MA29966B1 - Traitement des tumeurs neuroendocrines - Google Patents
Traitement des tumeurs neuroendocrinesInfo
- Publication number
- MA29966B1 MA29966B1 MA30950A MA30950A MA29966B1 MA 29966 B1 MA29966 B1 MA 29966B1 MA 30950 A MA30950 A MA 30950A MA 30950 A MA30950 A MA 30950A MA 29966 B1 MA29966 B1 MA 29966B1
- Authority
- MA
- Morocco
- Prior art keywords
- treatment
- neuroendocrine tumors
- tumors
- administration
- possibly
- Prior art date
Links
- 201000011519 neuroendocrine tumor Diseases 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 230000002124 endocrine Effects 0.000 abstract 1
- 229940124302 mTOR inhibitor Drugs 0.000 abstract 1
- 239000003628 mammalian target of rapamycin inhibitor Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/31—Somatostatins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
LA PRÉSENTE INVENTION CONCERNE UN PROCÉDÉ DE TRAITEMENT DES TUMEURS ENDOCRINES, QUI COMPREND L'ADMINISTRATION D'UN INHIBITEUR DE MTOR, ÉVENTUELLEMENT EN ASSOCIATION AVEC UN AUTRE MÉDICAMENT.
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0523658A GB0523658D0 (en) | 2005-11-21 | 2005-11-21 | Organic compounds |
| GB0601082A GB0601082D0 (en) | 2006-01-19 | 2006-01-19 | Organic Compounds |
| GB0602747A GB0602747D0 (en) | 2006-02-10 | 2006-02-10 | Organic compounds |
| GB0607942A GB0607942D0 (en) | 2006-04-21 | 2006-04-21 | Organic compounds |
| GB0609272A GB0609272D0 (en) | 2006-05-10 | 2006-05-10 | Organic compounds |
| GB0609912A GB0609912D0 (en) | 2006-05-18 | 2006-05-18 | Organic compounds |
| EP06120660 | 2006-09-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA29966B1 true MA29966B1 (fr) | 2008-11-03 |
Family
ID=37671355
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA30950A MA29966B1 (fr) | 2005-11-21 | 2008-05-20 | Traitement des tumeurs neuroendocrines |
Country Status (21)
| Country | Link |
|---|---|
| US (3) | US9006224B2 (fr) |
| EP (3) | EP2275103B1 (fr) |
| JP (3) | JP2009516671A (fr) |
| KR (2) | KR20140012218A (fr) |
| CN (1) | CN103446138A (fr) |
| AU (2) | AU2006314444C1 (fr) |
| BR (1) | BRPI0618808A2 (fr) |
| CA (2) | CA2933875C (fr) |
| CY (1) | CY1115299T1 (fr) |
| DK (1) | DK2275103T3 (fr) |
| ES (1) | ES2481671T3 (fr) |
| HR (1) | HRP20140708T1 (fr) |
| IL (3) | IL191475A (fr) |
| MA (1) | MA29966B1 (fr) |
| NO (4) | NO346575B1 (fr) |
| NZ (1) | NZ568182A (fr) |
| PL (1) | PL2275103T3 (fr) |
| PT (1) | PT2275103E (fr) |
| RU (1) | RU2487711C2 (fr) |
| SI (1) | SI2275103T1 (fr) |
| WO (1) | WO2007057457A2 (fr) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LT2762140T (lt) | 2001-02-19 | 2017-06-26 | Novartis Ag | Solidinių smegenų navikų gydymas rapamicino dariniu |
| CN102861338A (zh) * | 2006-04-05 | 2013-01-09 | 诺瓦提斯公司 | 用于治疗癌症、包含bcr-abl/c-kit/pdgf-r tk抑制剂的组合 |
| JP2009532503A (ja) | 2006-04-05 | 2009-09-10 | ノバルティス アクチエンゲゼルシャフト | 癌を処置するための治療剤の組合せ |
| AU2013205002B2 (en) * | 2008-03-21 | 2016-09-15 | The University Of Chicago | Treatment with opioid antagonists and mTOR inhibitors |
