JPS6354320A - 抗アルコ−ル症組成物 - Google Patents
抗アルコ−ル症組成物Info
- Publication number
- JPS6354320A JPS6354320A JP61199448A JP19944886A JPS6354320A JP S6354320 A JPS6354320 A JP S6354320A JP 61199448 A JP61199448 A JP 61199448A JP 19944886 A JP19944886 A JP 19944886A JP S6354320 A JPS6354320 A JP S6354320A
- Authority
- JP
- Japan
- Prior art keywords
- glutamine
- alanine
- alcohol
- group
- administration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 19
- 230000002075 anti-alcohol Effects 0.000 title abstract description 3
- 201000010099 disease Diseases 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 2
- QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 claims abstract description 28
- 235000004279 alanine Nutrition 0.000 claims abstract description 27
- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 claims abstract description 25
- 150000003839 salts Chemical class 0.000 claims abstract description 9
- 208000007848 Alcoholism Diseases 0.000 claims description 4
- 201000007930 alcohol dependence Diseases 0.000 claims description 4
- ZDXPYRJPNDTMRX-VKHMYHEASA-N L-glutamine Chemical compound OC(=O)[C@@H](N)CCC(N)=O ZDXPYRJPNDTMRX-VKHMYHEASA-N 0.000 abstract description 16
- 235000013305 food Nutrition 0.000 abstract description 13
- 239000003814 drug Substances 0.000 abstract description 4
- 235000011194 food seasoning agent Nutrition 0.000 abstract description 2
- 235000018102 proteins Nutrition 0.000 abstract description 2
- 108090000623 proteins and genes Proteins 0.000 abstract description 2
- 102000004169 proteins and genes Human genes 0.000 abstract description 2
- 239000000126 substance Substances 0.000 abstract description 2
- 239000000463 material Substances 0.000 abstract 3
- 229940079593 drug Drugs 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 41
- 235000001014 amino acid Nutrition 0.000 description 16
- 229940024606 amino acid Drugs 0.000 description 16
- 150000001413 amino acids Chemical class 0.000 description 16
- 241001465754 Metazoa Species 0.000 description 11
- 230000000694 effects Effects 0.000 description 11
- 239000000243 solution Substances 0.000 description 11
- 239000008280 blood Substances 0.000 description 8
- 210000004369 blood Anatomy 0.000 description 8
- 235000002639 sodium chloride Nutrition 0.000 description 6
- 235000000346 sugar Nutrition 0.000 description 5
- 201000004384 Alopecia Diseases 0.000 description 4
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- 208000024963 hair loss Diseases 0.000 description 4
- 230000003676 hair loss Effects 0.000 description 4
- 238000002360 preparation method Methods 0.000 description 4
- 125000003412 L-alanyl group Chemical group [H]N([H])[C@@](C([H])([H])[H])(C(=O)[*])[H] 0.000 description 3
- 241000699670 Mus sp. Species 0.000 description 3
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 3
- 229920002472 Starch Polymers 0.000 description 3
- 235000013527 bean curd Nutrition 0.000 description 3
- 230000003542 behavioural effect Effects 0.000 description 3
- 238000001802 infusion Methods 0.000 description 3
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- 235000019198 oils Nutrition 0.000 description 3
- 235000015067 sauces Nutrition 0.000 description 3
- 230000004580 weight loss Effects 0.000 description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- AHLPHDHHMVZTML-BYPYZUCNSA-N L-Ornithine Chemical compound NCCC[C@H](N)C(O)=O AHLPHDHHMVZTML-BYPYZUCNSA-N 0.000 description 2
