LT3808B - Combinations of hepatitis c virus (hcv) antigens for use in immunoassays for anti-hcv antibodies - Google Patents

Combinations of hepatitis c virus (hcv) antigens for use in immunoassays for anti-hcv antibodies Download PDF

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Publication number
LT3808B
LT3808B LTIP1747A LTIP1747A LT3808B LT 3808 B LT3808 B LT 3808B LT IP1747 A LTIP1747 A LT IP1747A LT IP1747 A LTIP1747 A LT IP1747A LT 3808 B LT3808 B LT 3808B
Authority
LT
Lithuania
Prior art keywords
hcv
domain
antigen
cvh
avh
Prior art date
Application number
LTIP1747A
Other languages
English (en)
Lithuanian (lt)
Inventor
Michael Houghton
Qui-Lim Choo
George Kuo
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24005897&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LT3808(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chiron Corp filed Critical Chiron Corp
Publication of LTIP1747A publication Critical patent/LTIP1747A/xx
Publication of LT3808B publication Critical patent/LT3808B/lt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G01N33/5767—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pinball Game Machines (AREA)
  • Thermistors And Varistors (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
LTIP1747A 1990-04-04 1993-12-30 Combinations of hepatitis c virus (hcv) antigens for use in immunoassays for anti-hcv antibodies LT3808B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US50435290A 1990-04-04 1990-04-04

Publications (2)

Publication Number Publication Date
LTIP1747A LTIP1747A (en) 1995-07-25
LT3808B true LT3808B (en) 1996-03-25

Family

ID=24005897

Family Applications (1)

Application Number Title Priority Date Filing Date
LTIP1747A LT3808B (en) 1990-04-04 1993-12-30 Combinations of hepatitis c virus (hcv) antigens for use in immunoassays for anti-hcv antibodies

Country Status (25)

Country Link
EP (2) EP0693687B2 (fr)
JP (1) JP2733138B2 (fr)
KR (1) KR100206150B1 (fr)
AT (2) ATE139343T1 (fr)
BG (1) BG61291B1 (fr)
BR (1) BR9106309A (fr)
CY (1) CY1881A (fr)
DE (2) DE69131488T2 (fr)
DK (2) DK0450931T3 (fr)
ES (2) ES2088465T3 (fr)
FI (1) FI106317B (fr)
GB (1) GB2257784B (fr)
GR (2) GR3020964T3 (fr)
HU (1) HU217025B (fr)
IE (1) IE911105A1 (fr)
IL (2) IL97741A0 (fr)
LT (1) LT3808B (fr)
LV (2) LV10344A (fr)
MY (1) MY107499A (fr)
NO (1) NO310241B1 (fr)
PL (1) PL172133B1 (fr)
RO (1) RO109916B1 (fr)
RU (1) RU2130969C1 (fr)
UA (1) UA41266C2 (fr)
WO (1) WO1991015771A1 (fr)