| EP2278966B1 (fr) | 2008-03-21 | 2019-10-09 | The University of Chicago | Traitement avec des antagonistes des opioïdes et des inhibiteurs mtor |
| ES3058497T3 (en) | 2008-09-17 | 2026-03-11 | Amryt Endo Inc | Pharmaceutical compositions comprising polypeptides and related methods of delivery |
| WO2010151517A2 (fr) | 2009-06-25 | 2010-12-29 | The Regents Of The University Of Michigan | Lymphocytes t mémoire spécifiques d'un antigène |
| EP3354652B1 (fr) | 2010-03-10 | 2020-05-06 | Incyte Holdings Corporation | Dérivés de pipéridine-4-yl azétidine utilisés en tant qu'inhibiteurs de jak1 |
| KR101978537B1 (ko) * | 2011-10-19 | 2019-05-14 | 시그날 파마소티칼 엘엘씨 | Tor 키나제 억제제를 사용한 암의 치료 |
| JP2016516671A (ja) * | 2013-02-28 | 2016-06-09 | シグナル ファーマシューティカルズ,エルエルシー | Torキナーゼ阻害剤を用いたがんの治療 |
| WO2014144405A1 (fr) * | 2013-03-15 | 2014-09-18 | The Board Of Regents Of The University Of Texas System | Utilisation d'inhibiteurs de mtor pour la prévention du développement et de la croissance d'une tumeur neuroendocrine |
| HK1223286A1 (zh) | 2013-05-29 | 2017-07-28 | 西格诺药品有限公司 | 7-(6-(2-羟基丙-2-基)吡啶-3-基)-1-((反式)-4-甲氧基环己基)-3,4-二氢吡嗪并[2,3-b]吡嗪-2(1h)-酮的药物组合物、其固体形式及它们的使用方法 |
| AU2014373683B2 (en) | 2013-12-31 | 2020-05-07 | Rapamycin Holdings, Llc | Oral rapamycin nanoparticle preparations and use |
| PL3253401T3 (pl) | 2015-02-03 | 2025-08-04 | Amryt Endo, Inc. | Leczenie akromegalii oktreotydem doustnym |
| WO2017000085A1 (fr) * | 2015-06-30 | 2017-01-05 | 上海交通大学 | Utilisation de sunlidac dans la préparation d'un produit de lutte contre le cancer du poumon |
| IL311974A (en) * | 2016-01-21 | 2024-06-01 | Amryt Endo Inc | Somatostatin receptor ligands such as octreotide for oral administration to treat the disease |
| WO2018204477A1 (fr) * | 2017-05-02 | 2018-11-08 | Cornell University | Procédés et réactifs pour ciblage de tumeur avec une efficacité améliorée et une toxicité réduite |
| ES2959860T3 (es) | 2017-06-22 | 2024-02-28 | Celgene Corp | Tratamiento del carcinoma hepatocelular caracterizado por la infección por el virus de la hepatitis B |
| US20210024542A1 (en) * | 2018-02-09 | 2021-01-28 | Torcept Therapeutics, Inc. | Rapamycin analog for prevention and/or treatment of cancer |
| CN118978535A (zh) | 2018-05-01 | 2024-11-19 | 锐新医药公司 | 作为mTOR抑制剂的C40-、C28-及C-32连接的雷帕霉素类似物 |
| CA3098698A1 (fr) | 2018-05-01 | 2019-11-07 | Revolution Medicines, Inc. | Analogues de rapamycine lies a c26 utilises en tant qu'inhibiteurs de mtor |
| WO2020041329A1 (fr) * | 2018-08-20 | 2020-02-27 | Yale University | Polythérapie pour le traitement ou la prévention de la dépression ou d'autres maladies de l'humeur |
| WO2020191002A1 (fr) * | 2019-03-18 | 2020-09-24 | The Regents Of The University Of California | Compositions et procédés pour le traitement d'une maladie de cushing |
| US11141457B1 (en) | 2020-12-28 | 2021-10-12 | Amryt Endo, Inc. | Oral octreotide therapy and contraceptive methods |
| CA3220332A1 (fr) * | 2021-06-07 | 2022-12-15 | Nanopharmaceuticals Llc | Composition et methode de double ciblage dans le traitement de tumeurs neuroendocrines |
