IT7947706A0 - Derivati originali di 4-ammino-5-alchilsolfonil orto-anisammidi procedimento per la loro produzione e loro impiego come agenti psicotropici - Google Patents

Derivati originali di 4-ammino-5-alchilsolfonil orto-anisammidi procedimento per la loro produzione e loro impiego come agenti psicotropici

Info

Publication number
IT7947706A0
IT7947706A0 IT7947706A IT4770679A IT7947706A0 IT 7947706 A0 IT7947706 A0 IT 7947706A0 IT 7947706 A IT7947706 A IT 7947706A IT 4770679 A IT4770679 A IT 4770679A IT 7947706 A0 IT7947706 A0 IT 7947706A0
Authority
IT
Italy
Prior art keywords
anisamids
alkylsulfonyl
ortho
amino
procedure
Prior art date
Application number
IT7947706A
Other languages
English (en)
Other versions
IT1164655B (it
Original Assignee
Ile De France
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ile De France filed Critical Ile De France
Publication of IT7947706A0 publication Critical patent/IT7947706A0/it
Application granted granted Critical
Publication of IT1164655B publication Critical patent/IT1164655B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C07D207/09Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
IT47706/79A 1978-01-20 1979-01-18 Derivati originali di 4-ammino-5-alchilsolfonil orto-anisammidi procedimento per la loro produzione e loro impiego come agenti psicotropici IT1164655B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7801632A FR2415099A1 (fr) 1978-01-20 1978-01-20 Nouveaux derives de 4-amino-5-alkylsulfonyl ortho-anisamides, leurs procedes de preparation et leur application comme psychotropes

Publications (2)

Publication Number Publication Date
IT7947706A0 true IT7947706A0 (it) 1979-01-18
IT1164655B IT1164655B (it) 1987-04-15

Family

ID=9203689

Family Applications (1)

Application Number Title Priority Date Filing Date
IT47706/79A IT1164655B (it) 1978-01-20 1979-01-18 Derivati originali di 4-ammino-5-alchilsolfonil orto-anisammidi procedimento per la loro produzione e loro impiego come agenti psicotropici

Country Status (42)