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US6194140B1 (en) * 1990-04-04 2001-02-27 Chiron Corporation HCV NS3 protein fragments having helicase activity and improved solubility
CA2079912C (fr) * 1990-04-06 2000-07-11 Gregory Reyes Epitopes du virus de l'hepatite c
CA2049679C (fr) * 1990-08-24 2005-06-21 Sushil G. Devare Recherche des anticorps de l'hepatite c a l'aide d'antigenes recombinants
US6274148B1 (en) * 1990-11-08 2001-08-14 Chiron Corporation Hepatitis C virus asialoglycoproteins
EP0842947B2 (fr) * 1990-11-08 2009-03-18 Novartis Vaccines and Diagnostics, Inc. Asialoglycoproteines du virus de l'hepatite C
EP0754704B1 (fr) * 1990-12-14 1999-10-06 Innogenetics N.V. Antigènes synthétiques pour la détection des anticorps contre le virus l'hépatite C
US5910404A (en) 1990-12-14 1999-06-08 Innogenetics N.V. Synthetic antigens for the detection of antibodies to hepatitis C virus
US6007982A (en) * 1990-12-14 1999-12-28 Innogenetics N.V. Synthetic antigens for the detection of antibodies to hepatitis C virus
DE4041304A1 (de) * 1990-12-21 1992-06-25 Mikrogen Molekularbiol Entw Von strukturproteinen des hepatitis c-virus abgeleitete polypeptide, testkits, die diese polypeptide enthalten und impfstoffe gegen infektionen von hepatitis c-viren
US5574132A (en) * 1991-04-05 1996-11-12 Biochem Immunosystems Inc. Peptides and mixtures thereof for detecting antibodies to hepatitis C virus (HCV)
CA2099883A1 (fr) * 1991-11-07 1993-05-08 John A. Kink Cartographie de l'epitope de la region c33c du vhc
DE69232906T2 (de) * 1991-11-21 2004-01-15 Common Services Agency Edinbur Detektion des Hepatis-C Virus.
CA2128896A1 (fr) * 1992-02-04 1993-08-05 Douglas J. Jolly Traitement de l'hepatite
GB9203803D0 (en) * 1992-02-21 1992-04-08 Wellcome Found A recombinant polypeptide
UA39944C2 (uk) * 1992-07-07 2001-07-16 Чірон Корпорейшн Спосіб визначення ранньої сероконверсії у ссавця-хазяїна до вірусу гепатиту с і набір для використання в способі
US6153378A (en) * 1992-10-16 2000-11-28 Bionova Corporation Diagnosis of, and vaccination against, a positive stranded RNA virus using an isolated, unprocessed polypeptide encoded by a substantially complete genome of such virus
EP0593291A3 (fr) * 1992-10-16 1995-03-15 Evernew Biotech Inc Protéine nonstructurale du virus de l'hépatite C, et méthode diagnostique et nécessaire.
JP2778886B2 (ja) * 1992-10-16 1998-07-23 エバーニュー バイオテック インコーポレイティド Ｃ型肝炎ウィルスのコア抗原タンパク質及びそれを用いての診断方法及びキット
WO1994013164A1 (fr) 1992-12-10 1994-06-23 Nike International Ltd. Liaison caoutchouc-matiere plastique concernant des chaussures
KR100312534B1 (ko) 1993-04-28 2002-05-13 성재갑 씨(c)형간염및비(b)형간염동시측정면역블롯검정키트및면역블롯검정법
PT698216E (pt) * 1993-05-10 2005-03-31 Chiron Corp Metodos de tipificacao do virus da hepatite c e reagentes para utilizar nestes
DE4428705A1 (de) 1994-08-12 1996-02-15 Boehringer Mannheim Gmbh Rekombinantes Antigen aus der NS3-Region des Hepatitis C Virus
JPH0862219A (ja) * 1994-08-19 1996-03-08 Dainabotsuto Kk 還元型抗原に対する抗体アッセイ試薬及びそれを使用した測定方法
JP3665371B2 (ja) * 1994-08-31 2005-06-29 株式会社先端生命科学研究所 Ｃ型肝炎ウイルス感染又はグループ判定のためのエピトープキメラ抗原ペプチド、その製法、及びそれを使用する感染又はグループ判定法
CA2172305A1 (fr) * 1995-03-30 1996-10-01 Muneo Aoyama Peptide antigenique multiple, renfermant au moins deux peptides associes du virus de l'hepatite c
AU5924396A (en) * 1995-05-22 1996-12-11 Bionova Corporation Compositions and methods for the diagnosis of, and vaccinati on against, hepatitis c virus (hcv)
FR2734639B1 (fr) * 1995-05-26 1997-10-03 Parteurop Methode de pronostic de l'evolution d'une infection par le virus de l'hepatite c, et necessaire pour sa mise en oeuvre
FR2737209B1 (fr) 1995-07-25 1997-09-19 Bio Merieux Peptide capable d'etre reconnu par des anticorps reconnaissant l'antigene c33 du virus de l'hepatite c
