LV12308B - COMPOSITIONS CONTAINING ISOTIAZOLIC DERIVATIVES AND BIOACTIC PRODUCED FROM THE BODY - Google Patents

COMPOSITIONS CONTAINING ISOTIAZOLIC DERIVATIVES AND BIOACTIC PRODUCED FROM THE BODY Download PDF

Info

Publication number: LV12308B
Authority: LV; Latvia
Prior art keywords: peat; composition according; compound; bioactive; product
Prior art date: 1991-10-26

Application number

LVP-99-45A

Other languages

English (en)

Latvian (lv)

Other versions

LV12308A (lv

Inventor

Prof. Anna Dubowska Inglot

Original Assignee

Torf Establishment

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-10-26

Filing date

1999-03-18

Publication date

1999-11-20

1991-10-26 Priority claimed from EP91118269A external-priority patent/EP0539610A1/fr

1999-03-18 Application filed by Torf Establishment filed Critical Torf Establishment

1999-07-20 Publication of LV12308A publication Critical patent/LV12308A/xx

1999-11-20 Publication of LV12308B publication Critical patent/LV12308B/en

Links

239000000203 mixture Substances 0.000 title claims abstract description 35
239000003415 peat Substances 0.000 title claims abstract description 27
230000000975 bioactive effect Effects 0.000 title claims abstract description 19
150000003854 isothiazoles Chemical class 0.000 title abstract description 8
239000000284 extract Substances 0.000 claims abstract description 8
150000001875 compounds Chemical class 0.000 claims description 19
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 12
150000003839 salts Chemical class 0.000 claims description 9
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 7
239000000243 solution Substances 0.000 claims description 7
-1 isothiazole compound Chemical class 0.000 claims description 6
239000011780 sodium chloride Substances 0.000 claims description 6
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 5
239000003937 drug carrier Substances 0.000 claims description 4
238000000034 method Methods 0.000 claims description 4
125000003854 p-chlorophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C([H])=C1Cl 0.000 claims description 4
125000000217 alkyl group Chemical group 0.000 claims description 3
125000000068 chlorophenyl group Chemical group 0.000 claims description 3
239000000463 material Substances 0.000 claims description 3
239000007864 aqueous solution Substances 0.000 claims description 2
239000003814 drug Substances 0.000 claims description 2
125000005059 halophenyl group Chemical group 0.000 claims description 2
239000007787 solid Substances 0.000 claims description 2
AZPOILAPQDCYHM-UHFFFAOYSA-N 4-amino-1-chlorocyclohexa-2,4-diene-1-carboxylic acid N-(3-methyl-1,2-thiazol-5-yl)benzamide Chemical compound NC1=CCC(Cl)(C(O)=O)C=C1.S1N=C(C)C=C1NC(=O)C1=CC=CC=C1 AZPOILAPQDCYHM-UHFFFAOYSA-N 0.000 claims 1
KUDPGZONDFORKU-UHFFFAOYSA-N n-chloroaniline Chemical compound ClNC1=CC=CC=C1 KUDPGZONDFORKU-UHFFFAOYSA-N 0.000 claims 1
238000001694 spray drying Methods 0.000 claims 1
238000005507 spraying Methods 0.000 claims 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
239000000825 pharmaceutical preparation Substances 0.000 abstract description 9
230000000840 anti-viral effect Effects 0.000 abstract description 3
239000002260 anti-inflammatory agent Substances 0.000 abstract description 2
229940124599 anti-inflammatory drug Drugs 0.000 abstract description 2
239000003443 antiviral agent Substances 0.000 abstract description 2
ZPBLNADJHWHOEP-UHFFFAOYSA-N 5-benzamido-n-(4-chlorophenyl)-3-methyl-1,2-thiazole-4-carboxamide Chemical compound C=1C=C(Cl)C=CC=1NC(=O)C=1C(C)=NSC=1NC(=O)C1=CC=CC=C1 ZPBLNADJHWHOEP-UHFFFAOYSA-N 0.000 description 8
239000004615 ingredient Substances 0.000 description 6
238000011282 treatment Methods 0.000 description 5
PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 4
102000014150 Interferons Human genes 0.000 description 4
108010050904 Interferons Proteins 0.000 description 4
108060008682 Tumor Necrosis Factor Proteins 0.000 description 4
229940047124 interferons Drugs 0.000 description 4
