MA32624B1 - Derives purines destines a etre utilises dans le traitement de maladies allergiques inflammatoires et infectieuses - Google Patents
Derives purines destines a etre utilises dans le traitement de maladies allergiques inflammatoires et infectieusesInfo
- Publication number
- MA32624B1 MA32624B1 MA33686A MA33686A MA32624B1 MA 32624 B1 MA32624 B1 MA 32624B1 MA 33686 A MA33686 A MA 33686A MA 33686 A MA33686 A MA 33686A MA 32624 B1 MA32624 B1 MA 32624B1
- Authority
- MA
- Morocco
- Prior art keywords
- allergies
- infectious
- treatment
- inflammatory diseases
- purine derivatives
- Prior art date
Links
- 206010020751 Hypersensitivity Diseases 0.000 title 1
- 230000007815 allergy Effects 0.000 title 1
- 208000015181 infectious disease Diseases 0.000 title 1
- 230000002458 infectious effect Effects 0.000 title 1
- 208000027866 inflammatory disease Diseases 0.000 title 1
- 229940083251 peripheral vasodilators purine derivative Drugs 0.000 title 1
- 125000000561 purinyl group Chemical class N1=C(N=C2N=CNC2=C1)* 0.000 title 1
- 239000002551 biofuel Substances 0.000 abstract 3
- 244000005700 microbiome Species 0.000 abstract 2
- 239000000725 suspension Substances 0.000 abstract 2
- 241000195493 Cryptophyta Species 0.000 abstract 1
- 150000001720 carbohydrates Chemical class 0.000 abstract 1
- 235000014633 carbohydrates Nutrition 0.000 abstract 1
- 238000001816 cooling Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 235000016709 nutrition Nutrition 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
La présente invention concerne la culture de micro-organismes hétérotrophes et phototrophes qui est intégrée pour la production de biocombustible pour des biocarburants, où la suspension algacée totale produite est dans un premier temps épaissie, avec recirculation de l'eau en excès dans les récipients de culture, et ensuite thermiquement traitée à température élevée. Après refroidissement, une phase de biocombustible est récupérée conjointement avec une suspension riche en glucides et protéines solubles qui forme une source nutritionnelle/énergétique pour des micro-organismes hétérotrophes.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8777708P | 2008-08-11 | 2008-08-11 | |
| PCT/EP2009/007582 WO2010046115A2 (fr) | 2008-10-23 | 2009-10-16 | Procédé intégré pour la production de biocombustible à partir de micro-organismes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA32624B1 true MA32624B1 (fr) | 2011-09-01 |
Family
ID=41187189
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA33686A MA32624B1 (fr) | 2008-08-11 | 2011-03-08 | Derives purines destines a etre utilises dans le traitement de maladies allergiques inflammatoires et infectieuses |
Country Status (38)
| Country | Link |
|---|---|
| US (7) | US8765772B2 (fr) |
| EP (3) | EP2324026B1 (fr) |
| JP (1) | JP5529867B2 (fr) |
| KR (1) | KR101669939B1 (fr) |
| CN (2) | CN104098568B (fr) |
| AU (1) | AU2009281197B2 (fr) |
| BR (1) | BRPI0917138A2 (fr) |
| CA (1) | CA2733749C (fr) |
| CL (1) | CL2011000301A1 (fr) |
| CO (1) | CO6351791A2 (fr) |
| CR (1) | CR20110116A (fr) |
| CY (1) | CY1119992T1 (fr) |
| DK (2) | DK2324026T3 (fr) |
| DO (1) | DOP2011000048A (fr) |
| EA (1) | EA020631B1 (fr) |
| ES (2) | ES2549154T3 (fr) |
| HK (1) | HK1253532A1 (fr) |
| HR (2) | HRP20150938T1 (fr) |
| HU (2) | HUE036570T2 (fr) |
| IL (1) | IL210757A (fr) |
| LT (1) | LT3000813T (fr) |
| MA (1) | MA32624B1 (fr) |
| ME (1) | ME02274B (fr) |
| MX (2) | MX2011001666A (fr) |
