ME00563A - Process for preparing optically pure active compounds - Google Patents

Process for preparing optically pure active compounds

Info

Publication number: ME00563A
Authority: ME; Montenegro
Prior art keywords: optically pure; active compounds; pure active; preparing optically; chiral
Prior art date: 2002-12-06

Application number

MEP-848/08A

Other languages

Bosnian (bs)

English (en)

Inventor

Bernhard Kohl

Bernd Mueller

Ralf Steffen Weingart

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-12-06

Filing date

2003-12-03

Publication date

2011-12-20

2003-12-03 Application filed filed Critical

2011-12-20 Publication of ME00563A publication Critical patent/ME00563A/xx

Links

150000001875 compounds Chemical class 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
QCWXUUIWCKQGHC-UHFFFAOYSA-N Zirconium Chemical compound [Zr] QCWXUUIWCKQGHC-UHFFFAOYSA-N 0.000 abstract 1
229910052735 hafnium Inorganic materials 0.000 abstract 1
VBJZVLUMGGDVMO-UHFFFAOYSA-N hafnium atom Chemical compound [Hf] VBJZVLUMGGDVMO-UHFFFAOYSA-N 0.000 abstract 1
229910052726 zirconium Inorganic materials 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Plural Heterocyclic Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pyrrole Compounds (AREA)
Catalysts (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Pyridine Compounds (AREA)

MEP-848/08A 2002-12-06 2003-12-03 Process for preparing optically pure active compounds ME00563A (en)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
EP02027273		2002-12-06
DE10340255		2003-08-29
PCT/EP2003/013605 WO2004052882A1 (en)	2002-12-06	2003-12-03	Process for preparing optically pure active compounds
YU20050423A RS52667B (sr)	2002-12-06	2003-12-03	Postupak za pripremanje optički čistih jedinjenja

Publications (1)

Publication Number	Publication Date
ME00563A true ME00563A (en)	2011-12-20

Family

ID=32509784

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MEP-848/08A ME00563A (en)	2002-12-06	2003-12-03	Process for preparing optically pure active compounds

Country Status (27)

