JP2004507501A - ベンジリデンチアゾリジンジオンおよび抗真菌剤としてのそれらの使用 - Google Patents

ベンジリデンチアゾリジンジオンおよび抗真菌剤としてのそれらの使用 Download PDF

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Publication number
JP2004507501A
JP2004507501A JP2002522888A JP2002522888A JP2004507501A JP 2004507501 A JP2004507501 A JP 2004507501A JP 2002522888 A JP2002522888 A JP 2002522888A JP 2002522888 A JP2002522888 A JP 2002522888A JP 2004507501 A JP2004507501 A JP 2004507501A
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JP
Japan
Prior art keywords
phenyl
branched
phenylmethoxy
methylene
oxo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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JP2002522888A
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English (en)
Japanese (ja)
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JP2004507501A5 (2
Inventor
マイケル・グレン・オーチャード
ジュディ・シャーロット・ノイス
カール・モーリス・スウェドラー・ギャリー
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Oxford Glycosciences UK Ltd
Original Assignee
Oxford Glycosciences UK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oxford Glycosciences UK Ltd filed Critical Oxford Glycosciences UK Ltd
Publication of JP2004507501A publication Critical patent/JP2004507501A/ja
Publication of JP2004507501A5 publication Critical patent/JP2004507501A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
JP2002522888A 2000-08-31 2001-08-30 ベンジリデンチアゾリジンジオンおよび抗真菌剤としてのそれらの使用 Pending JP2004507501A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0021421.3A GB0021421D0 (en) 2000-08-31 2000-08-31 Compounds
PCT/GB2001/003862 WO2002017915A1 (en) 2000-08-31 2001-08-30 Benzylidene thiazolidinediones and their use as antimycotic agents

Publications (2)

Publication Number Publication Date
JP2004507501A true JP2004507501A (ja) 2004-03-11
JP2004507501A5 JP2004507501A5 (2) 2005-04-14

Family

ID=9898616

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002522888A Pending JP2004507501A (ja) 2000-08-31 2001-08-30 ベンジリデンチアゾリジンジオンおよび抗真菌剤としてのそれらの使用

Country Status (9)

Country Link
US (1) US7105554B2 (2)
EP (1) EP1313471B1 (2)
JP (1) JP2004507501A (2)
AT (1) ATE359073T1 (2)
AU (1) AU2001284190A1 (2)
DE (1) DE60127845T2 (2)
ES (1) ES2282283T3 (2)
GB (1) GB0021421D0 (2)
WO (1) WO2002017915A1 (2)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011520968A (ja) * 2008-05-20 2011-07-21 メルク・シャープ・エンド・ドーム・コーポレイション マンノシルトランスフェラーゼ阻害剤を使用した異種蛋白質の効率的生産
WO2014024897A1 (ja) * 2012-08-06 2014-02-13 Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 チアゾリジンジオンおよびピロリジンジオン誘導体、並びにそれらを有効成分としてなる殺菌剤

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0204252D0 (en) * 2002-02-23 2002-04-10 Oxford Glycosciences Uk Ltd Novel compounds
WO2003070238A1 (en) * 2002-02-23 2003-08-28 Oxford Glycosciences (Uk) Ltd Thiazolidine antifungal agents
EP1730103B1 (en) 2004-03-23 2010-05-26 Pfizer Limited Formamide derivatives useful as adrenoceptor
EP1954815B1 (en) * 2005-11-15 2015-02-25 GlycoFi, Inc. Production of glycoproteins with reduced o-glycosylation
WO2007079466A2 (en) * 2006-01-04 2007-07-12 Nano Mist International, Llc Air driven delivery system for sprayable media
US8637435B2 (en) * 2007-11-16 2014-01-28 Merck Sharp & Dohme Corp. Eukaryotic cell display systems
CA2715212A1 (en) 2008-03-03 2009-09-11 Glycofi, Inc. Surface display of recombinant proteins in lower eukaryotes
US8067339B2 (en) 2008-07-09 2011-11-29 Merck Sharp & Dohme Corp. Surface display of whole antibodies in eukaryotes
CA2733567A1 (en) 2008-08-12 2010-02-18 Glycofi, Inc. Improved vectors and yeast strains for protein production: ca2+ atpase overexpression
KR20140114278A (ko) 2011-02-25 2014-09-26 머크 샤프 앤드 돔 코포레이션 변형된 ｏ-글리코실화를 갖는 단백질의 생산을 위한 효모 균주
CN103797000B (zh) * 2011-07-29 2016-07-06 大正制药株式会社 脒化合物或其盐
US9261497B2 (en) 2012-10-16 2016-02-16 New York University Method of treating cancer with modulators of SCFSkp2
ES2739280T3 (es) 2013-07-04 2020-01-30 Glykos Finland Oy Células fúngicas filamentosas deficientes en O-manosiltransferasa y métodos de uso de las mismas
SG11201700446XA (en) 2014-07-21 2017-02-27 Glykos Finland Oy Production of glycoproteins with mammalian-like n-glycans in filamentous fungi
CN109414432B (zh) * 2016-06-14 2022-03-08 港大科桥有限公司 抗微生物化合物及其使用方法
US10647654B2 (en) 2016-06-24 2020-05-12 Ohio University Glucose transport inhibitors and methods of using same
RU2662153C1 (ru) * 2017-04-20 2018-07-24 Общество С Ограниченной Ответственностью "Дермавитал Групп" Гибридные эфиры на основе производных тиазолидин-2,4-диона и азолов (1н-1,3-имидазола и 1н-1,3,4-триазола) и их применение
RU2690161C1 (ru) * 2018-06-28 2019-05-31 Общество С Ограниченной Ответственностью "Дермавитал Групп" 3,5-Замещенные производные тиазолидин-2,4-диона, обладающие противомикробной активностью
RU2703997C1 (ru) * 2018-12-13 2019-10-23 Общество с ограниченной ответственностью "Л-Био" Гибридные амиды на основе триазола и тиазолидина, обладающие антимикробной активностью
CN112521382A (zh) * 2020-12-14 2021-03-19 西南大学 芦荟大黄素噻唑烷二酮类化合物及其制备方法和应用
WO2024258316A1 (ru) * 2023-06-16 2024-12-19 Общество с ограниченной ответственностью "Л-Био" Новые потенциальные противогрибковые средства на основе тиазолидин-2,4-диона и триазола