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 description 2
- AYFVYJQAPQTCCC-GBXIJSLDSA-N L-threonine Chemical compound C[C@@H](O)[C@H](N)C(O)=O AYFVYJQAPQTCCC-GBXIJSLDSA-N 0.000 description 2
- KZSNJWFQEVHDMF-BYPYZUCNSA-N L-valine Chemical compound CC(C)[C@H](N)C(O)=O KZSNJWFQEVHDMF-BYPYZUCNSA-N 0.000 description 2
- 206010067125 Liver injury Diseases 0.000 description 2
- AHLPHDHHMVZTML-UHFFFAOYSA-N Orn-delta-NH2 Natural products NCCCC(N)C(O)=O AHLPHDHHMVZTML-UHFFFAOYSA-N 0.000 description 2
- UTJLXEIPEHZYQJ-UHFFFAOYSA-N Ornithine Natural products OC(=O)C(C)CCCN UTJLXEIPEHZYQJ-UHFFFAOYSA-N 0.000 description 2
- 241000700159 Rattus Species 0.000 description 2
- 235000013334 alcoholic beverage Nutrition 0.000 description 2
- 230000037396 body weight Effects 0.000 description 2
- 208000019425 cirrhosis of liver Diseases 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 235000005911 diet Nutrition 0.000 description 2
- 230000037213 diet Effects 0.000 description 2
- 239000003925 fat Substances 0.000 description 2
- 231100000234 hepatic damage Toxicity 0.000 description 2
- 230000005764 inhibitory process Effects 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 230000008818 liver damage Effects 0.000 description 2
- 229960003104 ornithine Drugs 0.000 description 2
- 230000036470 plasma concentration Effects 0.000 description 2
- 235000019992 sake Nutrition 0.000 description 2
- 230000001953 sensory effect Effects 0.000 description 2
- 239000011780 sodium chloride Substances 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 235000019698 starch Nutrition 0.000 description 2
- 239000008107 starch Substances 0.000 description 2
- 210000001321 subclavian vein Anatomy 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- 208000022309 Alcoholic Liver disease Diseases 0.000 description 1
- 241000972773 Aulopiformes Species 0.000 description 1
- 241000282472 Canis lupus familiaris Species 0.000 description 1
- 235000002568 Capsicum frutescens Nutrition 0.000 description 1
- 101000957724 Catostomus commersonii Corticoliberin-1 Proteins 0.000 description 1
- 241000238366 Cephalopoda Species 0.000 description 1
- 241000555825 Clupeidae Species 0.000 description 1
- 235000016795 Cola Nutrition 0.000 description 1
- 244000228088 Cola acuminata Species 0.000 description 1
- 235000011824 Cola pachycarpa Nutrition 0.000 description 1
- AEMOLEFTQBMNLQ-AQKNRBDQSA-N D-glucopyranuronic acid Chemical compound OC1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O AEMOLEFTQBMNLQ-AQKNRBDQSA-N 0.000 description 1
- 239000004278 EU approved seasoning Substances 0.000 description 1
- 208000004930 Fatty Liver Diseases 0.000 description 1
- IAJILQKETJEXLJ-UHFFFAOYSA-N Galacturonsaeure Natural products O=CC(O)C(O)C(O)C(O)C(O)=O IAJILQKETJEXLJ-UHFFFAOYSA-N 0.000 description 1
- 108010010803 Gelatin Proteins 0.000 description 1
- 206010019708 Hepatic steatosis Diseases 0.000 description 1
- 208000013016 Hypoglycemia Diseases 0.000 description 1
- ODKSFYDXXFIFQN-BYPYZUCNSA-N L-arginine Chemical compound OC(=O)[C@@H](N)CCCN=C(N)N ODKSFYDXXFIFQN-BYPYZUCNSA-N 0.000 description 1
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 description 1
- ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 description 1
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 description 1
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 description 1
- COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 description 1