| US11723888B2 (en) | 2021-12-09 | 2023-08-15 | Nanopharmaceuticals Llc | Polymer conjugated thyrointegrin antagonists |
| EP4525836A4 (fr) | 2022-05-18 | 2026-02-25 | Hadasit Medical Res Services&Development Ltd | Combinaison d'endocannabinoïdes et d'inhibiteurs de mtor dans le traitement de néoplasmes neuroendocriniens |
| JP2025522296A (ja) | 2022-05-25 | 2025-07-15 | レヴォリューション・メディスンズ,インコーポレイテッド | mTOR阻害剤によりがんを処置する方法 |
Family Cites Families (70)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE28864T1 (de) | 1982-07-23 | 1987-08-15 | Ici Plc | Amide-derivate. |
| GB8327256D0 (en) | 1983-10-12 | 1983-11-16 | Ici Plc | Steroid derivatives |
| IL86632A0 (en) | 1987-06-15 | 1988-11-30 | Ciba Geigy Ag | Derivatives substituted at methyl-amino nitrogen |
| US5538739A (en) * | 1989-07-07 | 1996-07-23 | Sandoz Ltd. | Sustained release formulations of water soluble peptides |
| US5010099A (en) | 1989-08-11 | 1991-04-23 | Harbor Branch Oceanographic Institution, Inc. | Discodermolide compounds, compositions containing same and method of preparation and use |
| GB9013448D0 (en) | 1990-06-15 | 1990-08-08 | Sandoz Ltd | Pharmaceutical resorption-improved somatostatin compositions,their preparation and use |
| PT98990A (pt) | 1990-09-19 | 1992-08-31 | American Home Prod | Processo para a preparacao de esteres de acidos carboxilicos de rapamicina |
| NZ243082A (en) | 1991-06-28 | 1995-02-24 | Ici Plc | 4-anilino-quinazoline derivatives; pharmaceutical compositions, preparatory processes, and use thereof |
| GB9300059D0 (en) | 1992-01-20 | 1993-03-03 | Zeneca Ltd | Quinazoline derivatives |
| TW225528B (fr) | 1992-04-03 | 1994-06-21 | Ciba Geigy Ag | |
| ZA935112B (en) | 1992-07-17 | 1994-02-08 | Smithkline Beecham Corp | Rapamycin derivatives |
| US5234140A (en) | 1992-07-28 | 1993-08-10 | S. C. Johnson & Son, Inc. | Re-useable aerosol container |
| DK1975181T3 (da) | 1992-10-28 | 2011-06-06 | Genentech Inc | Anvendelse af vaskulære endothelcelle-vækstfaktor-antagonister |
| GB9314893D0 (en) | 1993-07-19 | 1993-09-01 | Zeneca Ltd | Quinazoline derivatives |
| IL129547A (en) | 1994-10-26 | 2001-01-11 | Novartis Ag | Pharmaceutical compositions comprising a macrolide and an acid |
| DE69536015D1 (de) | 1995-03-30 | 2009-12-10 | Pfizer Prod Inc | Chinazolinone Derivate |
| GB9508538D0 (en) | 1995-04-27 | 1995-06-14 | Zeneca Ltd | Quinazoline derivatives |
| US5747498A (en) | 1996-05-28 | 1998-05-05 | Pfizer Inc. | Alkynyl and azido-substituted 4-anilinoquinazolines |
| US5880141A (en) | 1995-06-07 | 1999-03-09 | Sugen, Inc. | Benzylidene-Z-indoline compounds for the treatment of disease |
| EP0836605B1 (fr) | 1995-07-06 | 2002-02-06 | Novartis AG | Pyrrolopyrimidines et leurs procedes de preparation |
| IT1277391B1 (it) * | 1995-07-28 | 1997-11-10 | Romano Deghenghi | Peptidi ciclici analoghi della somatostatina ad attivita' inibitrice dell'ormone della crescita |
| US5760041A (en) | 1996-02-05 | 1998-06-02 | American Cyanamid Company | 4-aminoquinazoline EGFR Inhibitors |
