MA24340A1 - Procede de production de derives nouveaux d'aminophosphates, et de compositions pharmaceutiques les contenant - Google Patents

Procede de production de derives nouveaux d'aminophosphates, et de compositions pharmaceutiques les contenant

Info

Publication number: MA24340A1
Authority: MA; Morocco
Prior art keywords: aminophosphates; pharmaceutical compositions; compositions containing; novel derivatives; producing novel
Prior art date: 1995-06-30

Application number

MA24297A

Other languages

English (en)

Inventor

Azoulay Raymond

Floret Simon

Van Diep Vinh

Leigh Bentzen Craig

Niesor Eric

John Ife Robert

Bulla Alexandre

Guyon-Gellin Yves

Trung Phan Hieu

Mong Nguyen Lang

Original Assignee

Symphar Sa

Smithkline Beecham Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-06-30

Filing date

1996-06-28

Publication date

1998-07-01

1996-06-28 Application filed by Symphar Sa, Smithkline Beecham Plc filed Critical Symphar Sa

1998-07-01 Publication of MA24340A1 publication Critical patent/MA24340A1/fr

Links

239000008194 pharmaceutical composition Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4056—Esters of arylalkanephosphonic acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/58—Pyridine rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/59—Hydrogenated pyridine rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65586—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Diabetes (AREA)
Hematology (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Obesity (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

MA24297A 1995-06-30 1996-06-28 Procede de production de derives nouveaux d'aminophosphates, et de compositions pharmaceutiques les contenant MA24340A1 (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH01920/95A CH690264A5 (fr)	1995-06-30	1995-06-30	Dérivés aminophosphonates substitués, leur procédé de préparation et leur utilisation pour la préparation de compositions pharmaceutiques.

Publications (1)

Publication Number	Publication Date
MA24340A1 true MA24340A1 (fr)	1998-07-01

Family

ID=4221681

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MA24297A MA24340A1 (fr)	1995-06-30	1996-06-28	Procede de production de derives nouveaux d'aminophosphates, et de compositions pharmaceutiques les contenant

Country Status (27)

