MA54568A - Substitutions de nucléotides prédéterminées - Google Patents

Substitutions de nucléotides prédéterminées

Info

Publication number
MA54568A
MA54568A MA054568A MA54568A MA54568A MA 54568 A MA54568 A MA 54568A MA 054568 A MA054568 A MA 054568A MA 54568 A MA54568 A MA 54568A MA 54568 A MA54568 A MA 54568A
Authority
MA
Morocco
Prior art keywords
nucleotide substitutions
predetermined nucleotide
predetermined
substitutions
nucleotide
Prior art date
Application number
MA054568A
Other languages
English (en)
Inventor
Massimiliano Carciofi
Søren Knudsen
Ole Olsen
Birgitte Skadhauge
Alexander Striebeck
Hanne Cecilie Thomsen
Toni Wendt
Rasmussen Magnus Wohlfahrt
Original Assignee
Carlsberg As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Carlsberg As filed Critical Carlsberg As
Publication of MA54568A publication Critical patent/MA54568A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/6895—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H4/00—Plant reproduction by tissue culture techniques ; Tissue culture techniques therefor
    • A01H4/005—Methods for micropropagation; Vegetative plant propagation using cell or tissue culture techniques
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H6/00—Angiosperms, i.e. flowering plants, characterised by their botanic taxonomy
    • A01H6/46—Gramineae or Poaceae, e.g. ryegrass, rice, wheat or maize
    • A01H6/4624—Hordeum vulgarus [barley]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/01—Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102—Mutagenizing nucleic acids
    • C12N15/1024—In vivo mutagenesis using high mutation rate "mutator" host strains by inserting genetic material, e.g. encoding an error prone polymerase, disrupting a gene for mismatch repair
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00—Methods of screening libraries
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/13—Plant traits
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Botany (AREA)
  • Environmental Sciences (AREA)
  • Physiology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
MA054568A 2016-07-01 2017-06-23 Substitutions de nucléotides prédéterminées MA54568A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA201670485 2016-07-01

Publications (1)

Publication Number Publication Date
MA54568A true MA54568A (fr) 2021-10-27

Family

ID=56681913

Family Applications (3)

Application Number Title Priority Date Filing Date
MA052594A MA52594A (fr) 2016-07-01 2017-06-23 Procédé d'identification d'un sous-ensemble comprenant un organisme mutant
MA054568A MA54568A (fr) 2016-07-01 2017-06-23 Substitutions de nucléotides prédéterminées
MA045531A MA45531A (fr) 2016-07-01 2017-06-23 Procédé de criblage d'un mutant dans une population d'organismes par application d'une approche de regroupement et de division

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MA052594A MA52594A (fr) 2016-07-01 2017-06-23 Procédé d'identification d'un sous-ensemble comprenant un organisme mutant

Family Applications After (1)

Application Number Title Priority Date Filing Date
MA045531A MA45531A (fr) 2016-07-01 2017-06-23 Procédé de criblage d'un mutant dans une population d'organismes par application d'une approche de regroupement et de division

Country Status (25)

Country Link
US (2) US11884972B2 (fr)
EP (3) EP3478832B1 (fr)
JP (2) JP7208797B2 (fr)
CN (2) CN114959098A (fr)
AR (1) AR110103A1 (fr)
AU (3) AU2017288960B2 (fr)
BR (1) BR112018076429A2 (fr)
CA (1) CA3026016A1 (fr)
CL (1) CL2018003710A1 (fr)
CO (1) CO2019000828A2 (fr)
CR (1) CR20190040A (fr)
CU (1) CU20180158A7 (fr)
DK (1) DK3478832T3 (fr)
EA (1) EA201892809A1 (fr)
ES (2) ES2916221T3 (fr)
IL (1) IL263451B (fr)
MA (3) MA52594A (fr)
MX (2) MX2018016110A (fr)
PE (1) PE20190228A1 (fr)
PL (2) PL3792357T3 (fr)
PT (1) PT3478832T (fr)
SG (1) SG11201811021YA (fr)
UY (1) UY37312A (fr)
WO (1) WO2018001884A1 (fr)
ZA (3) ZA201808218B (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7208797B2 (ja) * 2016-07-01 2023-01-19 カールスバーグ エー／エス プーリング及び分割アプローチを適用することによって生物の集団内の突然変異体をスクリーニングする方法
WO2019129736A1 (fr) 2017-12-28 2019-07-04 Carlsberg A/S Plantes céréalières présentant des propriétés de paroi cellulaire améliorées
CA3106307A1 (fr) * 2018-07-13 2020-01-16 Hifibio Sas Utilisation d'un profilage epigenetique de cellules uniques de gouttelettes pour la stratification de patients
WO2020011998A1 (fr) * 2018-07-13 2020-01-16 Hifibio Sas Utilisation d'un profilage d'épigénome monocellulaire de gouttelettes pour la stratification de patients
CN108913698B (zh) * 2018-07-25 2021-10-26 安徽农业大学 一种与小麦穗发芽抗性/感性相关的caps标记及其应用
CN110724741B (zh) * 2019-07-24 2020-05-19 艾普拜生物科技(苏州)有限公司 一种检测微小残留白血病相关融合基因的引物、探针及其试剂盒
EP4013843A1 (fr) * 2019-08-16 2022-06-22 Heineken Supply Chain B.V. Production d'une boisson sans alcool
EP3785529A1 (fr) 2019-08-28 2021-03-03 Carlsberg A/S Plantes d'orge avec une teneur en protéine modifiéé dans les graines
EP4040946A1 (fr) * 2019-10-10 2022-08-17 Carlsberg A/S Procédés de préparation de compositions de plantes mutantes
US20240043911A1 (en) * 2020-02-06 2024-02-08 The Administrators Of The Tulane Educational Fund Crispr-based assay for detecting tb in bodily fluids
MX2022010777A (es) 2020-03-02 2022-11-30 Carlsberg As Plantas de cebada con elevada actividad de dextrinasa limite.
EP4029935A1 (fr) 2021-01-14 2022-07-20 Carlsberg A/S Souche de s. eubayanus et ses hybrides
CA3234121A1 (fr) * 2021-10-25 2023-05-04 Sarah KANE Sequences de blocage hors cible pour ameliorer la distinction de la cible par reaction en chaine de la polymerase
CA3240580A1 (fr) 2021-12-22 2023-06-29 Timothy James Golds Procede de criblage ameliore pour des evenements edites sur le genome
AU2023231447A1 (en) 2022-03-11 2024-09-05 Carlsberg A/S Modulation of protein levels
CN120225050A (zh) 2022-11-16 2025-06-27 哥本哈根大学 种子硫代葡萄糖苷含量低的植物
WO2024133900A1 (fr) 2022-12-22 2024-06-27 University Of Copenhagen Production de (-)-spartéine améliorée
AU2024265403A1 (en) 2023-05-01 2025-10-16 Carlsberg A/S Barley with improved properties
WO2025108936A1 (fr) * 2023-11-20 2025-05-30 Eth Zurich Procédé de fourniture de cellules génétiquement modifiées
CN117965576B (zh) * 2024-02-01 2024-08-27 北京林业大学 一种王百合苷生物合成基因LlHCT1及其应用
EP4644572A1 (fr) * 2024-04-29 2025-11-05 KWS SAAT SE & Co. KGaA Procédé d'analyse de pureté de caractères dans des grands volumes de semences
WO2025240938A2 (fr) * 2024-05-16 2025-11-20 Oath, Inc. Production de consortiums microbiens
WO2026037962A1 (fr) 2024-08-15 2026-02-19 University Of Copenhagen Légumineuses ou parties de celles-ci à teneur réduite en alcaloïdes de quinolizidine

