥사졸리디논 유도체, 그의 제조방법 및 이를유효성분으로 하는 항생제용 약학 조성물
EP1799677A1 (en) *	2004-10-08	2007-06-27	Ranbaxy Laboratories Limited	Oxazolidinone derivatives as antimicrobials
DE602006019870D1 (de)	2005-06-08	2011-03-10	Rib X Pharmaceuticals Inc	Verfahren zur synthese von triazolen
WO2007023507A2 (en) *	2005-06-20	2007-03-01	Wockhardt Limited	Oxazolidinones bearing antimicrobial activity composition and methods of preparation
US7838526B2 (en) *	2005-08-05	2010-11-23	Esther Baldinger	Method of treating neurological disorders
AR054608A1 (es) *	2005-08-08	2007-06-27	Actelion Pharmaceuticals Ltd	Derivados de oxazolidinona enlazados a quinolonas como antibacterianos
JP2010528007A (ja) *	2007-05-23	2010-08-19	メルク・シャープ・エンド・ドーム・コーポレイション	シクロプロピルピロリジンオレキシン受容体アンタゴニスト
MX2011003820A (es)	2008-10-10	2011-06-16	Trius Therapeutics	Metodos para preparar oxazolidinonas y composiciones que las contienen.
SG173497A1 (en)	2009-02-03	2011-09-29	Trius Therapeutics	Crystalline form of r)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyl oxazolidin-2-one dihydrogen phosphate
US8580767B2 (en) *	2009-05-28	2013-11-12	Trius Therapeutics, Inc.	Oxazolidinone containing dimer compounds, compositions and methods to make and use
CA2765692A1 (en)	2009-06-26	2010-12-29	Panacea Biotec Ltd.	Novel azabicyclohexanes
EP2621902B1 (en)	2010-09-28	2017-04-12	Panacea Biotec Ltd	3-azabicyclo[3.1.0]hexane compounds useful for the treatment of cns disorders
WO2017066964A1 (en)	2015-10-22	2017-04-27	Merck Sharp & Dohme Corp.	Oxazolidinone compounds and methods of use thereof as antibacterial agents
KR102777328B1 (ko)	2018-07-25	2025-03-10	자이두스 라이프사이언시즈 리미티드	포유류 감염 치료를 위한 신규 화합물
US20220289751A1 (en) *	2019-07-17	2022-09-15	Ono Pharmaceutical Co., Ltd.	Compound having kdm5 inhibitory activity and pharmaceutical use thereof
WO2021184339A1 (en)	2020-03-20	2021-09-23	Merck Sharp & Dohme Corp.	Oxazolidinone compound and methods of use thereof as an antibacterial agent

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CN1155585C (zh)	2001-12-19	2004-06-30	中国医学科学院医药生物技术研究所	3,5－取代噁唑烷酮衍生物及其制备方法和应用
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AR038536A1 (es)	2002-02-25	2005-01-19	Upjohn Co	N-aril-2-oxazolidinona-5- carboxamidas y sus derivados
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JP2005529924A (ja)	2002-05-15	2005-10-06	ランバクシーラボラトリーズリミテッド	フェニルオキサゾリジノン誘導体
US6875784B2 (en)	2002-10-09	2005-04-05	Pharmacia & Upjohn Company	Antimibicrobial [3.1.0.] bicyclic oxazolidinone derivatives
EP1581524A2 (en) *	2002-11-28	2005-10-05	AstraZeneca AB	Oxazolidinones as antibacterial agents
TW200500360A (en)	2003-03-01	2005-01-01	Astrazeneca Ab	Hydroxymethyl compounds
JP2006522791A (ja) *	2003-04-09	2006-10-05	ファルマシア・アンド・アップジョン・カンパニー・エルエルシー	抗微生物性［３．１．０］ビシクロヘキシルフェニルオキサゾリジノン誘導体および類似体
WO2004099199A1 (en)	2003-05-06	2004-11-18	Ranbaxy Laboratories Limited	Oxazolidinone derivatives as antimicrobials
CA2529294A1 (en)	2003-07-02	2005-01-20	Merck & Co., Inc.	Oxazolidinone antibiotics and derivatives thereof
ATE471937T1 (de)	2003-07-02	2010-07-15	Merck Sharp & Dohme	Cyclopropylgruppensubstituierte oxazolidinonantibiotika und derivate davon
US20060247286A1 (en) *	2003-07-02	2006-11-02	Milton Hammond	Oxazolidinone antibiotics and derivatives thereof
AU2004256085B2 (en)	2003-07-02	2007-12-06	Kyorin, Pharmaceutical Co., Ltd.	Cyclopropyl Group Substituted Oxazolydinone Antibiotics and Derivatives Thereof

