MA50438A - Promédicaments de dérivés de triazole substitués, et utilisations de ceux-ci - Google Patents

Promédicaments de dérivés de triazole substitués, et utilisations de ceux-ci

Info

Publication number
MA50438A
MA50438A MA050438A MA50438A MA50438A MA 50438 A MA50438 A MA 50438A MA 050438 A MA050438 A MA 050438A MA 50438 A MA50438 A MA 50438A MA 50438 A MA50438 A MA 50438A
Authority
MA
Morocco
Prior art keywords
triazole derivatives
substituted triazole
substituted
derivatives
triazole
Prior art date
Application number
MA050438A
Other languages
English (en)
Other versions
MA50438B1 (fr
Inventor
Anja Buchmueller
Hana Cernecka
Marie-Pierre Collin-Kroepelin
Karoline Droebner
Robert Fricke
Chantal Fuerstner
Peter Kolkhof
Ursula Krenz
Axel Kretschmer
Guillaume Levilain
Klemens Lustig
Thomas Mondritzki
Thomas Neubauer
Elisabeth Pook
Heiko Schirmer
Carsten Schmeck
Hanna Tinel
Pierre Wasnaire
Norbert Witowski
Matthias Beat Wittwer
Original Assignee
Bayer Ag
Bayer Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag, Bayer Pharma AG filed Critical Bayer Ag
Publication of MA50438A publication Critical patent/MA50438A/fr
Publication of MA50438B1 publication Critical patent/MA50438B1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MA50438A 2017-10-24 2018-10-17 Promédicaments de dérivés de triazole substitués, et utilisations de ceux-ci MA50438B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17197935 2017-10-24
PCT/EP2018/078364 WO2019081292A1 (fr) 2017-10-24 2018-10-17 Promédicaments de dérivés de triazole substitués, et utilisations de ceux-ci

Publications (2)

Publication Number Publication Date
MA50438A true MA50438A (fr) 2020-09-02
MA50438B1 MA50438B1 (fr) 2022-03-31

Family

ID=60162099

Family Applications (1)

Application Number Title Priority Date Filing Date
MA50438A MA50438B1 (fr) 2017-10-24 2018-10-17 Promédicaments de dérivés de triazole substitués, et utilisations de ceux-ci

Country Status (38)

Country Link
US (1) US11298367B2 (fr)
EP (1) EP3700913B1 (fr)
JP (1) JP2021500365A (fr)
KR (1) KR20200069361A (fr)
CN (1) CN111225921A (fr)
AR (1) AR113791A1 (fr)
AU (1) AU2018356352A1 (fr)
BR (1) BR112020007983A2 (fr)
CA (1) CA3079767A1 (fr)
CL (1) CL2020001076A1 (fr)
CO (1) CO2020004945A2 (fr)
CR (1) CR20200176A (fr)
CU (1) CU24604B1 (fr)
CY (1) CY1124938T1 (fr)
DK (1) DK3700913T3 (fr)
DO (1) DOP2020000076A (fr)
EA (1) EA202091025A1 (fr)
EC (1) ECSP20023056A (fr)
ES (1) ES2906305T3 (fr)
HR (1) HRP20220060T1 (fr)
HU (1) HUE057278T2 (fr)
IL (1) IL273949A (fr)
JO (1) JOP20200099A1 (fr)
LT (1) LT3700913T (fr)
MA (1) MA50438B1 (fr)
MX (1) MX2020004191A (fr)
NI (1) NI202000030A (fr)
PE (1) PE20210394A1 (fr)
PH (1) PH12020550473A1 (fr)
PL (1) PL3700913T3 (fr)
PT (1) PT3700913T (fr)
RS (1) RS62984B1 (fr)
SG (1) SG11202003049WA (fr)
SI (1) SI3700913T1 (fr)
TW (1) TW201932117A (fr)
UA (1) UA126456C2 (fr)
UY (1) UY37948A (fr)
WO (1) WO2019081292A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021259852A1 (fr) 2020-06-25 2021-12-30 Bayer Aktiengesellschaft Procédé de préparation de dérivés de 5-(alcoxycarbonyle)-et de 5- (carboxamide)-1-aryl-1,2,4-triazole
WO2022112213A1 (fr) 2020-11-30 2022-06-02 Bayer Aktiengesellschaft Formes cristallines de 3-[[3-(4-chlorophényl)-5-oxo-4-((2s)-3,3,3-trifluoro-2-hydroxypropyl)-4,5-dihydro-1h-1,2,4-triazol-1-yl]méthyl]-1-[3- (trifluorométhyl)pyridin-2-yl]-1h-1,2,4-triazole-5-carboxamide

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3966781A (en) 1970-12-17 1976-06-29 Merck Sharp & Dohme (I.A.) Corporation Deuteration of functional group-containing hydrocarbons
DE19834047A1 (de) 1998-07-29 2000-02-03 Bayer Ag Substituierte Pyrazolderivate
DE19834044A1 (de) 1998-07-29 2000-02-03 Bayer Ag Neue substituierte Pyrazolderivate
DE19943635A1 (de) 1999-09-13 2001-03-15 Bayer Ag Neuartige Aminodicarbonsäurederivate mit pharmazeutischen Eigenschaften
DE19943636A1 (de) 1999-09-13 2001-03-15 Bayer Ag Neuartige Dicarbonsäurederivate mit pharmazeutischen Eigenschaften
DE19943634A1 (de) 1999-09-13 2001-04-12 Bayer Ag Neuartige Dicarbonsäurederivate mit pharmazeutischen Eigenschaften
DE19943639A1 (de) 1999-09-13 2001-03-15 Bayer Ag Dicarbonsäurederivate mit neuartigen pharmazeutischen Eigenschaften
AR031176A1 (es) 2000-11-22 2003-09-10 Bayer Ag Nuevos derivados de pirazolpiridina sustituidos con piridina
DE10110750A1 (de) 2001-03-07 2002-09-12 Bayer Ag Neuartige Aminodicarbonsäurederivate mit pharmazeutischen Eigenschaften
DE10110749A1 (de) 2001-03-07 2002-09-12 Bayer Ag Substituierte Aminodicarbonsäurederivate
DE10220570A1 (de) 2002-05-08 2003-11-20 Bayer Ag Carbamat-substituierte Pyrazolopyridine
AP2331A (en) 2003-12-22 2011-12-05 Pfizer Triazole derivatives as vasopressin antagonists.
US20070225333A1 (en) 2004-04-28 2007-09-27 Bryans Justin S 3-Heterocyclyl-4-Phenyl-Triazole Derivatives as Inhibitors of the Vasopressin Via Receptor
JP2011502982A (ja) * 2007-11-06 2011-01-27 アストラゼネカ・アクチエボラーグ 好中球エラスターゼの阻害剤としてのある種の２−ピラジノン誘導体およびその使用
DE102010001064A1 (de) 2009-03-18 2010-09-23 Bayer Schering Pharma Aktiengesellschaft Substituierte 2-Acetamido-5-Aryl-1,2,4-triazolone und deren Verwendung
AR076542A1 (es) * 2009-05-22 2011-06-22 Merck Sharp & Dohme Antagonistas del receptor de orexina de isonicotinamida
CN103189363B (zh) 2010-02-27 2015-07-29 拜耳知识产权有限责任公司 双芳基连接的芳基三唑酮及其用途
DE102010021637A1 (de) 2010-05-26 2011-12-01 Bayer Schering Pharma Aktiengesellschaft Substituierte 5-Fluor-1H-Pyrazolopyridine und ihre Verwendung
PE20130779A1 (es) 2010-07-09 2013-06-21 Bayer Ip Gmbh Pirimidinas y triazinas condensadas y su uso
DE102010040233A1 (de) 2010-09-03 2012-03-08 Bayer Schering Pharma Aktiengesellschaft Bicyclische Aza-Heterocyclen und ihre Verwendung
DE102010043379A1 (de) 2010-11-04 2012-05-10 Bayer Schering Pharma Aktiengesellschaft Substituierte 6-Fluor-1H-Pyrazolo[4,3-b]pyridine und ihre Verwendung
US8791162B2 (en) 2011-02-14 2014-07-29 Merck Sharp & Dohme Corp. Cathepsin cysteine protease inhibitors
WO2015055707A1 (fr) * 2013-10-16 2015-04-23 Bayer Cropscience Ag Associations de composés actifs comprenant un dérivé de (thio)carboximide et un composé fongicide
PE20170945A1 (es) 2014-11-03 2017-07-13 Bayer Pharma AG Derivados de feniltriazol sustituido con hidroxialquilo y sus usos
UY36571A (es) * 2015-03-05 2016-09-30 Bayer Cropscience Ag Combinaciones de compuestos activos
WO2017191105A1 (fr) 2016-05-03 2017-11-09 Bayer Pharma Aktiengesellschaft Dérivés d'aryltriazole à substitution amide et leurs utilisations
WO2017191114A1 (fr) 2016-05-03 2017-11-09 Bayer Aktiengesellschaft Dérivés d'hétéroaryltriazole substitués par hydroxyalkyle et utilisations associées
CA3022755A1 (fr) 2016-05-03 2017-11-09 Carsten Schmeck Derives de phenyltriazole a substitution oxoalkyle et utilisations associees
US10525041B2 (en) 2016-05-03 2020-01-07 Bayer Pharma Aktiengesellschaft Fluoroalkyl-substituted aryltriazole derivatives and uses thereof
US10815205B2 (en) 2016-05-03 2020-10-27 Bayer Pharma Aktiengesellschaft Amide-substituted phenyltriazole derivatives and uses thereof
US9988367B2 (en) 2016-05-03 2018-06-05 Bayer Pharma Aktiengesellschaft Amide-substituted pyridinyltriazole derivatives and uses thereof
US10927098B2 (en) 2016-10-20 2021-02-23 Bayer Pharma Aktiengesellschaft Hydroxyalkyl-substituted triazole derivatives and uses thereof

