ITTO991009A0 - Antagonisti iii del recettore ccr-3. - Google Patents
Antagonisti iii del recettore ccr-3.Info
- Publication number
- ITTO991009A0 ITTO991009A0 IT99TO001009A ITTO991009A ITTO991009A0 IT TO991009 A0 ITTO991009 A0 IT TO991009A0 IT 99TO001009 A IT99TO001009 A IT 99TO001009A IT TO991009 A ITTO991009 A IT TO991009A IT TO991009 A0 ITTO991009 A0 IT TO991009A0
- Authority
- IT
- Italy
- Prior art keywords
- ccr
- receptor antagonists
- iii
- antagonists iii
- receptor
- Prior art date
Links
- 102000004499 CCR3 Receptors Human genes 0.000 title 1
- 108010017316 CCR3 Receptors Proteins 0.000 title 1
- 239000002464 receptor antagonist Substances 0.000 title 1
- 229940044551 receptor antagonist Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10929798P | 1998-11-20 | 1998-11-20 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITTO991009A0 true ITTO991009A0 (it) | 1999-11-19 |
| ITTO991009A1 ITTO991009A1 (it) | 2001-05-19 |
| IT1307900B1 IT1307900B1 (it) | 2001-11-19 |
Family
ID=22326918
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT1999TO001009A IT1307900B1 (it) | 1998-11-20 | 1999-11-19 | Antagonisti iii del recettore ccr-3. |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US6166015A (it) |
| EP (1) | EP1131288A1 (it) |
| JP (1) | JP3593037B2 (it) |
| KR (1) | KR20010086045A (it) |
| CN (1) | CN1158256C (it) |
| AR (1) | AR023707A1 (it) |
| AU (1) | AU763960B2 (it) |
| BR (1) | BR9915520A (it) |
| CA (1) | CA2350903A1 (it) |
| CO (1) | CO5140119A1 (it) |
| CZ (1) | CZ20011760A3 (it) |
| DE (1) | DE19955794A1 (it) |
| ES (1) | ES2158814B1 (it) |
| FR (1) | FR2786185A1 (it) |
| GB (1) | GB2343893B (it) |
| HU (1) | HUP0104364A2 (it) |
| ID (1) | ID29067A (it) |
| IL (1) | IL143226A0 (it) |
| IT (1) | IT1307900B1 (it) |
| MA (1) | MA26762A1 (it) |
| NO (1) | NO20012411D0 (it) |
| PE (1) | PE20001403A1 (it) |
| PL (1) | PL348375A1 (it) |
| TR (1) | TR200101398T2 (it) |
| UY (1) | UY25811A1 (it) |
| WO (1) | WO2000031032A1 (it) |
| ZA (1) | ZA200103942B (it) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL125658A0 (en) | 1997-08-18 | 1999-04-11 | Hoffmann La Roche | Ccr-3 receptor antagonists |
| US6339087B1 (en) | 1997-08-18 | 2002-01-15 | Syntex (U.S.A.) Llc | Cyclic amine derivatives-CCR-3 receptor antagonists |
| US6316623B1 (en) * | 1998-08-21 | 2001-11-13 | Isis Pharmaceuticals, Inc. | Ethylenediamine compound libraries |
| WO2000031033A1 (en) | 1998-11-20 | 2000-06-02 | F. Hoffmann-La Roche Ag | Piperidine ccr-3 receptor antagonists |
| DE60023878T2 (de) * | 1999-05-18 | 2006-07-20 | Teijin Ltd. | Heilmittel und vorbeugung für mit chemokinen verbundenen erkrankungen |
| WO2001010439A1 (en) * | 1999-08-04 | 2001-02-15 | Teijin Limited | Cyclic amine ccr3 antagonists |
| CA2393757C (en) * | 1999-12-08 | 2009-04-07 | Teijin Limited | Cycloamine ccr5 receptor antagonists |
| CA2423305A1 (en) * | 2000-09-29 | 2002-04-04 | Glaxo Group Limited | Compounds useful in the treatment of inflammatory diseases |
| CA2423251A1 (en) | 2000-09-29 | 2002-04-04 | Glaxo Group Limited | Morpholin-acetamide derivatives for the treatment of inflammatory diseases |
