JPS63208520A - ピラジン誘導体を含有する血小板凝集抑制剤 - Google Patents

ピラジン誘導体を含有する血小板凝集抑制剤

Info

Publication number
JPS63208520A
JPS63208520A JP4155087A JP4155087A JPS63208520A JP S63208520 A JPS63208520 A JP S63208520A JP 4155087 A JP4155087 A JP 4155087A JP 4155087 A JP4155087 A JP 4155087A JP S63208520 A JPS63208520 A JP S63208520A
Authority
JP
Japan
Prior art keywords
formula
blood platelet
pyrazine derivative
expressed
platelet agglutination
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP4155087A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0575728B2 (it
Inventor
Toshio Wakabayashi
若林　利生
Akihiro Ota
明廣 太田
Yasuo Akita
秋田　安男
Norihiro Watanabe
渡辺　徳弘
Hirokazu Hasegawa
弘和 長谷川
Michifumi Yaguchi
理史 矢口
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Terumo Corp
Original Assignee
Terumo Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Terumo Corp filed Critical Terumo Corp
Priority to JP4155087A priority Critical patent/JPS63208520A/ja
Publication of JPS63208520A publication Critical patent/JPS63208520A/ja
Publication of JPH0575728B2 publication Critical patent/JPH0575728B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP4155087A 1987-02-26 1987-02-26 ピラジン誘導体を含有する血小板凝集抑制剤 Granted JPS63208520A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP4155087A JPS63208520A (ja) 1987-02-26 1987-02-26 ピラジン誘導体を含有する血小板凝集抑制剤

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4155087A JPS63208520A (ja) 1987-02-26 1987-02-26 ピラジン誘導体を含有する血小板凝集抑制剤

Publications (2)

Publication Number Publication Date
JPS63208520A true JPS63208520A (ja) 1988-08-30
JPH0575728B2 JPH0575728B2 (it) 1993-10-21

Family

ID=12611534

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4155087A Granted JPS63208520A (ja) 1987-02-26 1987-02-26 ピラジン誘導体を含有する血小板凝集抑制剤

Country Status (1)

Country Link
JP (1) JPS63208520A (it)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013526540A (ja) * 2010-05-12 2013-06-24 バーテックス ファーマシューティカルズ インコーポレイテッド Ａｔｒキナーゼ阻害剤として有用な化合物
US9630956B2 (en) 2010-05-12 2017-04-25 Vertex Pharmaceuticals Incorporated Compounds useful as inhibitors of ATR kinase
US9701674B2 (en) 2008-12-19 2017-07-11 Vertex Pharmaceuticals Incorporated Substituted pyrazines as ATR kinase inhibitors
US9791456B2 (en) 2012-10-04 2017-10-17 Vertex Pharmaceuticals Incorporated Method for measuring ATR inhibition mediated increases in DNA damage
US9862709B2 (en) 2011-09-30 2018-01-09 Vertex Pharmaceuticals Incorporated Processes for making compounds useful as inhibitors of ATR kinase
US10478430B2 (en) 2012-04-05 2019-11-19 Vertex Pharmaceuticals Incorporated Compounds useful as inhibitors of ATR kinase and combination therapies thereof
US10813929B2 (en) 2011-09-30 2020-10-27 Vertex Pharmaceuticals Incorporated Treating cancer with ATR inhibitors
US11464774B2 (en) 2015-09-30 2022-10-11 Vertex Pharmaceuticals Incorporated Method for treating cancer using a combination of DNA damaging agents and ATR inhibitors

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10479784B2 (en) 2008-12-19 2019-11-19 Vertex Pharmaceuticals Incorporated Substituted pyrazin-2-amines as inhibitors of ATR kinase
US9701674B2 (en) 2008-12-19 2017-07-11 Vertex Pharmaceuticals Incorporated Substituted pyrazines as ATR kinase inhibitors
US10961232B2 (en) 2008-12-19 2021-03-30 Vertex Pharmaceuticals Incorporated Substituted pyrazines as ATR kinase inhibitors
US9630956B2 (en) 2010-05-12 2017-04-25 Vertex Pharmaceuticals Incorporated Compounds useful as inhibitors of ATR kinase
JP2013526540A (ja) * 2010-05-12 2013-06-24 バーテックス ファーマシューティカルズ インコーポレイテッド Ａｔｒキナーゼ阻害剤として有用な化合物
US10822331B2 (en) 2011-09-30 2020-11-03 Vertex Pharmaceuticals Incorporated Processes for preparing ATR inhibitors
US10208027B2 (en) 2011-09-30 2019-02-19 Vertex Pharmaceuticals Incorporated Processes for preparing ATR inhibitors
US10813929B2 (en) 2011-09-30 2020-10-27 Vertex Pharmaceuticals Incorporated Treating cancer with ATR inhibitors
US9862709B2 (en) 2011-09-30 2018-01-09 Vertex Pharmaceuticals Incorporated Processes for making compounds useful as inhibitors of ATR kinase
US10478430B2 (en) 2012-04-05 2019-11-19 Vertex Pharmaceuticals Incorporated Compounds useful as inhibitors of ATR kinase and combination therapies thereof
US11110086B2 (en) 2012-04-05 2021-09-07 Vertex Pharmaceuticals Incorporated Compounds useful as inhibitors of ATR kinase and combination therapies thereof
US9791456B2 (en) 2012-10-04 2017-10-17 Vertex Pharmaceuticals Incorporated Method for measuring ATR inhibition mediated increases in DNA damage
US11464774B2 (en) 2015-09-30 2022-10-11 Vertex Pharmaceuticals Incorporated Method for treating cancer using a combination of DNA damaging agents and ATR inhibitors

Also Published As

Publication number Publication date
JPH0575728B2 (it) 1993-10-21

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