Country Link
US (2) US4294828A (it)
JP (1) JPS6049192B2 (it)
AR (2) AR221354A1 (it)
AT (1) AT377977B (it)
AU (1) AU528561B2 (it)
BE (1) BE872585A (it)
BG (2) BG31496A3 (it)
CA (1) CA1101430A (it)
CH (1) CH637927A5 (it)
CS (1) CS226181B2 (it)
CY (1) CY1201A (it)
DD (1) DD141520A5 (it)
DE (1) DE2901181C2 (it)
DK (1) DK158346C (it)
EG (1) EG14045A (it)
ES (2) ES476755A1 (it)
FI (1) FI71126C (it)
FR (1) FR2415099A1 (it)
GB (2) GB2012765B (it)
GR (1) GR64431B (it)
HK (1) HK12184A (it)
HU (1) HU179793B (it)
IE (1) IE47798B1 (it)
IL (1) IL56411A (it)
IN (1) IN150226B (it)
IT (1) IT1164655B (it)
LU (1) LU80786A1 (it)
MC (1) MC1232A1 (it)
MX (2) MX5793E (it)
NL (1) NL191707C (it)
NO (1) NO151320C (it)
NZ (1) NZ189378A (it)
OA (1) OA06156A (it)
PH (2) PH15725A (it)
PL (2) PL116532B1 (it)
PT (1) PT69068A (it)
RO (2) RO76393A (it)
SE (2) SE448874B (it)
SU (1) SU820659A3 (it)
YU (2) YU42172B (it)
ZA (1) ZA79219B (it)
ZM (1) ZM579A1 (it)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2440946A2 (fr) * 1978-01-20 1980-06-06 Ile De France Nouveaux benzamides heterocycliques substitues, leurs procedes de preparation et leur application comme modificateurs du comportement
NZ199080A (en) * 1980-12-12 1984-07-31 Beecham Group Ltd 2-alkoxy-4-amino-5-alkylsulphonyl-n-(3beta-(8-hydrocarbyl-8-azabicyclo (3,2,1)octyl))benzamides
FR2550447B1 (fr) * 1983-08-10 1986-01-17 Ile De France Application du n-(ally-2-pyrrolidinylmethyl) 2-methoxy 4-amino 5-methylsulfamoyl benzamide comme antiagregant plaquettaire
FR2574795B1 (fr) * 1984-12-18 1987-11-20 Ile De France Nouveau procede industriel de synthese du n-((1'-allyl 2'-pyrrolidinyl) methyl) 2-methoxy 4,5-azimido benzamide
FR2584401B1 (fr) * 1985-07-04 1987-11-20 Ile De France Nouveau benzamide, son procede de preparation et son application dans le domaine therapeutique
US5227388A (en) * 1989-12-26 1993-07-13 Hoechst-Roussel Pharmaceuticals Incorporated Thienobenzoxepins and naphthothiophenes
US5260319A (en) * 1989-12-26 1993-11-09 Hoechst-Roussel Pharmaceuticals Incorporated Thienobenzoxepins and naphthothiophenes
FR2678266A1 (fr) * 1991-06-28 1992-12-31 Delagrange Laboratoires Nouveaux derives de 2-hydroxy 4-amino 5-ethylsulfonyl benzamide utiles comme anxiolytiques.
FR2699533A1 (fr) * 1992-12-21 1994-06-24 Mouhtaram Mohamed Dérivés de N-((1,4-dialkyl-6-arylpipérazine-2-yl)méthyl)benzamides. (Isomères cis et trans) Propriétés pharmacologiques et applications.
FR2753376B1 (fr) * 1996-09-18 1998-10-16 Synthelabo Compositions pharmaceutiques comprenant de l'amisulpride et leurs applications therapeutiques
FR2762213B1 (fr) * 1997-04-18 1999-05-14 Synthelabo Composition pharmaceutique a retention gastrique
US6169094B1 (en) * 1998-07-14 2001-01-02 Sanofi-Synthelabo Compositions of (S) (-)-amisulpride
AU2002322720B2 (en) 2001-07-25 2008-11-13 Raptor Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
EP1633400A2 (en) * 2003-05-16 2006-03-15 Pfizer Products Inc. Therapeutic combinations of atypical antipsychotics with gaba modulators, anticonvulsants or benzodiazapines
FR2857263B1 (fr) * 2003-07-09 2005-09-09 Sanofi Synthelabo Nouvelle composition pharmaceutique solide comprenant de l'amisulpride
EP1753460A2 (en) * 2004-05-11 2007-02-21 Pfizer Products Inc. Combination of atypical antipsychotics and 5-ht1b receptor antagonists
PE20061318A1 (es) * 2005-04-22 2006-12-28 Wyeth Corp Nuevas combinaciones terapeuticas para el tratamiento o la prevencion de trastornos psicoticos
CN102379684B (zh) 2005-04-28 2014-11-19 普罗透斯数字保健公司 药物信息系统
KR20090071598A (ko) 2006-09-18 2009-07-01 랩터 파마슈티컬 인코포레이티드 수용체 결합 단백질(rap)-접합체 투여에 의한 간 질환의 치료
US7825156B2 (en) * 2007-02-02 2010-11-02 Copharms Method of treating bipolar depression with a benzamide derivative
EP2321011A1 (en) * 2008-06-25 2011-05-18 Pfizer Inc. Diaryl compounds and uses thereof
US20100105755A1 (en) * 2008-09-12 2010-04-29 Auspex Pharmaceuticals, Inc. Substituted benzamide modulators of dopamine receptor
EP2398500B1 (en) 2009-02-20 2019-03-13 2-BBB Medicines B.V. Glutathione-based drug delivery system
ES2942923T3 (es) 2009-05-06 2023-06-07 Laboratory Skin Care Inc Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas
CN101898991B (zh) * 2009-05-31 2013-09-25 江苏天士力帝益药业有限公司 一种(s)(-)-氨磺必利d-(-)-酒石酸盐的合成方法
CN101628886B (zh) * 2009-08-25 2012-12-12 北京紫萌同达科技有限公司 一种2-甲氧基-4-氨基-5-乙砜基苯甲酸的合成方法
AU2016216578B2 (en) * 2010-03-11 2017-11-23 Acacia Pharma Limited The use of amisulpride as an anti-emetic
AU2014202535B2 (en) * 2010-03-11 2016-05-26 Acacia Pharma Limited The use of amisulpride as an anti-emetic
GB201004020D0 (en) * 2010-03-11 2010-04-21 Acacia Pharma Ltd New therapeutic use
BR112012031959A2 (pt) 2010-06-17 2015-09-22 Lupin Ltd um processo aperfeiçoado para preparação de amisulpride
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
CN103304453A (zh) * 2013-06-18 2013-09-18 苏州诚和医药化学有限公司 两步法合成2-甲氧基-4-氨基-5-乙砜基苯甲酸
CN103319384A (zh) * 2013-06-18 2013-09-25 苏州诚和医药化学有限公司 制备2-甲氧基-4-氨基-5-乙砜基苯甲酸的方法
CN103450058B (zh) * 2013-09-18 2015-10-14 广安凯特医药化工有限公司 一种氨磺必利酸的制备方法
CN104725292B (zh) * 2015-03-23 2017-07-25 湖北荆江源制药股份有限公司 一种(s)(‑)‑氨磺必利的制备方法
GB201618425D0 (en) * 2016-11-01 2016-12-14 Acacia Pharma Ltd method
US11377421B2 (en) 2016-11-28 2022-07-05 Lb Pharmaceuticals Inc. Psychotropic agents and uses thereof
MA46901A (fr) * 2016-11-28 2019-10-02 Lb Pharmaceuticals Inc Agents psychotropes et leurs utilisations
CN106995397B (zh) * 2016-12-12 2020-01-14 河北医科大学 R-氨磺必利药用盐、制备方法、晶型及其用途
GB201702250D0 (en) 2017-02-10 2017-03-29 Acacia Pharma Ltd Method
CN118593482A (zh) 2017-12-05 2024-09-06 赛诺维信制药公司 非外消旋混合物及其用途
WO2019113084A1 (en) 2017-12-05 2019-06-13 Sunovion Pharmaceuticals Inc. Crystal forms and production methods thereof
CN110790693A (zh) * 2018-08-02 2020-02-14 北京万全德众医药生物技术有限公司 一种(s)(-)-氨磺必利的制备方法
MX2021014774A (es) 2019-06-04 2022-02-03 Sunovion Pharmaceuticals Inc Formulaciones de liberacion modificada y usos de las mismas.
USD1047552S1 (en) * 2021-04-23 2024-10-22 Krueger International, Inc. Furniture leg with frame
CN116003304A (zh) * 2023-02-08 2023-04-25 浙江皓华制药有限公司 一种氨磺必利的合成方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3342826A (en) * 1964-01-13 1967-09-19 Ile De France Heterocyclic aminoalkyl benzamides
FR2313935A1 (fr) * 1975-06-10 1977-01-07 Ile De France Nouveaux benzamides substitues, leurs derives et leur procede de preparation
US3862139A (en) * 1972-06-23 1975-01-21 Delmar Chem Heterocyclic benzamide compounds
FR2244760B1 (it) * 1973-09-25 1980-06-27 Ile De France
FR2299862B1 (en) * 1975-02-07 1978-07-21 Soc Et Scient Et Ind Substd. N-(1-benzylpyrrolidinyl-2-alkyl)benzamides - used as antiemetics, anti-ulcer agents and CNS active
FR2294698A1 (fr) * 1974-12-18 1976-07-16 Synthelabo Nouveaux derives des methoxy-2 benzamides substitues, leurs sels, leur preparation et les medicaments qui en renferment
SE412908B (sv) * 1974-12-18 1980-03-24 Synthelabo Forfarande for framstellning av terapeutiskt aktiva 2-metoxibensamider innehallande en pyrrolidin- eller en piperidinrest