| GB9603095D0 (en) | 1996-02-14 | 1996-04-10 | Zeneca Ltd | Quinazoline derivatives |
| JP3370340B2 (ja) | 1996-04-12 | 2003-01-27 | ワーナー―ランバート・コンパニー | チロシンキナーゼの不可逆的阻害剤 |
| DE69719320T2 (de) * | 1996-06-11 | 2003-12-11 | Novartis Ag, Basel | Kombination eines somatostatin analogs und eines rapamycins |
| EP0907642B1 (fr) | 1996-06-24 | 2005-11-02 | Pfizer Inc. | Derives tricycliques substitues par phenylamino, destines au traitement des maladies hyperproliferatives |
| US5932613A (en) | 1996-07-03 | 1999-08-03 | Millennium Pharmaceuticals, Inc. | Anticancer agents |
| US6258823B1 (en) | 1996-07-12 | 2001-07-10 | Ariad Pharmaceuticals, Inc. | Materials and method for treating or preventing pathogenic fungal infection |
| AU716610B2 (en) | 1996-08-30 | 2000-03-02 | Novartis Ag | Method for producing epothilones, and intermediate products obtained during the production process |
| DE19638745C2 (de) | 1996-09-11 | 2001-05-10 | Schering Ag | Monoklonale Antikörper gegen die extrazelluläre Domäne des menschlichen VEGF - Rezeptorproteins (KDR) |
| AU4342997A (en) | 1996-09-13 | 1998-04-02 | Sugen, Inc. | Use of quinazoline derivatives for the manufacture of a medicament in the reatment of hyperproliferative skin disorders |
| EP0837063A1 (fr) | 1996-10-17 | 1998-04-22 | Pfizer Inc. | Dérivés de 4-aminoquinazoline |
| JP4274583B2 (ja) | 1996-11-18 | 2009-06-10 | ゲゼルシャフト・フュア・ビオテクノロギッシェ・フォルシュンク・ミット・ベシュレンクテル・ハフツング(ゲー・ベー・エフ) | エポチロンc,d,e及びf、製造と薬剤 |
| US6441186B1 (en) | 1996-12-13 | 2002-08-27 | The Scripps Research Institute | Epothilone analogs |
| CO4950519A1 (es) | 1997-02-13 | 2000-09-01 | Novartis Ag | Ftalazinas, preparaciones farmaceuticas que las comprenden y proceso para su preparacion |
| CO4940418A1 (es) | 1997-07-18 | 2000-07-24 | Novartis Ag | Modificacion de cristal de un derivado de n-fenil-2- pirimidinamina, procesos para su fabricacion y su uso |
| GB9721069D0 (en) | 1997-10-03 | 1997-12-03 | Pharmacia & Upjohn Spa | Polymeric derivatives of camptothecin |
| US6194181B1 (en) | 1998-02-19 | 2001-02-27 | Novartis Ag | Fermentative preparation process for and crystal forms of cytostatics |
| JP2002504540A (ja) | 1998-02-25 | 2002-02-12 | スローン−ケッタリング インスティトゥート フォア キャンサー リサーチ | エポチロンの合成、その中間体およびそのアナログ |
| EP1107964B8 (fr) | 1998-08-11 | 2010-04-07 | Novartis AG | Derives d'isoquinoline possedant une activite d'inhibition de l'angiogenese |
| UA71587C2 (uk) | 1998-11-10 | 2004-12-15 | Шерінг Акцієнгезелльшафт | Аміди антранілової кислоти та їхнє застосування як лікарських засобів |
| GB9824579D0 (en) | 1998-11-10 | 1999-01-06 | Novartis Ag | Organic compounds |
| KR100851418B1 (ko) | 1998-11-20 | 2008-08-08 | 코산 바이오사이언시즈, 인코포레이티드 | 에포틸론 및 에포틸론 유도체의 생산을 위한 재조합 방법 및 물질 |
| EP2016953A3 (fr) | 1998-12-22 | 2009-04-15 | Genentech, Inc. | Antagonistes de facteur de croissance cellulaire endothéliale vasculaire et utilisations associées |
| JP4673977B2 (ja) | 1999-03-30 | 2011-04-20 | ノバルティス アーゲー | 炎症性疾患治療用フタラジン誘導体 |
