JP2016190870A5 - - Google Patents
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- JP2016190870A5 JP2016190870A5 JP2016152831A JP2016152831A JP2016190870A5 JP 2016190870 A5 JP2016190870 A5 JP 2016190870A5 JP 2016152831 A JP2016152831 A JP 2016152831A JP 2016152831 A JP2016152831 A JP 2016152831A JP 2016190870 A5 JP2016190870 A5 JP 2016190870A5
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Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8942208P | 2008-08-15 | 2008-08-15 | |
| US61/089,422 | 2008-08-15 | ||
| US27333209P | 2009-08-03 | 2009-08-03 | |
| US61/273,332 | 2009-08-03 | ||
| US23172509P | 2009-08-06 | 2009-08-06 | |
| US61/231,725 | 2009-08-06 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014092883A Division JP6034327B2 (ja) | 2008-08-15 | 2014-04-28 | 経口投与に好適なｇｃ−ｃ受容体アゴニストポリペプチドの安定な固体製剤 |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018070898A Division JP6473532B2 (ja) | 2008-08-15 | 2018-04-02 | 経口投与に好適なｇｃ−ｃ受容体アゴニストポリペプチドの安定な固体製剤 |
| JP2018070899A Division JP2018104469A (ja) | 2008-08-15 | 2018-04-02 | 経口投与に好適なｇｃ−ｃ受容体アゴニストポリペプチドの安定な固体製剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016190870A JP2016190870A (ja) | 2016-11-10 |
| JP2016190870A5 true JP2016190870A5 (ja) | 2017-03-30 |
Family
ID=41666602
Family Applications (10)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011523004A Active JP5770629B2 (ja) | 2008-08-15 | 2009-08-14 | 経口投与に好適なｇｃ−ｃ受容体アゴニストポリペプチドの安定な固体製剤 |
| JP2014092883A Active JP6034327B2 (ja) | 2008-08-15 | 2014-04-28 | 経口投与に好適なｇｃ−ｃ受容体アゴニストポリペプチドの安定な固体製剤 |
| JP2016152831A Withdrawn JP2016190870A (ja) | 2008-08-15 | 2016-08-03 | 経口投与に好適なｇｃ−ｃ受容体アゴニストポリペプチドの安定な固体製剤 |
| JP2018070899A Withdrawn JP2018104469A (ja) | 2008-08-15 | 2018-04-02 | 経口投与に好適なｇｃ−ｃ受容体アゴニストポリペプチドの安定な固体製剤 |
| JP2018070898A Active JP6473532B2 (ja) | 2008-08-15 | 2018-04-02 | 経口投与に好適なｇｃ−ｃ受容体アゴニストポリペプチドの安定な固体製剤 |
| JP2019126707A Withdrawn JP2019163340A (ja) | 2008-08-15 | 2019-07-08 | 経口投与に好適なｇｃ−ｃ受容体アゴニストポリペプチドの安定な固体製剤 |
| JP2021018125A Withdrawn JP2021073297A (ja) | 2008-08-15 | 2021-02-08 | 経口投与に好適なｇｃ−ｃ受容体アゴニストポリペプチドの安定な固体製剤 |
| JP2022111842A Withdrawn JP2022132383A (ja) | 2008-08-15 | 2022-07-12 | 経口投与に好適なｇｃ－ｃ受容体アゴニストポリペプチドの安定な固体製剤 |
| JP2023209257A Withdrawn JP2024015361A (ja) | 2008-08-15 | 2023-12-12 | 経口投与に好適なｇｃ－ｃ受容体アゴニストポリペプチドの安定な固体製剤 |
| JP2025080475A Pending JP2025109853A (ja) | 2008-08-15 | 2025-05-13 | 経口投与に好適なｇｃ－ｃ受容体アゴニストポリペプチドの安定な固体製剤 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011523004A Active JP5770629B2 (ja) | 2008-08-15 | 2009-08-14 | 経口投与に好適なｇｃ−ｃ受容体アゴニストポリペプチドの安定な固体製剤 |
| JP2014092883A Active JP6034327B2 (ja) | 2008-08-15 | 2014-04-28 | 経口投与に好適なｇｃ−ｃ受容体アゴニストポリペプチドの安定な固体製剤 |
Family Applications After (7)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018070899A Withdrawn JP2018104469A (ja) | 2008-08-15 | 2018-04-02 | 経口投与に好適なｇｃ−ｃ受容体アゴニストポリペプチドの安定な固体製剤 |
| JP2018070898A Active JP6473532B2 (ja) | 2008-08-15 | 2018-04-02 | 経口投与に好適なｇｃ−ｃ受容体アゴニストポリペプチドの安定な固体製剤 |
| JP2019126707A Withdrawn JP2019163340A (ja) | 2008-08-15 | 2019-07-08 | 経口投与に好適なｇｃ−ｃ受容体アゴニストポリペプチドの安定な固体製剤 |