Also Published As

Publication number Publication date
BE872585A (fr) 1979-06-07
BG31497A3 (bg) 1982-01-15
BG31496A3 (bg) 1982-01-15
JPS6049192B2 (ja) 1985-10-31
SE460968B (sv) 1989-12-11
FI71126C (fi) 1986-11-24
IL56411A (en) 1982-09-30
US4401822A (en) 1983-08-30
RO80311A (ro) 1982-12-06
GB2083458A (en) 1982-03-24
AR220574A1 (es) 1980-11-14
NZ189378A (en) 1983-03-15
ES477782A1 (es) 1979-09-16
SE8603773D0 (sv) 1986-09-09
DE2901181A1 (de) 1979-07-26
DK20979A (da) 1979-07-21
YU41278B (en) 1986-12-31
HU179793B (en) 1982-12-28
OA06156A (fr) 1981-06-30
ATA39879A (de) 1983-12-15
PH15725A (en) 1983-03-18
ES476755A1 (es) 1979-06-01
HK12184A (en) 1984-02-24
YU25483A (en) 1983-10-31
ZM579A1 (en) 1979-12-21
SE448874B (sv) 1987-03-23
NL7900457A (nl) 1979-07-24
EG14045A (en) 1983-09-30
IE47798B1 (en) 1984-06-27
DK158346B (da) 1990-05-07
FR2415099A1 (fr) 1979-08-17
AU4337379A (en) 1979-07-26
FR2415099B1 (it) 1981-02-20
AT377977B (de) 1985-05-28
CH637927A5 (fr) 1983-08-31
MX7623E (es) 1990-03-27
PT69068A (fr) 1979-02-01
NO151320B (no) 1984-12-10
NL191707B (nl) 1995-12-01
US4294828A (en) 1981-10-13
FI790182A7 (fi) 1979-07-21
NO151320C (no) 1985-04-17
GR64431B (en) 1980-03-21
NL191707C (nl) 1996-04-02
MX5793E (es) 1984-07-19
YU5079A (en) 1983-06-30
DE2901181C2 (de) 1984-07-19
CY1201A (en) 1983-12-31
ZA79219B (en) 1980-01-30
DK158346C (da) 1990-10-08
RO76393A (ro) 1981-03-30
SE8603773L (sv) 1986-09-09
SE7900380L (sv) 1979-07-21
IL56411A0 (en) 1979-03-12
CS226181B2 (en) 1984-03-19
DD141520A5 (de) 1980-05-07
IN150226B (it) 1982-08-21
NO790180L (no) 1979-07-23
LU80786A1 (fr) 1979-09-07
GB2083458B (en) 1983-03-09
PL212899A1 (it) 1980-01-14
GB2012765A (en) 1979-08-01
MC1232A1 (fr) 1979-10-26
FI71126B (fi) 1986-08-14
SU820659A3 (ru) 1981-04-07
PH22287A (en) 1988-07-22
IE790092L (en) 1979-07-20
JPS54145658A (en) 1979-11-14
PL118151B1 (en) 1981-09-30
YU42172B (en) 1988-06-30
IT1164655B (it) 1987-04-15
PL116532B1 (en) 1981-06-30
GB2012765B (en) 1982-09-08
AR221354A1 (es) 1981-01-30
AU528561B2 (en) 1983-05-05
CA1101430A (en) 1981-05-19

