JPH08502082A - 生体適合性ポリマー結合体 - Google Patents
生体適合性ポリマー結合体Info
- Publication number
- JPH08502082A JPH08502082A JP6503427A JP50342794A JPH08502082A JP H08502082 A JPH08502082 A JP H08502082A JP 6503427 A JP6503427 A JP 6503427A JP 50342794 A JP50342794 A JP 50342794A JP H08502082 A JPH08502082 A JP H08502082A
- Authority
- JP
- Japan
- Prior art keywords
- collagen
- peg
- conjugate
- polymer
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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- OFMQLVRLOGHAJI-FGHAYEPSSA-N (4r,7s,10s,13r,16s,19r)-n-[(2s,3r)-1-amino-3-hydroxy-1-oxobutan-2-yl]-19-[[(2r)-2-amino-3-phenylpropanoyl]amino]-10-[3-(diaminomethylideneamino)propyl]-7-[(1r)-1-hydroxyethyl]-16-[(4-hydroxyphenyl)methyl]-13-(1h-indol-3-ylmethyl)-3,3-dimethyl-6,9,12,15,18 Chemical compound C([C@H]1C(=O)N[C@H](CC=2C3=CC=CC=C3NC=2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](C(=O)N[C@@H](C(SSC[C@@H](C(=O)N1)NC(=O)[C@H](N)CC=1C=CC=CC=1)(C)C)C(=O)N[C@@H]([C@H](O)C)C(N)=O)[C@@H](C)O)C1=CC=C(O)C=C1 OFMQLVRLOGHAJI-FGHAYEPSSA-N 0.000 claims description 3
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- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0069—Chondroitin-4-sulfate, i.e. chondroitin sulfate A; Dermatan sulfate, i.e. chondroitin sulfate B or beta-heparin; Chondroitin-6-sulfate, i.e. chondroitin sulfate C; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08H—DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
- C08H1/00—Macromolecular products derived from proteins
- C08H1/06—Macromolecular products derived from proteins derived from horn, hoofs, hair, skin or leather
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
- C09J189/00—Adhesives based on proteins; Adhesives based on derivatives thereof
- C09J189/04—Products derived from waste materials, e.g. horn, hoof or hair
- C09J189/06—Products derived from waste materials, e.g. horn, hoof or hair derived from leather or skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2/07—Stent-grafts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00365—Proteins; Polypeptides; Degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/23—Carbohydrates
- A61L2300/236—Glycosaminoglycans, e.g. heparin, hyaluronic acid, chondroitin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
- A61L2300/414—Growth factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/426—Immunomodulating agents, i.e. cytokines, interleukins, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/16—Materials or treatment for tissue regeneration for reconstruction of eye parts, e.g. intraocular lens, cornea
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2666/00—Composition of polymers characterized by a further compound in the blend, being organic macromolecular compounds, natural resins, waxes or and bituminous materials, non-macromolecular organic substances, inorganic substances or characterized by their function in the composition
- C08L2666/02—Organic macromolecular compounds, natural resins, waxes or and bituminous materials
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Molecular Biology (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Polymers & Plastics (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Composite Materials (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Polyethers (AREA)
- Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
Applications Claiming Priority (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/907,518 US5324775A (en) | 1988-11-21 | 1992-07-02 | Biologically inert, biocompatible-polymer conjugates |
| US07/907,518 | 1992-07-02 | ||
| US07/922,541 | 1992-07-30 | ||
| US07/922,541 US5328955A (en) | 1988-11-21 | 1992-07-30 | Collagen-polymer conjugates |
| US98493392A | 1992-12-02 | 1992-12-02 | |
| US07/984,197 US5308889A (en) | 1988-11-21 | 1992-12-02 | Dehydrated collagen-polymer strings |
| US07/984,933 | 1992-12-02 | ||
| US07/984,197 | 1992-12-02 | ||
| US07/985,680 | 1992-12-02 | ||
| US07/985,680 US5292802A (en) | 1988-11-21 | 1992-12-02 | Collagen-polymer tubes for use in vascular surgery |
| US2503293A | 1993-03-02 | 1993-03-02 | |
| US08/025,032 | 1993-03-02 | ||
| PCT/US1993/006292 WO1994001483A1 (fr) | 1992-07-02 | 1993-07-01 | Conjugues polymeres biocompatibles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH08502082A true JPH08502082A (ja) | 1996-03-05 |
Family
ID=27556046
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP6503427A Pending JPH08502082A (ja) | 1992-07-02 | 1993-07-01 | 生体適合性ポリマー結合体 |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP0648239A4 (fr) |
| JP (1) | JPH08502082A (fr) |
| AU (1) | AU677789B2 (fr) |
| WO (1) | WO1994001483A1 (fr) |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004173941A (ja) * | 2002-11-27 | 2004-06-24 | Olympus Corp | カルシウム傾斜材料とその製造方法 |
| JP2004359895A (ja) * | 2003-06-06 | 2004-12-24 | Mcrotech Kk | 医療用組成物 |
| JP2005272398A (ja) * | 2004-03-25 | 2005-10-06 | Shiseido Co Ltd | 皮膚のシワを改善する方法及びシワ改善具 |
| JP2007023280A (ja) * | 2005-07-12 | 2007-02-01 | Kwangju Inst Of Science & Technol | シクロデキストリンとポリ(オキシエチレン)の結合体、及びその製造方法 |
| WO2007083522A1 (fr) * | 2006-01-18 | 2007-07-26 | Next21 K. K. | Composition formant gel a usage medical, dispositifs d'application de la composition et vehicule reglant la liberation de medicament |
| WO2010070775A1 (fr) * | 2008-12-19 | 2010-06-24 | 株式会社ネクスト21 | Hydrogel injectable à ultra-haute résistance et procédé de fabrication associé |
| JP2010528046A (ja) * | 2007-05-23 | 2010-08-19 | アラーガン、インコーポレイテッド | 架橋コラーゲンおよびその使用 |
| WO2013021836A1 (fr) * | 2011-08-05 | 2013-02-14 | 公立大学法人大阪市立大学 | Hydrogel fonctionnel |
| JP2015061606A (ja) * | 2006-03-29 | 2015-04-02 | インセプト エルエルシー | 医療用高吸収性凍結乾燥ヒドロゲル |
| JPWO2021025005A1 (fr) * | 2019-08-05 | 2021-02-11 |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5565519A (en) * | 1988-11-21 | 1996-10-15 | Collagen Corporation | Clear, chemically modified collagen-synthetic polymer conjugates for ophthalmic applications |
| US5643464A (en) * | 1988-11-21 | 1997-07-01 | Collagen Corporation | Process for preparing a sterile, dry crosslinking agent |
| US5936035A (en) * | 1988-11-21 | 1999-08-10 | Cohesion Technologies, Inc. | Biocompatible adhesive compositions |
| US5475052A (en) * | 1988-11-21 | 1995-12-12 | Collagen Corporation | Collagen-synthetic polymer matrices prepared using a multiple step reaction |
| US5510418A (en) * | 1988-11-21 | 1996-04-23 | Collagen Corporation | Glycosaminoglycan-synthetic polymer conjugates |
| SK281042B6 (sk) | 1992-09-18 | 2000-11-07 | Yamanouchi Pharmaceutical Co., Ltd | Prípravok hydrogélového typu s ustáleným uvoľňovaním |
