MEP49908A - Azaindoles - Google Patents

Azaindoles

Info

Publication number
MEP49908A
MEP49908A MEP-499/08A MEP49908A MEP49908A ME P49908 A MEP49908 A ME P49908A ME P49908 A MEP49908 A ME P49908A ME P49908 A MEP49908 A ME P49908A
Authority
ME
Montenegro
Prior art keywords
ny3y4
compounds
halo
heteroaryl
cyano
Prior art date
Application number
MEP-499/08A
Other languages
English (en)
Croatian (hr)
Unknown language (me)
Inventor
Paul Joseph Cox
Tahir Nadeem Majid
Justine Yeun Quai Lai
Andrew David Morley
Shelley Amendola
Stephanie Deprets
Chris Edlin
Original Assignee
Aventis Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Ltd filed Critical Aventis Pharma Ltd
Priority claimed from PCT/GB2000/004993 external-priority patent/WO2001047922A2/en
Publication of MEP49908A publication Critical patent/MEP49908A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
MEP-499/08A 1999-12-24 2000-12-27 Azaindoles MEP49908A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9930698.7A GB9930698D0 (en) 1999-12-24 1999-12-24 Chemical compounds
US21581800P 2000-07-05 2000-07-05
PCT/GB2000/004993 WO2001047922A2 (en) 1999-12-24 2000-12-27 Azaindoles
YUP-462/02A RS51303B (sr) 1999-12-24 2000-12-27 Azaindoli

Publications (1)

Publication Number Publication Date
MEP49908A true MEP49908A (en) 2011-02-10

Family

ID=10867079

Family Applications (1)

Application Number Title Priority Date Filing Date
MEP-499/08A MEP49908A (en) 1999-12-24 2000-12-27 Azaindoles

Country Status (12)

Country Link
JP (1) JP4871474B2 (de)
AT (2) ATE552258T1 (de)
DE (1) DE60044946D1 (de)
DK (2) DK1263759T3 (de)
ES (2) ES2382759T3 (de)
GB (1) GB9930698D0 (de)
ME (1) MEP49908A (de)
PL (1) PL218884B1 (de)
PT (2) PT1990343E (de)
RS (2) RS20100123A (de)
UA (1) UA76410C2 (de)
ZA (1) ZA200204126B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0422057D0 (en) * 2004-10-05 2004-11-03 Astrazeneca Ab Novel compounds
WO2007076348A2 (en) * 2005-12-23 2007-07-05 Smithkline Beecham Corporation Azaindole inhibitors of aurora kinases
CL2007002617A1 (es) * 2006-09-11 2008-05-16 Sanofi Aventis Compuestos derivados de pirrolo[2,3-b]pirazin-6-ilo; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar inflamacion de las articulaciones, artritis reumatoide, tumores, linfoma de las celulas del manto.
JP5274805B2 (ja) * 2006-09-20 2013-08-28 三菱化学株式会社 フッ素化芳香族化合物の製造方法
ES2464458T3 (es) * 2008-12-05 2014-06-02 F. Hoffmann-La Roche Ag Pirrolopirazinil-ureas como inhibidores de quinasas
JP2013503132A (ja) * 2009-08-26 2013-01-31 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング メチルピロロピリジンカルボキサミド
MX2015012899A (es) * 2013-03-14 2016-06-02 Abbvie Inc Pirrolo [2,3-b] piridina como inhibidores de quinasa cdk9.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP9903330A2 (hu) * 1996-11-19 2000-03-28 Amgen Inc. Gyulladásgátló hatású, aril- és heteroaril csoporttal szubsztituált kondenzált pirrolszármazékok, valamint ezeket tartalmazó gyógyászati készítmények
WO1998047899A1 (en) * 1997-04-24 1998-10-29 Ortho-Mcneil Corporation, Inc. Substituted pyrrolopyridines useful in the treatment of inflammatory diseases
HRP20000209A2 (en) * 1997-10-20 2001-04-30 Hoffmann La Roche Bicyclic kinase inhibitors

Also Published As

Publication number Publication date
UA76410C2 (en) 2006-08-15
JP4871474B2 (ja) 2012-02-08
ES2382759T3 (es) 2012-06-13
ATE480537T1 (de) 2010-09-15
ES2348861T3 (es) 2010-12-16
YU46202A (sh) 2005-06-10
RS51303B (sr) 2010-12-31
PT1263759E (pt) 2010-11-02
RS20100123A (sr) 2010-12-31
DK1263759T3 (da) 2011-01-10
DE60044946D1 (de) 2010-10-21
JP2003519144A (ja) 2003-06-17
GB9930698D0 (en) 2000-02-16
ATE552258T1 (de) 2012-04-15
PT1990343E (pt) 2012-05-22
DK1990343T3 (da) 2012-07-23
ZA200204126B (en) 2003-08-25
PL218884B1 (pl) 2015-02-27

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