|
US4855231A
(en)
*
|
1984-10-30 |
1989-08-08 |
Phillips Petroleum Company |
Regulatory region for heterologous gene expression in yeast
|
|
US4885242A
(en)
*
|
1984-10-30 |
1989-12-05 |
Phillips Petroleum Company |
Genes from pichia histidine pathway and uses thereof
|
|
US4818700A
(en)
*
|
1985-10-25 |
1989-04-04 |
Phillips Petroleum Company |
Pichia pastoris argininosuccinate lyase gene and uses thereof
|
|
US4882279A
(en)
*
|
1985-10-25 |
1989-11-21 |
Phillips Petroleum Company |
Site selective genomic modification of yeast of the genus pichia
|
|
US4895800A
(en)
*
|
1985-11-26 |
1990-01-23 |
Phillips Petroleum Company |
Yeast production of hepatitis B surface antigen
|
|
ZA872534B
(en)
*
|
1986-05-08 |
1987-11-25 |
Phillips Petroleum Co |
Yeast production of streptokinase
|
|
US5258287A
(en)
*
|
1988-03-22 |
1993-11-02 |
Genentech, Inc. |
DNA encoding and methods of production of insulin-like growth factor binding protein BP53
|
|
NZ228774A
(en)
*
|
1988-04-25 |
1991-05-28 |
Phillips Petroleum Co |
Hbv particles containing pres 2 proteins and recombinant processes for their production in yeast cells
|
|
IL89989A0
(en)
*
|
1988-04-25 |
1989-12-15 |
Phillips Petroleum Co |
Expression of human interleukin-2 in methylotrophic yeasts
|
|
US5204252A
(en)
*
|
1989-02-08 |
1993-04-20 |
Henkel Research Corporation |
Candida tropicalis transformation system
|
|
WO1990009434A1
(fr)
*
|
1989-02-13 |
1990-08-23 |
The Salk Institute Biotechnology/Industrial Associates, Inc. |
Production de peroxyde dismutase dans des cellules de levure de pichia pastoris
|
|
US5254466A
(en)
*
|
1989-11-06 |
1993-10-19 |
Henkel Research Corporation |
Site-specific modification of the candida tropicals genome
|
|
US5612198A
(en)
*
|
1990-09-04 |
1997-03-18 |
The Salk Institute |
Production of insulin-like growth factor-1 in methylotrophic yeast cells
|
|
WO1992013951A1
(fr)
*
|
1991-02-04 |
1992-08-20 |
The Salk Institute Biotechnology/Industrial Associates, Inc. |
Production de serumalbumine humaine dans des cellules de levure methylotrophique
|
|
WO1992017595A1
(fr)
*
|
1991-04-01 |
1992-10-15 |
The Salk Institute Biotechnology/Industrial Associates, Inc. |
Genes influançant l'activite proteolytique de pichia, et leurs utilisations
|
|
US6872550B1
(en)
*
|
1991-07-11 |
2005-03-29 |
Baxter Vaccine Ag |
Immunogenic formulation of OspC antigen vaccines for the prevention and treatment of lyme disease and recombinant methods for the preparation of such antigens
|
|
US5665600A
(en)
*
|
1991-09-18 |
1997-09-09 |
Research Corporation Technologies, Inc. |
Pichia pastoris linear plasmids and DNA fragments thereof
|
|
AU664469B2
(en)
|
1992-06-03 |
1995-11-16 |
Genentech Inc. |
Tissue plasminogen activator glycosylation variants with improved therapeutic properties
|
|
PL310523A1
(en)
*
|
1993-03-03 |
1995-12-27 |
Du Pont |
Method of producing glycolane oxidase in methylothrophic yeast
|
|
US5877016A
(en)
|
1994-03-18 |
1999-03-02 |
Genentech, Inc. |
Human trk receptors and neurotrophic factor inhibitors
|
|
US5708142A
(en)
|
1994-05-27 |
1998-01-13 |
Genentech, Inc. |
Tumor necrosis factor receptor-associated factors
|
|
US5866543A
(en)
*
|
1995-06-05 |
1999-02-02 |
Corvas International, Inc. |
Nematode-extracted anticoagulant protein
|
|
CA2202351A1
(fr)
*
|
1994-10-18 |
1996-04-25 |
George Phillip Vlasuk |
Proteines anticoagulantes et inhibiteurs de la serine-protease extraits de nematodes
|
|
DK0788546T3
(da)
*
|
1994-10-18 |
2007-04-10 |
Dendreon Corp |
Nematode-ekstraherede serinproteaseinhibitorer og antikoagulerende proteiner
|
|
US5872098A
(en)
*
|
1995-06-05 |
1999-02-16 |
Corvas International, Inc. |
Nematode-extracted anticoagulant protein
|
|
US5863894A
(en)
*
|
1995-06-05 |
1999-01-26 |
Corvas International, Inc. |
Nematode-extracted anticoagulant protein
|
|
US5945275A
(en)
*
|
1994-10-18 |
1999-08-31 |
