MA32981B1 - Regime posologique pour un agoniste du recepteur s1p - Google Patents

Regime posologique pour un agoniste du recepteur s1p

Info

Publication number
MA32981B1
MA32981B1 MA34034A MA34034A MA32981B1 MA 32981 B1 MA32981 B1 MA 32981B1 MA 34034 A MA34034 A MA 34034A MA 34034 A MA34034 A MA 34034A MA 32981 B1 MA32981 B1 MA 32981B1
Authority
MA
Morocco
Prior art keywords
receptor agonist
dosing system
daily dose
receptor
analogues
Prior art date
Application number
MA34034A
Other languages
Arabic (ar)
English (en)
Inventor
Robert Schmouder
Thomas Dumortier
Olivier David
Michael Looby
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41667217&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA32981(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MA32981B1 publication Critical patent/MA32981B1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/10—Phosphatides, e.g. lecithin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Transplantation (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention porte sur des modulateurs ou agonistes du récepteur S1P qui sont administrés selon un régime posologique, dans lequel durant les jours initiaux de traitement, le dosage quotidien est inférieur au dosage quotidien standard.
MA34034A 2008-12-22 2009-12-21 Regime posologique pour un agoniste du recepteur s1p MA32981B1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US13967208P 2008-12-22 2008-12-22
US21853009P 2009-06-19 2009-06-19
US24671509P 2009-09-29 2009-09-29
PCT/US2009/068888 WO2010075239A1 (fr) 2008-12-22 2009-12-21 Régime posologique pour un agoniste du récepteur s1p

Publications (1)

Publication Number Publication Date
MA32981B1 true MA32981B1 (fr) 2012-01-02

Family

ID=41667217

Family Applications (1)

Application Number Title Priority Date Filing Date
MA34034A MA32981B1 (fr) 2008-12-22 2009-12-21 Regime posologique pour un agoniste du recepteur s1p

Country Status (43)

Country Link
US (12) US20110257133A1 (fr)
EP (7) EP3677260A1 (fr)
JP (7) JP2012513401A (fr)
KR (1) KR101347919B1 (fr)
CN (1) CN102264359A (fr)
AR (1) AR074826A1 (fr)
AU (1) AU2009330176C9 (fr)
BR (1) BRPI0923500A2 (fr)
CA (1) CA2747802C (fr)
CL (2) CL2011001529A1 (fr)
CO (1) CO6390117A2 (fr)
CR (1) CR20110274A (fr)
CU (1) CU20110136A7 (fr)
CY (5) CY1116990T1 (fr)
DK (4) DK4098256T5 (fr)
EA (1) EA201100978A1 (fr)
EC (1) ECSP11011222A (fr)
ES (4) ES3017254T3 (fr)
FI (2) FI4098256T3 (fr)
FR (2) FR20C1060I1 (fr)
HN (1) HN2011001759A (fr)
HR (4) HRP20250568T1 (fr)
HU (6) HUE048717T4 (fr)
IL (3) IL213170A0 (fr)
LT (5) LT3453387T (fr)
LU (1) LUC00183I2 (fr)
MA (1) MA32981B1 (fr)
ME (2) ME03594B (fr)
MX (3) MX2011006623A (fr)
NO (1) NO2020038I1 (fr)
NZ (1) NZ593065A (fr)
PE (1) PE20120337A1 (fr)
PL (4) PL3409274T3 (fr)
PT (4) PT4098256T (fr)
RS (3) RS60666B1 (fr)
SG (1) SG171404A1 (fr)
SI (4) SI2379067T1 (fr)
SM (2) SMT202000441T1 (fr)
TN (1) TN2011000272A1 (fr)
TW (1) TW201028143A (fr)
UY (1) UY32352A (fr)
WO (1) WO2010075239A1 (fr)
ZA (2) ZA201103863B (fr)

