MA34646B1 - Procedes de traitement du psoriasis en utilisant des antagonistes d'il-17 - Google Patents
Procedes de traitement du psoriasis en utilisant des antagonistes d'il-17Info
- Publication number
- MA34646B1 MA34646B1 MA35872A MA35872A MA34646B1 MA 34646 B1 MA34646 B1 MA 34646B1 MA 35872 A MA35872 A MA 35872A MA 35872 A MA35872 A MA 35872A MA 34646 B1 MA34646 B1 MA 34646B1
- Authority
- MA
- Morocco
- Prior art keywords
- antagonists
- methods
- treating psoriasis
- antibody
- binding molecule
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La présente invention concerne de nouveaux régimes pour le traitement du psoriasis, qui utilisent une quantité thérapeutiquement efficace d'un antagoniste de IL-17, tel qu'une molécule de liaison à IL-17, par exemple un anticorps de IL-17 (tel que l'anticorps secukinumab), ou une molécule de liaison à un récepteur de IL-17, par exemple un anticorps du récepteur de IL-17.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39138810P | 2010-10-08 | 2010-10-08 | |
| PCT/EP2011/067522 WO2012045848A1 (fr) | 2010-10-08 | 2011-10-07 | Méthodes de traitement du psoriasis au moyen d'antagonistes de il-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA34646B1 true MA34646B1 (fr) | 2013-11-02 |
Family
ID=44759699
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA35872A MA34646B1 (fr) | 2010-10-08 | 2013-05-03 | Procedes de traitement du psoriasis en utilisant des antagonistes d'il-17 |
Country Status (28)
| Country | Link |
|---|---|
| US (9) | US9717791B2 (fr) |
| EP (5) | EP3299390A1 (fr) |
| JP (2) | JP5537740B2 (fr) |
| KR (3) | KR20130110179A (fr) |
| CN (2) | CN103154031A (fr) |
| AU (1) | AU2011311482B2 (fr) |
| BR (1) | BR112013008501A2 (fr) |
| CA (1) | CA2813900C (fr) |
| CL (1) | CL2013000930A1 (fr) |
| CY (1) | CY1119942T1 (fr) |
| DK (1) | DK2625199T3 (fr) |
| ES (1) | ES2660770T3 (fr) |
| HK (1) | HK1247932A1 (fr) |
| HR (1) | HRP20180301T1 (fr) |
| HU (1) | HUE038334T2 (fr) |
| IL (1) | IL225310A (fr) |
| LT (1) | LT2625199T (fr) |
| MA (1) | MA34646B1 (fr) |
| MX (1) | MX356279B (fr) |
| NO (1) | NO2625199T3 (fr) |
| PH (1) | PH12013500660B1 (fr) |
| PL (1) | PL2625199T3 (fr) |
| PT (1) | PT2625199T (fr) |
| RU (2) | RU2665954C1 (fr) |
| SG (1) | SG188979A1 (fr) |
| SI (1) | SI2625199T1 (fr) |
| TW (2) | TWI564022B (fr) |
| WO (1) | WO2012045848A1 (fr) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7767206B2 (en) | 2006-10-02 | 2010-08-03 | Amgen Inc. | Neutralizing determinants of IL-17 Receptor A and antibodies that bind thereto |
| JO3244B1 (ar) | 2009-10-26 | 2018-03-08 | Amgen Inc | بروتينات ربط مستضادات il – 23 البشرية |
| PH12012501364A1 (en) | 2010-01-15 | 2012-10-22 | Amgen K A Inc | Antibody formulation and therapeutic regimens |
| EP2571901B1 (fr) | 2010-05-20 | 2019-01-02 | Ablynx N.V. | Matériaux biologiques associés à her3 |
| CN103154031A (zh) | 2010-10-08 | 2013-06-12 | 诺华有限公司 | 利用il-17拮抗剂治疗牛皮癣的方法 |