| AU2002216107A1 (en) | 2000-12-19 | 2002-07-01 | F. Hoffmann-La Roche Ag | Substituted pyrrolidines as CCR-3 receptor antagonists |
| FR2821356A1 (fr) * | 2001-02-23 | 2002-08-30 | Cerep | Nouveaux derives d'arylcarbamates et d'arylurees, preparations et utilisations |
| GB0117387D0 (en) * | 2001-07-17 | 2001-09-05 | Novartis Ag | Organic compounds |
| BR0212451A (pt) * | 2001-09-13 | 2004-10-19 | Hoffmann La Roche | Antagonistas de receptores de ccr-3 v |
| US7067549B2 (en) * | 2001-12-31 | 2006-06-27 | Actelion Pharmaceuticals Ag | Pyrrolidone carboxamides |
| GB0207443D0 (en) * | 2002-03-28 | 2002-05-08 | Glaxo Group Ltd | Novel compounds |
| GB0207432D0 (en) * | 2002-03-28 | 2002-05-08 | Glaxo Group Ltd | Novel compounds |
| GB0207439D0 (en) * | 2002-03-28 | 2002-05-08 | Glaxo Group Ltd | Novel compounds |
| GB0207436D0 (en) * | 2002-03-28 | 2002-05-08 | Glaxo Group Ltd | Novel compounds |
| GB0212355D0 (en) * | 2002-05-29 | 2002-07-10 | Glaxo Group Ltd | Novel compounds |
| CA2488202C (en) | 2002-06-12 | 2011-03-08 | Chemocentryx, Inc. | 1-aryl-4-substituted piperazine derivatives for use as ccr1 antagonists for the treatment of inflammation and immune disorders |
| US7842693B2 (en) | 2002-06-12 | 2010-11-30 | Chemocentryx, Inc. | Substituted piperazines |
| US7589199B2 (en) | 2002-06-12 | 2009-09-15 | Chemocentryx, Inc. | Substituted piperazines |
| CA2490148A1 (en) | 2002-07-02 | 2004-01-15 | F. Hoffmann-La Roche Ag | 2, 5-substituted pyrimidine derivatives as ccr-3 receptor antagonists ix |
| US6919356B2 (en) * | 2002-09-26 | 2005-07-19 | Bristol Myers Squibb Company | N-substituted heterocyclic amines as modulators of chemokine receptor activity |
| WO2004078749A1 (en) | 2003-03-06 | 2004-09-16 | Glaxo Group Limited | Heterocyclic urea derivatives for the treatment of pain |
| US7514562B2 (en) | 2003-03-07 | 2009-04-07 | Glaxo Group Limited | Urea derivatives and their use as vanilloid receptor antagonists in the treatment of pain |
| GB0305426D0 (en) * | 2003-03-08 | 2003-04-16 | Glaxo Group Ltd | Novel compounds |
| JP4736043B2 (ja) | 2003-03-14 | 2011-07-27 | 小野薬品工業株式会社 | 含窒素複素環誘導体およびそれらを有効成分とする薬剤 |
| JP4710606B2 (ja) | 2003-04-18 | 2011-06-29 | 小野薬品工業株式会社 | スピロピペリジン化合物およびその医薬用途 |
| SG131946A1 (en) * | 2003-10-24 | 2007-05-28 | Hoffmann La Roche | Ccr3 receptor antagonists |
| JP4845873B2 (ja) | 2004-03-03 | 2011-12-28 | ケモセントリックス インコーポレーティッド | 二環式および架橋した窒素複素環 |
| US7435831B2 (en) | 2004-03-03 | 2008-10-14 | Chemocentryx, Inc. | Bicyclic and bridged nitrogen heterocycles |
| NZ551196A (en) * | 2004-05-14 | 2010-08-27 | Emisphere Tech Inc | Compounds and compositions for delivering active agents |
| RU2530889C2 (ru) * | 2004-05-14 | 2014-10-20 | Эмисфире Текнолоджис, Инк. | Соединения и составы для доставки активных веществ |
| KR101231466B1 (ko) | 2004-09-13 | 2013-02-07 | 오노 야꾸힝 고교 가부시키가이샤 | 질소 함유 복소환 유도체 및 이들을 유효 성분으로 하는약제 |
| WO2006088541A2 (en) * | 2005-02-17 | 2006-08-24 | State Of Oregon Acting By & Through The State Board Of Higher Edu. On Behalf Of Portland State Unv. | Quinoline derivatives and uses thereof |
