MY8400040A - Preparation of 2-aryl-propionic acids by direct coupling utilizing a mixed dmagnesium malide complex - Google Patents

Preparation of 2-aryl-propionic acids by direct coupling utilizing a mixed dmagnesium malide complex

Info

Publication number: MY8400040A
Authority: MY; Malaysia
Prior art keywords: aryl; complex; dmagnesium; malide; mixed
Prior art date: 1977-02-16

Application number

MY40/84A

Other languages

English (en)

Original Assignee

Syntex Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-02-16

Filing date

1984-12-30

Publication date

1984-12-31

1977-12-19 Priority claimed from US05/863,290 external-priority patent/US4144397A/en

1984-12-30 Application filed by Syntex Corp filed Critical Syntex Corp

1984-12-31 Publication of MY8400040A publication Critical patent/MY8400040A/xx

Links

230000008878 coupling Effects 0.000 title 1
238000010168 coupling process Methods 0.000 title 1
238000005859 coupling reaction Methods 0.000 title 1
RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
125000003118 aryl group Chemical group 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
UUFQTNFCRMXOAE-UHFFFAOYSA-N 1-methylmethylene Chemical compound C[CH] UUFQTNFCRMXOAE-UHFFFAOYSA-N 0.000 abstract 1
-1 6-methoxy-2-naphthyl Chemical group 0.000 abstract 1
CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 abstract 1
WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
150000007513 acids Chemical class 0.000 abstract 1
239000000010 aprotic solvent Substances 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
229910052794 bromium Inorganic materials 0.000 abstract 1
229910052801 chlorine Inorganic materials 0.000 abstract 1
239000000460 chlorine Substances 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1
238000003786 synthesis reaction Methods 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
- C07C65/24—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
- C07C53/15—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen containing halogen
- C07C53/19—Acids containing three or more carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
- C07C63/14—Monocyclic dicarboxylic acids
- C07C63/15—Monocyclic dicarboxylic acids all carboxyl groups bound to carbon atoms of the six-membered aromatic ring
- C07C63/24—1,3 - Benzenedicarboxylic acid

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

MY40/84A 1977-02-16 1984-12-30 Preparation of 2-aryl-propionic acids by direct coupling utilizing a mixed dmagnesium malide complex MY8400040A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US76907077A	1977-02-16	1977-02-16
US05/863,290 US4144397A (en)	1977-02-16	1977-12-19	Preparation of 2-aryl-propionic acids by direct coupling utilizing a mixed magnesium halide complex

Publications (1)

Publication Number	Publication Date
MY8400040A true MY8400040A (en)	1984-12-31

Family

ID=27118118

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
MY40/84A MY8400040A (en)	1977-02-16	1984-12-30	Preparation of 2-aryl-propionic acids by direct coupling utilizing a mixed dmagnesium malide complex
MY39/84A MY8400039A (en)	1977-02-16	1984-12-30	2-aryl-propionic acid precursors

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
MY39/84A MY8400039A (en)	1977-02-16	1984-12-30	2-aryl-propionic acid precursors

Country Status (18)

Country	Link
CH (3)	CH640499A5 (de)
DD (3)	DD145107A5 (de)
DK (1)	DK156898C (de)
ES (1)	ES467037A1 (de)
FI (1)	FI64571C (de)
HK (2)	HK25483A (de)
HU (2)	HU179309B (de)
IE (1)	IE46614B1 (de)
IL (1)	IL54019A (de)
IT (1)	IT1107880B (de)
MY (2)	MY8400040A (de)
NO (1)	NO145435C (de)
NZ (1)	NZ186472A (de)
PL (1)	PL108144B1 (de)
PT (1)	PT67654B (de)
SE (3)	SE430155B (de)
SU (2)	SU1003749A3 (de)
YU (3)	YU41427B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8915531D0 (en) *	1989-07-06	1989-08-23	Ass Octel	Alkaline earth,transition and lanthanide metal inorganic salt complexes

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1459084A (en) *	1973-05-24	1976-12-22	Boots Co Ltd	Preparation of arylalkanoic acid

