LTC2170860I2 - Benzimidazolo dariniai - Google Patents

Benzimidazolo dariniai

Info

Publication number: LTC2170860I2
Authority: LT; Lithuania
Prior art keywords: benzimidazole derivatives; benzimidazole; derivatives
Prior art date: 2007-06-29

Application number

LTPA2020528C

Other languages

English (en)

Original Assignee

Pfizer Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-06-29

Filing date

2020-08-26

Publication date

2022-03-10

2020-08-26 Application filed by Pfizer Inc. filed Critical Pfizer Inc.

2020-09-25 Publication of LTPA2020528I1 publication Critical patent/LTPA2020528I1/lt

2022-03-10 Publication of LTC2170860I2 publication Critical patent/LTC2170860I2/lt

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Hematology (AREA)
Oncology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

LTPA2020528C 2007-06-29 2020-08-26 Benzimidazolo dariniai LTC2170860I2 (lt)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US94728707P	2007-06-29	2007-06-29
US4164508P	2008-04-02	2008-04-02
PCT/IB2008/001575 WO2009004427A2 (en)	2007-06-29	2008-06-16	Benzimidazole derivatives

Publications (2)

Publication Number	Publication Date
LTPA2020528I1 LTPA2020528I1 (lt)	2020-09-25
LTC2170860I2 true LTC2170860I2 (lt)	2022-03-10

Family

ID=40161351

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
LTEP08762901.0T LT2170860T (lt)	2007-06-29	2008-06-16	Benzimidazolo dariniai
LTPA2020528C LTC2170860I2 (lt)	2007-06-29	2020-08-26	Benzimidazolo dariniai

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
LTEP08762901.0T LT2170860T (lt)	2007-06-29	2008-06-16	Benzimidazolo dariniai

Country Status (45)

