JPS6144890A - 含フツ素メトトレキサ−ト誘導体 - Google Patents

含フツ素メトトレキサ−ト誘導体

Info

Publication number
JPS6144890A
JPS6144890A JP16691184A JP16691184A JPS6144890A JP S6144890 A JPS6144890 A JP S6144890A JP 16691184 A JP16691184 A JP 16691184A JP 16691184 A JP16691184 A JP 16691184A JP S6144890 A JPS6144890 A JP S6144890A
Authority
JP
Japan
Prior art keywords
water
formula
methyl
added
mixture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP16691184A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0533230B2 (2
Inventor
Tadahiko Tsushima
津島　忠彦
Kenji Kawada
健司 川田
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Priority to JP16691184A priority Critical patent/JPS6144890A/ja
Publication of JPS6144890A publication Critical patent/JPS6144890A/ja
Publication of JPH0533230B2 publication Critical patent/JPH0533230B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP16691184A 1984-08-08 1984-08-08 含フツ素メトトレキサ−ト誘導体 Granted JPS6144890A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP16691184A JPS6144890A (ja) 1984-08-08 1984-08-08 含フツ素メトトレキサ−ト誘導体

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP16691184A JPS6144890A (ja) 1984-08-08 1984-08-08 含フツ素メトトレキサ−ト誘導体

Publications (2)

Publication Number Publication Date
JPS6144890A true JPS6144890A (ja) 1986-03-04
JPH0533230B2 JPH0533230B2 (2) 1993-05-19

Family

ID=15839924

Family Applications (1)

Application Number Title Priority Date Filing Date
JP16691184A Granted JPS6144890A (ja) 1984-08-08 1984-08-08 含フツ素メトトレキサ−ト誘導体

Country Status (1)

Country Link
JP (1) JPS6144890A (2)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01270872A (ja) * 1988-02-16 1989-10-30 Becton Dickinson & Co 潤滑化された表面の作製法
JP2012505186A (ja) * 2008-10-10 2012-03-01 メルク・アンド・コンパニー Ｐｅｔ用放射性トレーサーとしての１８ｆ標識葉酸
US8344140B2 (en) 2007-04-11 2013-01-01 Merck Eprova Ag 18F-labelled folates
US10377756B2 (en) 2007-04-11 2019-08-13 Merck & Cie 18F-labelled folates

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ANN.N.Y.ACAD.SCI=1971 *
J.MED.CHEM=1983 *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01270872A (ja) * 1988-02-16 1989-10-30 Becton Dickinson & Co 潤滑化された表面の作製法
US8344140B2 (en) 2007-04-11 2013-01-01 Merck Eprova Ag 18F-labelled folates
US10377756B2 (en) 2007-04-11 2019-08-13 Merck & Cie 18F-labelled folates
JP2012505186A (ja) * 2008-10-10 2012-03-01 メルク・アンド・コンパニー Ｐｅｔ用放射性トレーサーとしての１８ｆ標識葉酸
US10961246B2 (en) 2008-10-10 2021-03-30 Merck & Cie 18F-labelled folates as PET radiotracers

Also Published As

Publication number Publication date
JPH0533230B2 (2) 1993-05-19

Similar Documents

Publication Publication Date Title
CN113227071B (zh) 治疗与IL-12、IL-23和/或IFN-α的调节相关的病症的酰胺取代的杂环化合物
JP6843135B2 (ja) ＩＬ−１２、ＩＬ−２３および／またはＩＦＮα応答のモジュレーターとして有用なイミダゾピリダジン化合物
JP3301024B2 (ja) グリシンレセプター拮抗物質及びその用途
ES3035735T3 (en) Amide-disubstituted pyridine or pyridazine compounds
AU2023307538A1 (en) Pyrrolotriazine and imidazotriazine derivatives as modulators of the nlrp3 inflammasome pathway
JPH0211546A (ja) ガバペンチン１水化物およびその製法
EP3986879B1 (en) Fused 1,2-thiazoles and 1,2-thiazines which act as nlrp3 modulators
KR20060134179A (ko) 트리(사이클로) 치환된 아미드 화합물
JPS63152388A (ja) 新規なセフェム化合物
EP3448375B1 (en) Benzoylglycine derivatives and methods of making and using same
JPH10182583A (ja) 新規ヒドロキサム酸誘導体
JP7618642B2 (ja) インターロイキンの調節におけるプロドラッグ
JPH0150698B2 (2)
JPH03101643A (ja) ハロゲノアルキルフェニルアルコール、ケトンおよびそれらの水和物
JPS6144890A (ja) 含フツ素メトトレキサ−ト誘導体
JP2686887B2 (ja) ピペリジノ−３，４−ジヒドロカルボスチリル誘導体
CN118541366A (zh) 二氢噁唑衍生物化合物
US4416882A (en) Di(alkylamino) derivatives of chloronitropyrazines useful as adjuncts to radiation therapy
JPH07242670A (ja) ピロロ［３，２−ｅ］ピラゾロ［１，５−ａ］ピリミジン誘導体及びこれを含有する循環器系疾患治療剤
JPH10237028A (ja) Ｎｏｓ阻害作用を有する芳香族アミン誘導体
JPH11512734A (ja) Ｐｎｐインヒビターとしてのプリンとグアニンの誘導体
JPS61140587A (ja) チアゾロ［３，２‐ａ］ピリミジンの光学異性体、その製法と使用
JPH0395166A (ja) イソキサゾロン誘導体含有脳機能改善剤
JPH03130255A (ja) アニリン誘導体およびそれを有効成分とする抗炎症剤
JPS634829B2 (2)

Legal Events

Date Code Title Description
EXPY Cancellation because of completion of term