| BR112013011176A2 (pt) | 2010-11-05 | 2020-09-01 | Novartis Ag | métodos de tratamento de artrite reumatoide usando antagonistas de il-17 |
| UA117218C2 (uk) | 2011-05-05 | 2018-07-10 | Мерк Патент Гмбх | Поліпептид, спрямований проти il-17a, il-17f та/або il17-a/f |
| EP2783014A1 (fr) * | 2011-11-21 | 2014-10-01 | Novartis AG | Procédés de traitement du rhumatisme psoriasique (psa) utilisant des antagonistes d'il-17 et des allèles répondeurs ou non répondeurs à psa |
| SG11201507482UA (en) * | 2013-03-15 | 2015-10-29 | Amgen Inc | Methods for treating psoriasis using an anti-il-23 antibody |
| SG11201507483PA (en) * | 2013-03-15 | 2015-10-29 | Amgen Inc | Methods for treating crohn's disease using an anti-il23 antibody |
| WO2015022656A1 (fr) | 2013-08-15 | 2015-02-19 | Novartis Ag | Méthodes de traitement du psoriasis pustuleux généralisé (gpp) au moyen d'antagonistes d'il-17 |
| US11421025B2 (en) | 2013-12-27 | 2022-08-23 | Osaka University | Treatment of IL-17A diseases |
| RU2577228C2 (ru) * | 2014-03-14 | 2016-03-10 | Закрытое Акционерное Общество "Биокад" | Анти-il-17-антитела, способ их получения и способ применения |
| CA2944605C (fr) * | 2014-03-31 | 2023-10-17 | Kirin-Amgen, Inc. | Procedes de traitement du psoriasis des ongles et du cuir chevelu |
| US10220076B2 (en) | 2014-05-15 | 2019-03-05 | Incube Labs, Llc | Pharmaceutical compositions and methods for fabrication of solid masses comprising glucose regulating proteins |
| US11548940B2 (en) * | 2014-05-15 | 2023-01-10 | Rani Therapeutics, Llc | Anti-interleukin antibody preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| JP6663910B2 (ja) * | 2014-08-26 | 2020-03-13 | アムジェン ケー・エー,インコーポレイテッド | 抗TNF−α抗体療法を受けた乾癬患者を治療するための方法 |
| CN115957326A (zh) * | 2014-09-10 | 2023-04-14 | 诺华股份有限公司 | 使用il-17拮抗剂抑制银屑病关节炎患者的结构损伤进展 |
| AR103172A1 (es) | 2014-12-22 | 2017-04-19 | Novartis Ag | Reducción selectiva de residuos de cisteina en anticuerpos il-17 |
| AR103173A1 (es) | 2014-12-22 | 2017-04-19 | Novarits Ag | Productos farmacéuticos y composiciones líquidas estables de anticuerpos il-17 |
| EP3265493B1 (fr) | 2015-03-02 | 2024-01-10 | 180 Therapeutics LP | Méthode de traitement d'un trouble fibrotique localisé à l'aide d'un antagoniste de l'il-33 |
| EP3167892A1 (fr) | 2015-11-10 | 2017-05-17 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Procédés et compositions pharmaceutiques pour la prévention ou le traitement de maladies intestinales inflammatoires |
| CN116059350A (zh) * | 2015-10-27 | 2023-05-05 | Ucb生物制药有限责任公司 | 使用抗-il-17a/f抗体的治疗方法 |
| WO2018015880A1 (fr) * | 2016-07-19 | 2018-01-25 | Novartis Ag | Procédés de traitement du psoriasis de type en plaques d'apparition récente au moyen d'antagonistes de l'il-17 |
| JP2019505516A (ja) * | 2016-11-28 | 2019-02-28 | ノバルティス アーゲー | インターロイキン−17(il−17)アンタゴニストを使用してざ瘡を治療する方法 |
| WO2018158741A1 (fr) * | 2017-03-03 | 2018-09-07 | Novartis Ag | Modification de la maladie du psoriasis suite à un traitement à long terme avec un antagoniste de l'il-17 |