Country	Link
US (2)	US6060464A (fr)
EP (1)	EP0835116A1 (fr)
JP (1)	JPH11508576A (fr)
KR (1)	KR19990028542A (fr)
CN (1)	CN1113654C (fr)
AP (1)	AP778A (fr)
AR (1)	AR004498A1 (fr)
AU (1)	AU705206B2 (fr)
BG (1)	BG102215A (fr)
BR (1)	BR9609653A (fr)
CA (1)	CA2225391A1 (fr)
CH (1)	CH690264A5 (fr)
CZ (1)	CZ422097A3 (fr)
EA (1)	EA199800106A1 (fr)
HU (1)	HUP9901684A3 (fr)
IL (1)	IL122717A0 (fr)
MA (1)	MA24340A1 (fr)
MX (1)	MX9800189A (fr)
NO (1)	NO976128L (fr)
NZ (1)	NZ312696A (fr)
OA (1)	OA10554A (fr)
PL (1)	PL187024B1 (fr)
SK (1)	SK178397A3 (fr)
TR (1)	TR199701700T1 (fr)
TW (1)	TW413681B (fr)
WO (1)	WO1997002037A1 (fr)
ZA (1)	ZA965505B (fr)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6548084B2 (en)	1995-07-20	2003-04-15	Smithkline Beecham Plc	Controlled release compositions
GB9626615D0 (en)	1996-12-20	1997-02-05	Symphar Sa	Novel compounds
GB9626616D0 (en) *	1996-12-20	1997-02-05	Symphar Sa	Novel compounds
GB9626536D0 (en) *	1996-12-20	1997-02-05	Symphar Sa	Novel compounds
DE19748659A1 (de) *	1997-11-04	1999-05-06	Hoechst Ag	Aminophosphoniumgruppen enthaltende vernetzte Copolymere für medizinische Verwendungen
US6017918A (en) *	1998-08-06	2000-01-25	Warner-Lambert Company	Phenyl glycine compounds and methods of treating atherosclerosis and restenosis
US6284795B1 (en)	1998-09-04	2001-09-04	Warner-Lambert Company	Sulfonamide compounds and methods of treating atherosclerosis and restenosis
WO2001030339A1 (fr)	1999-10-27	2001-05-03	Teva Pharmaceutical Industries, Ltd.	Utilisation de derives de 1-aminoindan pour le traitement de la manie liée à la psychose maniacodépressive
SI1686119T1 (sl)	2000-02-16	2009-12-31	Smithkline Beecham Plc	Derivati pirimidin-5-ona kot inhibitorji ldl-pla2
JP2004513891A (ja) *	2000-09-27	2004-05-13	アイレックス　オンコロジー　リサーチ　エス．エイ．	α−置換β−アミノエチルホスホネート
US20030114421A1 (en) *	2000-09-27	2003-06-19	Phan Hieu Trung	Alpha-substituted beta-aminoethyl phosphonate derivatives
GB0024808D0 (en)	2000-10-10	2000-11-22	Smithkline Beecham Plc	Novel compounds
GB0025849D0 (en) *	2000-10-23	2000-12-06	Smithkline Beecham Plc	Novel compounds
AU2003219701A1 (en) *	2002-02-11	2003-09-04	Ilex Products, Inc.	Alpha-substituted heteroarylalkyl phosphonate derivatives
AU2003228990A1 (en) *	2002-05-11	2003-11-11	Ilex Products, Inc.	Hydroxyphosphonates and phosphonophosphates as apolipoprotein e modulators
MXPA05002331A (es) *	2002-08-30	2005-08-18	Biostratum Inc	Inhibidores de productos terminales de glicacion avanzada post-amadori.
JP5886310B2 (ja)	2010-12-06	2016-03-16	グラクソグループリミテッドＧｌａｘｏＧｒｏｕｐＬｉｍｉｔｅｄ	Ｌｐ−ＰＬＡ２により媒介される疾患または状態の処置における使用のためのピリミジノン化合物
JP2014521625A (ja)	2011-07-27	2014-08-28	グラクソグループリミテッド	二環式ピリミドン化合物
CA2842965A1 (fr)	2011-07-27	2013-01-31	Glaxo Group Limited	Composes 2,3-dihydroimidazo[1,2-c]pyrimidin-5(1h)-one et utilisation en tant qu'inhibiteurs de lp-pla2
EA027972B1 (ru)	2011-09-01	2017-09-29	Глэксо Груп Лимитед	Новая кристаллическая форма
KR20150111356A (ko)	2013-01-25	2015-10-05	글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드	화합물
BR112015017397A2 (pt)	2013-01-25	2017-07-11	Glaxosmithkline Ip Dev Ltd	compostos pirimidona bicíclica como inibidores de lp-pla2
JP6306053B2 (ja)	2013-01-25	2018-04-04	グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅＩｎｔｅｌｌｅｃｔｕａｌＰｒｏｐｅｒｔｙＤｅｖｅｌｏｐｍｅｎｔＬｉｍｉｔｅｄ	２，３−ジヒドロイミダゾール［１，２−ｃ］ピリミジン−５（１Ｈ）−オンに基づくリポタンパク質関連ホスホリパーゼＡ２（Ｌｐ−ＰＬＡ２）阻害剤
WO2016012916A1 (fr)	2014-07-22	2016-01-28	Glaxosmithkline Intellectual Property Development Limited	Dérivés 1,2,3,5-tétrahydro-imidazo [1,2-c]pyrimidine utiles pour le traitement de maladies et de troubles médiés par la lp-pla2
WO2016012917A1 (fr)	2014-07-22	2016-01-28	Glaxosmithkline Intellectual Property Development Limited	Dérivés 1,2,3,5-tétrahydro-imidazo [1,2-c]pyrimidine utiles pour le traitement de maladies et de troubles médiés par la lp-pla2
EP4056571A4 (fr)	2019-11-09	2024-01-24	Shanghai Simr Biotechnology Co., Ltd.	Dérivé de dihydroimidazopyrimidone tricyclique, son procédé de préparation, composition pharmaceutique et son utilisation
CN115304620A (zh)	2021-05-07	2022-11-08	上海赛默罗生物科技有限公司	嘧啶酮衍生物、其制备方法、药物组合物和用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH683996A5 (fr) *	1992-03-05	1994-06-30	Symphar Sa	Dérivés aminophosphonates substitués, leur procédé de préparation et compositions pharmaceutiques les contenant.
DE4433244A1 (de) *	1994-09-19	1996-03-28	Hoechst Ag	Aminomethylphosphon- und Aminomethylphosphinsäure-Derivate und deren Verwendung zur Behandlung von degenerativen Gelenkserkrankungen

