MA53108A - Utilisation de prg4 comme agent anti-inflammatoire - Google Patents

Utilisation de prg4 comme agent anti-inflammatoire

Info

Publication number
MA53108A
MA53108A MA053108A MA53108A MA53108A MA 53108 A MA53108 A MA 53108A MA 053108 A MA053108 A MA 053108A MA 53108 A MA53108 A MA 53108A MA 53108 A MA53108 A MA 53108A
Authority
MA
Morocco
Prior art keywords
prg4
inflammatory agent
inflammatory
agent
Prior art date
Application number
MA053108A
Other languages
English (en)
Inventor
Khaled Elsaid
Jawed Fareed
Gregory D Jay
Roman Krawetz
Tannin Avery Schmidt
Benjamin D Sullivan
Edward R Truitt
Original Assignee
Lubris Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lubris Llc filed Critical Lubris Llc
Publication of MA53108A publication Critical patent/MA53108A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P17/00—Drugs for dermatological disorders
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
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    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Psychiatry (AREA)
  • Virology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
MA053108A 2015-01-26 2016-01-26 Utilisation de prg4 comme agent anti-inflammatoire MA53108A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562107799P 2015-01-26 2015-01-26
US201562273059P 2015-12-30 2015-12-30

Publications (1)

Publication Number Publication Date
MA53108A true MA53108A (fr) 2021-05-12

Family

ID=55361962

Family Applications (1)

Application Number Title Priority Date Filing Date
MA053108A MA53108A (fr) 2015-01-26 2016-01-26 Utilisation de prg4 comme agent anti-inflammatoire

Country Status (19)

Country Link
US (2) US10967048B2 (fr)
EP (2) EP3718559B1 (fr)
JP (2) JP6758299B2 (fr)
KR (1) KR20170123619A (fr)
CN (2) CN107847556B (fr)
AU (2) AU2016211694B2 (fr)
BR (1) BR112017015310A8 (fr)
CL (2) CL2017001893A1 (fr)
EA (1) EA036291B1 (fr)
ES (2) ES2808199T3 (fr)
IL (2) IL253596B (fr)
MA (1) MA53108A (fr)
MX (1) MX2017009723A (fr)
PH (1) PH12017501323A1 (fr)
RU (1) RU2017129880A (fr)
SG (2) SG11201705636SA (fr)
TN (1) TN2017000270A1 (fr)
WO (1) WO2016123123A1 (fr)
ZA (1) ZA201705378B (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015060935A1 (fr) 2013-10-22 2015-04-30 Lubris, Llc Régulation des propriétés rhéologiques de solutions de hyaluronate/lubricine mélangées
EP4062924A1 (fr) 2013-11-26 2022-09-28 Lubris LLC Compositions et procédés pour inhiber les interactions intercellulaires
RU2017129880A (ru) 2015-01-26 2019-03-04 ЛУБРИС ЭлЭлСи Применение prg4 в качестве противовоспалительного средства
HK1251130A1 (zh) 2015-05-01 2019-01-25 Gentex Corporation 头盔冲击衰减物品
JP7291459B2 (ja) 2015-05-19 2023-06-15 ルブリス，エルエルシー． 動体視力および高次収差を改善するためのｐｒｇ４の使用
CN106215170A (zh) * 2016-08-23 2016-12-14 重庆医科大学 白细胞介素36α在制备治疗、诊断或预防脓毒症药物中的用途
US10813761B2 (en) 2017-05-23 2020-10-27 Harmony Development Group, Inc. Tethered implantable device having a vortical intracardiac velocity adjusting balloon
US10940002B2 (en) 2017-06-28 2021-03-09 Harmony Development Group, Inc. Force transducting inflatable implant system including a dual force annular transduction implant
US11167122B2 (en) 2018-03-05 2021-11-09 Harmony Development Group, Inc. Force transducting implant system for the mitigation of atrioventricular pressure gradient loss and the restoration of healthy ventricular geometry
CN108795867A (zh) * 2018-06-05 2018-11-13 华东理工大学 用于构建结肠癌细胞腹膜转移体外三维模型的方法
MX2020013869A (es) * 2018-06-21 2021-03-02 Lubris Llc Lubricina para uso en curacion de heridas referencia cruzada con solicitudes relacionadas.
CN109125709B (zh) * 2018-08-23 2021-10-22 成都华创生物技术有限公司 Trail突变体在制备治疗痤疮药物中的应用及一种制剂
US12285182B2 (en) 2018-10-10 2025-04-29 Innova Vascular, Inc. Devices and methods for removing an embolus
CN109620952A (zh) * 2019-01-04 2019-04-16 北京中台恒基生物技术有限公司 一种肿瘤疫苗及其制备方法
CN113573724B (zh) * 2019-01-15 2025-12-19 康奈尔大学 重组润滑素和组合物以及其使用方法
EP3976085A4 (fr) * 2019-06-03 2023-04-05 Lubris LLC Utilisation de prg4 pour traiter le cancer
WO2022010996A1 (fr) * 2020-07-07 2022-01-13 University Of Connecticut Méthode et composition pour réduire ou prévenir la résorption osseuse
IT202000022636A1 (it) * 2020-09-25 2022-03-25 Ente Ospedaliero Specializzato In Gastroenterologia Istituto Nazionale Di Ricovero E Cura A Caratter “terapia di combinazione di sorafenib e/o regorafenib con la proteina ricombinante umana proteoglicano-4 per il trattamento dell'epatocarcinoma”
JP2022070061A (ja) * 2020-10-26 2022-05-12 サンスター株式会社 外用組成物
CN114184792B (zh) * 2021-11-17 2024-05-28 中国人民解放军总医院第二医学中心 冠心病标志物il-29及其应用
KR102882547B1 (ko) * 2022-05-16 2025-11-05 중앙대학교 산학협력단 인터루킨 1 베타 검출용 신규한 펩타이드