| AU783158B2 (en) | 1999-08-24 | 2005-09-29 | Ariad Pharmaceuticals, Inc. | 28-epirapalogs |
| RU2264405C2 (ru) | 1999-12-06 | 2005-11-20 | Новартис Аг | 40-o-(2-гидрокси)этилрапамицин в кристаллической несольватированной форме, фармацевтическая композиция, содержащая такой макролид в качестве действующего вещества, и способ его получения |
| PE20020354A1 (es) | 2000-09-01 | 2002-06-12 | Novartis Ag | Compuestos de hidroxamato como inhibidores de histona-desacetilasa (hda) |
| SG159378A1 (en) | 2000-11-07 | 2010-03-30 | Novartis Ag | Indolylmaleimide derivatives as protein kinase c inhibitors |
| TWI286074B (en) * | 2000-11-15 | 2007-09-01 | Wyeth Corp | Pharmaceutical composition containing CCI-779 as an antineoplastic agent |
| LT2762140T (lt) * | 2001-02-19 | 2017-06-26 | Novartis Ag | Solidinių smegenų navikų gydymas rapamicino dariniu |
| TWI233359B (en) | 2001-04-06 | 2005-06-01 | Wyeth Corp | Pharmaceutical composition for treating neoplasm |
| CN1309421C (zh) * | 2001-04-06 | 2007-04-11 | 惠氏公司 | 诸如雷帕霉素和吉西他滨或氟尿嘧啶的抗肿瘤联合 |
| TWI296196B (en) | 2001-04-06 | 2008-05-01 | Wyeth Corp | Antineoplastic combinations |
| WO2002098416A2 (fr) * | 2001-06-01 | 2002-12-12 | Wyeth | Combinaisons antineoplasiques |
| US20030008923A1 (en) | 2001-06-01 | 2003-01-09 | Wyeth | Antineoplastic combinations |
| UA77200C2 (en) * | 2001-08-07 | 2006-11-15 | Wyeth Corp | Antineoplastic combination of cci-779 and bkb-569 |
| GB0119249D0 (en) | 2001-08-07 | 2001-10-03 | Novartis Ag | Organic compounds |
| BR0307544A (pt) | 2002-02-01 | 2004-12-07 | Ariad Gene Therapeutics Inc | Compostos contendo fósforos, componentes e composição bem como, sua utilização através de métodos de tratamentos |
| PE20040079A1 (es) | 2002-04-03 | 2004-04-19 | Novartis Ag | Derivados de indolilmaleimida |
| US20060094674A1 (en) | 2002-07-05 | 2006-05-04 | Neel Benjamin G | Combination of mtor inhibitor and a tyrosine kinase inhibitor for the treatment of neoplasms |
| WO2004052359A1 (fr) | 2002-12-09 | 2004-06-24 | The Board Of Regents Of The University Of Texas System | Procede d'inhibition selective de la janus tyrosine kinase 3 (jak3) |
| UA83484C2 (uk) * | 2003-03-05 | 2008-07-25 | Уайт | Спосіб лікування раку грудей комбінацією похідного рапаміцину і інгібітора ароматази - летрозолу, фармацевтична композиція |
| US7160867B2 (en) | 2003-05-16 | 2007-01-09 | Isotechnika, Inc. | Rapamycin carbohydrate derivatives |
| MXPA06007174A (es) | 2003-12-22 | 2006-08-23 | Novartis Ag | Biomarcadores para determinar la sensibilidad de enfermedades proliferativas a inhibidores mtor. |
| US20080207613A1 (en) | 2004-01-12 | 2008-08-28 | Cytopia Research Pty Ltd | Selective Kinase Inhibitors |
| BRPI0507834A (pt) | 2004-02-23 | 2007-07-10 | Sugen Inc | método para tratar o crescimento celular anormal usando inibidores de c-met e de m-tor |
| US7749698B2 (en) | 2004-02-23 | 2010-07-06 | Novartis Ag | p53 wild-type as biomarker for the treatment with mTOR inhibitors in combination with a cytotoxic agent |
| MX2007007212A (es) | 2004-12-15 | 2007-11-07 | Novartis Ag | Combinaciones de agentes terapeuticos para el tratamiento del cancer. |