1978
- 1978-02-09 FI FI780417A patent/FI64571C/fi not_active IP Right Cessation
- 1978-02-09 HU HU78SI1618A patent/HU179309B/hu unknown
- 1978-02-09 HU HU802271A patent/HU183210B/hu unknown
- 1978-02-10 IL IL54019A patent/IL54019A/xx unknown
- 1978-02-10 IT IT67279/78A patent/IT1107880B/it active
- 1978-02-13 SE SE7801648A patent/SE430155B/sv not_active IP Right Cessation
- 1978-02-13 DK DK064578A patent/DK156898C/da not_active IP Right Cessation
- 1978-02-13 YU YU329/78A patent/YU41427B/xx unknown
- 1978-02-14 NZ NZ186472A patent/NZ186472A/xx unknown
- 1978-02-14 PT PT67654A patent/PT67654B/pt unknown
- 1978-02-14 IE IE320/78A patent/IE46614B1/en not_active IP Right Cessation
- 1978-02-15 SU SU782580499A patent/SU1003749A3/ru active
- 1978-02-15 DD DD78214577A patent/DD145107A5/de not_active IP Right Cessation
- 1978-02-15 DD DD78214578A patent/DD148212A5/de not_active IP Right Cessation
- 1978-02-15 DD DD78203717A patent/DD137099A5/de not_active IP Right Cessation
- 1978-02-15 NO NO780524A patent/NO145435C/no unknown
- 1978-02-15 CH CH167578A patent/CH640499A5/de not_active IP Right Cessation
- 1978-02-16 ES ES467037A patent/ES467037A1/es not_active Expired
- 1978-02-16 PL PL1978204667A patent/PL108144B1/pl unknown
- 1978-10-11 SU SU782672198A patent/SU963462A3/ru active
1982
- 1982-03-09 SE SE8201459A patent/SE453094B/sv not_active IP Right Cessation
- 1982-03-09 SE SE8201458A patent/SE453093B/sv not_active IP Right Cessation
- 1982-09-07 CH CH531782A patent/CH640498A5/de not_active IP Right Cessation
- 1982-09-07 CH CH531882A patent/CH640500A5/de not_active IP Right Cessation
1983
- 1983-03-10 YU YU587/83A patent/YU43302B/xx unknown
- 1983-03-10 YU YU588/83A patent/YU42843B/xx unknown
- 1983-08-04 HK HK254/83A patent/HK25483A/xx not_active IP Right Cessation
- 1983-08-04 HK HK253/83A patent/HK25383A/xx not_active IP Right Cessation
1984
- 1984-12-30 MY MY40/84A patent/MY8400040A/xx unknown
- 1984-12-30 MY MY39/84A patent/MY8400039A/xx unknown

Also Published As

Publication number	Publication date
YU41427B (en)	1987-06-30
NO145435C (no)	1982-03-24
SE453093B (sv)	1988-01-11
SE8201459L (sv)	1982-03-09
SE430155B (sv)	1983-10-24
YU43302B (en)	1989-06-30
NZ186472A (en)	1979-08-31
HK25383A (en)	1983-08-12
DD148212A5 (de)	1981-05-13
FI64571C (fi)	1983-12-12
IT7867279A0 (it)	1978-02-10
PL108144B1 (pl)	1980-03-31
SE453094B (sv)	1988-01-11
CH640498A5 (en)	1984-01-13
YU58783A (en)	1983-12-31
IE46614B1 (en)	1983-08-10
SE7801648L (sv)	1978-08-17
YU58883A (en)	1983-12-31
DK156898B (da)	1989-10-16
FI780417A7 (fi)	1978-08-17
YU42843B (en)	1988-12-31
NO780524L (no)	1978-08-17
PL204667A1 (pl)	1978-12-04
IE780320L (en)	1978-08-16
MY8400039A (en)	1984-12-31
HU183210B (en)	1984-04-28
SE8201458L (sv)	1982-03-09
DD137099A5 (de)	1979-08-15
YU32978A (en)	1983-06-30
SU1003749A3 (ru)	1983-03-07
HU179309B (en)	1982-09-28
DK64578A (da)	1978-08-17
ES467037A1 (es)	1978-11-01
IL54019A0 (en)	1978-04-30
CH640499A5 (en)	1984-01-13
DK156898C (da)	1990-03-12
IL54019A (en)	1981-06-29
PT67654A (en)	1978-03-01
SU963462A3 (ru)	1982-09-30
PT67654B (en)	1979-07-19
NO145435B (no)	1981-12-14
CH640500A5 (en)	1984-01-13
DD145107A5 (de)	1980-11-19
IT1107880B (it)	1985-12-02
FI64571B (fi)	1983-08-31
HK25483A (en)	1983-08-12

Publication	Publication Date	Title
MY8400040A (en)	1984-12-31	Preparation of 2-aryl-propionic acids by direct coupling utilizing a mixed dmagnesium malide complex
JPS56125361A (en)	1981-10-01	Azetidinone compound
ZA818995B (en)	1982-12-29	Process for the preparation of monochloromethyl ketones
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ES445263A1 (es)	1977-06-01	Un procedimiento para preparar un nuevo derivado de dimer- captoetileter.
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JPS55153777A (en)	1980-11-29	Improved method of preparation of 3-methyl-3-(substituted phenyl)-glycidic ester
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JPS55160755A (en)	1980-12-13	Preparation of alpha-isoproply-halo substituted phenylacetonitrile
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JPS549250A (en)	1979-01-24	Synthesis of n-mono-substituted aminobenzophenone derivatives
ES477098A2 (es)	1979-10-16	Mejoras en el objeto de la patente principal n.414366, por: procedimiento para la preparacion de mono y diesteres del acido 2,5-dihidroxibencenosulfonico.
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JPS5587799A (en)	1980-07-02	1-beta-d-arabinofuranosyl-5-vinyluracil and its preparation