MA27329A1 - Promedicaments a nucleosides 2' et 3' destines a traiter les infections aux flavivirus - Google Patents

Promedicaments a nucleosides 2' et 3' destines a traiter les infections aux flavivirus

Info

Publication number
MA27329A1
MA27329A1 MA28069A MA28069A MA27329A1 MA 27329 A1 MA27329 A1 MA 27329A1 MA 28069 A MA28069 A MA 28069A MA 28069 A MA28069 A MA 28069A MA 27329 A1 MA27329 A1 MA 27329A1
Authority
MA
Morocco
Prior art keywords
prodrugs
treatment
infections
derivatives
flavivirus infections
Prior art date
Application number
MA28069A
Other languages
English (en)
Inventor
Jean-Pierre Sommadossi
Colla Paolo La
Richard Storer
Gilles Gosselin
Original Assignee
Idenix Cayman Ltd
Univ Cagliari
Centre Nat Rech Scient
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Idenix Cayman Ltd, Univ Cagliari, Centre Nat Rech Scient filed Critical Idenix Cayman Ltd
Publication of MA27329A1 publication Critical patent/MA27329A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

On décrit des 2'- et/ou 3'-promédicaments de nucléosides 1', 2', 3' ou 4'-ramifiés, ainsi que leurs sels et dérivés acceptables en pharmacie. Ces promédicaments sont utiles dans la prévention et le traitement d'infections par des Flaviviridae, y compris une infection par le HCV et d'autres maladies similaires. On décrit des composés et compositions des promédicaments de la présente invention. On met aussi à disposition des procédés et utilisations qui comprennent l'administration d'une quantité efficace des promédicaments de la présente invention, ou de leurs sels ou dérivés acceptables en pharmacie. Ces médicaments peuvent éventuellement être administrés en combinaison ou en alternance avec d'autres agents antiviraux pour prévenir ou traiter des infections par un virus des Flaviviridae et d'autres maladies similaires.
MA28069A 2002-06-28 2005-01-25 Promedicaments a nucleosides 2' et 3' destines a traiter les infections aux flavivirus MA27329A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US39235002P 2002-06-28 2002-06-28
US39235102P 2002-06-28 2002-06-28
US46619403P 2003-04-28 2003-04-28
US47094903P 2003-05-14 2003-05-14
PCT/IB2003/003901 WO2004003000A2 (fr) 2002-06-28 2003-06-27 Promedicaments 2' et 3' de nucleoside permettant de traiter des infections par les flaviviridae

Publications (1)

Publication Number Publication Date
MA27329A1 true MA27329A1 (fr) 2005-05-02

Family

ID=38337686

Family Applications (1)

Application Number Title Priority Date Filing Date
MA28069A MA27329A1 (fr) 2002-06-28 2005-01-25 Promedicaments a nucleosides 2' et 3' destines a traiter les infections aux flavivirus

Country Status (13)

Country Link
EP (1) EP1525209B1 (fr)
JP (1) JP5087211B2 (fr)
KR (1) KR20050055630A (fr)
AP (1) AP2005003211A0 (fr)
AU (1) AU2003263412A1 (fr)
CA (1) CA2490200C (fr)
IL (1) IL165891A0 (fr)
MA (1) MA27329A1 (fr)
MX (1) MXPA04012779A (fr)
NO (1) NO20050466L (fr)
PL (1) PL374792A1 (fr)
RS (1) RS114104A (fr)
WO (1) WO2004003000A2 (fr)

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JP2005537242A (ja) 2005-12-08
CA2490200A1 (fr) 2004-01-08
RS114104A (sr) 2007-02-05
EP1525209B1 (fr) 2017-11-15
MXPA04012779A (es) 2005-08-19
AU2003263412A1 (en) 2004-01-19
KR20050055630A (ko) 2005-06-13
WO2004003000A3 (fr) 2004-11-04
NO20050466L (no) 2005-03-23
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WO2004003000A2 (fr) 2004-01-08

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