| JP2021018125A Withdrawn JP2021073297A (ja) | 2008-08-15 | 2021-02-08 | 経口投与に好適なｇｃ−ｃ受容体アゴニストポリペプチドの安定な固体製剤 |
| JP2022111842A Withdrawn JP2022132383A (ja) | 2008-08-15 | 2022-07-12 | 経口投与に好適なｇｃ－ｃ受容体アゴニストポリペプチドの安定な固体製剤 |
| JP2023209257A Withdrawn JP2024015361A (ja) | 2008-08-15 | 2023-12-12 | 経口投与に好適なｇｃ－ｃ受容体アゴニストポリペプチドの安定な固体製剤 |
| JP2025080475A Pending JP2025109853A (ja) | 2008-08-15 | 2025-05-13 | 経口投与に好適なｇｃ－ｃ受容体アゴニストポリペプチドの安定な固体製剤 |
Country Status (32)
| Country | Link |
|---|---|
| US (7) | US8802628B2 (ja) |
| EP (2) | EP3701962A1 (ja) |
| JP (10) | JP5770629B2 (ja) |
| KR (11) | KR20170016522A (ja) |
| CN (5) | CN105168114A (ja) |
| AU (1) | AU2009282446B2 (ja) |
| BR (1) | BRPI0917807A2 (ja) |
| CA (1) | CA2732892C (ja) |
| CL (1) | CL2011000314A1 (ja) |
| CO (1) | CO6351746A2 (ja) |
| CY (1) | CY1122801T1 (ja) |
| DK (1) | DK2328601T3 (ja) |
| EA (1) | EA201170337A1 (ja) |
| ES (1) | ES2785980T3 (ja) |
| GE (1) | GEP20156209B (ja) |
| HK (1) | HK1219062A1 (ja) |
| HR (1) | HRP20200512T2 (ja) |
| HU (1) | HUE049023T2 (ja) |
| IL (1) | IL211028A (ja) |
| LT (1) | LT2328601T (ja) |
| MX (4) | MX390359B (ja) |
| NZ (1) | NZ591713A (ja) |
| PE (2) | PE20110543A1 (ja) |
| PH (1) | PH12015501579B1 (ja) |
| PL (1) | PL2328601T3 (ja) |
| PT (1) | PT2328601T (ja) |
| RS (1) | RS60101B1 (ja) |
| SG (1) | SG193801A1 (ja) |
| SI (1) | SI2328601T1 (ja) |
| SM (1) | SMT202000179T1 (ja) |
| WO (1) | WO2010019266A2 (ja) |
| ZA (1) | ZA201101523B (ja) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20110543A1 (es) | 2008-08-15 | 2011-08-04 | Ironwood Pharmaceuticals Inc | Formulacion solida oral que comprende linaclotida, cation de calcio y leucina |
| US20100221329A1 (en) | 2008-12-03 | 2010-09-02 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase c agonists and methods of use |
| CA2770077A1 (en) * | 2009-08-06 | 2011-02-10 | Ironwood Pharmaceuticals, Inc. | Formulations comprising linaclotide |
| WO2011020054A1 (en) * | 2009-08-13 | 2011-02-17 | Ironwood Pharmaceuticals Inc. | Method for modulating the pharmacodynamic effect of orally administered guanylate cyclase receptor agonists |
| US20130059797A1 (en) * | 2009-11-03 | 2013-03-07 | Forest Laboratories Holdings Limited | Linaclotide for the Treatment of Chronic Constipation |
| WO2011057272A1 (en) | 2009-11-09 | 2011-05-12 | Ironwood Pharmaceuticals, Inc. | Treatments for gastrointestinal disorders |
| JP5984675B2 (ja) | 2009-12-07 | 2016-09-06 | アイアンウッド ファーマシューティカルズ インコーポレイテッド | 胃腸障害の療法 |
| UA108636C2 (xx) | 2010-02-17 | 2015-05-25 | Пептид | |
| EP2603232B1 (en) * | 2010-08-11 | 2019-09-25 | Ironwood Pharmaceuticals, Inc. | Stable formulations of linaclotide |
| CA2811001A1 (en) * | 2010-09-11 | 2012-03-15 | Ironwood Pharmaceuticals, Inc. | Treatment of constipation-predominant irritable bowel syndrome |
| WO2012037380A2 (en) | 2010-09-15 | 2012-03-22 | Synergy Pharmaceuticals Inc. | Formulations of guanylate cyclase c agonists and methods of use |
| US9616097B2 (en) * | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| US9303066B2 (en) | 2011-05-11 | 2016-04-05 | Ironwood Pharmaceuticals, Inc. | Treatments for gastrointestinal disorders |
| CA2835624A1 (en) | 2011-05-11 | 2012-11-15 | Ironwood Pharmaceuticals, Inc. | Treatments for gastrointestinal disorders |
| US9617305B2 (en) | 2011-06-08 | 2017-04-11 | Ironwood Pharmaceuticals, Inc. | Treatments for gastrointestinal disorders |
| US9527887B2 (en) | 2011-06-08 | 2016-12-27 | Ironwood Pharmaceutical, Inc. | Treatments for gastrointestinal disorders |
| MX347354B (es) | 2011-08-17 | 2017-04-24 | Ironwood Pharmaceuticals Inc | Tratamientos para trastornos gastrointestinales. |
| WO2013047795A1 (ja) * | 2011-09-30 | 2013-04-04 | アステラス製薬株式会社 | 粒子状医薬組成物 |
| JP2016521249A (ja) * | 2012-07-12 | 2016-07-21 | フォレスト ラボラトリーズ ホールディングス リミテッド | リナクロチド組成物 |
| US20150361139A1 (en) * | 2013-01-30 | 2015-12-17 | Sandoz Ag | Crystalline form of linaclotide |
| AU2014305843B2 (en) | 2013-08-09 | 2019-08-29 | Ardelyx, Inc. | Compounds and methods for inhibiting phosphate transport |
| UA119335C2 (uk) * | 2013-12-11 | 2019-06-10 | Айронвуд Фармасьютикалз, Інк. | Композиції лінаклотиду з затриманим вивільненням |
| EP3180016A4 (en) * | 2014-08-11 | 2018-01-03 | Sun Pharmaceutical Industries Ltd | Linaclotide stable composition |
| ES2630106T3 (es) * | 2014-10-07 | 2017-08-18 | Cyprumed Gmbh | Formulaciones farmacéuticas para la administración oral de fármacos peptídicos o proteicos |
| CN104569245A (zh) * | 2014-12-08 | 2015-04-29 | 江苏泰洁检测技术有限公司 | 一种工作场所脂肪族胺类中环己胺浓度测定方法 |
| WO2016125064A1 (en) * | 2015-02-02 | 2016-08-11 | Aurobindo Pharma Ltd | Stable compositions comprising linaclotide |
| EP3302440B1 (en) * | 2015-06-05 | 2021-01-06 | Ironwood Pharmaceuticals, Inc. | Modified or targeted release formulations of linaclotide |
| JP2018529749A (ja) | 2015-10-07 | 2018-10-11 | シプルメット・ゲーエムベーハー | ペプチド薬物を経口送達するための医薬製剤 |
| MX2019007574A (es) | 2016-12-21 | 2019-09-04 | Ironwood Pharmaceuticals Inc | Metodos de tratamiento de sindrome de intestino irritable con formulaciones modificadas o de liberacion retardada de linaclotida. |
| CN107669700A (zh) * | 2017-09-14 | 2018-02-09 | 湖南晓林生物科技发展有限公司 | 一种治疗溃疡性结肠炎的药物及其制备方法 |
| WO2020012243A2 (en) | 2018-07-09 | 2020-01-16 | Abbott Laboratories Gmbh | Pharmaceutical composition containing a peptide |
| EP4706758A3 (en) | 2019-05-21 | 2026-05-06 | Ardelyx, Inc. | Methods for inhibiting phosphate transport |
| CN112121021B (zh) * | 2019-06-24 | 2022-03-25 | 深圳翰宇药业股份有限公司 | 一种含利那洛肽的药物组合物及其制备方法 |
| JP2021104941A (ja) * | 2019-12-26 | 2021-07-26 | ニプロ株式会社 | 薬物高含有量錠剤及びその製造方法 |
| CN116056719A (zh) * | 2020-06-30 | 2023-05-02 | 索伦·欧克维克 | 包含鸟苷酸环化酶c(gucy2c)激动剂和短链脂肪酸或其前药的组合的药物组合物 |
| CN113616616A (zh) * | 2021-09-07 | 2021-11-09 | 四川国为制药有限公司 | 一种利那洛肽胶囊制剂及其制备方法 |
| US20230106943A1 (en) * | 2021-09-17 | 2023-04-06 | Peptilogics, Inc. | Engineered antimicrobial peptides and usage thereof |
| CN114632141B (zh) * | 2022-04-19 | 2023-08-01 | 苏州中化药品工业有限公司 | 一种含利那洛肽的药物组合物、胶囊制剂及其制备方法 |
| CN116672309A (zh) * | 2023-07-26 | 2023-09-01 | 北京普诺旺康医药科技有限公司 | 干混悬药物组合物 |