1995
- 1995-06-30 CH CH01920/95A patent/CH690264A5/fr not_active IP Right Cessation
1996
- 1996-06-26 CZ CZ974220A patent/CZ422097A3/cs unknown
- 1996-06-26 HU HU9901684A patent/HUP9901684A3/hu unknown
- 1996-06-26 CN CN96196395A patent/CN1113654C/zh not_active Expired - Fee Related
- 1996-06-26 US US08/973,669 patent/US6060464A/en not_active Expired - Fee Related
- 1996-06-26 TR TR97/01700T patent/TR199701700T1/xx unknown
- 1996-06-26 EP EP96923971A patent/EP0835116A1/fr not_active Withdrawn
- 1996-06-26 EA EA199800106A patent/EA199800106A1/ru unknown
- 1996-06-26 AP APAP/P/1997/001160A patent/AP778A/en active
- 1996-06-26 IL IL12271796A patent/IL122717A0/xx unknown
- 1996-06-26 WO PCT/EP1996/002842 patent/WO1997002037A1/fr not_active Ceased
- 1996-06-26 CA CA002225391A patent/CA2225391A1/fr not_active Abandoned
- 1996-06-26 NZ NZ312696A patent/NZ312696A/en unknown
- 1996-06-26 JP JP9504801A patent/JPH11508576A/ja not_active Withdrawn
- 1996-06-26 KR KR1019970709860A patent/KR19990028542A/ko not_active Withdrawn
- 1996-06-26 SK SK1783-97A patent/SK178397A3/sk unknown
- 1996-06-26 BR BR9609653-5A patent/BR9609653A/pt not_active Application Discontinuation
- 1996-06-26 MX MX9800189A patent/MX9800189A/es unknown
- 1996-06-26 AU AU64185/96A patent/AU705206B2/en not_active Ceased
- 1996-06-26 PL PL96324341A patent/PL187024B1/pl unknown
- 1996-06-28 AR ARP960103399A patent/AR004498A1/es unknown
- 1996-06-28 ZA ZA9605505A patent/ZA965505B/xx unknown
- 1996-06-28 MA MA24297A patent/MA24340A1/fr unknown
- 1996-07-01 TW TW085107922A patent/TW413681B/zh not_active IP Right Cessation
1997
- 1997-12-29 NO NO976128A patent/NO976128L/no not_active Application Discontinuation
- 1997-12-30 OA OA70171A patent/OA10554A/en unknown
1998
- 1998-01-28 BG BG102215A patent/BG102215A/xx unknown
2000
- 2000-04-03 US US09/541,217 patent/US6660724B1/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
AR004498A1 (es)	1998-12-16
AP778A (en)	1999-10-29
EP0835116A1 (fr)	1998-04-15
SK178397A3 (en)	1998-06-03
TW413681B (en)	2000-12-01
TR199701700T1 (xx)	1998-03-21
CH690264A5 (fr)	2000-06-30
MX9800189A (es)	1998-04-30
AU705206B2 (en)	1999-05-20
HUP9901684A2 (hu)	1999-09-28
NO976128L (no)	1998-02-10
AP9701160A0 (en)	1998-01-31
CN1113654C (zh)	2003-07-09
JPH11508576A (ja)	1999-07-27
US6660724B1 (en)	2003-12-09
AU6418596A (en)	1997-02-05
BG102215A (en)	1998-09-30
NO976128D0 (no)	1997-12-29
US6060464A (en)	2000-05-09
ZA965505B (en)	1998-03-30
HUP9901684A3 (en)	2000-04-28
IL122717A0 (en)	1998-08-16
WO1997002037A1 (fr)	1997-01-23
BR9609653A (pt)	1999-12-21
KR19990028542A (ko)	1999-04-15
EA199800106A1 (ru)	1998-08-27
CA2225391A1 (fr)	1997-01-23
OA10554A (en)	2002-05-29
PL187024B1 (pl)	2004-04-30
NZ312696A (en)	1999-10-28
CZ422097A3 (cs)	1998-10-14
PL324341A1 (en)	1998-05-25
CN1193913A (zh)	1998-09-23