Country	Link
US (2)	US8148401B2 (lt)
EP (1)	EP2170860B9 (lt)
JP (2)	JP4567099B2 (lt)
KR (1)	KR101143246B1 (lt)
CN (1)	CN101687841B (lt)
AP (1)	AP2377A (lt)
AR (1)	AR067346A1 (lt)
AU (1)	AU2008272641B2 (lt)
BR (1)	BRPI0813412B8 (lt)
CA (1)	CA2690953C (lt)
CL (1)	CL2008001922A1 (lt)
CO (1)	CO6160232A2 (lt)
CR (1)	CR11150A (lt)
CU (1)	CU23847B1 (lt)
CY (2)	CY1118650T1 (lt)
DK (1)	DK2170860T5 (lt)
DO (1)	DOP2009000278A (lt)
EA (1)	EA016888B1 (lt)
EC (1)	ECSP099803A (lt)
ES (1)	ES2609258T3 (lt)
FR (1)	FR20C1038I2 (lt)
GE (1)	GEP20125702B (lt)
GT (1)	GT200900328A (lt)
HN (1)	HN2008000974A (lt)
HR (1)	HRP20161562T2 (lt)
HU (2)	HUE030052T4 (lt)
IL (1)	IL202420A (lt)
LT (2)	LT2170860T (lt)
MA (1)	MA31466B1 (lt)
ME (1)	ME00962B (lt)
MY (1)	MY148636A (lt)
NI (1)	NI200900219A (lt)
NL (1)	NL301057I2 (lt)
NO (1)	NO2020027I1 (lt)
NZ (1)	NZ581889A (lt)
PA (1)	PA8785401A1 (lt)
PE (2)	PE20121010A1 (lt)
PL (1)	PL2170860T3 (lt)
PT (1)	PT2170860T (lt)
RS (1)	RS55395B9 (lt)
SI (1)	SI2170860T1 (lt)
TN (1)	TN2009000544A1 (lt)
TW (1)	TWI371451B (lt)
UY (1)	UY31164A1 (lt)
WO (1)	WO2009004427A2 (lt)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2609258T3 (es) *	2007-06-29	2017-04-19	Pfizer Inc.	Derivados de bencimidazol
CA2735593C (en)	2008-09-03	2017-08-15	Repligen Corporation	Compositions including 6-aminohexanoic acid derivatives as hdac inhibitors
CN102803246A (zh) *	2009-06-11	2012-11-28	锡耶纳生物技术股份公司	Hedgehog途径拮抗剂及其治疗应用
US8907089B2 (en)	2009-08-26	2014-12-09	Takeda Pharmaceutical Company Limited	Fused heterocyclic ring derivative and use thereof
US8628554B2 (en)	2010-06-13	2014-01-14	Virender K. Sharma	Intragastric device for treating obesity
US10010439B2 (en)	2010-06-13	2018-07-03	Synerz Medical, Inc.	Intragastric device for treating obesity
US9526648B2 (en)	2010-06-13	2016-12-27	Synerz Medical, Inc.	Intragastric device for treating obesity
US10420665B2 (en)	2010-06-13	2019-09-24	W. L. Gore & Associates, Inc.	Intragastric device for treating obesity
WO2012052948A1 (en)	2010-10-20	2012-04-26	Pfizer Inc.	Pyridine- 2- derivatives as smoothened receptor modulators
JP5452459B2 (ja)	2010-12-16	2014-03-26	株式会社Ｎｔｔドコモ	ホーム基地局及びハンドオーバ方法
EP3524324A1 (en)	2011-02-28	2019-08-14	BioMarin Pharmaceutical Inc.	Histone deacetylase inhibitors
US10059723B2 (en)	2011-02-28	2018-08-28	Biomarin Pharmaceutical Inc.	Histone deacetylase inhibitors
US8957066B2 (en)	2011-02-28	2015-02-17	Biomarin Pharmaceutical Inc.	Histone deacetylase inhibitors
WO2012122370A2 (en) *	2011-03-08	2012-09-13	Eutropics Pharmaceuticals, Inc.	Compositions and methods useful for treating diseases
FR2980477B1 (fr)	2011-09-23	2013-10-18	Centre Nat Rech Scient	Nouveaux composes modulateurs de la voie de signalisation des proteines hedgehog, leurs formes marquees, et applications
ES2612934T3 (es) *	2011-09-26	2017-05-19	Merck Patent Gmbh	Compuestos de piperidin bencilo como antagonista del receptor del ácido lisofosfatídico (LPA)
IN2014DN11205A (lt)	2012-06-20	2015-10-02	Eutropics Pharmaceuticals Inc
US20160038503A1 (en)	2012-11-21	2016-02-11	David Richard	Methods and compositions useful for treating diseases involving bcl-2 family proteins with isoquinoline and quinoline derivatives
US10029988B2 (en)	2013-03-15	2018-07-24	Biomarin Pharmaceutical Inc.	HDAC inhibitors
EP2996689A1 (en)	2013-04-17	2016-03-23	Albert-Ludwigs-Universität Freiburg	Compounds for use as bromodomain inhibitors
WO2015017788A1 (en)	2013-08-01	2015-02-05	Eutropics Pharmaceuticals, Inc.	Method for predicting cancer sensitivity
GB2519344A (en) *	2013-10-18	2015-04-22	Redx Pharma Ltd	Compounds
AU2014342269B2 (en)	2013-10-30	2020-02-27	Eutropics Pharmaceuticals, Inc.	Methods for determining chemosensitivity and chemotoxicity
HUE048664T2 (hu) *	2015-04-24	2020-07-28	Pfizer	1-((2R,4R)-2-(1H-benzo[D]imidazol-2-il)-l-metilpiperidin-4-il)-3-(4-cianofenil)-karbamid-maleát kristályformái
US10779980B2 (en)	2016-04-27	2020-09-22	Synerz Medical, Inc.	Intragastric device for treating obesity
JP7792189B2 (ja) *	2019-03-29	2025-12-25	デクセリアルズ株式会社	接着剤組成物
HRP20240302T1 (hr)	2020-01-28	2024-05-10	Assia Chemical Industries Ltd	Postupci za pripremu glasdegiba i njegove soli i krutih oblika glasdegib maleata i postupak za njihovu pripremu
CN113248475B (zh) *	2020-02-11	2023-03-17	中国科学院上海药物研究所	一类杂环取代的苯并咪唑二聚体或其药学上可接受的盐、组合物及其用途
EP4126237B1 (en)	2020-03-26	2024-04-10	LEK Pharmaceuticals d.d.	Dimaleate form of 1-((2r,4r)-2-(1h-benzo[d]imidazol-2-yl)-1-methylpiperidin-4-yl)-3-(4-cyanophenyl)urea
WO2021261601A1 (ja)	2020-06-26	2021-12-30	ラクオリア創薬株式会社	レチノイドとがん治療薬との併用療法が有効ながん患者の選択方法およびレチノイドとがん治療薬との併用医薬
WO2023002362A1 (en)	2021-07-22	2023-01-26	Pfizer Inc.	Treatment of hematological malignancy