Family Cites Families (71)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH658973A5 (fr) | 1983-12-29 | 1986-12-31 | Nestle Sa | Produit aromatisant. |
| JPS6197229A (ja) * | 1984-10-18 | 1986-05-15 | Chugai Pharmaceut Co Ltd | 安定なエリトロポエチン製剤 |
| DE3729863A1 (de) * | 1987-09-05 | 1989-03-16 | Boehringer Mannheim Gmbh | Stabilisierte erythropoietin-lyophilisate |
| JPS649938A (en) | 1987-06-30 | 1989-01-13 | Agency Ind Science Techn | Oral ingestive composition |
| JPH03505334A (ja) | 1989-04-11 | 1991-11-21 | イミユノバイオロジー・リサーチ・インスチチユート・インコーポレーテツド | 凍結乾燥されたペプチド製剤 |
| IT1240314B (it) | 1989-09-28 | 1993-12-07 | Immunobiology Research Institutes, Inc. | Formulazioni acquose stabilizzate di piccoli peptidi. |
| US5221495A (en) | 1990-04-13 | 1993-06-22 | Colgate-Palmolive Company | Enzyme stabilizing composition and stabilized enzyme containing built detergent compositions |
| US5451410A (en) * | 1993-04-22 | 1995-09-19 | Emisphere Technologies, Inc. | Modified amino acids for encapsulating active agents |
| US6284727B1 (en) | 1993-04-07 | 2001-09-04 | Scios, Inc. | Prolonged delivery of peptides |
| US5681811A (en) | 1993-05-10 | 1997-10-28 | Protein Delivery, Inc. | Conjugation-stabilized therapeutic agent compositions, delivery and diagnostic formulations comprising same, and method of making and using the same |
| US5654278A (en) * | 1994-10-13 | 1997-08-05 | Novo Nordisk A/S | Composition and method comprising growth hormone and leucine |
| IL115592A (en) * | 1994-10-13 | 2000-07-26 | Novo Nordisk As | Stabilized pharmaceutical formulation comprising a growth hormone and leucine |
| US5593696A (en) * | 1994-11-21 | 1997-01-14 | Mcneil-Ppc, Inc. | Stabilized composition of famotidine and sucralfate for treatment of gastrointestinal disorders |
| US5904935A (en) | 1995-06-07 | 1999-05-18 | Alza Corporation | Peptide/protein suspending formulations |
| ZA965368B (en) * | 1995-07-14 | 1997-01-14 | Novo Nordisk As | A pharmaceutical formulation |
| US5916582A (en) | 1996-07-03 | 1999-06-29 | Alza Corporation | Aqueous formulations of peptides |
| AU737664B2 (en) | 1996-07-03 | 2001-08-30 | Alza Corporation | Non-aqueous protic peptide formulations |
| US5932547A (en) | 1996-07-03 | 1999-08-03 | Alza Corporation | Non-aqueous polar aprotic peptide formulations |
| US20020151502A1 (en) * | 1997-10-09 | 2002-10-17 | Albert Sattin | Tri-peptides for neurological and neurobehavior applications |
| US6541606B2 (en) | 1997-12-31 | 2003-04-01 | Altus Biologics Inc. | Stabilized protein crystals formulations containing them and methods of making them |
| US6087478A (en) | 1998-01-23 | 2000-07-11 | The Rockefeller University | Crystal of the N-terminal domain of a STAT protein and methods of use thereof |
| JP2002521322A (ja) | 1998-07-23 | 2002-07-16 | ノボ ノルディスク アクティーゼルスカブ | 安定な医薬製剤の製造のための湿式顆粒化方法 |
| JP2002524358A (ja) * | 1998-09-04 | 2002-08-06 | ガプラスト ゲーエムベーハー | 容 器 |
| MXPA01005346A (es) | 1998-11-27 | 2003-03-27 | Kanji Takada | Una formulacion oral para suministro de farmaco gastrointestinal. |
| US6734162B2 (en) | 2000-01-24 | 2004-05-11 | Minimed Inc. | Mixed buffer system for stabilizing polypeptide formulations |
