MX2017014284A - Proteinas de fusion. - Google Patents

Proteinas de fusion.

Info

Publication number
MX2017014284A
MX2017014284A MX2017014284A MX2017014284A MX2017014284A MX 2017014284 A MX2017014284 A MX 2017014284A MX 2017014284 A MX2017014284 A MX 2017014284A MX 2017014284 A MX2017014284 A MX 2017014284A MX 2017014284 A MX2017014284 A MX 2017014284A
Authority
MX
Mexico
Prior art keywords
fusion proteins
present
diabetes
useful
treatment
Prior art date
Application number
MX2017014284A
Other languages
English (en)
Other versions
MX388594B (es
Inventor
Duane Dickinson Craig
Bruce Baldwin David
Michael Beals John
Wesley Day Jonathan
Ihor Korytko Andrew
Alan Lazar Gregory
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=55953435&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2017014284(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of MX2017014284A publication Critical patent/MX2017014284A/es
Publication of MX388594B publication Critical patent/MX388594B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)

Abstract

La presente invención se refiere a proteínas de fusión que comprenden un agonista del receptor de insulina fusionado a una región Fc de lgG humana mediante el uso de un enlazador de péptido y el uso de tales proteínas de fusión en el tratamiento de diabetes. La proteína de fusión de la presente invención tiene un perfil de acción de tiempo prolongado y es útil para proporcionar un control de glucosa basal durante un período de tiempo prolongado.
MX2017014284A 2015-05-07 2016-04-28 Proteinas de fusion. MX388594B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562158079P 2015-05-07 2015-05-07
PCT/US2016/029807 WO2016178905A1 (en) 2015-05-07 2016-04-28 Fusion proteins

Publications (2)

Publication Number Publication Date
MX2017014284A true MX2017014284A (es) 2018-03-23
MX388594B MX388594B (es) 2025-03-20

Family

ID=55953435

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017014284A MX388594B (es) 2015-05-07 2016-04-28 Proteinas de fusion.

Country Status (40)

Country Link
US (5) US9855318B2 (es)
EP (1) EP3292141B1 (es)
JP (1) JP6591562B2 (es)
KR (1) KR102059736B1 (es)
CN (1) CN107531806B (es)
AR (1) AR105616A1 (es)
AU (1) AU2016257659B2 (es)
CA (1) CA2981102A1 (es)
CL (1) CL2017002761A1 (es)
CO (1) CO2017011301A2 (es)
CR (1) CR20170469A (es)
CY (1) CY1122929T1 (es)
DK (1) DK3292141T3 (es)
DO (1) DOP2017000258A (es)
EA (1) EA039770B1 (es)
EC (1) ECSP17073650A (es)
ES (1) ES2799099T3 (es)
HR (1) HRP20200503T1 (es)
IL (1) IL254965B (es)
JO (1) JO3658B1 (es)
LT (1) LT3292141T (es)
MA (1) MA42037B1 (es)
MD (1) MD3292141T2 (es)
ME (1) ME03709B (es)
MX (1) MX388594B (es)
MY (1) MY183025A (es)
NZ (1) NZ736470A (es)
PE (1) PE20180507A1 (es)
PH (1) PH12017502025A1 (es)
PL (1) PL3292141T3 (es)
PT (1) PT3292141T (es)
RS (1) RS60044B1 (es)
SG (1) SG11201708194WA (es)
SI (1) SI3292141T1 (es)
SV (1) SV2017005548A (es)
TN (1) TN2018000059A1 (es)
TW (1) TWI656132B (es)
UA (1) UA122146C2 (es)
WO (1) WO2016178905A1 (es)
ZA (1) ZA201706334B (es)

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Publication number Publication date
CN107531806B (zh) 2022-06-07
SI3292141T1 (sl) 2020-04-30
EA201792199A1 (ru) 2018-03-30
CO2017011301A2 (es) 2018-03-20
KR102059736B1 (ko) 2019-12-26
PH12017502025B1 (en) 2018-04-02
JP6591562B2 (ja) 2019-10-16
TW201712029A (zh) 2017-04-01
ES2799099T3 (es) 2020-12-14
PT3292141T (pt) 2020-04-22
US20160324932A1 (en) 2016-11-10
US9855318B2 (en) 2018-01-02
US20180177851A1 (en) 2018-06-28
KR20170134614A (ko) 2017-12-06
NZ736470A (en) 2019-04-26
SV2017005548A (es) 2018-04-24
TWI656132B (zh) 2019-04-11
MX388594B (es) 2025-03-20
CA2981102A1 (en) 2016-11-10
BR112017020502A2 (pt) 2018-07-03
MA42037B1 (fr) 2020-03-31
JP2018515088A (ja) 2018-06-14
TN2018000059A1 (en) 2019-07-08
US10709766B2 (en) 2020-07-14
EP3292141A1 (en) 2018-03-14
UA122146C2 (uk) 2020-09-25
PL3292141T3 (pl) 2020-06-29
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