| CN111032691A (zh) * | 2017-08-23 | 2020-04-17 | 伊莱利利公司 | 生殖器银屑病的治疗 |
| TWI725532B (zh) * | 2018-09-11 | 2021-04-21 | 美商美國禮來大藥廠 | 治療牛皮癬之方法 |
| US20220267432A1 (en) | 2019-07-30 | 2022-08-25 | Jiangsu Hengrui Medicine Co., Ltd. | Method for treating autoimmune disease by il-17 antagonist |
| TW202126329A (zh) | 2019-09-20 | 2021-07-16 | 瑞士商諾華公司 | 使用白細胞介素-17(il-17)拮抗劑治療自體免疫性疾病之方法 |
| WO2022127842A1 (fr) * | 2020-12-17 | 2022-06-23 | 上海华奥泰生物药业股份有限公司 | Anticorps bispécifique ciblant il-17a et il-36r et son application |
| WO2022184114A1 (fr) * | 2021-03-03 | 2022-09-09 | 苏州盛迪亚生物医药有限公司 | Procédé de traitement de maladies auto-immunes et d'inflammations avec un anticorps anti-il-17 |
| WO2023186174A1 (fr) * | 2022-04-01 | 2023-10-05 | Zai Lab (Shanghai) Co., Ltd. | Formulation topique comprenant une molécule de liaison à l'il-17 et ses utilisations |
| CN116593718B (zh) * | 2023-07-18 | 2023-09-15 | 军科正源(北京)药物研究有限责任公司 | 用于检测司库奇尤单抗抗药性抗体的试剂 |
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| US5250442A (en) | 1993-04-08 | 1993-10-05 | Orestes Cabezas | Method of treating rheumatoid arthritis using tetracycline |
| US6309636B1 (en) | 1995-09-14 | 2001-10-30 | Cancer Research Institute Of Contra Costa | Recombinant peptides derived from the Mc3 anti-BA46 antibody, methods of use thereof, and methods of humanizing antibody peptides |
| GB9422306D0 (en) * | 1994-11-04 | 1994-12-21 | Sandoz Ltd | Organic compounds |
| US6093745A (en) * | 1997-11-25 | 2000-07-25 | Psorx, L.L.C. | Methods and composition for treating skin proliferative diseases |
| US20050147609A1 (en) | 1998-05-15 | 2005-07-07 | Genentech, Inc. | Use of anti-IL-17 antibody for the treatment of cartilage damaged by osteoarthritis |
| JP2000186046A (ja) | 1998-10-14 | 2000-07-04 | Snow Brand Milk Prod Co Ltd | 慢性関節リウマチ治療剤及び診断方法 |
| JP4159682B2 (ja) | 1998-12-22 | 2008-10-01 | 株式会社クラレ | 止血材 |
| WO2002032374A2 (fr) * | 2000-10-18 | 2002-04-25 | Immunex Corporation | Methodes de traitement de troubles induits par l'il-18 |
| US20090280065A1 (en) * | 2006-04-10 | 2009-11-12 | Willian Mary K | Uses and Compositions for Treatment of Psoriasis |
| US8039642B2 (en) | 2003-12-09 | 2011-10-18 | Life Technologies Corporation | Pyrenyloxysulfonic acid fluorescent agents |
| TW201705980A (zh) * | 2004-04-09 | 2017-02-16 | 艾伯維生物技術有限責任公司 | 用於治療TNFα相關失調症之多重可變劑量療法 |
| GB0417487D0 (en) * | 2004-08-05 | 2004-09-08 | Novartis Ag | Organic compound |
| ES2569409T3 (es) | 2005-03-08 | 2016-05-10 | Pfizer Products Inc. | Composiciones de anticuerpo anti-CTLA-4 |
| US20080199460A1 (en) * | 2005-09-01 | 2008-08-21 | Schering Corporation | Use of IL-23 and IL-17 antagonists to treat autoimmune ocular inflammatory disease |
| MY149159A (en) | 2005-11-15 | 2013-07-31 | Hoffmann La Roche | Method for treating joint damage |
| EP1963368B3 (fr) | 2005-12-13 | 2020-06-10 | Eli Lilly And Company | Anticorps anti-il-17 |
| BRPI0706788A2 (pt) | 2006-01-31 | 2011-04-05 | Novartis Ag | anticorpos antagonistas il-17 |