| US20060160837A1 (en) * | 2004-12-29 | 2006-07-20 | The Brigham And Women's Hospital, Inc. | Rapamycin compounds in the treatment of neurofibromatosis type 1 |
-
2006
- 2006-11-20 EP EP10175197.2A patent/EP2275103B1/fr not_active Revoked
- 2006-11-20 JP JP2008540626A patent/JP2009516671A/ja not_active Withdrawn
- 2006-11-20 BR BRPI0618808-7A patent/BRPI0618808A2/pt not_active Application Discontinuation
- 2006-11-20 PL PL10175197T patent/PL2275103T3/pl unknown
- 2006-11-20 NZ NZ568182A patent/NZ568182A/en unknown
- 2006-11-20 US US12/094,173 patent/US9006224B2/en active Active
- 2006-11-20 NO NO20170956A patent/NO346575B1/no unknown
- 2006-11-20 CA CA2933875A patent/CA2933875C/fr active Active
- 2006-11-20 CA CA2629245A patent/CA2629245C/fr active Active
- 2006-11-20 AU AU2006314444A patent/AU2006314444C1/en active Active
- 2006-11-20 KR KR1020147001555A patent/KR20140012218A/ko not_active Ceased
- 2006-11-20 WO PCT/EP2006/068656 patent/WO2007057457A2/fr not_active Ceased
- 2006-11-20 EP EP06819607A patent/EP1954269A2/fr not_active Withdrawn
- 2006-11-20 NO NO20220050A patent/NO20220050A1/no not_active Application Discontinuation
- 2006-11-20 SI SI200631791T patent/SI2275103T1/sl unknown
- 2006-11-20 DK DK10175197.2T patent/DK2275103T3/da active
- 2006-11-20 PT PT101751972T patent/PT2275103E/pt unknown
- 2006-11-20 RU RU2008124827/15A patent/RU2487711C2/ru active
- 2006-11-20 ES ES10175197.2T patent/ES2481671T3/es active Active
- 2006-11-20 EP EP08162295A patent/EP2022498A3/fr not_active Withdrawn
- 2006-11-20 CN CN2013103848215A patent/CN103446138A/zh active Pending
- 2006-11-20 KR KR1020087014937A patent/KR20080071600A/ko not_active Ceased
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2008
- 2008-05-15 IL IL191475A patent/IL191475A/en active IP Right Grant
- 2008-05-20 MA MA30950A patent/MA29966B1/fr unknown
- 2008-06-16 NO NO20082683A patent/NO344288B1/no unknown
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2010
- 2010-07-07 AU AU2010202866A patent/AU2010202866A1/en not_active Abandoned
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2013
- 2013-04-03 JP JP2013077748A patent/JP5833048B2/ja active Active
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2014
- 2014-06-20 CY CY20141100454T patent/CY1115299T1/el unknown
- 2014-07-22 HR HRP20140708TT patent/HRP20140708T1/hr unknown
- 2014-12-03 JP JP2014245402A patent/JP5963836B2/ja active Active
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2015
- 2015-01-29 US US14/608,644 patent/US20150148294A1/en not_active Abandoned
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2016
- 2016-06-22 NO NO20161045A patent/NO341023B1/no unknown
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2017
- 2017-01-13 US US15/405,501 patent/US20170128425A1/en not_active Abandoned
- 2017-02-21 IL IL250697A patent/IL250697A0/en unknown
- 2017-07-27 IL IL253698A patent/IL253698A0/en unknown
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