JPH10506410A - 抗腫瘍剤及び抗ウイルス剤としてのビス−（２−ハロエチル）アミノフェニル置換ジスタマイシン誘導体 - Google Patents

抗腫瘍剤及び抗ウイルス剤としてのビス−（２−ハロエチル）アミノフェニル置換ジスタマイシン誘導体

Info

Publication number: JPH10506410A
Authority: JP; Japan
Prior art keywords: carboxamide; methyl; pyrrole; compound; formula
Prior art date: 1995-07-21
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

JP9506209A

Other languages

English (en)

Japanese (ja)

Inventor

コツツイ，パオロ

ベリア，イターロ

カポロンゴ，ラウラ

フランツエツテイ，クリステイーナ

Original Assignee

フアルマシア・エ・アツプジヨン・エツセ・ピー・アー

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-07-21

Filing date

1996-06-19

Publication date

1998-06-23

1996-06-19 Application filed by フアルマシア・エ・アツプジヨン・エツセ・ピー・アー filed Critical フアルマシア・エ・アツプジヨン・エツセ・ピー・アー

1998-06-23 Publication of JPH10506410A publication Critical patent/JPH10506410A/ja

Status Pending legal-status Critical Current

Links

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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Virology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pyrrole Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

JP9506209A 1995-07-21 1996-06-19 抗腫瘍剤及び抗ウイルス剤としてのビス−（２−ハロエチル）アミノフェニル置換ジスタマイシン誘導体 Pending JPH10506410A (ja)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GBGB9514993.6A GB9514993D0 (en)	1995-07-21	1995-07-21	Site specific phenyl nitrogen mustards
GB9514993.6		1995-07-21
PCT/EP1996/002659 WO1997003957A1 (fr)	1995-07-21	1996-06-19	Derives de la distamycine a substitution bis-(2-haloethyl)aminophenyle utilises comme agents antiviraux et antitumoraux

Publications (1)

Publication Number	Publication Date
JPH10506410A true JPH10506410A (ja)	1998-06-23

Family

ID=10778062

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP9506209A Pending JPH10506410A (ja)	1995-07-21	1996-06-19	抗腫瘍剤及び抗ウイルス剤としてのビス−（２−ハロエチル）アミノフェニル置換ジスタマイシン誘導体

Country Status (18)

Country	Link
EP (1)	EP0787126A1 (fr)
JP (1)	JPH10506410A (fr)
KR (1)	KR970706251A (fr)
CN (1)	CN1159183A (fr)
AR (1)	AR003456A1 (fr)
AU (1)	AU6357996A (fr)
BR (1)	BR9606528A (fr)
CA (1)	CA2199635A1 (fr)
EA (1)	EA000033B1 (fr)
GB (1)	GB9514993D0 (fr)
HU (1)	HUP9702393A3 (fr)
IL (1)	IL120342A0 (fr)
MX (1)	MX9701949A (fr)
NO (1)	NO971142D0 (fr)
PL (1)	PL319352A1 (fr)
TW (1)	TW367325B (fr)
WO (1)	WO1997003957A1 (fr)
ZA (1)	ZA965028B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0968186A1 (fr)	1996-02-26	2000-01-05	California Institute Of Technology	Polyamides ameliores pour assurer une liaison dans le sillon mineur de l'adn a double brins
US6635417B1 (en)	1996-07-31	2003-10-21	California Institute Of Technology	Complex formation between DSDNA and oligomer of cyclic heterocycles
US5998140A (en) *	1996-07-31	1999-12-07	The Scripps Research Institute	Complex formation between dsDNA and oligomer of cyclic heterocycles
GB9623522D0 (en) *	1996-11-11	1997-01-08	Pharmacia & Upjohn Spa	Benzoheterocycle distamycin derivatives process for preparing them and their use as antitumour and antiviral agents
GB9816652D0 (en) *	1998-07-30	1998-09-30	Pharmacia & Upjohn Spa	Sulfurated distamycin derivatives process for preparing them and their use as antitumor agents
GB9907414D0 (en) *	1999-03-31	1999-05-26	Cancer Res Campaign Tech	Improvements relating to prodrugs
US6559125B1 (en)	2000-01-28	2003-05-06	California Institute Of Technology	Polyamide-alkylator conjugates and related products and method
US20030236198A1 (en)	2001-06-13	2003-12-25	Genesoft, Inc.	Antipathogenic benzamide compounds
ATE425753T1 (de)	2002-08-02	2009-04-15	Genesoft Pharmaceuticals Inc	Biaryl-verbindungen mit antiinfektiver wirkung
EP1562931A2 (fr)	2002-10-25	2005-08-17	Genesoft Pharmaceuticals, Inc.	Composes biaryle anti-infectieux
JP2006509027A (ja)	2002-12-10	2006-03-16	オーシェントファーマシューティカルズコーポレーション	（ピロールカルボキサミド）−（ベンズアミド）−（イミダゾールカルボキサミド）モチーフを有する抗菌化合物
EP2792355A1 (fr)	2013-04-17	2014-10-22	Albert-Ludwigs-Universität Freiburg	Composés destinés à être utilisés comme inhibiteurs de bromodomaine
CN115414356A (zh) *	2022-09-27	2022-12-02	广西科技大学	一种茚并吡咯类衍生物在制备抗肿瘤药物组合物中的应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8612218D0 (en) *	1986-05-20	1986-06-25	Erba Farmitalia	Site specific alkylating agents

