MC2131A1 - Nouveaux derives de peptides intestinaux vasoactifs - Google Patents

Nouveaux derives de peptides intestinaux vasoactifs

Info

Publication number
MC2131A1
MC2131A1 MC902134A MC2134A MC2131A1 MC 2131 A1 MC2131 A1 MC 2131A1 MC 902134 A MC902134 A MC 902134A MC 2134 A MC2134 A MC 2134A MC 2131 A1 MC2131 A1 MC 2131A1
Authority
MC
Monaco
Prior art keywords
ala
boc
mmol
lys
thr
Prior art date
Application number
MC902134A
Other languages
English (en)
French (fr)
Inventor
Robert Bolin David
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MC2131A1 publication Critical patent/MC2131A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57563—Vasoactive intestinal peptide [VIP]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/17—Vasoactive intestinal peptides; related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MC902134A 1989-06-30 1990-06-28 Nouveaux derives de peptides intestinaux vasoactifs MC2131A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/374,503 US5141924A (en) 1989-06-30 1989-06-30 Synthetic vasoactive intestinal peptide analogs

Publications (1)

Publication Number Publication Date
MC2131A1 true MC2131A1 (fr) 1992-01-03

Family

ID=23477126

Family Applications (1)

Application Number Title Priority Date Filing Date
MC902134A MC2131A1 (fr) 1989-06-30 1990-06-28 Nouveaux derives de peptides intestinaux vasoactifs

Country Status (16)

Country Link
US (1) US5141924A (de)
EP (1) EP0405242A3 (de)
JP (1) JPH0338600A (de)
KR (1) KR910000794A (de)
AU (1) AU5808490A (de)
CA (1) CA2019970A1 (de)
FI (1) FI903296A7 (de)
HU (1) HUT55803A (de)
IE (1) IE902388A1 (de)
IL (1) IL94884A0 (de)
MC (1) MC2131A1 (de)
NO (1) NO902916L (de)
NZ (1) NZ234268A (de)
PT (1) PT94553A (de)
YU (1) YU126690A (de)
ZA (1) ZA904897B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03181499A (ja) * 1989-12-11 1991-08-07 Akira Kaji 新規ペプチド
AU656230B2 (en) * 1991-10-11 1995-01-27 F. Hoffmann-La Roche Ag Cyclic vasoactive peptides
JPH06220090A (ja) * 1993-01-22 1994-08-09 Sanwa Kagaku Kenkyusho Co Ltd ポリペプチド
US6489297B1 (en) 2000-02-18 2002-12-03 Dabur Research Foundation Vasoactive intestinal peptide analogs
EP1257575B1 (de) 2000-02-18 2007-02-28 Dabur Research Foundation Radiomarkierte vip-analoge zur diagnose und therapie
US6828304B1 (en) 2000-07-31 2004-12-07 Dabur Research Foundation Peptides for treatment of cancer
US20040063631A1 (en) 2000-11-28 2004-04-01 Lutz-Henning Block Compounds with the biological activity of vasoactive intestinal peptide for the treatment of pulmonary and arteriolar hypertension
US6933404B2 (en) * 2001-12-18 2005-08-23 Metabolix Inc. Methods of making intermediates from polyhydroxyalkanoates
HK1080363B (zh) 2002-06-10 2007-12-21 Mondobiotech Ag 具有血管活性肠肽的生物学活性的化合物在治疗结节病中的用途
JP4477506B2 (ja) * 2002-11-27 2010-06-09 Ｉｌｓ株式会社 ペプチド及びこれを含む医薬組成物
PL3311828T3 (pl) 2009-08-14 2021-11-22 Phasebio Pharmaceuticals, Inc. Zmodyfikowane wazoaktywne peptydy jelitowe
WO2011100601A1 (en) 2010-02-11 2011-08-18 Metabolix, Inc. Process for gamma-butyrolactone production
CA2873553C (en) 2011-06-06 2020-01-28 Phasebio Pharmaceuticals, Inc. Use of modified vasoactive intestinal peptides in the treatment of hypertension
CA2976038A1 (en) 2015-02-09 2016-08-18 Phasebio Pharmaceuticals, Inc. Methods and compositions for treating muscle disease and disorders

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4734400A (en) * 1984-10-09 1988-03-29 Hoffmann-La Roche Inc. Synthetic vasoactive intestinal peptide analogs
US4605641A (en) * 1984-10-09 1986-08-12 Hoffmann-La Roche Inc. Synthetic vasoactive intestinal peptide analogs
GB8427651D0 (en) * 1984-11-01 1984-12-05 Beecham Group Plc Compounds
JPS62246595A (ja) * 1986-04-17 1987-10-27 Eisai Co Ltd 気菅支拡張作用・降圧作用ペプタイド
US4835252A (en) * 1987-02-26 1989-05-30 The Salk Institute Biotechnology/Industrial Associates, Inc. Vasoactive intestinal peptide analogs
US4939224A (en) * 1987-02-26 1990-07-03 The Salk Institute Biotechnology/Industrial Associates, Inc. Vasoactive intestinal peptide analogs
SE8702520D0 (sv) * 1987-06-16 1987-06-16 Kabigen Ab Mammal intestine hormone precursor
SE8705139D0 (sv) * 1987-12-23 1987-12-23 Trion Forskning & Utveckling Forfarande for framstellning av ett stort antal peptidanaloger och nya peptidanaloger

Also Published As

Publication number Publication date
JPH0338600A (ja) 1991-02-19
FI903296A7 (fi) 1990-12-31
US5141924A (en) 1992-08-25
HUT55803A (en) 1991-06-28
NO902916L (no) 1991-01-02
YU126690A (sh) 1993-05-28
NZ234268A (en) 1992-11-25
EP0405242A2 (de) 1991-01-02
PT94553A (pt) 1991-02-08
KR910000794A (ko) 1991-01-30
ZA904897B (en) 1991-03-27
AU5808490A (en) 1991-01-03
HU904033D0 (en) 1990-12-28
EP0405242A3 (en) 1992-05-27
IE902388A1 (en) 1991-06-19
CA2019970A1 (en) 1990-12-31
IE902388L (en) 1990-12-30
FI903296A0 (fi) 1990-06-29
NO902916D0 (no) 1990-06-29
IL94884A0 (en) 1991-04-15

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