Publication	Publication Date	Title
MA24340A1 (fr)	1998-07-01	Procede de production de derives nouveaux d'aminophosphates, et de compositions pharmaceutiques les contenant
FR2742148B1 (fr)	1999-10-22	Nouveaux derives du pyrazole-3-carboxamide, procede pour leur preparation et compositions pharmaceutiques les contenant
FR2740136B1 (fr)	1998-01-09	Derives d'indolin-2-one, procede pour leur preparation et les compositions pharmaceutiques les contenant
MA26675A1 (fr)	2004-12-20	Derives d'acide hydroxypipecolate-hydroxamique nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant
MA26439A1 (fr)	2004-12-20	Derives d'indazole nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant
MA26686A1 (fr)	2004-12-20	Derives de 4,4-biarylpiperidine nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant
MA26638A1 (fr)	2004-12-20	Derives d'isothiazole nouveaux, procede pour leur preparation et compoositions pharmaceutiques les contenant
FR2665898B1 (fr)	1994-03-11	Derives d'amido-3 pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant.
PT78340A (fr)	1984-04-01	Procede de preparation de nouveaux derives de la tetrahydroxy- 3',4',5,7-flavone et des compositions pharmaceutiques les contenant
MA26620A1 (fr)	2004-12-20	Derives bicycliques d'acide hydroxamique nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant
MA23632A1 (fr)	1996-04-01	Procede de preparation de composes nouveaux et de compostions pharmaceutiques les contenant
MA26471A1 (fr)	2004-12-20	Derives d'acide arylsulfonylaminohydroxamique, procede pour leur preparation et compositions pharmaceutiques les contenant.
MA23753A1 (fr)	1996-07-01	Procede de preparation de derives de piperidine nouveaux et de compositions pharmaceutiques contenant ces composes
DZ1923A1 (fr)	2002-02-17	Sels d'un derivé d'indole anti-migraineux, son Procédé de production et composition pharmaceutique le contenant.
FR2735777B1 (fr)	1997-09-12	Derives de 4-phenylaminothiazole, leur procede de preparation et les compositions pharmaceutiques les contenant
MA24469A1 (fr)	1998-10-01	Derives d'acide arylsulfonyhydroxamique, procede pour leur preparation et compositions les contenant
MA26414A1 (fr)	2004-12-20	Derives de quinoleine et de quinazoline nouveaux, procede pour leur preparation et formulations pharmaceutiques les contenant.
MA26571A1 (fr)	2004-12-20	Derives d'acide hydroxamique, compositions pharmaceutiques les contenant et procede pour leur preparation
FR2729951B1 (fr)	1997-04-18	Nouveaux composes heterocycliques, procede pour leur preparation et compositions pharmaceutiques en contenant
FR2738571B1 (fr)	1997-10-17	Nouveaux derives de la 5-0-desosaminyl 6-0-methyl- erythronolide a, leur procede de preparation et leur application a la preparation de produits biologiquement actifs
MA26588A1 (fr)	2004-12-20	Derives d'erythromycine nouveaux, procede et intermediaires pour leur preparation, et compositions pharmaceutiques les contenant
MA23832A1 (fr)	1996-10-01	Derives d'acide hydroxamique nouveaux, procede pour leur production et compositions les contenant
PT83896A (fr)	1987-01-01	Procede pour la preparation de nouveaux conjuges de la vinblas-tine et de ses derives et de compositions pharmaceutiques les contenant
FR2738245B1 (fr)	1997-11-21	Nouveaux derives de piperidine, procede pour leur obtention et compositions pharmaceutiques les contenant
MA26603A1 (fr)	2004-12-20	Derives d'acide dihydroxyhexanoique nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant