MA35064B1 - Dérivés de thiéno[2,3-d]pyrimidine et leur utilisation pour traiter l'arythmie - Google Patents

Dérivés de thiéno[2,3-d]pyrimidine et leur utilisation pour traiter l'arythmie

Info

Publication number
MA35064B1
MA35064B1 MA36364A MA36364A MA35064B1 MA 35064 B1 MA35064 B1 MA 35064B1 MA 36364 A MA36364 A MA 36364A MA 36364 A MA36364 A MA 36364A MA 35064 B1 MA35064 B1 MA 35064B1
Authority
MA
Morocco
Prior art keywords
thieno
pyrimidine derivatives
treating arrhythmia
arrhythmia
relates
Prior art date
Application number
MA36364A
Other languages
English (en)
Inventor
Derek Edward John
John Ford
Original Assignee
Xention Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44071904&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA35064(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Xention Ltd filed Critical Xention Ltd
Publication of MA35064B1 publication Critical patent/MA35064B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention concerne des composés thiénopyrimidine qui sont des inhibiteurs de canaux potassiques. Elle concerne également des compositions pharmaceutiques comprenant les composés et leur utilisation dans le traitement de l'arythmie.
MA36364A 2011-04-01 2012-03-29 Dérivés de thiéno[2,3-d]pyrimidine et leur utilisation pour traiter l'arythmie MA35064B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1105659.5A GB201105659D0 (en) 2011-04-01 2011-04-01 Compounds
PCT/GB2012/050710 WO2012131379A1 (fr) 2011-04-01 2012-03-29 Dérivés de thiéno[2,3-d]pyrimidine et leur utilisation pour traiter l'arythmie

Publications (1)

Publication Number Publication Date
MA35064B1 true MA35064B1 (fr) 2014-04-03

Family

ID=44071904

Family Applications (1)

Application Number Title Priority Date Filing Date
MA36364A MA35064B1 (fr) 2011-04-01 2012-03-29 Dérivés de thiéno[2,3-d]pyrimidine et leur utilisation pour traiter l'arythmie

Country Status (42)

Country Link
US (1) US9249155B2 (fr)
EP (1) EP2694518B1 (fr)
JP (1) JP5826374B2 (fr)
KR (1) KR20140023332A (fr)
CN (1) CN103492392B (fr)
AP (1) AP2013007198A0 (fr)
AR (1) AR088735A1 (fr)
AU (1) AU2012235882B2 (fr)
BR (1) BR112013025236A2 (fr)
CA (1) CA2831493A1 (fr)
CL (1) CL2013002789A1 (fr)
CO (1) CO6801756A2 (fr)
CR (1) CR20130488A (fr)
CU (1) CU24173B1 (fr)
CY (1) CY1117025T1 (fr)
DK (1) DK2694518T3 (fr)
EA (1) EA201301111A1 (fr)
EC (1) ECSP13012988A (fr)
ES (1) ES2558563T3 (fr)
GB (1) GB201105659D0 (fr)
GT (1) GT201300225A (fr)
HR (1) HRP20151340T1 (fr)
HU (1) HUE028438T2 (fr)
IL (1) IL228555A0 (fr)
MA (1) MA35064B1 (fr)
ME (1) ME02314B (fr)
MX (1) MX335937B (fr)
NI (1) NI201300100A (fr)
PE (1) PE20141021A1 (fr)
PH (1) PH12013501952A1 (fr)
PL (1) PL2694518T3 (fr)
PT (1) PT2694518E (fr)
RS (1) RS54458B1 (fr)
RU (1) RU2013148627A (fr)
SG (1) SG193578A1 (fr)
SI (1) SI2694518T1 (fr)
SM (1) SMT201500322B (fr)
TN (1) TN2013000377A1 (fr)
TW (1) TWI516265B (fr)
UA (1) UA110131C2 (fr)
WO (1) WO2012131379A1 (fr)
ZA (1) ZA201307085B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2922858A4 (fr) * 2012-11-20 2016-06-15 Univ Mcgill Inhibiteurs thiénopyrimidine de farnésyl et/ou de géranylgéranyl pyrophosphate synthase
SG11201804901WA (en) 2015-12-22 2018-07-30 SHY Therapeutics LLC Compounds for the treatment of cancer and inflammatory disease
CN106727587A (zh) * 2016-11-28 2017-05-31 李娜 一种治疗心律失常的药物组合物
EA201992780A1 (ru) 2017-06-21 2020-06-02 ШАЙ ТЕРАПЬЮТИКС ЭлЭлСи Соединения, которые взаимодействуют с суперсемейством ras, для лечения рака, воспалительных заболеваний, ras-опатий и фиброзного заболевания
US12391705B2 (en) 2018-12-19 2025-08-19 Shy Therapeutics, Llc Compounds that interact with the Ras superfamily for the treatment of cancers, inflammatory diseases, rasopathies, and fibrotic disease

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Also Published As

Publication number Publication date
CU24173B1 (es) 2016-04-25
TW201244720A (en) 2012-11-16
IL228555A0 (en) 2013-12-31
AU2012235882A1 (en) 2013-05-02
CN103492392A (zh) 2014-01-01
EA201301111A1 (ru) 2014-02-28
EP2694518B1 (fr) 2015-10-07
ME02314B (me) 2016-06-20
AR088735A1 (es) 2014-07-02
HK1193806A1 (zh) 2014-10-03
PE20141021A1 (es) 2014-08-30
GT201300225A (es) 2014-12-30
ES2558563T3 (es) 2016-02-05
MX335937B (es) 2016-01-04
DK2694518T3 (en) 2015-11-09
AU2012235882B2 (en) 2015-08-06
PH12013501952A1 (en) 2018-04-11
NI201300100A (es) 2014-01-07
AP2013007198A0 (en) 2013-10-31
EP2694518A1 (fr) 2014-02-12
CU20130124A7 (es) 2014-01-29
SG193578A1 (en) 2013-10-30
PL2694518T3 (pl) 2016-03-31
US20140206703A1 (en) 2014-07-24
NZ615621A (en) 2015-01-30
CO6801756A2 (es) 2013-11-29
CR20130488A (es) 2013-12-06
RU2013148627A (ru) 2015-05-10
TN2013000377A1 (en) 2015-01-20
HRP20151340T1 (hr) 2016-02-26
GB201105659D0 (en) 2011-05-18
JP2014509637A (ja) 2014-04-21
CY1117025T1 (el) 2017-04-05
HK1193096A1 (zh) 2014-09-12
CA2831493A1 (fr) 2012-10-04
CL2013002789A1 (es) 2014-07-18
HUE028438T2 (en) 2017-02-28
ZA201307085B (en) 2015-04-29
ECSP13012988A (es) 2013-12-31
KR20140023332A (ko) 2014-02-26
BR112013025236A2 (pt) 2019-09-24
CN103492392B (zh) 2015-11-25
SI2694518T1 (sl) 2016-02-29
TWI516265B (zh) 2016-01-11
JP5826374B2 (ja) 2015-12-02
UA110131C2 (ru) 2015-11-25
SMT201500322B (it) 2016-02-25
MX2013011301A (es) 2014-04-16
US9249155B2 (en) 2016-02-02
WO2012131379A1 (fr) 2012-10-04
PT2694518E (pt) 2016-02-05
RS54458B1 (sr) 2016-06-30

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