2004
- 2004-06-29 AT AT04777196T patent/ATE471937T1/de not_active IP Right Cessation
- 2004-06-29 KR KR1020067000071A patent/KR20060113625A/ko not_active Ceased
- 2004-06-29 AU AU2004256083A patent/AU2004256083B2/en not_active Ceased
- 2004-06-29 DE DE602004027811T patent/DE602004027811D1/de not_active Expired - Lifetime
- 2004-06-29 CA CA2530140A patent/CA2530140C/en not_active Expired - Fee Related
- 2004-06-29 BR BRPI0411688-7A patent/BRPI0411688A/pt not_active IP Right Cessation
- 2004-06-29 US US10/878,637 patent/US7462633B2/en not_active Expired - Fee Related
- 2004-06-29 MX MXPA06000228A patent/MXPA06000228A/es active IP Right Grant
- 2004-06-29 NZ NZ544237A patent/NZ544237A/en unknown
- 2004-06-29 WO PCT/US2004/020734 patent/WO2005005398A2/en not_active Ceased
- 2004-06-29 EP EP04777196A patent/EP1646629B1/en not_active Expired - Lifetime
- 2004-06-29 JP JP2006517736A patent/JP4607107B2/ja not_active Expired - Fee Related
- 2004-06-29 RU RU2005140379/04A patent/RU2348628C2/ru not_active IP Right Cessation
- 2004-07-01 AR ARP040102330A patent/AR044990A1/es unknown
- 2004-07-01 MY MYPI20042639A patent/MY140137A/en unknown
- 2004-07-01 CL CL200401678A patent/CL2004001678A1/es unknown
- 2004-07-01 PE PE2004000629A patent/PE20050732A1/es not_active Application Discontinuation
- 2004-07-02 TW TW093120081A patent/TW200510421A/zh unknown
2005
- 2005-12-13 IS IS8178A patent/IS8178A/is unknown
- 2005-12-22 IL IL172785A patent/IL172785A0/en unknown
- 2005-12-28 EC EC2005006257A patent/ECSP056257A/es unknown
2006
- 2006-01-30 MA MA28763A patent/MA27938A1/fr unknown
- 2006-02-02 NO NO20060558A patent/NO20060558L/no not_active Application Discontinuation
2007
- 2007-01-22 US US11/655,840 patent/US7582659B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
AR044990A1 (es)	2005-10-12
US20050038092A1 (en)	2005-02-17
US7462633B2 (en)	2008-12-09
MA27938A1 (fr)	2006-06-01
RU2348628C2 (ru)	2009-03-10
AU2004256083A1 (en)	2005-01-20
CA2530140C (en)	2010-11-09
WO2005005398A2 (en)	2005-01-20
RU2005140379A (ru)	2007-08-10
TW200510421A (en)	2005-03-16
IL172785A0 (en)	2006-06-11
JP2007521281A (ja)	2007-08-02
MY140137A (en)	2009-11-30
NZ544237A (en)	2008-09-26
EP1646629B1 (en)	2010-06-23
ATE471937T1 (de)	2010-07-15
CA2530140A1 (en)	2005-01-20
MXPA06000228A (es)	2006-06-27
PE20050732A1 (es)	2005-11-02
NO20060558L (no)	2006-02-02
EP1646629A2 (en)	2006-04-19
ECSP056257A (es)	2006-04-19
AU2004256083B2 (en)	2007-10-11
BRPI0411688A (pt)	2006-12-26
KR20060113625A (ko)	2006-11-02
US7582659B2 (en)	2009-09-01
US20070203187A1 (en)	2007-08-30
DE602004027811D1 (de)	2010-08-05
CL2004001678A1 (es)	2005-05-20
JP4607107B2 (ja)	2011-01-05
WO2005005398A3 (en)	2005-04-28

Publication	Publication Date	Title
IS8178A (is)	2005-12-13	Oxazólidinon fúkalyf setin með sýklóprópýlhóp og afleiður þeirra
IS8074A (is)	2005-10-14	Setin 1,4- Díazepín og notkun theirra
MA29039B1 (fr)	2007-11-01	Dibenzylamines et derives
ATE422495T1 (de)	2009-02-15	Antibakterielle naphthydrin- und quinolinderivate
NO20054224D0 (no)	2005-09-12	Nye 2-pyridinkarboksamidderivater
IS8146A (is)	2005-11-24	Setnar 3-alkýl og 3-alkenýl asetidín afleiður
DOP2004000933A (es)	2005-05-18	Adjustment mechanism with torque limiting and antiloosening features
EP1692287A4 (en)	2007-03-28	BACTERIAL VIRULENT FACTORS AND USES THEREOF
DK1613694T3 (da)	2010-10-11	Polyalkenaminer med forbedrede anvendelsesegenskaber
ATE423117T1 (de)	2009-03-15	Heterocyclische 7-aminoalkylidenylchinolone und - naphthyridone
FR2875872B1 (fr)	2009-04-17	Entrainement
NO20054135D0 (no)	2005-09-06	Kipolinon/benzoksazin derivater og anvendelser derav
DE502004002283D1 (de)	2007-01-25	Pasteurisierungsanlage
IS7980A (is)	2005-08-12	Díarýlmetýlídenpíperidínafleiður, framleiðsla þeirra og notkun
SE0301502L (sv)	2004-05-25	Träningsanordning
DE60311121D1 (de)	2007-02-22	Trainingsgerät
EP1687399A4 (en)	2007-09-05	MODIFIED LUCIFERASE
NO20043603L (no)	2004-08-24	Koterapi med en oksazolidinon og et vitamin B
IS8489A (is)	2006-05-26	Umritunarstillar og aðferðir þeirra
FI20031330L (fi)	2005-03-18	Lajittelulaite ja -menetelmä
DE502004000456D1 (de)	2006-06-01	Ventilsteuerung
IS7961A (is)	2005-07-27	Díarýlmetýlídenpíperidínafleiður, lyfjablöndur þeirra og notkun þeirra
NO20055668D0 (no)	2005-11-30	Beta-amyloidinhibitorer og anvendelse derav
ATA14112002A (de)	2004-01-15	Schwenkschiebetür
IS8182A (is)	2005-12-14	Díarýlmetýlídenpíperídínafleiður, blöndur og notkun þeirra