Also Published As

Publication number Publication date
CL2020001076A1 (es) 2021-02-19
US11298367B2 (en) 2022-04-12
NI202000030A (es) 2020-10-09
MA50438B1 (fr) 2022-03-31
RS62984B1 (sr) 2022-03-31
BR112020007983A2 (pt) 2020-10-27
IL273949A (en) 2020-05-31
JP2021500365A (ja) 2021-01-07
ES2906305T3 (es) 2022-04-18
UA126456C2 (uk) 2022-10-05
WO2019081292A1 (fr) 2019-05-02
US20200338096A1 (en) 2020-10-29
CY1124938T1 (el) 2023-01-05
MX2020004191A (es) 2020-08-03
UY37948A (es) 2019-05-31
EP3700913A1 (fr) 2020-09-02
EP3700913B1 (fr) 2021-11-10
CU20200040A7 (es) 2021-03-11
PE20210394A1 (es) 2021-03-02
SG11202003049WA (en) 2020-04-29
CN111225921A (zh) 2020-06-02
CO2020004945A2 (es) 2020-05-05
ECSP20023056A (es) 2020-12-31
SI3700913T1 (sl) 2022-02-28
CU24604B1 (es) 2022-06-06
PT3700913T (pt) 2022-01-31
HRP20220060T1 (hr) 2022-04-15
PL3700913T3 (pl) 2022-02-21
PH12020550473A1 (en) 2021-03-08
AR113791A1 (es) 2020-06-10
TW201932117A (zh) 2019-08-16
EA202091025A1 (ru) 2020-07-30
HUE057278T2 (hu) 2022-04-28
LT3700913T (lt) 2022-01-25
JOP20200099A1 (ar) 2020-05-06
DK3700913T3 (da) 2022-02-07
KR20200069361A (ko) 2020-06-16
AU2018356352A1 (en) 2020-04-16
CR20200176A (es) 2020-07-24
DOP2020000076A (es) 2020-08-31
CA3079767A1 (fr) 2019-05-02

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