JPH11507369A - プレリポソーム凍結乾燥体から得られるサブミクロンリポソーム懸濁液 - Google Patents

プレリポソーム凍結乾燥体から得られるサブミクロンリポソーム懸濁液

Info

Publication number
JPH11507369A
JPH11507369A JP9502034A JP50203497A JPH11507369A JP H11507369 A JPH11507369 A JP H11507369A JP 9502034 A JP9502034 A JP 9502034A JP 50203497 A JP50203497 A JP 50203497A JP H11507369 A JPH11507369 A JP H11507369A
Authority
JP
Japan
Prior art keywords
surfactant
composition
liposome
submicron
lipid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP9502034A
Other languages
English (en)
Japanese (ja)
Other versions
JPH11507369A5 (2
Inventor
イーユ ツォウ
ワルドマー プリーブ
ソラー ロマン ペレス
Original Assignee
ボード オブ リージェンツ ザ ユニヴァーシティ オブ テキサス システム
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ボード オブ リージェンツ ザ ユニヴァーシティ オブ テキサス システム filed Critical ボード オブ リージェンツ ザ ユニヴァーシティ オブ テキサス システム
Publication of JPH11507369A publication Critical patent/JPH11507369A/ja
Publication of JPH11507369A5 publication Critical patent/JPH11507369A5/ja
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dispersion Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP9502034A 1995-06-06 1996-06-06 プレリポソーム凍結乾燥体から得られるサブミクロンリポソーム懸濁液 Ceased JPH11507369A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/468,791 1995-06-06
US08/468,791 US5902604A (en) 1995-06-06 1995-06-06 Submicron liposome suspensions obtained from preliposome lyophilizates
PCT/US1996/009830 WO1996039121A1 (en) 1995-06-06 1996-06-06 Submicron liposome suspensions obtained from preliposome lyophilizates

Publications (2)

Publication Number Publication Date
JPH11507369A true JPH11507369A (ja) 1999-06-29
JPH11507369A5 JPH11507369A5 (2) 2004-07-29

Family

ID=23861262

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9502034A Ceased JPH11507369A (ja) 1995-06-06 1996-06-06 プレリポソーム凍結乾燥体から得られるサブミクロンリポソーム懸濁液

Country Status (6)

Country Link
US (2) US5902604A (2)
EP (2) EP0831781A1 (2)
JP (1) JPH11507369A (2)
AU (1) AU710113B2 (2)
CA (1) CA2221341C (2)
WO (1) WO1996039121A1 (2)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012031200A (ja) * 2004-11-30 2012-02-16 Western Univ Of Health Sciences 被覆薬物送達製剤
JP2015193629A (ja) * 2009-06-03 2015-11-05 マヨ、ジョン、チャールズ 深部組織の痛みを治療するための製剤
US9555051B2 (en) 2012-03-29 2017-01-31 Sequessome Technology Holdings Limited Vesicular formulations
JP2017510662A (ja) * 2014-04-08 2017-04-13 アラダイム コーポレーション 非結核性抗酸菌に対する活性を有するリポソームシプロフロキサシン製剤
JP2017513839A (ja) * 2014-04-08 2017-06-01 アラダイム コーポレーション 凍結融解後に薬物ナノ結晶を形成するリポソーム
US10744090B2 (en) 2015-06-30 2020-08-18 Sequessome Technology Holdings Limited Multiphasic compositions
JP2022538865A (ja) * 2019-06-28 2022-09-06 ボード オブ レジェンツ，ザ ユニバーシティ オブ テキサス システム リポソーム化アナマイシン前駆体凍結乾燥物の調製
JP2023502253A (ja) * 2019-11-21 2023-01-23 ボード オブ レジェンツ，ザ ユニバーシティ オブ テキサス システム リポソームアナマイシンによる肺標的抗癌療法
JP2023523872A (ja) * 2019-06-28 2023-06-08 ボード オブ レジェンツ，ザ ユニバーシティ オブ テキサス システム リポソーム化アナマイシンを再構成する方法