| EP1889622A4 (en) | 2005-05-31 | 2009-12-23 | Ono Pharmaceutical Co | SPIROPIPERIDINE COMPOUND AND MEDICINAL USE THEREOF |
| US20090118288A1 (en) * | 2005-07-21 | 2009-05-07 | Astrazeneca Ab | N-Benzyl-Morpholine Derivatives as Modulators of the Chemokine Receptor |
| JP2009507783A (ja) * | 2005-08-25 | 2009-02-26 | アールエステック コーポレイション | 高光学純度を有するキラル３−ヒドロキシピロリジン化合物及びその誘導体の製造方法 |
| HUP0500879A2 (en) * | 2005-09-22 | 2007-05-29 | Sanofi Aventis | Amide derivatives as ccr3 receptor ligands, process for producing them, pharmaceutical compositions containing them and their use and intermediates |
| CA2623317A1 (en) * | 2005-09-22 | 2007-03-29 | Sanofi-Aventis | Amino-alkyl-amide derivatives as ccr3 receptor liquids |
| HUP0500877A2 (en) * | 2005-09-22 | 2007-05-29 | Sanofi Aventis | Amide derivatives as ccr3 receptor ligands, process for producing them, pharmaceutical compositions containing them and their use and intermediates |
| HUP0500886A2 (en) * | 2005-09-23 | 2007-05-29 | Sanofi Aventis | Amide derivatives as ccr3 receptor ligands, process for producing them, pharmaceutical compositions containing them and their use |
| ES2427989T3 (es) | 2005-10-28 | 2013-11-05 | Ono Pharmaceutical Co., Ltd. | Compuesto que contiene un grupo básico y uso del mismo |
| WO2007058322A1 (ja) | 2005-11-18 | 2007-05-24 | Ono Pharmaceutical Co., Ltd. | 塩基性基を含有する化合物およびその用途 |
| JPWO2007105637A1 (ja) | 2006-03-10 | 2009-07-30 | 小野薬品工業株式会社 | 含窒素複素環誘導体およびそれらを有効成分とする薬剤 |
| WO2007132846A1 (ja) | 2006-05-16 | 2007-11-22 | Ono Pharmaceutical Co., Ltd. | 保護されていてもよい酸性基を含有する化合物およびその用途 |
| WO2008016006A1 (fr) | 2006-07-31 | 2008-02-07 | Ono Pharmaceutical Co., Ltd. | Composé auquel un groupe cyclique est lié par une liaison spiro et son utilisation |
| WO2010129351A1 (en) | 2009-04-28 | 2010-11-11 | Schepens Eye Research Institute | Method to identify and treat age-related macular degeneration |
| CN101906060B (zh) * | 2010-05-06 | 2012-07-04 | 爱斯医药科技(南京)有限公司 | N-取代的3-氨甲基吡咯烷的制备方法 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3459757A (en) * | 1965-10-22 | 1969-08-05 | American Cyanamid Co | Imidazolidines |
| NZ186175A (en) * | 1977-01-27 | 1980-03-05 | Shionogi & Co | Meta-sulphonamidobenzamide derivatives |
| JPS59186969A (ja) * | 1983-04-08 | 1984-10-23 | Yoshitomi Pharmaceut Ind Ltd | ベンゾフラン−およびベンゾピランカルボキサミド誘導体 |
| FI95572C (fi) * | 1987-06-22 | 1996-02-26 | Eisai Co Ltd | Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi |
| JPH01117860A (ja) * | 1987-10-30 | 1989-05-10 | Dainippon Pharmaceut Co Ltd | 安息香酸アミド誘導体 |
| JPH02104572A (ja) * | 1988-10-13 | 1990-04-17 | Dainippon Pharmaceut Co Ltd | 安息香酸アミド誘導体 |
| US5214055A (en) * | 1990-05-18 | 1993-05-25 | Adir Et Compagnie | Aminopiperidine 4-oxo-4H-chromen-2-yl compounds |
| FR2662162B1 (fr) * | 1990-05-18 | 1995-01-20 | Adir | Nouveaux derives de l'amino piperidine, de l'amino pyrrolidine et de l'amino perhydroazepine, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent. |
| US5254569A (en) * | 1991-01-14 | 1993-10-19 | The Du Pont Merck Pharmaceutical Company | (Amidomethyl)nitrogen heterocyclic analgesics |