| TW200815469A (en) * | 2006-06-23 | 2008-04-01 | Astrazeneca Ab | Compounds |
| CA2662350A1 (fr) | 2006-09-05 | 2008-03-13 | Medarex, Inc. | Anticorps contre les proteines morphogeniques osseuses et les recepteurs de celles-ci et procedes d'utilisation de ceux-ci |
| US7767206B2 (en) | 2006-10-02 | 2010-08-03 | Amgen Inc. | Neutralizing determinants of IL-17 Receptor A and antibodies that bind thereto |
| RU2367429C2 (ru) | 2007-01-30 | 2009-09-20 | Государственное учреждение Научно-исследовательский институт клинической иммунологии СО РАМН | Способ лечения псориаза |
| CA2682292A1 (fr) | 2007-03-30 | 2008-10-09 | Medimmune, Llc | Formulation aqueuse comportant un anticorps anti-interferon alpha humain |
| EP2152318A4 (fr) * | 2007-06-01 | 2011-12-07 | Abbott Biotech Ltd | Compositions et utilisations pour le traitement du psoriasis et de la maladie de crohn |
| US20100239590A1 (en) | 2007-06-20 | 2010-09-23 | Schering Corporation | Joint destruction biomarkers for anti-il-17a therapy of inflammatory joint disease |
| US7720605B2 (en) | 2007-06-22 | 2010-05-18 | Weyerhaeuser Nr Company | Identifying vegetation attributes from LiDAR data |
| RU2341272C1 (ru) | 2007-10-22 | 2008-12-20 | Левон Никитович Мкртчян | Средство для неспецифической иммунотерапии |
| CA2726087A1 (fr) | 2008-06-03 | 2009-12-10 | Tariq Ghayur | Immunoglobulines a deux domaines variables et leurs utilisations |
| US20090301682A1 (en) | 2008-06-05 | 2009-12-10 | Baker Hughes Incorporated | Casting furnace method and apparatus |
| CN102149825B (zh) | 2008-07-08 | 2015-07-22 | Abbvie公司 | 前列腺素e2双重可变结构域免疫球蛋白及其用途 |
| NZ591484A (en) | 2008-09-29 | 2012-09-28 | Roche Glycart Ag | Antibodies against human il 17 and uses thereof |
| JP5933975B2 (ja) | 2008-11-12 | 2016-06-15 | メディミューン,エルエルシー | 抗体製剤 |
| WO2010065491A2 (fr) | 2008-12-01 | 2010-06-10 | Carolus Therapeutics, Inc. | Procédés de traitement de troubles inflammatoires |
| TWI541021B (zh) | 2009-03-05 | 2016-07-11 | 艾伯維有限公司 | Il-17結合蛋白 |
| CN103154031A (zh) | 2010-10-08 | 2013-06-12 | 诺华有限公司 | 利用il-17拮抗剂治疗牛皮癣的方法 |
| BR112013011176A2 (pt) | 2010-11-05 | 2020-09-01 | Novartis Ag | métodos de tratamento de artrite reumatoide usando antagonistas de il-17 |
| TW201307845A (zh) | 2010-12-13 | 2013-02-16 | Novartis Ag | 預測方法及利用il-17拮抗劑治療關節炎的方法 |
| EP2783014A1 (fr) | 2011-11-21 | 2014-10-01 | Novartis AG | Procédés de traitement du rhumatisme psoriasique (psa) utilisant des antagonistes d'il-17 et des allèles répondeurs ou non répondeurs à psa |
| WO2013158821A2 (fr) | 2012-04-20 | 2013-10-24 | Novartis Ag | Procédés de traitement de la spondylarthrite ankylosante en utilisant des antagonistes de il-17 |
| WO2014155278A2 (fr) | 2013-03-26 | 2014-10-02 | Novartis Ag | Méthodes de traitement de maladies auto-immunes à l'aide d'antagonistes de l'il -17 |
| AR103173A1 (es) | 2014-12-22 | 2017-04-19 | Novarits Ag | Productos farmacéuticos y composiciones líquidas estables de anticuerpos il-17 |