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6433142B1 (en) 1989-08-08 2002-08-13 Genetics Institute, Llc Megakaryocyte stimulating factors
US6960562B2 (en) 1999-04-23 2005-11-01 Rhode Island Hospital, A Lifespan Partner Tribonectin polypeptides and uses thereof
US6743774B1 (en) 1999-04-23 2004-06-01 Rhode Island Hospital Tribonectins
US7001881B1 (en) 1999-04-23 2006-02-21 Rhode Island Hospital Tribonectins
US20020006665A1 (en) 2000-04-05 2002-01-17 D'elia John Ketogulonigenium endogenous plasmids
US7415381B2 (en) 2003-01-09 2008-08-19 Rhode Island Hospital, A Lifespan Partner Joint friction sensing
US20060240037A1 (en) 2003-06-04 2006-10-26 Edward Fey Methods and compositions for the treatment and prevention of degenerative joint disorders
UA91818C2 (ru) * 2003-08-14 2010-09-10 Уайт Рекомбинантные молекулы лубрицина и их использование
WO2005102363A2 (fr) 2004-04-20 2005-11-03 Mucosal Therapeutics Llc Methodes destinees a favoriser la cicatrisation du cartilage ou l'integration du cartilage
WO2006012492A2 (fr) 2004-07-23 2006-02-02 Mucosal Therapeutics Llc Compositions et procedes de viscosupplementation
WO2006060473A2 (fr) * 2004-12-03 2006-06-08 Mucosal Therapeutics Llc Methodes de traitement d'articulations lesees ou malades
US20070111327A1 (en) 2005-05-05 2007-05-17 Jay Gregory D Methods of detecting lubricin
CN101077887A (zh) * 2006-05-23 2007-11-28 中国医学科学院血液学研究所 人促造血细胞增殖的细胞因子及其制备方法和用途
UY30776A1 (es) 2006-12-21 2008-07-03 Medarex Inc Anticuerpos cd44
WO2008143816A1 (fr) 2007-05-15 2008-11-27 Mucosal Therapeutics Compositions et procédés pour la réduction de la friction entre la surface des tendons et d'autres tissus mous
US20090068247A1 (en) 2007-09-12 2009-03-12 Mucosal Therapeutics Biocompatible devices coated with a tribonectin and methods for their production
US20090104148A1 (en) 2007-09-18 2009-04-23 Jay Gregory D Treatment and prevention of joint disease
US20090191287A1 (en) 2008-01-29 2009-07-30 Johnson W Dudley Mitigation of Inflammation-Related Injuries
CN105664136A (zh) * 2008-05-07 2016-06-15 加利福尼亚大学董事会 眼表润滑的治疗性补充和富集
US8506944B2 (en) 2008-05-07 2013-08-13 The Regents Of The University Of California Replenishment and enrichment of ocular surface lubrication
EP2381957B1 (fr) * 2009-01-13 2015-01-07 Lubris LLC Modulation thérapeutique de la lubrification limite de l'épithélium vaginal
CA3110817C (fr) * 2009-05-22 2023-08-15 Lubris, Llc Application et utilisation de prg4 et modulation therapeutique connexe
US9107885B2 (en) 2009-08-13 2015-08-18 Lubris Llc PRG4 treatment for interstitial cystitis
ES2627103T3 (es) 2010-01-19 2017-07-26 Lubris Llc Composiciones de cuidado bucal y métodos
US20130116186A1 (en) 2011-10-04 2013-05-09 Rhode Island Hospital, A Lifespan Partner Lubricin injections to maintain cartilage health
PL2948553T3 (pl) 2013-01-25 2020-11-16 Baylor College Of Medicine Adenowirusowy system dostarczania i ekspresji terapii genowej zależny od pomocnika
WO2015060935A1 (fr) 2013-10-22 2015-04-30 Lubris, Llc Régulation des propriétés rhéologiques de solutions de hyaluronate/lubricine mélangées
EP4062924A1 (fr) 2013-11-26 2022-09-28 Lubris LLC Compositions et procédés pour inhiber les interactions intercellulaires
RU2017129880A (ru) 2015-01-26 2019-03-04 ЛУБРИС ЭлЭлСи Применение prg4 в качестве противовоспалительного средства
US20180161393A1 (en) 2015-01-26 2018-06-14 Lubris Llc Prg4 for treating gout and its symptoms
JP7291459B2 (ja) 2015-05-19 2023-06-15 ルブリス，エルエルシー． 動体視力および高次収差を改善するためのｐｒｇ４の使用
US20170312335A1 (en) 2015-12-30 2017-11-02 Lubris Llc Topical use of prg4 for treatment of allergy and symptoms of inflammation