| MY (1) | MY162538A (fr) |
| NO (1) | NO3000813T3 (fr) |
| NZ (2) | NZ590782A (fr) |
| PE (1) | PE20110674A1 (fr) |
| PL (2) | PL3000813T3 (fr) |
| PT (2) | PT3000813T (fr) |
| RS (2) | RS56984B1 (fr) |
| SG (1) | SG192547A1 (fr) |
| SI (2) | SI3000813T1 (fr) |
| SM (2) | SMT201800123T1 (fr) |
| TR (1) | TR201802648T4 (fr) |
| UA (1) | UA103195C2 (fr) |
| WO (1) | WO2010018133A1 (fr) |
| ZA (1) | ZA201100845B (fr) |
Families Citing this family (65)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8012964B2 (en) | 2004-03-26 | 2011-09-06 | Dainippon Sumitomo Pharma Co., Ltd. | 9-substituted 8-oxoadenine compound |
| WO2006108103A1 (fr) * | 2005-04-05 | 2006-10-12 | Pharmacopeia, Inc. | Derives de purine et d'imidazopyridine en vue d'une immunosuppression |
| US20090118263A1 (en) * | 2005-09-22 | 2009-05-07 | Dainippon Sumitomo Pharma Co., Ltd. | Novel Adenine Compound |
| WO2008004948A1 (fr) * | 2006-07-05 | 2008-01-10 | Astrazeneca Ab | Dérivés de la 8-oxoadénine agissant comme modulateurs de tlr7 |
| TW200831105A (en) * | 2006-12-14 | 2008-08-01 | Astrazeneca Ab | Novel compounds |
| EP2125792B1 (fr) * | 2007-02-19 | 2010-12-01 | GlaxoSmithKline LLC | Utilisation de dérivés de purine comme immunomodulateurs |
| JP5329444B2 (ja) * | 2007-03-19 | 2013-10-30 | アストラゼネカ・アクチエボラーグ | Toll様受容体(tlr7)モジュレーターとしての9−置換−8−オキソ−アデニン化合物 |
| SI2132209T1 (sl) * | 2007-03-19 | 2014-05-30 | Astrazeneca Ab | Spojine 9-substituiranega-8-okso-adenina, kot modulatorji Toll-like receptorja (TLR7) |
| AR065784A1 (es) * | 2007-03-20 | 2009-07-01 | Dainippon Sumitomo Pharma Co | Derivados de 8-oxo adenina,medicamentos que los contienen y usos como agentes terapeuticos para enfermedades alergicas, antivirales o antibacterianas. |
| EP2138497A4 (fr) * | 2007-03-20 | 2012-01-04 | Dainippon Sumitomo Pharma Co | Nouveau composé d'adénine |
| EP2155743B1 (fr) * | 2007-05-08 | 2012-08-29 | AstraZeneca AB | Imidazoquinolines dotées de propriétés immuno-modulatrices |
| SI2170888T1 (sl) | 2007-06-29 | 2015-10-30 | Gilead Sciences, Inc. | Purinski derivati in njihova uporaba kot modulatorjev receptorja tipa toll-7 |
| PE20091156A1 (es) | 2007-12-17 | 2009-09-03 | Astrazeneca Ab | Sales de (3-{[[3-(6-amino-2-butoxi-8-oxo-7,8-dihidro-9h-purin-9-il)propil](3-morfolin-4-ilpropil)amino]metil}fenil)acetato de metilo |
| JPWO2009091031A1 (ja) * | 2008-01-17 | 2011-05-26 | 大日本住友製薬株式会社 | アデニン化合物の製造方法 |
| WO2009091032A1 (fr) * | 2008-01-17 | 2009-07-23 | Dainippon Sumitomo Pharma Co., Ltd. | Procédé de production d'un composé d'adénine |
| JP5519670B2 (ja) | 2008-08-11 | 2014-06-11 | グラクソスミスクライン エルエルシー | アレルギー性、炎症性及び感染性疾患治療用のプリン誘導体 |
| US8802684B2 (en) | 2008-08-11 | 2014-08-12 | Glaxosmithkline Llc | Adenine derivatives |
| WO2010018134A1 (fr) | 2008-08-11 | 2010-02-18 | Smithkline Beecham Corporation | Nouveaux dérivés d’adénine |
| UA103195C2 (uk) | 2008-08-11 | 2013-09-25 | Глаксосмитклайн Ллк | Похідні пурину для застосування у лікуванні алергій, запальних та інфекційних захворювань |
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| CA2890201A1 (fr) | 2012-11-20 | 2014-05-30 | Glaxosmithkline Llc | Nouveaux composes |
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| TWI733652B (zh) | 2014-07-11 | 2021-07-21 | 美商基利科學股份有限公司 | 用於治療HIV之toll樣受體調節劑 |
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| CN112839673A (zh) | 2018-07-23 | 2021-05-25 | 日本国立感染症研究所所长代表之日本国 | 包含流感疫苗的组合物 |
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