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 description 1
- 244000137850 Marrubium vulgare Species 0.000 description 1
- -1 Merck Substances 0.000 description 1
- 241001502129 Mullus Species 0.000 description 1
- 241000237502 Ostreidae Species 0.000 description 1
- 235000010627 Phaseolus vulgaris Nutrition 0.000 description 1
- 244000046052 Phaseolus vulgaris Species 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 229960003589 arginine hydrochloride Drugs 0.000 description 1
- 125000003118 aryl group Chemical group 0.000 description 1
- 235000013405 beer Nutrition 0.000 description 1
- 150000005693 branched-chain amino acids Chemical class 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 235000013351 cheese Nutrition 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- ZPUCINDJVBIVPJ-LJISPDSOSA-N cocaine Chemical compound O([C@H]1C[C@@H]2CC[C@@H](N2C)[C@H]1C(=O)OC)C(=O)C1=CC=CC=C1 ZPUCINDJVBIVPJ-LJISPDSOSA-N 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 239000008298 dragée Substances 0.000 description 1
- 235000015071 dressings Nutrition 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 208000010706 fatty liver disease Diseases 0.000 description 1
- 230000037406 food intake Effects 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- 230000003087 glucogenic effect Effects 0.000 description 1
- 229940097043 glucuronic acid Drugs 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 230000002440 hepatic effect Effects 0.000 description 1
- 230000002218 hypoglycaemic effect Effects 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 230000035987 intoxication Effects 0.000 description 1
- 231100000566 intoxication Toxicity 0.000 description 1
- 230000000873 masking effect Effects 0.000 description 1
- 239000008268 mayonnaise Substances 0.000 description 1
- 235000010746 mayonnaise Nutrition 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 235000020636 oyster Nutrition 0.000 description 1
- 210000004738 parenchymal cell Anatomy 0.000 description 1
- 238000007911 parenteral administration Methods 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 235000013606 potato chips Nutrition 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 235000019685 rice crackers Nutrition 0.000 description 1
- 235000019515 salmon Nutrition 0.000 description 1
- 235000019512 sardine Nutrition 0.000 description 1
- 235000020083 shōchū Nutrition 0.000 description 1
- 235000014214 soft drink Nutrition 0.000 description 1
- 235000013555 soy sauce Nutrition 0.000 description 1
- 235000011496 sports drink Nutrition 0.000 description 1
- 231100000240 steatosis hepatitis Toxicity 0.000 description 1
- 239000007940 sugar coated tablet Substances 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 235000015193 tomato juice Nutrition 0.000 description 1
- 235000021419 vinegar Nutrition 0.000 description 1
- 239000000052 vinegar Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 235000015041 whisky Nutrition 0.000 description 1
- 235000014101 wine Nutrition 0.000 description 1
Landscapes
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61199448A JPS6354320A (ja) | 1986-08-26 | 1986-08-26 | 抗アルコ−ル症組成物 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61199448A JPS6354320A (ja) | 1986-08-26 | 1986-08-26 | 抗アルコ−ル症組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6354320A true JPS6354320A (ja) | 1988-03-08 |
| JPH0420409B2 JPH0420409B2 (fr) | 1992-04-02 |
Family
ID=16407982