| US5548064A (en) * | 1993-05-24 | 1996-08-20 | Biotech Australia Pty Limited | Vitamin B12 conjugates with EPO, analogues thereof and pharmaceutical compositions |
| CA2140053C (fr) * | 1994-02-09 | 2000-04-04 | Joel S. Rosenblatt | Systeme a base de collagene pour l'administration de drogue injectable, et utilisation |
| AU1014695A (en) * | 1994-02-17 | 1995-08-24 | Collagen Corporation | Collagen-synthetic polymer conjugates having controlled fiber size distributions |
| JPH10501706A (ja) * | 1994-04-04 | 1998-02-17 | コラーゲン コーポレイション | 細胞−ゲル |
| CA2151547C (fr) * | 1994-06-10 | 2010-10-12 | Elliott A. Gruskin | Proteines chimeriques recombinantes et modes d'utilisation de ces proteines |
| EP0713707A1 (fr) | 1994-11-23 | 1996-05-29 | Collagen Corporation | Composition de collagène insectable, réticulable in situ pour augmenter des tissus |
| US6962979B1 (en) | 1995-03-14 | 2005-11-08 | Cohesion Technologies, Inc. | Crosslinkable biomaterial compositions containing hydrophobic and hydrophilic crosslinking agents |
| CA2165728A1 (fr) * | 1995-03-14 | 1996-09-15 | Woonza M. Rhee | Utilisation d'agents de reticulation hydrophobes pour preparer des compositions de biomatiere reticulee |
| DE19514087A1 (de) * | 1995-04-13 | 1996-10-17 | Deutsches Krebsforsch | Konjugat aus einem Wirkstoff, einem Polyether und ggfs. einem nicht als körperfremd angesehenen, nativen Protein |
| PT831882E (pt) * | 1995-06-07 | 2005-01-31 | Organogenesis Inc | Composicoes de segmentos de fibra de colagenio reconstituido e metodos de preparacao das mesmas |
| US5776193A (en) | 1995-10-16 | 1998-07-07 | Orquest, Inc. | Bone grafting matrix |
| JPH09143093A (ja) | 1995-11-17 | 1997-06-03 | Hoechst Japan Ltd | 軟骨・骨誘導性修復用材料 |
| US5752974A (en) * | 1995-12-18 | 1998-05-19 | Collagen Corporation | Injectable or implantable biomaterials for filling or blocking lumens and voids of the body |
| WO1997022371A1 (fr) | 1995-12-18 | 1997-06-26 | Collagen Corporation | Composition a base de polymeres reticules et leur procede d'utilisation |
| JP2002504083A (ja) * | 1996-03-05 | 2002-02-05 | オーケスト インコーポレイテッド | ヒアルロン酸および増殖因子による骨の増殖を促進する方法 |
| US5855615A (en) * | 1996-06-07 | 1999-01-05 | Menlo Care, Inc. | Controller expansion sphincter augmentation media |
| TW555765B (en) | 1996-07-09 | 2003-10-01 | Amgen Inc | Low molecular weight soluble tumor necrosis factor type-I and type-II proteins |
| US6083522A (en) * | 1997-01-09 | 2000-07-04 | Neucoll, Inc. | Devices for tissue repair and methods for preparation and use thereof |
| GB9722604D0 (en) * | 1997-10-28 | 1997-12-24 | Cancer Res Campaign Tech | Heparin-binding growth factor derivatives |
| US6660843B1 (en) | 1998-10-23 | 2003-12-09 | Amgen Inc. | Modified peptides as therapeutic agents |
| EP1316323A1 (fr) * | 1998-12-31 | 2003-06-04 | Angiotech Pharmaceuticals, Inc. | Prothèses endovasculaires à revêtements bioactifs |
| IL143922A0 (en) * | 1998-12-31 | 2002-04-21 | Angiotech Pharm Inc | A stent graft with a bioactive coating |
| FR2790475B1 (fr) | 1999-03-02 | 2003-01-24 | Flamel Tech Sa | Peptides collageniques modifies par greffage de fonctions mercapto, l'un de leurs procedes d'obtention et leurs applications comme biomateriaux |