| CA3002622A1 (fr) | 2015-10-19 | 2017-04-27 | Novartis Ag | Procedes de traitement d'une spondylarthrite axiale non radiographique utilisant des antagonistes d'interleukine -17 (il -17) |
| US11280479B2 (en) | 2017-10-18 | 2022-03-22 | The Sloan Company | Sign box light module |
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2011
- 2011-10-07 CN CN2011800487322A patent/CN103154031A/zh active Pending
- 2011-10-07 TW TW105116323A patent/TWI564022B/zh active
- 2011-10-07 EP EP17195148.6A patent/EP3299390A1/fr not_active Withdrawn
- 2011-10-07 LT LTEP11764764.4T patent/LT2625199T/lt unknown
- 2011-10-07 CA CA2813900A patent/CA2813900C/fr active Active
- 2011-10-07 JP JP2013532213A patent/JP5537740B2/ja active Active
- 2011-10-07 US US13/876,367 patent/US9717791B2/en active Active
- 2011-10-07 EP EP25216056.9A patent/EP4670788A3/fr active Pending
- 2011-10-07 MX MX2013003916A patent/MX356279B/es active IP Right Grant
- 2011-10-07 BR BR112013008501A patent/BR112013008501A2/pt active Search and Examination
- 2011-10-07 SG SG2013018486A patent/SG188979A1/en unknown
- 2011-10-07 SI SI201131408T patent/SI2625199T1/en unknown
- 2011-10-07 DK DK11764764.4T patent/DK2625199T3/en active
- 2011-10-07 PL PL11764764T patent/PL2625199T3/pl unknown
- 2011-10-07 IL IL225310A patent/IL225310A/en active IP Right Grant
- 2011-10-07 KR KR1020137011792A patent/KR20130110179A/ko not_active Ceased
- 2011-10-07 EP EP20187002.9A patent/EP3792281A1/fr not_active Ceased
- 2011-10-07 TW TW100136608A patent/TWI548419B/zh active
- 2011-10-07 RU RU2016120615A patent/RU2665954C1/ru active
- 2011-10-07 CN CN201710261381.2A patent/CN107029234A/zh active Pending
- 2011-10-07 KR KR1020147036815A patent/KR20150018595A/ko not_active Withdrawn
- 2011-10-07 NO NO11764764A patent/NO2625199T3/no unknown
- 2011-10-07 KR KR1020147018691A patent/KR101620771B1/ko active Active
- 2011-10-07 PT PT117647644T patent/PT2625199T/pt unknown
- 2011-10-07 HR HRP20180301TT patent/HRP20180301T1/hr unknown
- 2011-10-07 RU RU2013120957/15A patent/RU2591083C2/ru active
- 2011-10-07 EP EP11764764.4A patent/EP2625199B1/fr active Active
- 2011-10-07 ES ES11764764.4T patent/ES2660770T3/es active Active
- 2011-10-07 HU HUE11764764A patent/HUE038334T2/hu unknown
- 2011-10-07 EP EP22186296.4A patent/EP4137514A1/fr active Pending
- 2011-10-07 WO PCT/EP2011/067522 patent/WO2012045848A1/fr not_active Ceased
- 2011-10-07 AU AU2011311482A patent/AU2011311482B2/en active Active
- 2011-10-07 PH PH1/2013/500660A patent/PH12013500660B1/en unknown
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2013
- 2013-04-05 CL CL2013000930A patent/CL2013000930A1/es unknown
- 2013-05-03 MA MA35872A patent/MA34646B1/fr unknown
- 2013-12-09 JP JP2013253745A patent/JP2014114288A/ja not_active Withdrawn
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2017
- 2017-06-22 US US15/630,577 patent/US10583190B2/en active Active
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2018
- 2018-02-22 CY CY20181100220T patent/CY1119942T1/el unknown
- 2018-06-01 HK HK18107225.2A patent/HK1247932A1/en unknown