238000002360 preparation method Methods 0.000 description 4
102000003390 tumor necrosis factor Human genes 0.000 description 4
210000004400 mucous membrane Anatomy 0.000 description 3
102000004127 Cytokines Human genes 0.000 description 2
108090000695 Cytokines Proteins 0.000 description 2
201000004624 Dermatitis Diseases 0.000 description 2
230000000694 effects Effects 0.000 description 2
210000004392 genitalia Anatomy 0.000 description 2
235000011187 glycerol Nutrition 0.000 description 2
CGIGDMFJXJATDK-UHFFFAOYSA-N indomethacin Chemical compound CC1=C(CC(O)=O)C2=CC(OC)=CC=C2N1C(=O)C1=CC=C(Cl)C=C1 CGIGDMFJXJATDK-UHFFFAOYSA-N 0.000 description 2
239000000411 inducer Substances 0.000 description 2
208000015181 infectious disease Diseases 0.000 description 2
238000004519 manufacturing process Methods 0.000 description 2
229940057838 polyethylene glycol 4000 Drugs 0.000 description 2
238000001223 reverse osmosis Methods 0.000 description 2
230000009385 viral infection Effects 0.000 description 2
QSNSCYSYFYORTR-UHFFFAOYSA-N 4-chloroaniline Chemical compound NC1=CC=C(Cl)C=C1 QSNSCYSYFYORTR-UHFFFAOYSA-N 0.000 description 1
QJXTYTDYZIWGCW-UHFFFAOYSA-N 5-amino-1,2-thiazole-4-carboxylic acid Chemical compound NC=1SN=CC=1C(O)=O QJXTYTDYZIWGCW-UHFFFAOYSA-N 0.000 description 1
239000004215 Carbon black (E152) Substances 0.000 description 1
208000031886 HIV Infections Diseases 0.000 description 1
241000200696 Halictus simplex Species 0.000 description 1
241001560589 Hemitaurichthys zoster Species 0.000 description 1
208000029433 Herpesviridae infectious disease Diseases 0.000 description 1
DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 1
239000002253 acid Substances 0.000 description 1
239000004480 active ingredient Substances 0.000 description 1
150000001408 amides Chemical class 0.000 description 1
230000000844 anti-bacterial effect Effects 0.000 description 1
230000001857 anti-mycotic effect Effects 0.000 description 1
208000010668 atopic eczema Diseases 0.000 description 1
230000015572 biosynthetic process Effects 0.000 description 1
239000001768 carboxy methyl cellulose Substances 0.000 description 1
238000007796 conventional method Methods 0.000 description 1
239000002537 cosmetic Substances 0.000 description 1
238000000605 extraction Methods 0.000 description 1
229960005150 glycerol Drugs 0.000 description 1
229930195733 hydrocarbon Natural products 0.000 description 1
150000002430 hydrocarbons Chemical class 0.000 description 1
229960000905 indomethacin Drugs 0.000 description 1
210000000265 leukocyte Anatomy 0.000 description 1
238000002156 mixing Methods 0.000 description 1
229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 description 1
229940067003 orabase Drugs 0.000 description 1
239000001814 pectin Substances 0.000 description 1
235000010987 pectin Nutrition 0.000 description 1
229920001277 pectin Polymers 0.000 description 1
210000005259 peripheral blood Anatomy 0.000 description 1
239000011886 peripheral blood Substances 0.000 description 1
229940068886 polyethylene glycol 300 Drugs 0.000 description 1
235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 1
229920000136 polysorbate Polymers 0.000 description 1
229920000053 polysorbate 80 Polymers 0.000 description 1
230000003389 potentiating effect Effects 0.000 description 1
230000002265 prevention Effects 0.000 description 1
238000011321 prophylaxis Methods 0.000 description 1
230000001568 sexual effect Effects 0.000 description 1
206010040872 skin infection Diseases 0.000 description 1
235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
239000000126 substance Substances 0.000 description 1
125000001424 substituent group Chemical group 0.000 description 1
230000002195 synergetic effect Effects 0.000 description 1
238000003786 synthesis reaction Methods 0.000 description 1
230000001225 therapeutic effect Effects 0.000 description 1
150000007979 thiazole derivatives Chemical class 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
- A61K35/10—Peat; Amber; Turf; Humus