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP61199448A Granted JPS6354320A (ja) | 1986-08-26 | 1986-08-26 | 抗アルコ−ル症組成物 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6354320A (fr) |
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6339104B1 (en) | 1998-04-16 | 2002-01-15 | The City Of Osaka | Therapeutic agent for primary biliary cirrhosis |
| JP2002226369A (ja) * | 2001-01-30 | 2002-08-14 | Otsuka Pharmaceut Co Ltd | グルタミン含有経口組成物 |
| WO2002074302A1 (fr) * | 2001-03-15 | 2002-09-26 | Riken | Compositions d'acides amines utilisees pour ameliorer l'insuffisance hepatique |
| WO2002098405A1 (fr) * | 2001-06-05 | 2002-12-12 | Ajinomoto Co., Inc. | Inhibiteurs de fibrose du foie |
| WO2003088987A1 (fr) * | 2002-04-19 | 2003-10-30 | Sanwa Shurui Co., Ltd. | Composition obtenue a partir de vinasse de distillerie de shochu d'orge, inhibant l'apparition de lesions hepatiques alcooliques, guerissant ces dernieres et ayant un gout agreable, ainsi que son procede de production |
| WO2005058306A1 (fr) * | 2003-12-16 | 2005-06-30 | Riken | Composition ou solution d'acides amines engendrant de l'energie et contenant de la glutamine |
| JP5801515B1 (ja) * | 2014-05-08 | 2015-10-28 | アサヒグループホールディングス株式会社 | トマト含有飲食品 |
| JP2016086715A (ja) * | 2014-10-31 | 2016-05-23 | アサヒグループホールディングス株式会社 | ニンジン由来成分含有飲食品 |
| WO2016103544A1 (fr) * | 2014-12-22 | 2016-06-30 | アサヒグループホールディングス株式会社 | Aliment ou boisson contenant des fibres alimentaires |
| JP2016119880A (ja) * | 2014-12-25 | 2016-07-07 | アサヒグループホールディングス株式会社 | 野菜由来成分含有飲食品 |
| CN107177430A (zh) * | 2017-07-05 | 2017-09-19 | 无锡丝润生物技术有限公司 | 一种富含蚕蛹氨基酸的啤酒及生产工艺 |
-
1986
- 1986-08-26 JP JP61199448A patent/JPS6354320A/ja active Granted
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6339104B1 (en) | 1998-04-16 | 2002-01-15 | The City Of Osaka | Therapeutic agent for primary biliary cirrhosis |
| JP2002226369A (ja) * | 2001-01-30 | 2002-08-14 | Otsuka Pharmaceut Co Ltd | グルタミン含有経口組成物 |
| WO2002074302A1 (fr) * | 2001-03-15 | 2002-09-26 | Riken | Compositions d'acides amines utilisees pour ameliorer l'insuffisance hepatique |
| WO2002098405A1 (fr) * | 2001-06-05 | 2002-12-12 | Ajinomoto Co., Inc. | Inhibiteurs de fibrose du foie |
| WO2003088987A1 (fr) * | 2002-04-19 | 2003-10-30 | Sanwa Shurui Co., Ltd. | Composition obtenue a partir de vinasse de distillerie de shochu d'orge, inhibant l'apparition de lesions hepatiques alcooliques, guerissant ces dernieres et ayant un gout agreable, ainsi que son procede de production |
| WO2005058306A1 (fr) * | 2003-12-16 | 2005-06-30 | Riken | Composition ou solution d'acides amines engendrant de l'energie et contenant de la glutamine |
| JP5801515B1 (ja) * | 2014-05-08 | 2015-10-28 | アサヒグループホールディングス株式会社 | トマト含有飲食品 |
| WO2015170605A1 (fr) * | 2014-05-08 | 2015-11-12 | アサヒグループホールディングス株式会社 | Aliment ou boisson contenant de la tomate |
| JP2016086715A (ja) * | 2014-10-31 | 2016-05-23 | アサヒグループホールディングス株式会社 | ニンジン由来成分含有飲食品 |
| WO2016103544A1 (fr) * | 2014-12-22 | 2016-06-30 | アサヒグループホールディングス株式会社 | Aliment ou boisson contenant des fibres alimentaires |
| JPWO2016103544A1 (ja) * | 2014-12-22 | 2017-09-28 | アサヒグループホールディングス株式会社 | 食物繊維含有飲食品 |
| JP2016119880A (ja) * | 2014-12-25 | 2016-07-07 | アサヒグループホールディングス株式会社 | 野菜由来成分含有飲食品 |
| CN107177430A (zh) * | 2017-07-05 | 2017-09-19 | 无锡丝润生物技术有限公司 | 一种富含蚕蛹氨基酸的啤酒及生产工艺 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0420409B2 (fr) | 1992-04-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EXPY | Cancellation because of completion of term |