Country	Link
US (1)	US7452998B2 (is)
EP (1)	EP1578742B1 (is)
JP (1)	JP4612542B2 (is)
KR (1)	KR101062806B1 (is)
CN (1)	CN100482658C (is)
AR (1)	AR042277A1 (is)
AU (1)	AU2003289948B2 (is)
BR (2)	BR0317005A (is)
CA (1)	CA2507807C (is)
CY (1)	CY1114058T1 (is)
DK (1)	DK1578742T3 (is)
EA (1)	EA011771B1 (is)
ES (1)	ES2397380T3 (is)
HR (1)	HRP20050604B1 (is)
IL (1)	IL168456A (is)
IS (1)	IS2885B (is)
ME (1)	ME00563A (is)
MX (1)	MXPA05005762A (is)
NO (1)	NO330978B1 (is)
NZ (1)	NZ540815A (is)
PL (1)	PL375818A1 (is)
PT (1)	PT1578742E (is)
RS (1)	RS52667B (is)
SI (1)	SI1578742T1 (is)
TW (1)	TWI313268B (is)
WO (1)	WO2004052882A1 (is)
ZA (1)	ZA200503543B (is)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE538794T1 (de)	1999-01-13	2012-01-15	Bayer Healthcare Llc	Gamma carboxyarylsubstituierte diphenylharnstoffverbindungen als p38 kinasehemmer
ATE553103T1 (de)	2002-12-06	2012-04-15	Nycomed Gmbh	Verfahren zur herstellung von (s)-pantoprazol
FR2848555B1 (fr) *	2002-12-16	2006-07-28	Negma Gild	Enantiomere(-)du tenatoprazole et son application en therapeutique
WO2004056804A2 (en) *	2002-12-19	2004-07-08	Teva Pharmaceutical Industries Ltd.	Solid states of pantoprazole sodium, processes for preparing them and processes for preparing known pantoprazole sodium hydrates
CA2528993A1 (en) *	2003-06-10	2004-12-23	Teva Pharmaceutical Industries Ltd.	Process for preparing 2-[(pyridinyl)methyl]sulfinyl-substituted benzimidazoles and novel chlorinated derivatives of pantoprazole
WO2005118569A1 (en) *	2004-06-02	2005-12-15	Altana Pharma Ag	Process for the preparation of pyridin-2-ylmethylsulphinyl-1h-benzimidazol compounds
FR2871800B1 (fr) *	2004-06-17	2006-08-25	Sidem Pharma Sa Sa	Sel de sodium monohydrate du s-tenatoprazole et application en therapeutique
KR20130038949A (ko) *	2004-06-24	2013-04-18	아스트라제네카 아베	에소메프라졸 나트륨염의 제조에서 사용하기 위한 결정 변형의 제조를 위한 신규한 방법
EP1801110A1 (en)	2005-12-22	2007-06-27	KRKA, tovarna zdravil, d.d., Novo mesto	Esomeprazole arginine salt
US7579476B2 (en) *	2006-02-24	2009-08-25	Praktikatalyst Pharma, Llc	Transition metal mediated oxidation of hetero atoms in organic molecules coordinated to transition metals
CA2660112A1 (en)	2006-08-08	2008-02-14	Jubilant Organosys Limited	Process for producing sulphoxide compounds
EP2065379A4 (en)	2006-10-13	2011-01-19	Eisai R&D Man Co Ltd	BENZIMIDAZOLE HAVING INHIBITORY ACTIVITY OF GASTRIC ACID SECRETION
WO2008057802A2 (en)	2006-10-27	2008-05-15	The Curators Of The University Of Missouri	Compositions comprising at least one acid labile proton pump inhibiting agents, optionally other pharmaceutically active agents and methods of using same
CA2717578A1 (en) *	2008-03-18	2009-09-24	Dr. Reddy's Laboratories Ltd.	Dexlansoprazole process and polymorphs
EP2143722A1 (en)	2008-07-09	2010-01-13	Lek Pharmaceuticals D.D.	Process for preparation of esomeprazole sodium of high chemical purity and new forms of esomeprazole sodium
EP2264024A1 (en)	2008-10-14	2010-12-22	LEK Pharmaceuticals d.d.	Process for the preparation of enantiomerically enriched proton pump inhibitors
US8071781B2 (en) *	2008-11-11	2011-12-06	Syn-Tech Chem. & Pharm. Co., Ltd.	Process for preparing rabeprazole sodium
JP5714031B2 (ja)	2010-02-12	2015-05-07	エステヴェキミカ，エス．エー．	エソメプラゾールナトリウムのナトリウム塩の調製方法
CN103113351B (zh) *	2013-03-08	2015-01-21	苏州特瑞药业有限公司	一种光学纯手性亚砜类化合物的制备方法
CN103936714A (zh) *	2014-04-15	2014-07-23	北京华禧联合科技发展有限公司	一种埃索美拉唑镁的制备方法
EP3239146A4 (en)	2014-12-26	2018-05-30	The University of Tokyo	Method for producing proton pump inhibitor compound having optical activity
CN105440018A (zh) *	2015-11-27	2016-03-30	福州闽海药业有限公司	一种锆催化的右旋兰索拉唑的不对称氧化合成方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE7804231L (sv)	1978-04-14	1979-10-15	Haessle Ab	Magsyrasekretionsmedel
IL75400A (en)	1984-06-16	1988-10-31	Byk Gulden Lomberg Chem Fab	Dialkoxypyridine methyl(sulfinyl or sulfonyl)benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing the same
JPS6150978A (ja)	1984-08-16	1986-03-13	Takeda Chem Ind Ltd	ピリジン誘導体およびその製造法
FI90544C (fi)	1986-11-13	1994-02-25	Eisai Co Ltd	Menetelmä lääkeaineina käyttökelpoisten 2-pyridin-2-yyli-metyylitio- ja sulfinyyli-1H-bensimidatsolijohdannaisten valmistamiseksi
SE465514B (sv)	1990-02-19	1991-09-23	Curt Pettersson	Foerfarande och anvaendning av ett separationsmedium vid separation av enantiomerer
DE4035455A1 (de)	1990-11-08	1992-05-14	Byk Gulden Lomberg Chem Fab	Enantiomerentrennung
CA2161256C (en)	1993-04-27	2004-06-29	Nancy M. Gray	Methods and compositions for treating gastric disorders using optically pure (-) pantoprazole
CA2161130A1 (en)	1993-04-27	1994-11-10	Nancy M. Gray	Methods and compositions for treating gastric disorders using optically pure (+) pantoprazole
SE9301830D0 (sv)	1993-05-28	1993-05-28	Ab Astra	New compounds
SE504459C2 (sv)	1994-07-15	1997-02-17	Astra Ab	Förfarande för framställning av substituerade sulfoxider
GB9423970D0 (en)	1994-11-28	1995-01-11	Astra Ab	Oxidation
GB9423968D0 (en)	1994-11-28	1995-01-11	Astra Ab	Resolution
HRP960232A2 (en)	1995-07-03	1998-02-28	Astra Ab	A process for the optical purification of compounds
ATE553103T1 (de)	2002-12-06	2012-04-15	Nycomed Gmbh	Verfahren zur herstellung von (s)-pantoprazol