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CA2318556A1 (en) * 1998-01-16 1999-07-22 Biomira, Inc. Lipomatrix preparation
AU773515B2 (en) * 1999-02-08 2004-05-27 Alza Corporation Method for controlling liposome size
WO2001032145A1 (en) * 1999-10-29 2001-05-10 Board Of Regents, The University Of Texas System Method of cancer treatment
EP1138312A1 (de) * 2000-03-28 2001-10-04 Primacare S.A. Pro-liposomen
US6761901B1 (en) 2000-05-02 2004-07-13 Enzrel Inc. Liposome drug delivery
US20020007055A1 (en) * 2000-05-15 2002-01-17 Hirotaka Uchiyama Compositions comprising cyclodextrin
CN1245153C (zh) * 2002-06-06 2006-03-15 上海家化联合股份有限公司 一种维生素a脂质体及其制备方法
WO2004022100A1 (en) * 2002-08-15 2004-03-18 Yunqing Liu Soild nano pharmaceutical formulation and preparation method thereof
AU2004235781A1 (en) * 2003-05-02 2004-11-18 Aronex Pharmaceuticals, Inc. Lipid platinum complexes and methods of use thereof
CA2525973A1 (en) * 2003-05-20 2004-12-09 Aronex Pharmaceuticals, Inc. Combination chemotherapy comprising capecitabine and a liposomal platinum complex
CA2526289A1 (en) * 2003-05-20 2004-12-02 Aronex Pharmaceuticals, Inc. Combination chemotherapy comprising 5-fluorouracil or a derivative thereof and a liposomal platinum complex
CA2525952A1 (en) * 2003-05-20 2004-12-09 Aronex Pharmaceuticals, Inc. Combination chemotherapy comprising gemcitabine and a liposomal platinum complex
EP1663153A4 (en) * 2003-05-20 2011-01-05 Aronex Pharmaceuticals Inc COMBINATION SCHEMOTHERAPY WITH A LIPOSOMAL PLATINUM COMPLEX
EP1643972A4 (en) * 2003-06-27 2010-01-20 Smithkline Beecham Corp STABILIZED LIPOSOMAL TOPOTECAN COMPOSITION AND METHOD
US20060002994A1 (en) * 2004-03-23 2006-01-05 Thomas James L Responsive liposomes for ultrasonic drug delivery
RU2542449C2 (ru) * 2007-11-30 2015-02-20 Эндо Фармасьютикалз Солюшнз Инк. Композиции и способы лечения рака мочевого пузыря
CA3044884A1 (en) * 2009-12-07 2011-06-16 Arbutus Biopharma Corporation Compositions for nucleic acid delivery
MX2016005232A (es) * 2013-10-22 2017-01-19 Aradigm Corp Formulaciones liposomicas para inhalacion, modificadas con agente tensoactivo, que proveen un perfil de liberacion tanto inmediata como sostenida.
US20160120806A1 (en) * 2014-04-08 2016-05-05 Aradigm Corporation Nanocrystals formed in a microenvironment
PH12022550592A1 (en) * 2016-01-07 2023-07-17 Tesorx Pharma Llc Formulations for treating bladder cancer
AU2017382281B2 (en) 2016-12-22 2024-07-11 Genentech, Inc. Methods and formulations for reducing reconstitution time of lyophilized polypeptides
US20200188298A1 (en) * 2018-12-14 2020-06-18 NuVessl, Inc. Method For Using Composition With Enhanced Passenger Molecule Loading

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GB1575343A (en) * 1977-05-10 1980-09-17 Ici Ltd Method for preparing liposome compositions containing biologically active compounds
US4201773A (en) * 1978-07-26 1980-05-06 The United States Of America As Represented By The Department Of Health, Education And Welfare 7-O-(2,6-Dideoxy-α-L-lyxo-hexopyranosyl)-daunomycinone, desmethoxy daunomycinone, adriamycinone, and carminomycinone
US4522803A (en) * 1983-02-04 1985-06-11 The Liposome Company, Inc. Stable plurilamellar vesicles, their preparation and use
BG38660A1 (en) * 1983-01-11 1986-02-14 Petkov Machine for hydroplastic processing of tube items
JPS6058915A (ja) * 1983-09-12 1985-04-05 Fujisawa Pharmaceut Co Ltd 薬物含有脂質小胞体製剤
JPS60155109A (ja) * 1984-01-23 1985-08-15 Terumo Corp リポソ−ム製剤
US4537882A (en) * 1984-05-10 1985-08-27 Ohio State University 4-Demethoxy-3'-desamino-2'-halo-anthracycline and pharmaceutical composition containing same
CA1264668C (en) * 1984-06-20 1990-01-23 EXTRUSION TECHNIQUES FOR THE PRODUCTION OF LIPOSOMES
ZW3385A1 (en) * 1985-03-01 1986-09-24 David John Fluck Liposomes,process for their preparation and compositions containing them
US4975282A (en) * 1985-06-26 1990-12-04 The Liposome Company, Inc. Multilamellar liposomes having improved trapping efficiencies
GB8516859D0 (en) 1985-07-03 1985-08-07 Secretary Trade Ind Brit Cam follower mechanisms
DE3689769T2 (de) * 1985-07-05 1994-07-21 Liposome Co Inc Multilamellare liposome mit verbesserter einschliessungswirkung.
JPS6295134A (ja) * 1985-10-21 1987-05-01 Nippon Saafuakutanto Kogyo Kk リポソ−ムの製造法
US4812312A (en) * 1987-03-03 1989-03-14 Board Of Regents Of The University Of Texas System Liposome-incorporated nystatin
NZ223660A (en) * 1987-03-05 1990-11-27 Liposome Co Inc Low toxicity drug-lipid complexes; methods of making them; and method of determining their toxicity
US4855090A (en) * 1987-03-13 1989-08-08 Micro-Pak, Inc. Method of producing high aqueous volume multilamellar vesicles
US4911928A (en) * 1987-03-13 1990-03-27 Micro-Pak, Inc. Paucilamellar lipid vesicles
US5811119A (en) * 1987-05-19 1998-09-22 Board Of Regents, The University Of Texas Formulation and use of carotenoids in treatment of cancer
US4863739A (en) * 1987-05-19 1989-09-05 Board Of Regents, The University Of Texas System Liposome compositions of anthracycline derivatives
US5178875A (en) * 1991-01-14 1993-01-12 The Board Of Regents, The University Of Texas System Liposomal-polyene preliposomal powder and method for its preparation
US4950432A (en) * 1987-10-16 1990-08-21 Board Of Regents, The University Of Texas System Polyene microlide pre-liposomal powders
JPH03502327A (ja) * 1988-01-19 1991-05-30 ボード・オブ・リージェンツ，ザ・ユニバーシティ・オブ・テキサス・システム ３’‐デアミノドキソルビシンのエステル体、そのリポソーム組成物およびその使用方法
CA1335077C (en) * 1988-02-08 1995-04-04 Henri Isliker Process for the manufacture of apolipoproteins from human blood plasma or serum
CA1340241C (en) * 1988-06-08 1998-12-15 Fountain Pharmaceuticals, Inc. Method for marking solvent dilution microcarriers
US4999199A (en) * 1988-11-10 1991-03-12 Board Of Regents, The University Of Texas System Pharmaceutical formulations: liposomes incorporating aromatic polyene antibiotics
US5032404A (en) * 1989-02-23 1991-07-16 Board Of Regents, The University Of Texas System Lipsome-incorporation of polyenes
US5585112A (en) * 1989-12-22 1996-12-17 Imarx Pharmaceutical Corp. Method of preparing gas and gaseous precursor-filled microspheres
JPH06183953A (ja) * 1991-06-24 1994-07-05 Nippon Oil & Fats Co Ltd 混合脂質膜小胞
JPH06293615A (ja) * 1992-08-25 1994-10-21 Nippon Oil & Fats Co Ltd 混合脂質膜小胞を含有する化粧品
JPH06227966A (ja) * 1993-01-29 1994-08-16 Advanced Sukin Res Kenkyusho:Kk 温度感受性リポソーム製剤
FR2700954B1 (fr) * 1993-01-29 1995-04-28 Eve International Sa Composition cosmétique à action réparatrice et protectrice des cheveux secs et très secs.
DE4306475A1 (de) * 1993-03-02 1994-09-08 Ensenat Pedro Gonzalez Liposomen, enthaltend Chlorhexidindiacetat oder Chlorhexidindigluconat
CA2163860A1 (en) * 1993-06-30 1995-01-12 Chung C. Hsu Method for preparing liposomes
US5820880A (en) * 1995-06-07 1998-10-13 The United States Of America As Represented By The Secretary Of The Army Liposomal formulation