US6127116A (en) * 1995-08-29 2000-10-03 Washington University Functional DNA clone for hepatitis C virus (HCV) and uses thereof
JP3715027B2 (ja) 1996-05-07 2005-11-09 シスメックス株式会社 Ｃ型肝炎ウイルス感染症診断薬
US7049428B1 (en) 1998-03-04 2006-05-23 Washington University HCV variants
US7338759B1 (en) 1997-03-04 2008-03-04 Washington University HCV variants
AU9497998A (en) * 1997-09-22 1999-04-12 Chiron Corporation Method for detecting antibodies in a sample
WO2001006252A2 (fr) * 1999-07-15 2001-01-25 Bayer Corporation Utilisation de titres d'anticorps specifiques pour predire une insuffisance hepatique chez des personnes infectees par le virus de l'hepatite c
CA2389206C (fr) * 1999-10-27 2011-01-04 Chiron Corporation Activation de lymphocytes t specifiques au virus de l'hepatite c
RU2179726C2 (ru) * 1999-11-17 2002-02-20 Государственный научный центр вирусологии и биотехнологии "Вектор" Способ изготовления контрольных панелей сывороток для контроля качества диагностики гепатита в
US6986892B1 (en) * 1999-11-24 2006-01-17 Chiron Corporation Immunogenic Hepatitis C virus non-structural polypeptides
CA2390082C (fr) * 1999-11-24 2010-06-29 Chiron Corporation Polypeptide non structurel du virus de l'hepatite c
US7491808B2 (en) 2000-06-15 2009-02-17 Novartis Vaccines And Diagnostics, Inc. HCV non-structural protein mutants and uses thereof
DK1354204T4 (da) 2000-06-15 2010-06-14 Novartis Vaccines & Diagnostic HCV-antigen/antistof-kombinationssay
RU2172489C1 (ru) * 2000-07-26 2001-08-20 Тверская государственная медицинская академия Способ диагностики множественной миеломы
RU2286172C2 (ru) 2000-08-17 2006-10-27 Трипеп Аб Вакцины, содержащие рибавирин, и способы их использования
US7022830B2 (en) 2000-08-17 2006-04-04 Tripep Ab Hepatitis C virus codon optimized non-structural NS3/4A fusion gene
US6680059B2 (en) 2000-08-29 2004-01-20 Tripep Ab Vaccines containing ribavirin and methods of use thereof
JP5175417B2 (ja) 2000-08-17 2013-04-03 トリペップ アクチ ボラゲット リバビリンを含むワクチンおよびその使用方法
FR2839722A1 (fr) 2002-05-17 2003-11-21 Bio Merieux Nouvelles compositions peptidiques et leur utilisation notamment dans la preparation de compositions pharmaceutiques actives contre le virus de l'hepatite c
RU2226694C2 (ru) * 2002-05-30 2004-04-10 Научно-исследовательский институт детских инфекций Способ дифференциальной диагностики вирусного гепатита с
ATE410693T1 (de) 2002-09-09 2008-10-15 Novartis Vaccines & Diagnostic Hcv-test
MXPA06014480A (es) * 2004-06-09 2007-03-21 Pathogen Removal And Diagnosti Particulas incluidas en un substrato poroso para la remocion de analitos objetivo de una muestra.
RU2262704C1 (ru) * 2004-10-06 2005-10-20 Общество с ограниченной ответственностью Научно-производственное объединение "Диагностические системы" Набор антигенов для определения антител к вирусу гепатита c "дс-hcv-антигены"
JP2005274584A (ja) * 2005-05-25 2005-10-06 Sysmex Corp Ｃ型肝炎ウイルス感染症診断薬の製造方法
JP4005093B2 (ja) * 2005-05-25 2007-11-07 シスメックス株式会社 Ｃ型肝炎ウイルス感染症診断薬および抗ｈｃｖ抗体検出方法
CA2618429A1 (fr) 2005-05-25 2007-03-22 Tripep Ab Gene de fusion ns3/4a non structurel de l'hepatite c
RU2327170C2 (ru) * 2006-02-27 2008-06-20 Закрытое акционерное общество "ДиТест" Способ комплексной диагностики вирусного гепатита в, вирусного гепатита с, вич-инфекции и сифилиса
ATE556136T1 (de) * 2006-03-09 2012-05-15 Transgene Sa Nichtstrukturelles hcv-fusionsprotein
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EP2185195A2 (fr) 2007-08-16 2010-05-19 Tripep Ab Plate-forme immunogène
FR2984328B1 (fr) 2011-12-20 2016-12-30 Bio-Rad Innovations Procede de detection d'une infection par le virus de l'hepatite c
CN107110868B (zh) * 2014-10-29 2020-08-21 雅培制药有限公司 采用ns3捕获肽的受试者抗hcv抗体检测测定
JP2018124277A (ja) * 2017-02-02 2018-08-09 三洋化成工業株式会社 粒子含有組成物、免疫測定用試薬、免疫測定方法及び粒子の保存方法