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2003011219A2 (en)	2001-07-27	2003-02-13	Curis, Inc.	Mediators of hedgehog signaling pathways, compositions and uses related thereto
DK1499607T3 (da)	2001-12-04	2006-04-18	Actelion Pharmaceuticals Ltd	4-(piperidyl- og pyrrolidyl-alkyl-ureido)-quinoliner som urotensin II-receptorantagonister
TW200304820A (en)	2002-03-25	2003-10-16	Avanir Pharmaceuticals	Use of benzimidazole analogs in the treatment of cell proliferation
US7582761B2 (en)	2002-10-17	2009-09-01	Amgen Inc.	Vanilloid receptor ligands and their use in treatments
WO2005042495A1 (en)	2003-10-21	2005-05-12	Imclone Systems Incorporated	(benzimidazol-2-yl)-phenyl-phenyl-urea compounds and methods for inhibiting heparanase activity
WO2005042497A2 (en)	2003-10-28	2005-05-12	Vertex Pharmaceuticals, Incorporated	Benzimidazoles useful as modulators of ion channels
CA2587489C (en) *	2004-11-03	2013-12-31	Curis, Inc.	Mediators of hedgehog signaling pathways, compositions and uses related thereto
DE102005012875B4 (de)	2005-03-19	2006-11-16	Sanofi-Aventis Deutschland Gmbh	Verwendung von Amino substituierten 8-N-Benzimidazolen
WO2006124780A2 (en) *	2005-05-12	2006-11-23	Kalypsys, Inc.	Ih-benzo [d] imidazole compounds as inhibitors of b-raf kinase
WO2008064830A1 (en)	2006-11-27	2008-06-05	Ucb Pharma, S.A.	Bicyclic and heterobicyclic derivatives, processes for preparing them and their pharmaceutical uses
EP2121626A1 (en)	2006-12-15	2009-11-25	Pfizer Products Inc.	Benzimidazole derivatives
ES2609258T3 (es)	2007-06-29	2017-04-19	Pfizer Inc.	Derivados de bencimidazol
US20120094974A1 (en)	2008-06-17	2012-04-19	Wei Chen	Smoothened receptor modulators
KR101354763B1 (ko)	2008-08-25	2014-01-22	아이알엠 엘엘씨	헷지호그 경로 조절제

2008
- 2008-06-16 ES ES08762901.0T patent/ES2609258T3/es active Active
- 2008-06-16 KR KR1020107001991A patent/KR101143246B1/ko active Active
- 2008-06-16 EA EA200971104A patent/EA016888B1/ru unknown
- 2008-06-16 ME MEP-2009-349A patent/ME00962B/me unknown
- 2008-06-16 PL PL08762901T patent/PL2170860T3/pl unknown
- 2008-06-16 RS RS20161132A patent/RS55395B9/sr unknown
- 2008-06-16 MY MYPI20095266A patent/MY148636A/en unknown
- 2008-06-16 GE GEAP200811622A patent/GEP20125702B/en unknown
- 2008-06-16 SI SI200831707A patent/SI2170860T1/sl unknown
- 2008-06-16 AU AU2008272641A patent/AU2008272641B2/en active Active
- 2008-06-16 WO PCT/IB2008/001575 patent/WO2009004427A2/en not_active Ceased
- 2008-06-16 JP JP2010514162A patent/JP4567099B2/ja active Active
- 2008-06-16 DK DK08762901.0T patent/DK2170860T5/en active
- 2008-06-16 NZ NZ581889A patent/NZ581889A/en unknown
- 2008-06-16 HR HRP20161562TT patent/HRP20161562T2/hr unknown
- 2008-06-16 PT PT87629010T patent/PT2170860T/pt unknown
- 2008-06-16 CA CA2690953A patent/CA2690953C/en active Active
- 2008-06-16 CN CN200880022602XA patent/CN101687841B/zh active Active
- 2008-06-16 AP AP2009005089A patent/AP2377A/xx active
- 2008-06-16 EP EP08762901.0A patent/EP2170860B9/en active Active
- 2008-06-16 LT LTEP08762901.0T patent/LT2170860T/lt unknown
- 2008-06-16 HU HUE08762901A patent/HUE030052T4/en unknown
- 2008-06-16 BR BRPI0813412A patent/BRPI0813412B8/pt active IP Right Grant
- 2008-06-19 US US12/142,119 patent/US8148401B2/en active Active
- 2008-06-19 PA PA20088785401A patent/PA8785401A1/es unknown
- 2008-06-20 UY UY31164A patent/UY31164A1/es active IP Right Grant
- 2008-06-25 HN HN2008000974A patent/HN2008000974A/es unknown
- 2008-06-27 PE PE2012000473A patent/PE20121010A1/es active IP Right Grant
- 2008-06-27 CL CL2008001922A patent/CL2008001922A1/es unknown
- 2008-06-27 TW TW097124392A patent/TWI371451B/zh active
- 2008-06-27 AR ARP080102792A patent/AR067346A1/es active IP Right Grant
- 2008-06-27 PE PE2008001105A patent/PE20090772A1/es active IP Right Grant
2009
- 2009-11-30 IL IL202420A patent/IL202420A/en active IP Right Grant
- 2009-12-07 CR CR11150A patent/CR11150A/es unknown
- 2009-12-08 DO DO2009000278A patent/DOP2009000278A/es unknown
- 2009-12-14 EC EC2009009803A patent/ECSP099803A/es unknown
- 2009-12-18 NI NI200900219A patent/NI200900219A/es unknown
- 2009-12-21 GT GT200900328A patent/GT200900328A/es unknown
- 2009-12-21 CU CU2009000225A patent/CU23847B1/es active IP Right Grant
- 2009-12-23 CO CO09147462A patent/CO6160232A2/es unknown
- 2009-12-25 TN TNP2009000544A patent/TN2009000544A1/fr unknown
- 2009-12-29 MA MA32454A patent/MA31466B1/fr unknown
2010
- 2010-08-04 JP JP2010175465A patent/JP2010280693A/ja active Pending
2012
- 2012-02-24 US US13/404,169 patent/US8431597B2/en active Active
2016
- 2016-12-14 CY CY20161101293T patent/CY1118650T1/el unknown
2020
- 2020-07-15 NL NL301057C patent/NL301057I2/nl unknown
- 2020-08-11 NO NO2020027C patent/NO2020027I1/no unknown
- 2020-08-12 CY CY2020028C patent/CY2020028I2/el unknown
- 2020-08-13 HU HUS2000031C patent/HUS2000031I1/hu unknown
- 2020-08-20 FR FR20C1038C patent/FR20C1038I2/fr active Active
- 2020-08-26 LT LTPA2020528C patent/LTC2170860I2/lt unknown