| GB9113031D0 (en) * | 1991-06-17 | 1991-08-07 | Smithkline Beecham Plc | Compounds |
| FR2679906B1 (fr) * | 1991-07-31 | 1995-01-20 | Adir | Nouvelles (isoquinolein-5 yl) sulfonamides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| AU2435092A (en) * | 1991-08-20 | 1993-03-16 | Smithkline Beecham Plc | 5-ht4 receptor antagonists |
| JPH06212757A (ja) * | 1993-01-19 | 1994-08-02 | Ribaa Kentetsu Kk | ソリ型運搬治具による折板屋根葺き工法 |
| EP0742208A1 (en) * | 1995-05-05 | 1996-11-13 | Grelan Pharmaceutical Co., Ltd. | 2-Ureido-benzamide derivatives |
| US5827875A (en) * | 1996-05-10 | 1998-10-27 | Bristol-Myers Squibb Company | Inhibitors of microsomal triglyceride transfer protein and method |
| AU3633997A (en) * | 1996-07-29 | 1998-02-20 | Banyu Pharmaceutical Co., Ltd. | Chemokine receptor antagonists |
| IL125658A0 (en) * | 1997-08-18 | 1999-04-11 | Hoffmann La Roche | Ccr-3 receptor antagonists |
| JPH11140276A (ja) * | 1997-11-11 | 1999-05-25 | Sumitomo Chem Co Ltd | 多官能シアン酸エステル樹脂組成物および樹脂封止型半導体装置 |
| EP1553085A1 (en) * | 1997-11-18 | 2005-07-13 | Teijin Limited | Cyclic amine derivatives and their use as drugs |
-
1999
- 1999-11-11 CN CNB99813287XA patent/CN1158256C/zh not_active Expired - Fee Related
- 1999-11-11 IL IL14322699A patent/IL143226A0/xx unknown
- 1999-11-11 WO PCT/EP1999/008665 patent/WO2000031032A1/en not_active Ceased
- 1999-11-11 ID IDW00200101080A patent/ID29067A/id unknown
- 1999-11-11 AU AU13825/00A patent/AU763960B2/en not_active Ceased
- 1999-11-11 JP JP2000583860A patent/JP3593037B2/ja not_active Expired - Fee Related
- 1999-11-11 HU HU0104364A patent/HUP0104364A2/hu unknown
- 1999-11-11 TR TR2001/01398T patent/TR200101398T2/xx unknown
- 1999-11-11 CA CA002350903A patent/CA2350903A1/en not_active Abandoned
- 1999-11-11 CZ CZ20011760A patent/CZ20011760A3/cs unknown
- 1999-11-11 PL PL99348375A patent/PL348375A1/xx not_active Application Discontinuation
- 1999-11-11 BR BR9915520-6A patent/BR9915520A/pt not_active IP Right Cessation
- 1999-11-11 KR KR1020017006362A patent/KR20010086045A/ko not_active Ceased
- 1999-11-11 EP EP99972623A patent/EP1131288A1/en not_active Withdrawn
- 1999-11-16 PE PE1999001161A patent/PE20001403A1/es not_active Application Discontinuation
- 1999-11-17 GB GB9927227A patent/GB2343893B/en not_active Expired - Fee Related
- 1999-11-18 CO CO99072639A patent/CO5140119A1/es unknown
- 1999-11-18 FR FR9914495A patent/FR2786185A1/fr not_active Withdrawn
- 1999-11-18 US US09/442,656 patent/US6166015A/en not_active Expired - Fee Related
- 1999-11-18 AR ARP990105860A patent/AR023707A1/es unknown
- 1999-11-19 DE DE19955794A patent/DE19955794A1/de not_active Withdrawn
- 1999-11-19 IT IT1999TO001009A patent/IT1307900B1/it active
- 1999-11-19 ES ES009902547A patent/ES2158814B1/es not_active Expired - Lifetime
- 1999-11-19 UY UY25811A patent/UY25811A1/es unknown
-
2001
- 2001-05-15 ZA ZA200103942A patent/ZA200103942B/en unknown
- 2001-05-16 NO NO20012411A patent/NO20012411D0/no not_active Application Discontinuation
- 2001-05-17 MA MA26199A patent/MA26762A1/fr unknown
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