| JP4711520B2 (ja) * | 2000-03-21 | 2011-06-29 | 日本ケミカルリサーチ株式会社 | 生理活性ペプチド含有粉末 |
| JP2004501191A (ja) | 2000-06-28 | 2004-01-15 | テバ ファーマシューティカル インダストリーズ リミティド | カルベジロール |
| FR2811884B1 (fr) | 2000-07-21 | 2003-01-31 | Oreal | Utilisation en cosmetique de betainates d'amidon et composition les comprenant associes a au moins un agent benefique pour les matieres keratiniques |
| US6613308B2 (en) | 2000-09-19 | 2003-09-02 | Advanced Inhalation Research, Inc. | Pulmonary delivery in treating disorders of the central nervous system |
| AU2001296389A1 (en) | 2000-09-29 | 2002-04-08 | Cognetix, Inc. | Stable peptide formulations |
| EP1351704B1 (en) | 2000-12-21 | 2007-03-07 | Nektar Therapeutics | Storage stable powder compositions of interleukin-4 receptor |
| CA2435835A1 (en) | 2001-02-02 | 2002-08-15 | Pharmacia Corporation | Uroguanylin and cyclooxygenase-2 inhibitor combinations for inhibition of intestinal cancer |
| GB0104371D0 (en) | 2001-02-22 | 2001-04-11 | Clariant Int Ltd | Color improving stabilizing compositions comprising leucine |
| US6573237B2 (en) | 2001-03-16 | 2003-06-03 | Eli Lilly And Company | Protein formulations |
| CA2905585C (en) | 2001-03-29 | 2020-02-18 | Bausch Health Ireland Limited | Guanylate cyclase receptor agonists for the treatment and/or prevention of cancer or polyps |
| AU2002355542A1 (en) | 2001-08-09 | 2003-02-24 | Doctor's Signature Sales And Marketing International Corp. ((Dba)) Life Force International | Protonic formulation |
| US20030104996A1 (en) | 2001-08-30 | 2003-06-05 | Tiansheng Li | L-methionine as a stabilizer for NESP/EPO in HSA-free formulations |
| US20040161776A1 (en) | 2001-10-23 | 2004-08-19 | Maddon Paul J. | PSMA formulations and uses thereof |
| AU2002351755A1 (en) * | 2001-12-21 | 2003-07-15 | Novo Nordisk A/S | Liquid composition of modified factor vii polypeptides |
| JP2003201256A (ja) | 2001-12-28 | 2003-07-18 | Hisamitsu Pharmaceut Co Inc | 大腸送達性経口医薬製剤、大腸癌治療用経口医薬製剤および大腸炎治療用経口医薬製剤 |
| DE10261126A1 (de) * | 2002-08-13 | 2004-03-04 | Aventis Behring Gmbh | Lagerungsstabile, flüssige Fibrinogen-Formulierung |
| PL377479A1 (pl) | 2002-12-11 | 2006-02-06 | Pfizer Products Inc. | Kontrolowane uwalnianie substancji czynnej do środowiska o wysokiej zawartości tłuszczu |
| EP1911763B1 (en) | 2003-01-28 | 2010-08-11 | Ironwood Pharmaceuticals, Inc. | Compositions for the treatment of gastrointestinal disorders |
| US7371727B2 (en) | 2003-01-28 | 2008-05-13 | Microbia, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| US7304036B2 (en) | 2003-01-28 | 2007-12-04 | Microbia, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| ATE390142T1 (de) | 2003-05-14 | 2008-04-15 | Indus Biotech Pvt Ltd | Synergistische zusammensetzung zur behandlung von diabetes mellitus |
| EP1641486B1 (en) * | 2003-06-10 | 2012-04-18 | LG Life Sciences Ltd. | Stable, aqueous solution of human erythropoietin, not containing serum albumin |
| JP2007501866A (ja) | 2003-06-13 | 2007-02-01 | マイクロバイア インコーポレイテッド | 胃腸疾患の治療のための方法および組成物 |
