LT4196479T - Pakeistieji piridotriazino junginiai ir jų panaudojimo būdai - Google Patents

Pakeistieji piridotriazino junginiai ir jų panaudojimo būdai

Info

Publication number
LT4196479T
LT4196479T LTEPPCT/US2022/012773T LTUS2022012773T LT4196479T LT 4196479 T LT4196479 T LT 4196479T LT US2022012773 T LTUS2022012773 T LT US2022012773T LT 4196479 T LT4196479 T LT 4196479T
Authority
LT
Lithuania
Prior art keywords
pyridotriazine
substituted
compounds
substituted pyridotriazine
pyridotriazine compounds
Prior art date
Application number
LTEPPCT/US2022/012773T
Other languages
English (en)
Inventor
Hang CHU
Ana Z. GONZALEZ BUENROSTRO
Hongyan Guo
Xiaochun Han
Anna E. Hurtley
Lan Jiang
Jiayao Li
David W. Lin
Michael L. Mitchell
Devan Naduthambi
Gregg M. SCHWARZWALDER
Suzanne M. SZEWCZYK
Matthew J. VON BARGEN
Qiaoyin Wu
Hong Yang
Jennifer R. Zhang
Original Assignee
Gilead Sciences, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gilead Sciences, Inc. filed Critical Gilead Sciences, Inc.
Publication of LT4196479T publication Critical patent/LT4196479T/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/18—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • AIDS & HIV (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
LTEPPCT/US2022/012773T 2021-01-19 2022-01-18 Pakeistieji piridotriazino junginiai ir jų panaudojimo būdai LT4196479T (lt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163139237P 2021-01-19 2021-01-19
US202163190461P 2021-05-19 2021-05-19
PCT/US2022/012773 WO2022159387A1 (en) 2021-01-19 2022-01-18 Substituted pyridotriazine compounds and uses thereof

Publications (1)

Publication Number Publication Date
LT4196479T true LT4196479T (lt) 2023-12-11

Family

ID=80514578

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEPPCT/US2022/012773T LT4196479T (lt) 2021-01-19 2022-01-18 Pakeistieji piridotriazino junginiai ir jų panaudojimo būdai

Country Status (26)

Country Link
US (4) US11613546B2 (lt)
EP (2) EP4196479B9 (lt)
JP (3) JP7591155B2 (lt)
KR (1) KR20230134529A (lt)
AU (2) AU2022210247C1 (lt)
CA (1) CA3202957A1 (lt)
CL (2) CL2023002074A1 (lt)
CO (1) CO2023009518A2 (lt)
CR (1) CR20230315A (lt)
DK (1) DK4196479T5 (lt)
DO (1) DOP2023000139A (lt)
ES (1) ES2968058T3 (lt)
FI (1) FI4196479T3 (lt)
HR (1) HRP20231654T2 (lt)
HU (1) HUE064467T2 (lt)
IL (1) IL304222A (lt)
LT (1) LT4196479T (lt)
MX (1) MX2023008137A (lt)
PE (2) PE20231297A1 (lt)
PL (1) PL4196479T3 (lt)
PT (1) PT4196479T (lt)
SA (1) SA523441639B1 (lt)
SI (1) SI4196479T1 (lt)
TW (2) TW202408533A (lt)
WO (1) WO2022159387A1 (lt)
ZA (1) ZA202306360B (lt)

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FI4196479T3 (fi) * 2021-01-19 2024-01-17 Gilead Sciences Inc Substituoituja pyridotriatsiiniyhdisteitä ja niiden käyttöjä
EP4384178A4 (en) * 2021-08-11 2025-07-02 Merck Sharp & Dohme Llc POLYCYCLIC CAP-DEPENDENT ENDONUCLEASE INHIBITORS FOR THE TREATMENT OR PREVENTION OF INFLUENZA
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