Landscapes

Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Medicinal Preparation (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Thiazole And Isothizaole Compounds (AREA)

LVP-99-45A 1991-10-26 1999-03-18 COMPOSITIONS CONTAINING ISOTIAZOLIC DERIVATIVES AND BIOACTIC PRODUCED FROM THE BODY LV12308B (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP91118269A EP0539610A1 (fr)	1991-10-26	1991-10-26	Méthode et composition pour déterminer l'activité immunlogique de solutions contenant substances actifs
EP92116552		1992-09-28

Publications (2)

Publication Number	Publication Date
LV12308A LV12308A (lv)	1999-07-20
LV12308B true LV12308B (en)	1999-11-20

Family

ID=26129062

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
LVP-99-45A LV12308B (en)	1991-10-26	1999-03-18	COMPOSITIONS CONTAINING ISOTIAZOLIC DERIVATIVES AND BIOACTIC PRODUCED FROM THE BODY

Country Status (8)

Country	Link
EP (1)	EP0540945B1 (fr)
AT (1)	ATE164072T1 (fr)
DE (2)	DE69224789T2 (fr)
DK (1)	DK0540945T3 (fr)
ES (1)	ES2059292T3 (fr)
GR (1)	GR930300101T1 (fr)
LV (1)	LV12308B (fr)
SG (1)	SG47617A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6267962B1 (en)	1990-12-21	2001-07-31	C-P Technology Limited Partnership	Compositions and methods of treatment using peat derivatives
AU7877894A (en) *	1993-09-24	1995-04-10	Maurizio Zanetti	Treatment of hiv infection with humic acid

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE533865T1 (de) *	1991-03-16	1993-11-04	Torf Establishment, Vaduz	Torf-derivierte bioaktive produkte und diese enthaltende pharmazeutische und kosmetische zusammensetzungen.

1992
- 1992-10-22 AT AT92118053T patent/ATE164072T1/de not_active IP Right Cessation
- 1992-10-22 ES ES92118053T patent/ES2059292T3/es not_active Expired - Lifetime
- 1992-10-22 DE DE69224789T patent/DE69224789T2/de not_active Expired - Fee Related
- 1992-10-22 EP EP92118053A patent/EP0540945B1/fr not_active Expired - Lifetime
- 1992-10-22 DK DK92118053T patent/DK0540945T3/da active
- 1992-10-22 SG SG1996002318A patent/SG47617A1/en unknown
- 1992-10-22 DE DE92118053T patent/DE540945T1/de active Pending
1993
- 1993-10-29 GR GR930300101T patent/GR930300101T1/el unknown
1999
- 1999-03-18 LV LVP-99-45A patent/LV12308B/en unknown

Also Published As

Publication number	Publication date
HK1004059A1 (en)	1998-11-13
EP0540945B1 (fr)	1998-03-18
SG47617A1 (en)	1998-04-17
ES2059292T1 (es)	1994-11-16
DE69224789T2 (de)	1998-08-20
GR930300101T1 (en)	1993-10-29
DE540945T1 (de)	1993-12-16
DE69224789D1 (de)	1998-04-23
ES2059292T3 (es)	1998-06-16
LV12308A (lv)	1999-07-20
EP0540945A1 (fr)	1993-05-12
DK0540945T3 (da)	1998-12-28
ATE164072T1 (de)	1998-04-15

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CA1218608A (fr)	1987-03-03	Acide undecylenique pour le traitement de l'herpes labial
ES8308833A1 (es)	1983-10-01	"un metodo para la preparacion de 3-fenil-1-indanaminas".
KR960015953B1 (ko)	1996-11-25	피부에 축적하는 외용의 항바이러스성 약학적 조성물 및 그 제조방법
JPS5877824A (ja)	1983-05-11	インターフェロンを含む組成物
HK1004059B (en)	1998-11-13	Compositions comprising an isothiazole derivative and a peat-derived bioactive product
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JPH02256609A (ja)	1990-10-17	化粧品用添加剤およびそれを含有する化粧品
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JPS624366B2 (fr)	1987-01-30