JPH01500270A - ５‐ヘテロ‐またはアリール‐置換された‐イミダゾ［２，１‐ａ］イソキノリン類 - Google Patents

５‐ヘテロ‐またはアリール‐置換された‐イミダゾ［２，１‐ａ］イソキノリン類

Info

Publication number: JPH01500270A
Authority: JP; Japan
Prior art keywords: tables; formula; phenyl; formulas; alkyl
Prior art date: 1986-07-14
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

JP62504237A

Other languages

English (en)

Japanese (ja)

Other versions

JPH0588713B2 (de

Inventor

ハウリハン，ウイリアム・ジヨセフ

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Sandoz AG

Original Assignee

Sandoz AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-07-14

Filing date

1987-07-07

Publication date

1989-02-02

1987-07-07 Application filed by Sandoz AG filed Critical Sandoz AG

1989-02-02 Publication of JPH01500270A publication Critical patent/JPH01500270A/ja

1993-12-24 Publication of JPH0588713B2 publication Critical patent/JPH0588713B2/ja

Status Granted legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
- C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Diabetes (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Hematology (AREA)
Pulmonology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)

JP62504237A 1986-07-14 1987-07-07 ５‐ヘテロ‐またはアリール‐置換された‐イミダゾ［２，１‐ａ］イソキノリン類 Granted JPH01500270A (ja)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date
US88511586A	1986-07-14	1986-07-14
US885,115		1986-07-14
US1351587A	1987-02-11	1987-02-11
US013,515		1993-02-04

Publications (2)

Publication Number	Publication Date
JPH01500270A true JPH01500270A (ja)	1989-02-02
JPH0588713B2 JPH0588713B2 (de)	1993-12-24

Family

ID=26684931

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP62504237A Granted JPH01500270A (ja)	1986-07-14	1987-07-07	５‐ヘテロ‐またはアリール‐置換された‐イミダゾ［２，１‐ａ］イソキノリン類

Country Status (22)

Country	Link
EP (1)	EP0258175B1 (de)
JP (1)	JPH01500270A (de)
KR (1)	KR960003609B1 (de)
AT (1)	ATE74357T1 (de)
AU (1)	AU604739B2 (de)
CA (1)	CA1317942C (de)
CY (1)	CY1828A (de)
DE (1)	DE3777919D1 (de)
DK (1)	DK170213B1 (de)
ES (1)	ES2032861T3 (de)
FI (1)	FI88159C (de)
GR (1)	GR3004258T3 (de)
HK (1)	HK71295A (de)
HU (1)	HU206114B (de)
IE (1)	IE60277B1 (de)
IL (1)	IL83164A (de)
MY (1)	MY101895A (de)
NZ (1)	NZ221054A (de)
PH (1)	PH24430A (de)
PL (1)	PL154159B1 (de)
SG (1)	SG8595G (de)
WO (1)	WO1988000587A2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4910206A (en) *	1986-07-14	1990-03-20	Sandoz Pharmaceuticals Corp.	5-hetero-or aryl-substituted-imidazo(2,1-a)isoquinolines and their use as PAF receptor antagonists
EP0338993A1 (de) *	1988-04-21	1989-10-25	Sandoz Ag	6-Aryl-substituierte 4H-Thieno [2,3-e][1,2,4] triazole [3,4-c] [1,4] diazepine
ATE118777T1 (de) *	1988-05-05	1995-03-15	Sandoz Ag	5-aryl-substituierte-2,3-dihydro-imidazo(1,2- a>furo(3,2-c>- oder thieno(2,3-c>pyridine.
US5939090A (en)	1996-12-03	1999-08-17	3M Innovative Properties Company	Gel formulations for topical drug delivery
CN1076728C (zh) *	1999-02-05	2001-12-26	浙江大学	2－芳基咪唑并[2,1－a]异喹啉的衍生物及其用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1347493A (en) *	1971-02-11	1974-02-27	Aspro Nicholas Ltd	Benzazine derivatives

1987
- 1987-07-07 EP EP87810387A patent/EP0258175B1/de not_active Expired - Lifetime
- 1987-07-07 DE DE8787810387T patent/DE3777919D1/de not_active Expired - Lifetime
- 1987-07-07 HU HU873833A patent/HU206114B/hu not_active IP Right Cessation
- 1987-07-07 AU AU76941/87A patent/AU604739B2/en not_active Ceased
- 1987-07-07 AT AT87810387T patent/ATE74357T1/de not_active IP Right Cessation
- 1987-07-07 JP JP62504237A patent/JPH01500270A/ja active Granted
- 1987-07-07 WO PCT/EP1987/000366 patent/WO1988000587A2/en not_active Ceased
- 1987-07-07 ES ES198787810387T patent/ES2032861T3/es not_active Expired - Lifetime
- 1987-07-11 MY MYPI87000989A patent/MY101895A/en unknown
- 1987-07-13 CA CA000542087A patent/CA1317942C/en not_active Expired - Fee Related
- 1987-07-13 IL IL83164A patent/IL83164A/xx unknown
- 1987-07-13 PL PL1987266801A patent/PL154159B1/pl unknown
- 1987-07-13 NZ NZ221054A patent/NZ221054A/xx unknown
- 1987-07-13 IE IE187687A patent/IE60277B1/en not_active IP Right Cessation
- 1987-07-14 PH PH35535A patent/PH24430A/en unknown
1988
- 1988-03-11 FI FI881165A patent/FI88159C/fi not_active IP Right Cessation
- 1988-03-11 KR KR88700272A patent/KR960003609B1/ko not_active Expired - Fee Related
- 1988-03-14 DK DK138388A patent/DK170213B1/da not_active IP Right Cessation
1992
- 1992-04-02 GR GR920400538T patent/GR3004258T3/el unknown
1995
- 1995-01-18 SG SG8595A patent/SG8595G/en unknown
- 1995-05-11 HK HK71295A patent/HK71295A/en not_active IP Right Cessation
- 1995-12-01 CY CY182895A patent/CY1828A/xx unknown