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2019
- 2019-12-19 US US16/720,351 patent/US11534490B2/en active Active
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2020
- 2020-12-18 US US17/127,738 patent/US20210113688A1/en not_active Abandoned
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2021
- 2021-02-02 US US17/165,724 patent/US20210162044A1/en not_active Abandoned
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2022
- 2022-12-02 US US18/061,227 patent/US20230321231A1/en active Pending
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2024
- 2024-12-16 US US18/983,030 patent/US12551554B2/en active Active
- 2024-12-16 US US18/983,037 patent/US12594332B2/en active Active
- 2024-12-16 US US18/983,034 patent/US12594331B2/en active Active
Also Published As
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|---|---|---|
| MA34646B1 (fr) | Procedes de traitement du psoriasis en utilisant des antagonistes d'il-17 | |
| MA34647B1 (fr) | Procedes de traitement de la polyarthriterhumatoide en utilisant des antagonistes dil-17 | |
| MA34175B1 (fr) | Anticorps anti-cxcr4 humanisés pour le traitement de cancer | |
| EA201170624A1 (ru) | Изоникотинамидные антагонисты рецепторов орексинов | |
| EA200900828A1 (ru) | Соединения и композиции в качестве ингибиторов активности каннабиноидного рецептора 1 | |
| MA44312A (fr) | Anticorps et leurs méthodes d'utilisation | |
| MA37946A1 (fr) | Traitement de la polyarthrite rhumatoïde | |
| DE602005020655D1 (de) | Carboxamid-spirolactam-cgrp-rezeptor-antagonisten | |
| MA32928B1 (fr) | Anticorps anti-cxcr4 et leur utilisation pour le traitement du cancer | |
| EA201290515A1 (ru) | Аминопиримидины в качестве syk ингибиторов | |
| EA200970337A1 (ru) | Ингибиторы котранспортера натрий-глюкозы 2 и способы их применения | |
| MA29330B1 (fr) | Antagonistes de recepteur de pgd2 pour le traitement des maladies inflammatoires. | |
| ATE464305T1 (de) | Bicyclische anilidspirolactame als antagonisten des cgrp-rezeptors | |
| NO20092470L (no) | Substituerte diazepanforbindelser som orexinreseptorantagonister | |
| EP1608627A4 (fr) | Antagonistes des recepteurs du cgrp spirohydantoine anilides bicycliques | |
| EP1861399A4 (fr) | Antagonistes du recepteur du cgrp | |
| EP1606286A4 (fr) | Antagonistes benodiazepine spirohydantoin des recepteurs de cgrp | |
| MA30358B1 (fr) | Quinazolines pour l'inhibition de pdk1 | |
| MA35404B1 (fr) | Composés pour le traitement de la toxicomanie | |
| ATE556060T1 (de) | Monocyclische anilidspirohydantoine als cgrp- rezeptorantagonisten | |
| DE602008005771D1 (de) | Disubstituierte alkyl-8-azabicycloä3.2.1üoktan-verbindungen als mu-opioid-rezeptorantagonisten | |
| MA38161A1 (fr) | Anticorps anti-bmp-6 | |
| MA47221A1 (fr) | Anticorps monoclonal à pd-l1 | |
| ATE537153T1 (de) | Arylspirolactamverbindungen als antagonisten des cgrp-rezeptors | |
| MA31435B1 (fr) | Inhibition de metastases tumorales par des anticoprs anti-neuropiline 2 |