1995
- 1995-07-21 GB GBGB9514993.6A patent/GB9514993D0/en active Pending
1996
- 1996-06-13 ZA ZA965028A patent/ZA965028B/xx unknown
- 1996-06-18 TW TW085107334A patent/TW367325B/zh active
- 1996-06-19 IL IL12034296A patent/IL120342A0/xx unknown
- 1996-06-19 JP JP9506209A patent/JPH10506410A/ja active Pending
- 1996-06-19 EA EA199700046A patent/EA000033B1/ru not_active IP Right Cessation
- 1996-06-19 BR BR9606528A patent/BR9606528A/pt not_active Application Discontinuation
- 1996-06-19 EP EP96922849A patent/EP0787126A1/fr not_active Withdrawn
- 1996-06-19 HU HU9702393A patent/HUP9702393A3/hu unknown
- 1996-06-19 CN CN96190784A patent/CN1159183A/zh active Pending
- 1996-06-19 AU AU63579/96A patent/AU6357996A/en not_active Abandoned
- 1996-06-19 WO PCT/EP1996/002659 patent/WO1997003957A1/fr not_active Ceased
- 1996-06-19 MX MX9701949A patent/MX9701949A/es unknown
- 1996-06-19 CA CA002199635A patent/CA2199635A1/fr not_active Abandoned
- 1996-06-19 PL PL96319352A patent/PL319352A1/xx unknown
- 1996-07-15 AR ARP960103583A patent/AR003456A1/es unknown
- 1996-09-19 KR KR1019970701796A patent/KR970706251A/ko not_active Withdrawn
1997
- 1997-03-12 NO NO971142A patent/NO971142D0/no unknown

Also Published As

Publication number	Publication date
PL319352A1 (en)	1997-08-04
HUP9702393A2 (hu)	1998-04-28
CN1159183A (zh)	1997-09-10
NO971142L (no)	1997-03-12
EA199700046A1 (ru)	1997-12-30
IL120342A0 (en)	1997-06-10
AU6357996A (en)	1997-02-18
ZA965028B (en)	1997-01-23
MX9701949A (es)	1997-06-28
CA2199635A1 (fr)	1997-02-06
TW367325B (en)	1999-08-21
BR9606528A (pt)	1997-12-23
WO1997003957A1 (fr)	1997-02-06
EA000033B1 (ru)	1998-02-26
GB9514993D0 (en)	1995-09-20
KR970706251A (ko)	1997-11-03
EP0787126A1 (fr)	1997-08-06
HUP9702393A3 (en)	1998-05-28
AR003456A1 (es)	1998-08-05
NO971142D0 (no)	1997-03-12

Publication	Publication Date	Title
EP0937070B1 (fr)	2003-12-03	Derives de la distamycine benzo-heterocyclique, leur procede de preparation et leur utilisation comme agents antitumoraux ou antiviraux
JPH0623193B2 (ja)	1994-03-30	新規なジスタマイシンａ同族体、その製造方法およびそれを含有する医薬組成物
JP2986208B2 (ja)	1999-12-06	アクリロイル基置換ピロール誘導体
CN108409663B (zh)	2021-09-03	微管抑制剂及其制备方法和用途
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