Citations (6)

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Publication number Priority date Publication date Assignee Title
US390599A (en) 1888-10-02 Tool for weaver s use
US456637A (en) 1891-07-28 Fence
US4255431A (en) 1978-04-14 1981-03-10 Aktiebolaget Hassle Gastric acid secretion inhibiting substituted 2-(2-benzimidazolyl)-pyridines, pharmaceutical preparations containing same, and method for inhibiting gastric acid secretion
US4751180A (en) 1985-03-28 1988-06-14 Chiron Corporation Expression using fused genes providing for protein product
EP0318216A1 (fr) 1987-11-18 1989-05-31 Chiron Corporation Diagnostics et vaccins de NANBV
US4870008A (en) 1983-08-12 1989-09-26 Chiron Corporation Secretory expression in eukaryotes

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CA1341482C (fr) † 1984-10-31 2005-05-10 Paul A. Luciw Procede de preparation de fragments de retrovirus du groupe du sida
KR0185373B1 (ko) † 1989-03-17 1999-05-01 로버트 피. 블랙버언 Hcv 폴리단백질에서 유래되는 hcv 아미노산 서열 부분을 포함하는 폴리펩티드 및 그 사용
BE1005485A5 (fr) * 1989-12-18 1993-08-10 Wellcome Found Agent viral.
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Patent Citations (6)

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US390599A (en) 1888-10-02 Tool for weaver s use
US456637A (en) 1891-07-28 Fence
US4255431A (en) 1978-04-14 1981-03-10 Aktiebolaget Hassle Gastric acid secretion inhibiting substituted 2-(2-benzimidazolyl)-pyridines, pharmaceutical preparations containing same, and method for inhibiting gastric acid secretion
US4870008A (en) 1983-08-12 1989-09-26 Chiron Corporation Secretory expression in eukaryotes
US4751180A (en) 1985-03-28 1988-06-14 Chiron Corporation Expression using fused genes providing for protein product
EP0318216A1 (fr) 1987-11-18 1989-05-31 Chiron Corporation Diagnostics et vaccins de NANBV

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Also Published As

Publication number Publication date
LV10344A (en) 1994-10-20
EP0693687B1 (fr) 1999-07-28
ATE139343T1 (de) 1996-06-15
JP2733138B2 (ja) 1998-03-30
NO923839D0 (no) 1992-10-01
EP0450931B1 (fr) 1996-06-12
DE69131488T2 (de) 1999-11-18
UA41266C2 (uk) 2001-09-17
AU639560B2 (en) 1993-07-29
PL172133B1 (pl) 1997-08-29
ATE182684T1 (de) 1999-08-15
GB2257784B (en) 1995-01-04
ES2088465T3 (es) 1996-08-16
IE911105A1 (en) 1991-10-09
GB9220480D0 (en) 1992-11-25
ES2134388T5 (es) 2008-12-01
DE69120138T2 (de) 1996-11-14
DK0693687T3 (da) 1999-11-29
HU9203146D0 (en) 1992-12-28
LV10344B (en) 1996-02-20
DK0693687T4 (da) 2008-09-22
BR9106309A (pt) 1993-04-20
HUT62706A (en) 1993-05-28
WO1991015771A1 (fr) 1991-10-17
JPH05508219A (ja) 1993-11-18
MY107499A (en) 1995-12-30
NO923839L (no) 1992-11-19
FI924349A0 (fi) 1992-09-28
LTIP1747A (en) 1995-07-25
GB2257784A (en) 1993-01-20
ES2134388T3 (es) 1999-10-01
RU2130969C1 (ru) 1999-05-27
DE69131488D1 (de) 1999-09-02
FI924349L (fi) 1992-09-28
KR100206150B1 (ko) 1999-07-01
EP0450931A1 (fr) 1991-10-09
NO310241B1 (no) 2001-06-11
RO109916B1 (ro) 1995-07-28
GR3031361T3 (en) 2000-01-31
EP0693687B2 (fr) 2008-06-04
IL170719A (en) 2011-04-28
BG61291B1 (en) 1997-04-30
IL97741A0 (en) 1992-06-21
AU7651091A (en) 1991-10-30
HU217025B (hu) 1999-11-29
DE69120138D1 (de) 1996-07-18
EP0693687A1 (fr) 1996-01-24
DK0450931T3 (da) 1996-07-01
CY1881A (en) 1996-04-05
BG96943A (bg) 1993-12-24
GR3020964T3 (en) 1996-12-31
FI106317B (fi) 2001-01-15

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Effective date: 20131230