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6156175A (ja) * 1984-08-24 1986-03-20 Yamanouchi Pharmaceut Co Ltd ロダニン誘導体およびその製造法
JPH06192091A (ja) * 1992-09-10 1994-07-12 Eli Lilly & Co 血糖低下用およびアルツハイマー病治療用化合物
WO1994029287A1 (de) * 1993-06-04 1994-12-22 Boehringer Mannheim Gmbh Aryliden-4-oxo-2-thioxo-3-thiazolidincarbonsäuren, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
JPH08109174A (ja) * 1994-10-07 1996-04-30 Torii Yakuhin Kk チアゾリジン−２−オン誘導体
JPH08109175A (ja) * 1994-10-07 1996-04-30 Torii Yakuhin Kk チアゾリジン−２−オンエステル誘導体
WO2000018747A1 (en) * 1998-09-30 2000-04-06 Roche Diagnostics Gmbh Rhodanine carboxylic acid derivatives for the treatment and prevention of metabolic bone disorders
WO2000018746A1 (en) * 1998-09-30 2000-04-06 Roche Diagnostics Gmbh Thiazolidine derivatives for the treatment and prevention of metabolic bone disorders
WO2001057006A1 (en) * 2000-02-03 2001-08-09 F. Hoffmann-La Roche Ag Thiazolidine carboxylic acid derivatives and their use in the treatment of cancer

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6156175A (ja) * 1984-08-24 1986-03-20 Yamanouchi Pharmaceut Co Ltd ロダニン誘導体およびその製造法
JPH06192091A (ja) * 1992-09-10 1994-07-12 Eli Lilly & Co 血糖低下用およびアルツハイマー病治療用化合物
WO1994029287A1 (de) * 1993-06-04 1994-12-22 Boehringer Mannheim Gmbh Aryliden-4-oxo-2-thioxo-3-thiazolidincarbonsäuren, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
JPH08109174A (ja) * 1994-10-07 1996-04-30 Torii Yakuhin Kk チアゾリジン−２−オン誘導体
JPH08109175A (ja) * 1994-10-07 1996-04-30 Torii Yakuhin Kk チアゾリジン−２−オンエステル誘導体
WO2000018747A1 (en) * 1998-09-30 2000-04-06 Roche Diagnostics Gmbh Rhodanine carboxylic acid derivatives for the treatment and prevention of metabolic bone disorders
WO2000018746A1 (en) * 1998-09-30 2000-04-06 Roche Diagnostics Gmbh Thiazolidine derivatives for the treatment and prevention of metabolic bone disorders
WO2001057006A1 (en) * 2000-02-03 2001-08-09 F. Hoffmann-La Roche Ag Thiazolidine carboxylic acid derivatives and their use in the treatment of cancer
JP2003521542A (ja) * 2000-02-03 2003-07-15 エフ．ホフマン−ラ ロシュ アーゲー チアゾリジンカルボン酸誘導体及び癌の治療におけるその利用

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011520968A (ja) * 2008-05-20 2011-07-21 メルク・シャープ・エンド・ドーム・コーポレイション マンノシルトランスフェラーゼ阻害剤を使用した異種蛋白質の効率的生産
WO2014024897A1 (ja) * 2012-08-06 2014-02-13 Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 チアゾリジンジオンおよびピロリジンジオン誘導体、並びにそれらを有効成分としてなる殺菌剤

Also Published As

Publication number Publication date
ES2282283T3 (es) 2007-10-16
US20040006112A1 (en) 2004-01-08
WO2002017915A1 (en) 2002-03-07
EP1313471A1 (en) 2003-05-28
DE60127845T2 (de) 2007-12-20
US7105554B2 (en) 2006-09-12
GB0021421D0 (en) 2000-10-18
AU2001284190A1 (en) 2002-03-13
EP1313471B1 (en) 2007-04-11
DE60127845D1 (de) 2007-05-24
ATE359073T1 (de) 2007-05-15

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