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NZ598534A (en) 2009-09-29 2014-03-28 Novartis Ag Dosage regimen of an s1p receptor modulator
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JP5856980B2 (ja) 2010-01-27 2016-02-10 アリーナ ファーマシューティカルズ， インコーポレイテッド （Ｒ）−２−（７−（４−シクロペンチル−３−（トリフルオロメチル）ベンジルオキシ）−１，２，３，４−テトラヒドロシクロペンタ［ｂ］インドール−３−イル）酢酸およびその塩の調製のためのプロセス
BR112012028248A2 (pt) * 2010-05-06 2016-08-02 Novartis Ag derivados de sulfeto de diarila, seu uso, e kit
EP2455080A1 (fr) * 2010-11-23 2012-05-23 Almirall, S.A. Agonistes de récepteur S1P1 à utiliser dans le traitement de la sclérose en plaques
FR2968556B1 (fr) 2010-12-13 2013-12-27 Centre Nat Rech Scient Inhibiteurs des infections a vih et leurs utilisations
JP6111202B2 (ja) 2011-01-07 2017-04-05 ノバルティス アーゲー 免疫抑制製剤
EP3502236B1 (fr) 2011-02-18 2023-08-23 The Scripps Research Institute Différenciation dirigée de cellules précurseurs d'oligodendrocytes vers un destin de cellules myélinisantes
AR085749A1 (es) 2011-04-01 2013-10-23 Novartis Ag Formulaciones
US9592268B2 (en) 2011-05-23 2017-03-14 Cornell University Endothelium protective materials and methods of use
TW201320994A (zh) * 2011-10-11 2013-06-01 Novartis Ag 投藥療程
SMT202000298T1 (it) 2012-08-17 2020-07-08 Actelion Pharmaceuticals Ltd Processo per la produzione di (2z,5z)-5-(3-cloro-4((r)-2,3-diidrossipropossi) benziliden)-2-(propilimmino)-3-(o-tolil)tiazolidin-4-one e intermedio usato in detto processo
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US10675254B2 (en) 2013-10-11 2020-06-09 Teikoku Seiyaku Co., Ltd. Sphingosine-1-phosphate receptor agonist iontophoretic devices and methods of using the same
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EP3129020A1 (fr) * 2014-04-10 2017-02-15 Novartis AG Régime posologique de modulateur s1p à libération immédiate
KR20200013086A (ko) 2014-12-11 2020-02-05 액테리온 파마슈티칼 리미티드 선택적 s1p1 수용체 효능제에 대한 투약 섭생
MA41139B1 (fr) 2014-12-11 2026-02-27 Laboratoires Juvise Pharmaceuticals Combinaison pharmaceutique comprenant du ponesimod et son utilisation dans le traitement de la sclérose en plaque
PL3242666T3 (pl) 2015-01-06 2025-02-17 Arena Pharmaceuticals, Inc. Związek do zastosowania w leczeniu dolegliwości związanych z receptorem s1p1
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BR112017027656B1 (pt) 2015-06-22 2023-12-05 Arena Pharmaceuticals, Inc. Hábito cristalino de placa livre de sal de l-arginina de ácido (r)-2-(7-(4- ciclopentil-3-(trifluorometil)benzilóxi)- 1,2,3,4-tetra-hidrociclo-penta[b]indol-3- il)acético, composição farmacêutica que o compreende, seus usos e método de preparação do mesmo
MX2019009841A (es) 2017-02-16 2020-01-30 Arena Pharm Inc Compuestos y metodos para el tratamiento de la colangitis biliar primaria.
MX2019009843A (es) 2017-02-16 2020-01-30 Arena Pharm Inc Compuestos y metodos para el tratamiento de la enfermedad inflamatoria intestinal con manifestaciones extraintestinales.
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JP7749552B2 (ja) 2019-10-31 2025-10-06 イドルシア・ファーマシューティカルズ・リミテッド Ｃｘｃｒ７アンタゴニストのｓ１ｐ１受容体調節剤との合剤
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Also Published As