| WO2001005434A2 (fr) * | 1999-07-20 | 2001-01-25 | Amgen Inc. | Conjugues hyaluroniques acide-proteine, compositions pharmaceutiques et procedes correspondants |
| US6592794B1 (en) | 1999-09-28 | 2003-07-15 | Organogenesis Inc. | Process of making bioengineered collagen fibrils |
| AU6459299A (en) * | 1999-10-29 | 2001-05-14 | Min Hu | Surface treatment with polypeptides to improve fibroblast adhesion to hyaluronan |
| EP1242008B1 (fr) | 1999-12-17 | 2006-03-08 | Cartificial A/S | Dispositif prothetique |
| SG98393A1 (en) | 2000-05-19 | 2003-09-19 | Inst Materials Research & Eng | Injectable drug delivery systems with cyclodextrin-polymer based hydrogels |
| EP1311657A2 (fr) * | 2000-08-21 | 2003-05-21 | Rice University | Production de proteine matricielle d'amelioration de charpentes pour genie tissulaire |
| AU2002233097A1 (en) * | 2002-02-28 | 2003-09-09 | Eidgenossische Technische Hochschule Zurich Oberflachentechnik | Biomedical implant surfaces with osteogenic properties |
| DE10209821A1 (de) | 2002-03-06 | 2003-09-25 | Biotechnologie Ges Mittelhesse | Kopplung von Proteinen an ein modifiziertes Polysaccharid |
| US7538092B2 (en) | 2002-10-08 | 2009-05-26 | Fresenius Kabi Deutschland Gmbh | Pharmaceutically active oligosaccharide conjugates |
| AU2003303513A1 (en) * | 2002-12-30 | 2004-07-29 | Angiotech International Ag | Tissue reactive compounds and compositions and uses thereof |
| AU2003300076C1 (en) | 2002-12-30 | 2010-03-04 | Angiotech International Ag | Drug delivery from rapid gelling polymer composition |
| FR2850282B1 (fr) | 2003-01-27 | 2007-04-06 | Jerome Asius | Implant injectable a base de ceramique pour le comblement de rides, depressions cutanees et cicatrices, et sa preparation |
| DE10303584A1 (de) * | 2003-01-30 | 2004-08-12 | Stauss, Robert, Dr. | Verwendung von Erythropoietin (EPO) als ein Beschichtungsmaterial auf medizinischen Implantaten |
| WO2005014655A2 (fr) | 2003-08-08 | 2005-02-17 | Fresenius Kabi Deutschland Gmbh | Conjugues d'amidon d'hydroxyalkyle et de proteine |
| US8002830B2 (en) | 2004-02-06 | 2011-08-23 | Georgia Tech Research Corporation | Surface directed cellular attachment |
| AU2005212339B2 (en) | 2004-02-06 | 2010-11-25 | Georgia Tech Research Corporation | Load bearing biocompatible device |
| EP1796602A4 (fr) | 2004-09-17 | 2016-10-19 | Angiotech Pharm Inc | Composes multifonctionels pour la formation de biomateriaux reticules et leurs procedes de preparation et d'utilisation |
| MX2010002448A (es) | 2007-08-27 | 2010-10-04 | Biogenerix Ag | Formulacion liquida del g-csf conjugado. |
| EP2757964B1 (fr) | 2011-05-26 | 2016-05-04 | Cartiva, Inc. | Implant d'articulation conique et outils associés |
| WO2016161026A1 (fr) | 2015-03-31 | 2016-10-06 | Cartiva, Inc. | Implants carpométacarpiens (cmc) et procédés |
| US9907663B2 (en) | 2015-03-31 | 2018-03-06 | Cartiva, Inc. | Hydrogel implants with porous materials and methods |
| WO2016168363A1 (fr) | 2015-04-14 | 2016-10-20 | Cartiva, Inc. | Outillage pour création d'une ouverture conique dans le tissu et procédés associés |
| US20160303281A1 (en) * | 2015-04-17 | 2016-10-20 | Rochal Industries, Llc | Composition and kits for pseudoplastic microgel matrices |