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MX2017009723A (es) 2018-08-15
US11717557B2 (en) 2023-08-08
CN107847556B (zh) 2021-09-24
AU2016211694B2 (en) 2021-11-11
CL2018003302A1 (es) 2019-01-04
BR112017015310A8 (pt) 2021-02-23
US20180015141A1 (en) 2018-01-18
ES3014621T3 (en) 2025-04-23
IL285553A (en) 2021-09-30
JP6758299B2 (ja) 2020-09-23
JP2018505867A (ja) 2018-03-01
AU2016211694A1 (en) 2017-08-31
SG11201705636SA (en) 2017-08-30
KR20170123619A (ko) 2017-11-08
US10967048B2 (en) 2021-04-06
WO2016123123A1 (fr) 2016-08-04
RU2017129880A (ru) 2019-03-04
JP2020189878A (ja) 2020-11-26
CN113908257A (zh) 2022-01-11
EA201791688A8 (ru) 2018-05-31
SG10201809947UA (en) 2018-12-28
AU2022200812A1 (en) 2022-02-24
EA201791688A1 (ru) 2018-01-31
EA036291B1 (ru) 2020-10-22
EP3718559A1 (fr) 2020-10-07
PH12017501323A1 (en) 2018-02-05
ES2808199T3 (es) 2021-02-25
IL253596A0 (en) 2017-09-28
JP7212653B2 (ja) 2023-01-25
IL253596B (en) 2021-08-31
EP3250221B1 (fr) 2020-05-27
BR112017015310A2 (pt) 2018-01-16
RU2017129880A3 (fr) 2019-08-22
EP3250221A1 (fr) 2017-12-06
CA2972817A1 (fr) 2016-08-04
US20210299214A1 (en) 2021-09-30
TN2017000270A1 (en) 2018-10-19
HK1247834A1 (en) 2018-10-05
CN107847556A (zh) 2018-03-27
EP3718559B1 (fr) 2024-12-04
ZA201705378B (en) 2020-11-25
CL2017001893A1 (es) 2018-06-15

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