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012031200A (ja) * 2004-11-30 2012-02-16 Western Univ Of Health Sciences 被覆薬物送達製剤
JP2015193629A (ja) * 2009-06-03 2015-11-05 マヨ、ジョン、チャールズ 深部組織の痛みを治療するための製剤
US9555051B2 (en) 2012-03-29 2017-01-31 Sequessome Technology Holdings Limited Vesicular formulations
JP2017510662A (ja) * 2014-04-08 2017-04-13 アラダイム コーポレーション 非結核性抗酸菌に対する活性を有するリポソームシプロフロキサシン製剤
JP2017513839A (ja) * 2014-04-08 2017-06-01 アラダイム コーポレーション 凍結融解後に薬物ナノ結晶を形成するリポソーム
US10376508B2 (en) 2014-04-08 2019-08-13 Aradigm Corporation Liposomal ciprofloxacin formulations with activity against non-tuberculous mycobacteria
US11116765B2 (en) 2014-04-08 2021-09-14 Grifols, S.A. Liposomal ciprofloxacin formulations with activity against non-tuberculous mycobacteria
US10744090B2 (en) 2015-06-30 2020-08-18 Sequessome Technology Holdings Limited Multiphasic compositions
US11547665B2 (en) 2015-06-30 2023-01-10 Sequessome Technology Holdings Limited Multiphasic compositions
JP2022538865A (ja) * 2019-06-28 2022-09-06 ボード オブ レジェンツ，ザ ユニバーシティ オブ テキサス システム リポソーム化アナマイシン前駆体凍結乾燥物の調製
JP2023523872A (ja) * 2019-06-28 2023-06-08 ボード オブ レジェンツ，ザ ユニバーシティ オブ テキサス システム リポソーム化アナマイシンを再構成する方法
JP2023502253A (ja) * 2019-11-21 2023-01-23 ボード オブ レジェンツ，ザ ユニバーシティ オブ テキサス システム リポソームアナマイシンによる肺標的抗癌療法

Also Published As

Publication number Publication date
AU6108796A (en) 1996-12-24
WO1996039121A1 (en) 1996-12-12
AU710113B2 (en) 1999-09-16
US7238366B1 (en) 2007-07-03
EP1800665A3 (en) 2008-06-04
US5902604A (en) 1999-05-11
EP0831781A1 (en) 1998-04-01
CA2221341C (en) 2009-04-21
EP1800665A2 (en) 2007-06-27
CA2221341A1 (en) 1996-12-12

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