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US4351760A (en) 1979-09-07 1982-09-28 Syva Company Novel alkyl substituted fluorescent compounds and polyamino acid conjugates
US5188934A (en) 1989-11-14 1993-02-23 Applied Biosystems, Inc. 4,7-dichlorofluorescein dyes as molecular probes
WO1998023759A2 (fr) 1996-11-26 1998-06-04 Baylor College Of Medicine Identification d'inhibiteurs empechant l'acces de la telomerase aux terminaisons chromosomiques
CA2288988A1 (fr) 1997-06-04 1998-12-10 Smithkline Beecham Corporation Methodes de clonage rapide d'adnc de longueur totale
US6484105B2 (en) 1998-04-02 2002-11-19 Maxyag, Inc. Method for obtaining a plant with a genetic lesion in a gene sequence
GB9812768D0 (en) 1998-06-13 1998-08-12 Zeneca Ltd Methods
US20050177901A1 (en) * 2001-06-22 2005-08-11 Syngenta Participations Ag Identification and characterization of plant genes
GB0127564D0 (en) 2001-11-16 2002-01-09 Medical Res Council Emulsion compositions
US7420105B2 (en) 2004-03-11 2008-09-02 Carlsberg A/S Barley for production of flavor-stable beverage
CN102405402A (zh) 2008-09-23 2012-04-04 阔达生命有限公司 基于液滴的测定系统
US9005565B2 (en) 2010-06-24 2015-04-14 Hamid-Reza Jahangiri-Famenini Method and apparatus for forming graphene
WO2012122571A1 (fr) * 2011-03-10 2012-09-13 Gen-Probe Incorporated Procédés et compositions de sélection et d'optimisation de séquences de marquage oligonucléotidiques
CA2831180C (fr) 2011-04-11 2017-02-14 Keith Bauer Adn polymerases avec une activite amelioree
WO2015131101A1 (fr) 2014-02-27 2015-09-03 Monsanto Technology Llc Compositions et procédés de modification génomique dirigée
GB201411603D0 (en) * 2014-06-30 2014-08-13 Vela Operations Pte Ltd Compositions for quantitative and/or semiquantitative mutation detection methods
JP7208797B2 (ja) * 2016-07-01 2023-01-19 カールスバーグ エー／エス プーリング及び分割アプローチを適用することによって生物の集団内の突然変異体をスクリーニングする方法
EP4040946A1 (fr) * 2019-10-10 2022-08-17 Carlsberg A/S Procédés de préparation de compositions de plantes mutantes

Also Published As

Publication number Publication date
DK3478832T3 (da) 2022-05-30
CN109477087A (zh) 2019-03-15
IL263451B (en) 2022-08-01
WO2018001884A1 (fr) 2018-01-04
EP3693458A1 (fr) 2020-08-12
AU2019268102A1 (en) 2019-12-12
JP7208797B2 (ja) 2023-01-19
US12428678B2 (en) 2025-09-30
PT3478832T (pt) 2022-05-19
ZA201907775B (en) 2022-09-28
AR110103A1 (es) 2019-02-27
MA52594A (fr) 2021-03-17
US20190194723A1 (en) 2019-06-27
JP2019524083A (ja) 2019-09-05
AU2017288960B2 (en) 2019-12-12
CL2018003710A1 (es) 2019-03-22
EP3792357B1 (fr) 2025-05-07
ZA201907774B (en) 2022-07-27
NZ749382A (en) 2025-06-27
CU20180158A7 (es) 2019-08-06
US11884972B2 (en) 2024-01-30
US20240182961A1 (en) 2024-06-06
ES2916221T3 (es) 2022-06-29
CR20190040A (es) 2019-05-09
CN114959098A (zh) 2022-08-30
CO2019000828A2 (es) 2019-04-30
JP2022101703A (ja) 2022-07-06
PL3478832T3 (pl) 2022-06-06
EP3792357A1 (fr) 2021-03-17
AU2019268103A1 (en) 2019-12-12
MX2022014965A (es) 2023-01-11
AU2019268103B2 (en) 2020-03-12
MX2018016110A (es) 2019-05-30
PL3792357T3 (pl) 2025-07-07
JP7539428B2 (ja) 2024-08-23
ZA201808218B (en) 2020-02-26
BR112018076429A2 (pt) 2019-10-01
SG11201811021YA (en) 2019-01-30
PE20190228A1 (es) 2019-02-13
EP3478832A1 (fr) 2019-05-08
IL263451A (en) 2019-01-31
EA201892809A1 (ru) 2019-06-28
CN109477087B (zh) 2022-06-24
EP3478832B1 (fr) 2022-02-23
ES3032697T3 (en) 2025-07-23
AU2019268102B2 (en) 2020-03-05
AU2017288960A1 (en) 2019-01-17
UY37312A (es) 2018-02-28
CA3026016A1 (fr) 2018-01-04
EP3792357C0 (fr) 2025-05-07
MA45531A (fr) 2019-05-08

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