Also Published As

Publication number	Publication date
HRP20161562T2 (hr)	2017-04-21
FR20C1038I2 (fr)	2021-08-13
GT200900328A (es)	2011-08-29
EA200971104A1 (ru)	2010-06-30
CN101687841B (zh)	2013-07-10
DOP2009000278A (es)	2009-12-31
US20090005416A1 (en)	2009-01-01
BRPI0813412B1 (pt)	2020-01-21
CO6160232A2 (es)	2010-05-20
ECSP099803A (es)	2010-01-29
IL202420A0 (en)	2010-06-30
NL301057I2 (nl)	2020-09-10
TWI371451B (en)	2012-09-01
KR20100028120A (ko)	2010-03-11
TW200911792A (en)	2009-03-16
CN101687841A (zh)	2010-03-31
IL202420A (en)	2014-05-28
AR067346A1 (es)	2009-10-07
EP2170860B1 (en)	2016-11-02
AP2377A (en)	2012-03-07
CU23847B1 (es)	2012-10-15
RS55395B9 (sr)	2020-01-31
MA31466B1 (fr)	2010-06-01
UY31164A1 (es)	2009-01-30
PT2170860T (pt)	2017-01-04
HUE030052T2 (hu)	2017-04-28
MY148636A (en)	2013-05-15
SI2170860T1 (sl)	2017-01-31
US20120157495A1 (en)	2012-06-21
BRPI0813412A2 (pt)	2014-12-30
PE20121010A1 (es)	2012-08-06
EA016888B1 (ru)	2012-08-30
JP4567099B2 (ja)	2010-10-20
CY1118650T1 (el)	2017-07-12
LTPA2020528I1 (lt)	2020-09-25
DK2170860T5 (en)	2017-03-20
DK2170860T3 (en)	2017-01-09
AU2008272641A1 (en)	2009-01-08
PA8785401A1 (es)	2009-01-23
US8148401B2 (en)	2012-04-03
CA2690953C (en)	2012-10-02
CU20090225A7 (es)	2012-02-15
FR20C1038I1 (lt)	2020-10-02
ME00962B (me)	2012-06-20
HK1139658A1 (en)	2010-09-24
CY2020028I1 (el)	2020-11-25
RS55395B1 (sr)	2017-04-28
CR11150A (es)	2010-02-08
NO2020027I1 (no)	2020-08-11
WO2009004427A2 (en)	2009-01-08
CA2690953A1 (en)	2009-01-08
BRPI0813412B8 (pt)	2021-05-25
CL2008001922A1 (es)	2009-01-02
TN2009000544A1 (fr)	2011-03-31
CY2020028I2 (el)	2020-11-25
AP2009005089A0 (en)	2009-12-31
EP2170860B9 (en)	2017-02-22
HUS2000031I1 (hu)	2020-09-28
HRP20161562T1 (hr)	2016-12-30
NZ581889A (en)	2011-05-27
PL2170860T3 (pl)	2017-05-31
ES2609258T3 (es)	2017-04-19
JP2010280693A (ja)	2010-12-16
LT2170860T (lt)	2017-01-10
KR101143246B1 (ko)	2012-05-18
GEP20125702B (en)	2012-12-10
NL301057I1 (nl)	2020-07-22
EP2170860A2 (en)	2010-04-07
NI200900219A (es)	2010-03-11
PE20090772A1 (es)	2009-06-24
US8431597B2 (en)	2013-04-30
AU2008272641B2 (en)	2013-08-29
WO2009004427A3 (en)	2009-06-04
HN2008000974A (es)	2011-01-24
JP2010531869A (ja)	2010-09-30
HUE030052T4 (en)	2017-06-28

Publication	Publication Date	Title
LTC2170860I2 (lt)	2022-03-10	Benzimidazolo dariniai
DK2164844T3 (da)	2012-08-20	Pyrimidinyl-pyridazinonderivater
DK2209786T3 (da)	2013-06-03	Pyrimidinsubstituerede purinderivater
BRPI0813836A2 (pt)	2015-01-06	Derivados pirazólicos
DK2308877T3 (da)	2014-04-22	Imidazopyridin-2-on-derivater
BRPI0820112A2 (pt)	2015-05-05	Derivados de isoxazol-piridina
BRPI0809992A2 (pt)	2014-10-14	Derivados de pirrolopirimidina
BRPI0820113A2 (pt)	2015-05-05	Derivados de isoxazolo-piridazina
ATE518837T1 (de)	2011-08-15	Indazolamidderivate
BRPI0812155A2 (pt)	2019-09-24	derivados de espiroindolinona
BRPI0817935A2 (pt)	2015-04-07	Derivados de biarila
DK2152370T3 (da)	2011-08-15	Aryletherpyridazinonderivater
BRPI0814236A2 (pt)	2015-01-06	Derivados de quinazolinamida
BRPI0820649A2 (pt)	2015-06-16	Derivados de isoxazalo-pirazina
DK2142533T3 (da)	2011-12-12	Imidazolidinonderivater
DK2190837T3 (da)	2012-10-08	4-pyrimidinsulfamid-derivat
DK2275414T3 (da)	2015-06-22	Cyclopentylacrylamidderivat
ATE545635T1 (de)	2012-03-15	Substituierte n-oxidpyrazinderivate
BRPI0821315A2 (pt)	2019-09-24	compostos benzimidazol
ATE519760T1 (de)	2011-08-15	Isoxazolimidazolderivate
ATE534634T1 (de)	2011-12-15	2-phenyl-4-cyclopropyl-pyrimidinderivate
ATE546446T1 (de)	2012-03-15	5-aminocyclylmethyl-oxazolidin-2-eins-derivativ
ATE467626T1 (de)	2010-05-15	Indol-2-yl-piperazin-1-yl-methanon-derivate
BRPI0811214A2 (pt)	2014-10-29	Derivados de pirazolona
DK2167469T3 (da)	2012-11-12	Sulfonylquinolinderivater