| US7494979B2 (en) | 2003-06-13 | 2009-02-24 | Ironwood Pharmaceuticals, Inc. | Method for treating congestive heart failure and other disorders |
| KR100560697B1 (ko) | 2003-08-06 | 2006-03-16 | 씨제이 주식회사 | 알부민을 함유하지 않는 에리스로포이에틴 제제 |
| DE202004020676U1 (de) | 2004-03-10 | 2005-11-10 | Bioceuticals Arzneimittel Ag | Erythropoietin-Flüssigformulierung |
| WO2006071102A1 (en) | 2004-12-30 | 2006-07-06 | Dobeel Co., Ltd. | Spray-dried composition containing collectin family proteins or variants therof and process for preparing the same |
| WO2007022531A2 (en) | 2005-08-19 | 2007-02-22 | Microbia, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| WO2007044375A2 (en) | 2005-10-06 | 2007-04-19 | Nastech Pharmaceutical Company Inc. | Pth formulations and methods of use |
| EP1991241A4 (en) * | 2006-02-23 | 2009-07-08 | Iomedix Sleep Internat Srl | COMPOSITIONS AND METHODS FOR INTRODUCING AND MAINTAINING HIGH-QUALITY SLEEPING |
| WO2007101161A2 (en) * | 2006-02-24 | 2007-09-07 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| ITMI20060629A1 (it) | 2006-03-31 | 2007-10-01 | Daniele Giovannone | Composizioni solide orali a base di s-adenosilmetionina e processo per il loro ottenimento |
| AU2007272272B2 (en) | 2006-07-10 | 2012-04-12 | Pba3 Biomed Gmbh | Antimicrobial peptides |
| EP2359808B1 (en) | 2006-08-09 | 2013-05-22 | Intarcia Therapeutics, Inc | Osmotic delivery systems and piston assemblies |
| BRPI0716261A2 (pt) | 2006-08-31 | 2013-08-06 | Novartis Ag | composiÇÕes farmacÊuticas compreendendo hch para distribuiÇço oral |
| JP2010513462A (ja) * | 2006-12-20 | 2010-04-30 | バイエル・ヘルスケア・エルエルシー | 第ＶＩＩおよび第ＶＩＩａ因子組成物 |
| WO2008106429A2 (en) | 2007-02-26 | 2008-09-04 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of heart failure and other disorders |
| MX354786B (es) | 2007-06-04 | 2018-03-21 | Synergy Pharmaceuticals Inc | Agonistas de guanilato ciclasa utiles para el tratamiento de trastornos gastrointestinales, inflamacion, cancer y otros trastornos. |
| PE20110543A1 (es) | 2008-08-15 | 2011-08-04 | Ironwood Pharmaceuticals Inc | Formulacion solida oral que comprende linaclotida, cation de calcio y leucina |
| EP2331077A2 (en) | 2008-09-04 | 2011-06-15 | Ironwood Pharmaceuticals, Inc. | Stable forlulation comprising therapeutic polypeptides for oral administration |
| WO2010027405A2 (en) * | 2008-09-04 | 2010-03-11 | Ironwood Pharmaceuticals, Inc. | Stable solid formulations of gc-c receptor agonist polypeptides suitable for oral administration |
| US20100221329A1 (en) | 2008-12-03 | 2010-09-02 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase c agonists and methods of use |
| US20130012454A1 (en) * | 2009-07-06 | 2013-01-10 | Ironwood Pharmaceuticals, Inc. | Orally Disintegrating Compositions of Linaclotide |
| CA2770077A1 (en) | 2009-08-06 | 2011-02-10 | Ironwood Pharmaceuticals, Inc. | Formulations comprising linaclotide |
| MX2012001691A (es) * | 2009-08-12 | 2012-02-29 | Forest Lab Holdings Ltd | Composiciones de linaclotida que se desintegran oralmente. |
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