Also Published As

Publication number	Publication date
PH24430A (en)	1990-06-25
EP0258175B1 (de)	1992-04-01
KR880701718A (ko)	1988-11-04
CA1317942C (en)	1993-05-18
NZ221054A (en)	1990-10-26
FI881165A7 (fi)	1988-03-11
GR3004258T3 (de)	1993-03-31
AU604739B2 (en)	1991-01-03
IL83164A (en)	1991-05-12
AU7694187A (en)	1988-02-10
FI881165A0 (fi)	1988-03-11
HK71295A (en)	1995-05-19
WO1988000587A3 (en)	1988-04-07
SG8595G (en)	1995-06-16
DK138388A (da)	1988-03-14
FI88159C (fi)	1993-04-13
ATE74357T1 (de)	1992-04-15
CY1828A (en)	1995-12-01
WO1988000587A2 (en)	1988-01-28
HUT46005A (en)	1988-09-28
PL154159B1 (en)	1991-07-31
EP0258175A3 (en)	1988-05-04
KR960003609B1 (en)	1996-03-20
DK138388D0 (da)	1988-03-14
PL266801A1 (en)	1988-09-29
IE60277B1 (en)	1994-06-29
DK170213B1 (da)	1995-06-19
MY101895A (en)	1992-02-15
ES2032861T3 (es)	1993-03-01
EP0258175A2 (de)	1988-03-02
DE3777919D1 (de)	1992-05-07
IE871876L (en)	1988-01-14
JPH0588713B2 (de)	1993-12-24
IL83164A0 (en)	1987-12-31
HU206114B (en)	1992-08-28
FI88159B (fi)	1992-12-31

Similar Documents

Publication	Publication Date	Title
EP0142801B1 (de)	1989-05-31	Als PAF-Antagonisten verwendbare Inden-Derivate
SU1442068A3 (ru)	1988-11-30	Способ получени производных хинона
JP2007502845A (ja)	2007-02-15	がんまたはウイルス疾患を治療するための三環性複素環化合物、組成物および方法
JP2978850B2 (ja)	1999-11-15	２−アミノベンズアゼピン誘導体
CA2054091A1 (en)	1992-04-25	Isoquinolinone derivatives
WO2012070015A1 (en)	2012-05-31	Inhibitors of the activity of complex iii of the mitochondrial electron transport chain and use thereof for treating diseases
JPS6267081A (ja)	1987-03-26	Ｐａｆきつ抗剤としての新規な２，５−ジアリ−ルテトラヒドロチオフエン類及びその類縁体
US20070293527A9 (en)	2007-12-20	Polycyclic compounds as potent alpha2-adrenoceptor antagonists
JPS6028979A (ja)	1985-02-14	イミダゾキナゾリン類化合物
EP0365089A2 (de)	1990-04-25	2-Aryl-5(3-methoxy-5-(hydroxypropylsulfonyl)-4-propoxyphenyl)tetrahydrothiophen und Analoge
US4910206A (en)	1990-03-20	5-hetero-or aryl-substituted-imidazo(2,1-a)isoquinolines and their use as PAF receptor antagonists
CA1266271A (en)	1990-02-27	2,5-diaryl tetrahydrothiophenes and analogs thereof as paf-antagonists
RU2001911C1 (ru)	1993-10-30	Способ получени замещенных 1,2,3,4-тетрагидронафталинов или их фармацевтически приемлемых аддитивных солей кислоты
DK175801B1 (da)	2005-02-28	Anvendelse af substituerede alkylidendithio-bis-(substituerede)-phenoler til fremstilling af et lægemiddel til inhibering af interleukin-1-medierede virkninger bortset fra atherosklerose og/eller hyperlipidæmi
US4992428A (en)	1991-02-12	5-aryl-substituted-2,3-dihydro-imidazo[1,2-a]furo- and thieno pyridines
EP0258175B1 (de)	1992-04-01	5-Hetero- oder -Aryl-substituierte Imidazo[2,1-a]isochinoline
JPH06507377A (ja)	1994-08-25	薬剤組成物
JPS60218377A (ja)	1985-11-01	４−フエニルフタラジン誘導体及びそれを有効成分とする循環改善剤
EP0194665A1 (de)	1986-09-17	Alkylaminoalkylpyridinmethanolderivate als beta-adrenerge Rezeptor-Agonisten
JPH0631228B2 (ja)	1994-04-27	新規な５―（ω―アンモニオアシルオキシメチレン）テトラヒドロフラン類及びテトラヒドロチオフェン類、それらの製造法並びにそれらを含有する抗ＰＡＦ剤
FI85481B (fi)	1992-01-15	Foerfarande foer framstaellning av 2,3 -dihydro-1-(8-metyl-1,2,4-triazolo/4,3-b/pyridazin-6-yl)-4(1h) -pyridinon.
WO1988006157A1 (en)	1988-08-25	5-HETERO- OR ARYL-SUBSTITUTED-IMIDAZO[2,1-a]ISOQUINOLINES
JPS63101322A (ja)	1988-05-06	トロンボキサンａ↓２受容体拮抗剤
JPH11310530A (ja)	1999-11-09	一酸化窒素産生抑制剤
JPH0615540B2 (ja)	1994-03-02	新規なグリセロールアセタールのアミノアシレート類、それらの製造方法及びそれらを含む医薬組成物