| WO2020226250A1 (fr) * | 2019-05-08 | 2020-11-12 | 서울대학교병원 | Implant médical modifié en surface avec un polypeptide fonctionnel |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US3091542A (en) * | 1960-09-20 | 1963-05-28 | Dow Chemical Co | Insolubilization of water-soluble cellulose ethers |
| US3949073A (en) * | 1974-11-18 | 1976-04-06 | The Board Of Trustees Of Leland Stanford Junior University | Process for augmenting connective mammalian tissue with in situ polymerizable native collagen solution |
| JPS5896026A (ja) * | 1981-10-30 | 1983-06-07 | Nippon Chemiphar Co Ltd | 新規ウロキナ−ゼ誘導体およびその製造法ならびにそれを含有する血栓溶解剤 |
| US4424208A (en) * | 1982-01-11 | 1984-01-03 | Collagen Corporation | Collagen implant material and method for augmenting soft tissue |
| US4487865A (en) * | 1983-12-15 | 1984-12-11 | Biomatrix, Inc. | Polymeric articles modified with hyaluronate |
| US4496689A (en) * | 1983-12-27 | 1985-01-29 | Miles Laboratories, Inc. | Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer |
| JPS643116A (en) * | 1987-06-25 | 1989-01-06 | Nippon Oil & Fats Co Ltd | Plaster for patch |
| US4847325A (en) * | 1988-01-20 | 1989-07-11 | Cetus Corporation | Conjugation of polymer to colony stimulating factor-1 |
| US5162430A (en) * | 1988-11-21 | 1992-11-10 | Collagen Corporation | Collagen-polymer conjugates |
| JPH06501008A (ja) * | 1990-08-30 | 1994-01-27 | ザ バイオメンブレン インスティテュート | オリゴ糖あるいはオリゴ糖抗原または抗体による転移能および侵襲性の抑制 |
-
1993
- 1993-07-01 AU AU46620/93A patent/AU677789B2/en not_active Ceased
- 1993-07-01 WO PCT/US1993/006292 patent/WO1994001483A1/fr not_active Ceased
- 1993-07-01 EP EP93916926A patent/EP0648239A4/fr not_active Withdrawn
- 1993-07-01 JP JP6503427A patent/JPH08502082A/ja active Pending
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004173941A (ja) * | 2002-11-27 | 2004-06-24 | Olympus Corp | カルシウム傾斜材料とその製造方法 |
| JP2004359895A (ja) * | 2003-06-06 | 2004-12-24 | Mcrotech Kk | 医療用組成物 |
| JP2005272398A (ja) * | 2004-03-25 | 2005-10-06 | Shiseido Co Ltd | 皮膚のシワを改善する方法及びシワ改善具 |
| JP2007023280A (ja) * | 2005-07-12 | 2007-02-01 | Kwangju Inst Of Science & Technol | シクロデキストリンとポリ(オキシエチレン)の結合体、及びその製造方法 |
| WO2007083522A1 (fr) * | 2006-01-18 | 2007-07-26 | Next21 K. K. | Composition formant gel a usage medical, dispositifs d'application de la composition et vehicule reglant la liberation de medicament |
| JPWO2007083522A1 (ja) * | 2006-01-18 | 2009-06-11 | 株式会社ネクスト21 | 医療用ゲル形成組成物,その組成物の投与デバイス及び薬剤放出制御担体 |
| JP2015061606A (ja) * | 2006-03-29 | 2015-04-02 | インセプト エルエルシー | 医療用高吸収性凍結乾燥ヒドロゲル |
| JP2010528046A (ja) * | 2007-05-23 | 2010-08-19 | アラーガン、インコーポレイテッド | 架橋コラーゲンおよびその使用 |
| WO2010070775A1 (fr) * | 2008-12-19 | 2010-06-24 | 株式会社ネクスト21 | Hydrogel injectable à ultra-haute résistance et procédé de fabrication associé |
| JPWO2010070775A1 (ja) * | 2008-12-19 | 2012-05-24 | 株式会社ネクスト21 | 超高強度インジェクタブルハイドロゲル及びその製造方法 |
| WO2013021836A1 (fr) * | 2011-08-05 | 2013-02-14 | 公立大学法人大阪市立大学 | Hydrogel fonctionnel |
| JPWO2013021836A1 (ja) * | 2011-08-05 | 2015-03-05 | 公立大学法人大阪市立大学 | 機能性ハイドロゲル |
| JPWO2021025005A1 (fr) * | 2019-08-05 | 2021-02-11 |
Also Published As
| Publication number | Publication date |
|---|---|
| AU4662093A (en) | 1994-01-31 |
| AU677789B2 (en) | 1997-05-08 |
| EP0648239A1 (fr) | 1995-04-19 |
| EP0648239A4 (fr) | 1995-09-27 |
| WO1994001483A1 (fr) | 1994-01-20 |
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