JO3775B1 - جزيئات رابطة لليمفو بويتين اللحمية بالغدة الصعترية أو الثيمية (tslp) وطرق لاستخدام تلك الجزيئات - Google Patents

جزيئات رابطة لليمفو بويتين اللحمية بالغدة الصعترية أو الثيمية (tslp) وطرق لاستخدام تلك الجزيئات

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Publication number
JO3775B1
JO3775B1 JOP/2016/0200A JOP20160200A JO3775B1 JO 3775 B1 JO3775 B1 JO 3775B1 JO P20160200 A JOP20160200 A JO P20160200A JO 3775 B1 JO3775 B1 JO 3775B1
Authority
JO
Jordan
Prior art keywords
molecules
tslp
methods
thymic stromal
stromal lymphopoietin
Prior art date
Application number
JOP/2016/0200A
Other languages
English (en)
Inventor
John Edwards Matthew
Anselmus Van Heeke Gino
Huang Daniel
Haubst Nicole
Rene Rondeau Jean-Michel
Miller Dan
Gupta Kapil
Knopf Hans-Peter
Hemmig Rene
Andlauer Barbara
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Application granted granted Critical
Publication of JO3775B1 publication Critical patent/JO3775B1/ar

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    • C—CHEMISTRY; METALLURGY
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Otolaryngology (AREA)
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  • Genetics & Genomics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Endocrinology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
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  • Physiology (AREA)
  • Dispersion Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

يعمل هذا الاختراع على إعداد جزيئات على شكل شظيات من أجسام مضادة أو جسم مضاد، وإعداد تلك الشظيات التي تعمل بالتحديد على ربط الليمفوبويتين اللحمية بالغدة الصعترية TSLP، وكذا إعداد تركيبات متضمنة على تلك الجزيئات وطرق استخدام وانتاج تلك الجزيئات.
JOP/2016/0200A 2015-09-09 2016-09-08 جزيئات رابطة لليمفو بويتين اللحمية بالغدة الصعترية أو الثيمية (tslp) وطرق لاستخدام تلك الجزيئات JO3775B1 (ar)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562216050P 2015-09-09 2015-09-09
US201662342511P 2016-05-27 2016-05-27

Publications (1)

Publication Number Publication Date
JO3775B1 true JO3775B1 (ar) 2021-01-31

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JOP/2016/0200A JO3775B1 (ar) 2015-09-09 2016-09-08 جزيئات رابطة لليمفو بويتين اللحمية بالغدة الصعترية أو الثيمية (tslp) وطرق لاستخدام تلك الجزيئات

Country Status (30)

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US (2) US10745473B2 (ar)
EP (2) EP3347377B1 (ar)
JP (4) JP6516925B2 (ar)
KR (1) KR20180042433A (ar)
CN (2) CN114507281A (ar)
BR (1) BR112018003326A2 (ar)
CA (1) CA2996635A1 (ar)
CL (1) CL2018000479A1 (ar)
CR (1) CR20180154A (ar)
CU (1) CU24533B1 (ar)
CY (1) CY1124118T1 (ar)
DK (1) DK3347377T3 (ar)
EC (1) ECSP18023386A (ar)
ES (1) ES2869970T3 (ar)
HR (1) HRP20210650T1 (ar)
HU (1) HUE053914T2 (ar)
IL (1) IL257599A (ar)
JO (1) JO3775B1 (ar)
LT (1) LT3347377T (ar)
MA (1) MA55472A (ar)
MX (2) MX2018003038A (ar)
NZ (1) NZ740067A (ar)
PE (1) PE20181368A1 (ar)
PH (1) PH12018500482A1 (ar)
PL (1) PL3347377T3 (ar)
PT (1) PT3347377T (ar)
RS (1) RS61763B1 (ar)
RU (1) RU2731644C2 (ar)
SI (1) SI3347377T1 (ar)
TW (1) TWI746458B (ar)

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KR20180042433A (ko) * 2015-09-09 2018-04-25 노파르티스 아게 흉선 기질 림포포이에틴 (tslp)-결합 항체 및 항체의 사용 방법
WO2020071448A1 (ja) * 2018-10-02 2020-04-09 学校法人名城大学 吸入粉末剤、その評価方法及びその用途
WO2020079185A1 (en) * 2018-10-18 2020-04-23 Deutsches Krebsforschungszentrum Dry pharmaceutical composition for inhalation
CN114401741A (zh) * 2019-07-11 2022-04-26 拓维创新生物科技(香港)有限公司 干扰胸腺基质淋巴细胞生成素(tslp)受体信号传导的药剂
JP7331298B2 (ja) * 2019-09-04 2023-08-23 ビオシオン インコーポレイテッド 抗体結合ｔｓｌｐ及びその使用
RS66646B1 (sr) * 2019-10-28 2025-04-30 Medimmune Ltd Formulacije suvog praška vezujućih antitela za timusni stromalni limfopoetin (tslp) i postupci njihove upotrebe
CN114887053B (zh) * 2019-11-29 2026-04-24 康诺亚生物医药科技（成都）有限公司 一种tslp相关病症治疗剂的开发和应用
CA3155759A1 (en) * 2019-12-13 2021-06-17 Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. Anti-tslp antibody and uses thereof
CN115397394A (zh) * 2020-01-31 2022-11-25 赛诺菲 抗体的肺部递送
CN111171150B (zh) * 2020-02-05 2020-12-08 北京智仁美博生物科技有限公司 抗人tslp抗体及其用途
CN113388035B (zh) * 2020-03-13 2026-02-27 迈威(上海)生物科技股份有限公司 特异性针对人tslp的抗体及其应用
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ECSP18023386A (es) 2018-04-30
US10745473B2 (en) 2020-08-18
BR112018003326A2 (pt) 2018-09-18
CN108350070A (zh) 2018-07-31
PL3347377T3 (pl) 2021-07-19
DK3347377T3 (da) 2021-05-10
EP3347377B1 (en) 2021-02-17
RU2018112243A (ru) 2019-10-10
CL2018000479A1 (es) 2018-11-23
RS61763B1 (sr) 2021-05-31
HRP20210650T1 (hr) 2021-05-28
CN108350070B (zh) 2022-01-28
ES2869970T3 (es) 2021-10-26
SI3347377T1 (sl) 2021-06-30
LT3347377T (lt) 2021-05-25
CA2996635A1 (en) 2017-03-16

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