Publication number Publication date
CY1123255T1 (el) 2021-10-29
EP3453387B1 (fr) 2020-06-03
ES2760607T3 (es) 2020-05-14
JP2012513401A (ja) 2012-06-14
US20140066657A1 (en) 2014-03-06
HUE048717T2 (hu) 2020-08-28
US20200330407A1 (en) 2020-10-22
US20100160259A1 (en) 2010-06-24
JP2014144970A (ja) 2014-08-14
BRPI0923500A2 (pt) 2018-05-29
IL213170A0 (en) 2011-07-31
DK2379067T3 (en) 2015-12-07
HRP20201167T1 (hr) 2020-12-11
EP4098256B9 (fr) 2025-06-18
PL3453387T3 (pl) 2020-11-02
HUE026869T2 (en) 2016-08-29
HUE071189T2 (hu) 2025-08-28
LT3409274T (lt) 2020-02-10
US20220142949A1 (en) 2022-05-12
EP3677260A1 (fr) 2020-07-08
HN2011001759A (es) 2013-11-26
DK4098256T5 (da) 2025-07-21
CA2747802C (fr) 2021-02-09
DK3453387T3 (da) 2020-08-10
DK4098256T3 (da) 2025-04-22
KR101347919B1 (ko) 2014-01-07
CY2020036I1 (el) 2021-03-12
FI4098256T3 (fi) 2025-03-31
ME03594B (fr) 2020-07-20
MX2011006623A (es) 2011-07-12
RS66784B9 (sr) 2025-08-29
AU2009330176C1 (en) 2016-12-08
EA201100978A1 (ru) 2012-01-30
MX2021010759A (es) 2022-07-19
SI4098256T1 (sl) 2025-06-30
SI3453387T1 (sl) 2020-10-30
EP3409274B1 (fr) 2019-11-20
PL3409274T3 (pl) 2020-06-01
EP2379067B1 (fr) 2015-09-02
JP2024129030A (ja) 2024-09-26
NZ593065A (en) 2012-11-30
EP3453387A1 (fr) 2019-03-13
ES3017254T3 (en) 2025-05-12
HRP20192175T1 (hr) 2020-03-20
ME03802B (fr) 2021-04-20
FIC20253002I1 (fi) 2025-05-23
HUE048717T4 (hu) 2022-02-28
HRP20250568T1 (hr) 2025-07-04
JP2016135752A (ja) 2016-07-28
AU2009330176C9 (en) 2017-01-05
EP2379067A1 (fr) 2011-10-26
EP3409274A1 (fr) 2018-12-05
LT3453387T (lt) 2020-08-25
CY2025012I1 (el) 2026-02-25
ES2552823T3 (es) 2015-12-02
DK3409274T3 (da) 2019-12-16
US20170189353A1 (en) 2017-07-06
HUS2000046I1 (hu) 2020-12-28
LUC00183I2 (fr) 2024-07-01
US20140148415A1 (en) 2014-05-29
RS66784B1 (sr) 2025-06-30
CU20110136A7 (es) 2012-01-31
TW201028143A (en) 2010-08-01
CY2020036I2 (el) 2021-06-25
LTPA2020005I1 (lt) 2020-12-10
ECSP11011222A (es) 2011-08-31
FR20C1060I1 (fr) 2020-12-25
US20180289638A1 (en) 2018-10-11
HUE052048T2 (hu) 2021-04-28
JP2019167360A (ja) 2019-10-03
HUS2500026I1 (hu) 2025-07-28
EP4098256A1 (fr) 2022-12-07
JP2022103194A (ja) 2022-07-07
AR074826A1 (es) 2011-02-16
ZA201103863B (en) 2012-10-31
AU2009330176B2 (en) 2014-03-06
PL4098256T3 (pl) 2025-06-09
US20110257133A1 (en) 2011-10-20
IL278914A (en) 2021-01-31
CY1116990T1 (el) 2017-04-05
ES2810823T3 (es) 2021-03-09
CY2025012I2 (el) 2026-02-25
CY1122812T1 (el) 2021-05-05
SG171404A1 (en) 2011-07-28
FR25C1012I1 (fr) 2025-06-13
EP4098256B1 (fr) 2025-02-26
NO2020038I1 (no) 2020-11-18
EP2907511A1 (fr) 2015-08-19
PT4098256T (pt) 2025-04-10
LTPA2025520I1 (fr) 2025-06-25
SI2379067T1 (sl) 2016-01-29
KR20110096175A (ko) 2011-08-29
SMT202000441T1 (it) 2020-09-10
RS59857B1 (sr) 2020-02-28
UY32352A (es) 2010-07-30
WO2010075239A1 (fr) 2010-07-01
HRP20151190T1 (hr) 2016-01-01
CR20110274A (es) 2011-07-19
EP3120844A1 (fr) 2017-01-25
PE20120337A1 (es) 2012-04-24
JP2017141238A (ja) 2017-08-17
MX385959B (es) 2025-03-18
CL2011001529A1 (es) 2012-02-24
US20160263061A1 (en) 2016-09-15
PT3409274T (pt) 2019-12-17
US20160081949A1 (en) 2016-03-24
PT2379067E (pt) 2015-12-23
PL2379067T3 (pl) 2016-02-29
SMT202000054T1 (it) 2020-03-13
IL274756A (en) 2020-07-30
CA2747802A1 (fr) 2010-07-01
LT4098256T (lt) 2025-06-10
TN2011000272A1 (en) 2012-12-17
PT3453387T (pt) 2020-08-11
US20190091180A1 (en) 2019-03-28
US20250262171A1 (en) 2025-08-21
CO6390117A2 (es) 2012-02-29
SI3409274T1 (sl) 2020-03-31
RS60666B1 (sr) 2020-09-30
CN102264359A (zh) 2011-11-30
JP7329965B2 (ja) 2023-08-21
ZA201205942B (en) 2013-03-27
AU2009330176A1 (en) 2011-07-07
CL2013001558A1 (es) 2013-10-25

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