Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aska Pharmaceutical Co Ltd
Teikoku Chemical Industry Co Ltd
Original Assignee
Teikoku Chemical Industry Co Ltd
Teikoku Hormone Manufacturing Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teikoku Chemical Industry Co Ltd, Teikoku Hormone Manufacturing Co LtdfiledCriticalTeikoku Chemical Industry Co Ltd
Priority to JP13280978ApriorityCriticalpatent/JPS5559164A/en
Publication of JPS5559164ApublicationCriticalpatent/JPS5559164A/en
USE: They have spasmolytic and analgesic activities and the use as a agent for analgesic and spasmolytic effect is expected. Further some of them are used as an intermediate of sulpiride that is used as remedy for ulcer.
PREPARATION: 2-N-Ethlpyrrolidinylidene- [2'-methoxy-5'- (N'-ethlpyrrolidinylidene) sulfamoyl] hippuric ethyl of formula II is heated in water or an alcohol with aqueous mineral acid under reflux to give the objective compound of formula I. The concentration of the aqueous mineral acid is preferably 8W3 normal from the view point of operation.
COPYRIGHT: (C)1980,JPO&Japio
JP13280978A1978-10-271978-10-27Benzamide derivative and its production
PendingJPS5559164A
(en)