Corvas International, Inc. |
Nematode-extracted anticoagulant protein
|
|
US5866542A
(en)
*
|
1994-10-18 |
1999-02-02 |
Corvas International, Inc. |
Nematode-extracted anticoagulant protein
|
|
ATE242809T1
(de)
|
1995-09-08 |
2003-06-15 |
Genentech Inc |
Vegf-verwandtes protein
|
|
US5955349A
(en)
*
|
1996-08-26 |
1999-09-21 |
Zymogenetics, Inc. |
Compositions and methods for producing heterologous polypeptides in Pichia methanolica
|
|
US5716808A
(en)
*
|
1995-11-09 |
1998-02-10 |
Zymogenetics, Inc. |
Genetic engineering of pichia methanolica
|
|
WO1997017451A2
(fr)
*
|
1995-11-09 |
1997-05-15 |
Zymogenetics, Inc. |
Production de gad65 dans une levure methylotrophe
|
|
IL125073A0
(en)
|
1996-01-08 |
1999-01-26 |
Genentech Inc |
Wsx receptor and ligands
|
|
US5736383A
(en)
*
|
1996-08-26 |
1998-04-07 |
Zymogenetics, Inc. |
Preparation of Pichia methanolica auxotrophic mutants
|
|
US5854039A
(en)
*
|
1996-07-17 |
1998-12-29 |
Zymogenetics, Inc. |
Transformation of pichia methanolica
|
|
US6159462A
(en)
*
|
1996-08-16 |
2000-12-12 |
Genentech, Inc. |
Uses of Wnt polypeptides
|
|
US5851984A
(en)
*
|
1996-08-16 |
1998-12-22 |
Genentech, Inc. |
Method of enhancing proliferation or differentiation of hematopoietic stem cells using Wnt polypeptides
|
|
MX9605082A
(es)
|
1996-10-24 |
1998-04-30 |
Univ Autonoma De Nuevo Leon |
Levaduras metilotroficas modificadas geneticamente para la produccion y secrecion de hormona de crecimiento humano.
|
|
ATE356212T1
(de)
|
1997-01-31 |
2007-03-15 |
Genentech Inc |
O-fukosyltransferase
|
|
US6100076A
(en)
|
1997-01-31 |
2000-08-08 |
Genentech, Inc. |
O-fucosyltransferase
|
|
WO1998045331A2
(fr)
|
1997-04-07 |
1998-10-15 |
Genentech, Inc. |
Anticorps anti-vegf
|
|
KR100856995B1
(ko)
|
1997-04-07 |
2008-09-04 |
제넨테크, 인크. |
인간화 항체 및 인간화 항체의 제조 방법
|
|
US6265186B1
(en)
|
1997-04-11 |
2001-07-24 |
Dsm N.V. |
Yeast cells comprising at least two copies of a desired gene integrated into the chromosomal genome at more than one non-ribosomal RNA encoding domain, particularly with Kluyveromyces
|
|
US6342220B1
(en)
|
1997-08-25 |
2002-01-29 |
Genentech, Inc. |
Agonist antibodies
|
|
DE69839942D1
(de)
|
1997-10-29 |
2008-10-09 |
Genentech Inc |
Verwendung des wnt-1 induzierten sekretierten polypeptids wisp-1
|
|
DE69840051D1
(de)
|
1997-10-29 |
2008-11-06 |
Genentech Inc |
Durch wnt-1 induzierbare gene
|
|
NZ525914A
(en)
|
1998-03-10 |
2004-03-26 |
Genentech Inc |
Novel polypeptides and nucleic acids encoding the same
|
|
IL138930A0
(en)
|
1998-05-15 |
2001-11-25 |
Genentech Inc |
Il-17 homologies polypeptides and therapeutic uses thereof
|
|
EP1865061A3
(fr)
|
1998-05-15 |
2007-12-19 |
Genentech, Inc. |
Polypeptides allogéniques IL-17 et utilisations thérapeutiques
|
|
EP3112468A1
(fr)
|
1998-05-15 |
2017-01-04 |
Genentech, Inc. |
Polypeptides allogéniques il-17 et utilisations thérapeutiques
|
|
US20020172678A1
(en)
|
2000-06-23 |
2002-11-21 |
Napoleone Ferrara |
EG-VEGF nucleic acids and polypeptides and methods of use
|
|
US6316245B1
(en)
*
|
1998-09-16 |
2001-11-13 |
Biongene Co., Ltd. |
Mutant cells of Pichia
|
|
EP1950300A3
(fr)
|
1998-11-18 |
2011-03-23 |
Genentech, Inc. |
Variantes d'anticorps avec une affinité de liaison plus élevée en comparaison aux anticorps parents
|
|
EP1820859B9
(fr)
|
1998-12-22 |
2009-10-28 |
Genentech, Inc. |
Procédés et compositions d'inhibition de la croissance de cellules néoplasiques
|
|
HUP0104865A3
(en)
|
1999-01-15 |
2004-07-28 |
Genentech Inc |
Polypeptide variants with altered effector function
|
|
US6720174B1
(en)
|
1999-01-28 |
2004-04-13 |
Novozymes A/S |
Phytases
|
|
AU5152700A
(en)
|
1999-06-15 |
2001-01-02 |
Genentech Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
ES2329437T3
(es)
|
1999-06-25 |
2009-11-26 |
Genentech, Inc. |
Anticuerpos anti-erbb2 humanizados y tratamiento con anticuerpos anti-erbb2.