Similar Documents

Publication Publication Date Title
IT1164655B (it) Derivati originali di 4-ammino-5-alchilsolfonil orto-anisammidi procedimento per la loro produzione e loro impiego come agenti psicotropici
IT1119284B (it) Derivati carbostirilici e procedimento per la loro preparazione
IT7967023A0 (it) Derivati di prostaciclina e procedimento per la loro preparazione
IT1117782B (it) Derivati mercaptoacilici di proline sostituite e procedimento per la loro preparazione
IT1121273B (it) Derivati analoghi di cefalosporina e procedimenti per la loro preparazione
IT1093805B (it) Derivati del 2h-benzofuran-3-one e procedimento per la loro preparazione
IT1123120B (it) Cefem derivati e procedimento per la loro preparazione
IT1164735B (it) Derivati adenosinici e procedimento per la loro preparazione
IT1121483B (it) Derivati di benzotiepinici e procedimento per la loro preparazione
IT7820957A0 (it) Derivati di acido 1-azaxantone-3-carbossilico eprocedimento per la loro preparazione.
IT7852471A0 (it) Derivati di 2-amminometil-fenolo eprocedimento per la loro preparazione
IT1122391B (it) Derivati di idrochinone e relativo procedimento per la loro produzione
IT1113203B (it) Derivati steroideo-spiro-ossazolidinonici sostituiti e procedimento per la loro preparazione
IT1109653B (it) Derivati del tetraidro 1 3 5 tiadiazin 4 one particolarmente utili come insetticidi e procedimento per la loro preparazione
IT1109002B (it) Derivati del 2 oxazolidone e loro metodi di preparazione
IT1120407B (it) Procedimento per la preparazione di derivati di pirrolidincarbossaldeide e piperidincarbossaldeide e prodotto ottenuto
IT1163698B (it) Derivati di 1-ftalazone, procedimento per la loro preparazione, e loro impiego
IT8024151A0 (it) Derivati di 10-alo-e-omoeburnano eprocedimento per la loro preparazione.
IT1092408B (it) Procedimento per la produzione di derivati dell'indolina
IT1099996B (it) Derivati del 4,5-difenil-ossazolo 2-ammino o 2-tio sostituiti e procedimento per il loro ottenimento
IT7850349A0 (it) Derivati di 1/2/4-triazinone utili come diserbanti e procedimento per la loro produzione
IT1075571B (it) Processo per la preparazione di butendioldiesteri e loro derivati
IT1162424B (it) Derivati di 7 alfa-metossicefalosporina e procedimento per produrli
IT7968397A0 (it) Derivati di cefalosporine partico larmente utili come microbicidi eprocedimento per la loro preparazione
IT1148788B (it) Derivati dell'amminoisochinolina e procedimento per la loro preparazione

Legal Events

Date Code Title Description
ITCP Complementary protection certificate

Free format text: CCP 466

MEDD Supplementary protection certificate for pharmaceutical products: granted

Free format text: CCP 466, 19930701; SYNTHELABO

TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19950125