2003
- 2003-12-03 US US10/536,766 patent/US7452998B2/en not_active Expired - Fee Related
- 2003-12-03 JP JP2005502310A patent/JP4612542B2/ja not_active Expired - Fee Related
- 2003-12-03 PL PL03375818A patent/PL375818A1/xx not_active Application Discontinuation
- 2003-12-03 HR HRP20050604AA patent/HRP20050604B1/hr not_active IP Right Cessation
- 2003-12-03 KR KR1020057009778A patent/KR101062806B1/ko not_active Expired - Fee Related
- 2003-12-03 DK DK03782288.9T patent/DK1578742T3/da active
- 2003-12-03 CA CA2507807A patent/CA2507807C/en not_active Expired - Fee Related
- 2003-12-03 SI SI200332234T patent/SI1578742T1/sl unknown
- 2003-12-03 ME MEP-848/08A patent/ME00563A/xx unknown
- 2003-12-03 PT PT37822889T patent/PT1578742E/pt unknown
- 2003-12-03 MX MXPA05005762A patent/MXPA05005762A/es active IP Right Grant
- 2003-12-03 RS YU20050423A patent/RS52667B/sr unknown
- 2003-12-03 CN CNB2003801044100A patent/CN100482658C/zh not_active Expired - Fee Related
- 2003-12-03 WO PCT/EP2003/013605 patent/WO2004052882A1/en not_active Ceased
- 2003-12-03 AU AU2003289948A patent/AU2003289948B2/en not_active Ceased
- 2003-12-03 ES ES03782288T patent/ES2397380T3/es not_active Expired - Lifetime
- 2003-12-03 NZ NZ540815A patent/NZ540815A/en not_active IP Right Cessation
- 2003-12-03 EA EA200500898A patent/EA011771B1/ru not_active IP Right Cessation
- 2003-12-03 BR BR0317005-5A patent/BR0317005A/pt unknown
- 2003-12-03 AR ARP030104447A patent/AR042277A1/es unknown
- 2003-12-03 BR BRPI0310118A patent/BRPI0310118B1/pt not_active IP Right Cessation
- 2003-12-03 EP EP03782288A patent/EP1578742B1/en not_active Expired - Lifetime
- 2003-12-05 TW TW092134409A patent/TWI313268B/zh not_active IP Right Cessation
2005
- 2005-05-04 ZA ZA200503543A patent/ZA200503543B/en unknown
- 2005-05-05 IL IL168456A patent/IL168456A/en not_active IP Right Cessation
- 2005-06-23 IS IS7909A patent/IS2885B/is unknown
- 2005-06-24 NO NO20053099A patent/NO330978B1/no not_active IP Right Cessation
2013
- 2013-01-07 CY CY20131100012T patent/CY1114058T1/el unknown

Also Published As

Publication number	Publication date
RS20050423A (sr)	2007-04-10
CN100482658C (zh)	2009-04-29
HRP20050604B1 (hr)	2013-09-30
SI1578742T1 (sl)	2013-02-28
RS52667B (sr)	2013-06-28
CA2507807C (en)	2013-10-22
TW200508219A (en)	2005-03-01
DK1578742T3 (da)	2013-01-21
IS7909A (is)	2005-06-23
JP2006516261A (ja)	2006-06-29
AU2003289948A1 (en)	2004-06-30
KR101062806B1 (ko)	2011-09-07
EA011771B1 (ru)	2009-06-30
IL168456A (en)	2012-02-29
NO330978B1 (no)	2011-08-29
BRPI0310118B1 (pt)	2015-10-20
AR042277A1 (es)	2005-06-15
NO20053099L (no)	2005-06-24
HK1078864A1 (en)	2006-03-24
EA200500898A1 (ru)	2005-12-29
PT1578742E (pt)	2013-01-24
TWI313268B (en)	2009-08-11
BR0317005A (pt)	2005-10-25
CY1114058T1 (el)	2016-07-27
ES2397380T3 (es)	2013-03-06
CN1717403A (zh)	2006-01-04
ZA200503543B (en)	2006-08-30
NO20053099D0 (no)	2005-06-24
IS2885B (is)	2014-07-15
US7452998B2 (en)	2008-11-18
EP1578742A1 (en)	2005-09-28
KR20050085224A (ko)	2005-08-29
JP4612542B2 (ja)	2011-01-12
EP1578742B1 (en)	2012-10-17
WO2004052882A1 (en)	2004-06-24
AU2003289948B2 (en)	2009-12-24
PL375818A1 (en)	2005-12-12
NZ540815A (en)	2008-03-28
MXPA05005762A (es)	2005-08-16
US20050288334A1 (en)	2005-12-29
HRP20050604A2 (en)	2006-09-30
CA2507807A1 (en)	2004-06-24

Publication	Publication Date	Title
ME00563A (en)	2011-12-20	Process for preparing optically pure active compounds
ECSP034865A (es)	2004-01-28	Resolución óptica de (1-benzilo-4-metilopiperidina-3-il)-metilamina y su uso para la preparación de derivados de pirrolo 2,3-pirimidina como inhibidores de proteina quinasas
FR2889526B1 (fr)	2012-02-17	7-aza-indazoles substitues, compositions les contenant, procede de fabrication et utilisation
AP1635A (en)	2006-07-14	Azabicyclic-substituted fused-heteroaryl compounds for the treatment of disease.
DE60329237D1 (de)	2009-10-22	Kristalline form von linezolid
CO6190512A2 (es)	2010-08-19	Compuestos antagonistas del receptor de glucagon composiciones que contienen dichos compuestos y procedimientos de uso
MA30427B1 (fr)	2009-05-04	Derives bicycliques utilises comme inhibiteurs de cetp
ATE440999T1 (de)	2009-09-15	Verbesserungen betreffend optische aufheller
HRP20050870A2 (en)	2006-10-31	Novel diphenyl azetidinone with improved physiological characteristics, corresponding production method, medicaments containing said compound and use of the latter
EA200200819A1 (ru)	2003-02-27	Кристаллическая форма ii линезолида
DE60112956D1 (de)	2005-09-29	Kristalline formen von fluvastatin sodium
BR0316702A (pt)	2005-10-18	xprocesso para preparação de (s)-pantoprazol
DE60319707D1 (de)	2008-04-24	Pharmazeutische zusammensetzung enthaltend ein benzimidazol-derivat gemischt mit mikrokristalliner cellulose
ATE345340T1 (de)	2006-12-15	N-substituierte-1h-indol-5-propansäure verbindungen als ppar-agonisten zur behandlung von diabetis
ATE457982T1 (de)	2010-03-15	Thiazol-(bi)cycloalkyl-carboxanilide
EA200701738A1 (ru)	2007-12-28	Способ получения транс-1-((1r,3s)-6-хлор-3-фенилиндан-1-ил)-3,3-диметилпиперазина
ATE472552T1 (de)	2010-07-15	Fluorisierungsverfahren zur synthese von 2-ä18fü fluoro-2-deoxy-d-glukose
DE502005011199D1 (de)	2011-05-12	Herstellung eines von willenbrand faktor-präparates mit hoher spezifischer aktivität
DE69300453D1 (de)	1995-10-12	Isoindolinon-derivat, seine herstellung und dieses enthaltende pharmazeutische zusammen setzungen.
DE502004009136D1 (de)	2009-04-23	NEUE HETEROARYLSUBSTITUIERTE ACETONDERIVATE ALS HEMMSTOFFE DER PHOSPHOLIPASE A sb 2 /sb
DE602004006021D1 (de)	2007-05-31	Verfahren zur racematspaltung von nefopam
ATE282726T1 (de)	2004-12-15	Herstellung von verbindungen auf basis von cu-in- se phasengleichgewichten
DE602004014739D1 (de)	2008-08-14	Chemoenzymatisches verfahren zur stereoselektiven herstellung von optisch-angereicherten phenylglycidate
ATE299532T1 (de)	2005-07-15	Chemo-enzymatische synthese von optisch- angereicherten rosenoxiden
WO2003074536A1 (en)	2003-09-12	Novel organosilicon compound, optically active isomers thereof, process for producing the organosilicon compound, and use thereof