|
|
AU7878900A
(en)
*
|
1999-10-15 |
2001-04-30 |
Heska Corporation |
Method for production and use of mite group 1 proteins
|
|
CA2494705A1
(fr)
|
1999-12-01 |
2001-06-07 |
Genentech, Inc. |
Polypeptides secretes et transmembranaires et acides nucleiques codant ces polypeptides
|
|
EP2290081A3
(fr)
|
1999-12-23 |
2012-08-01 |
Genentech, Inc. |
Polypeptides allogéniques IL-17 et utilisations thérapeutiques
|
|
WO2001077351A1
(fr)
*
|
2000-04-07 |
2001-10-18 |
MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. |
Vecteurs et procedes d'expression de proteine double dans pichia pastoris et escherichia coli
|
|
LT2857516T
(lt)
|
2000-04-11 |
2017-09-11 |
Genentech, Inc. |
Multivalentiniai antikūnai ir jų panaudojimas
|
|
EP2075253A1
(fr)
|
2000-06-23 |
2009-07-01 |
Genentech, Inc. |
Méthodes et composés pour la diagnose et le traitement de troubles associés à l'angiogenèse
|
|
DK2042597T3
(da)
|
2000-06-23 |
2014-08-11 |
Genentech Inc |
Sammensætninger og fremgangsmåder til diagnose og behandling af sygdomme, der involverer angiogenese
|
|
US8697394B2
(en)
*
|
2000-06-28 |
2014-04-15 |
Glycofi, Inc. |
Production of modified glycoproteins having multiple antennary structures
|
|
US7598055B2
(en)
|
2000-06-28 |
2009-10-06 |
Glycofi, Inc. |
N-acetylglucosaminyltransferase III expression in lower eukaryotes
|
|
US7449308B2
(en)
|
2000-06-28 |
2008-11-11 |
Glycofi, Inc. |
Combinatorial DNA library for producing modified N-glycans in lower eukaryotes
|
|
KR100787073B1
(ko)
*
|
2000-06-28 |
2007-12-21 |
글리코파이, 인크. |
변형된 당단백질의 제조방법
|
|
US7625756B2
(en)
|
2000-06-28 |
2009-12-01 |
GycoFi, Inc. |
Expression of class 2 mannosidase and class III mannosidase in lower eukaryotic cells
|
|
US7863020B2
(en)
*
|
2000-06-28 |
2011-01-04 |
Glycofi, Inc. |
Production of sialylated N-glycans in lower eukaryotes
|
|
CA2411968C
(fr)
|
2000-06-30 |
2009-12-15 |
Flanders Interuniversity Institute For Biotechnology (Vib) |
Modification de glycosylation de proteine dans pichia pastoris
|
|
US7009045B2
(en)
*
|
2000-07-14 |
2006-03-07 |
Archer-Daniels-Midland Company |
Transformation systems for flavinogenic yeast
|
|
EP1303293B1
(fr)
|
2000-07-27 |
2008-12-03 |
Genentech, Inc. |
Administration sequentielle de cpt-11 et d'apo 2l polypeptide
|
|
DE60136281D1
(de)
|
2000-08-24 |
2008-12-04 |
Genentech Inc |
Methode zur inhibierung von il-22 induziertem pap1
|
|
EP1944317A3
(fr)
|
2000-09-01 |
2008-09-17 |
Genentech, Inc. |
Polypeptides sécrétés et transmembranaires, et acides nucléiques les codant
|
|
US6673580B2
(en)
|
2000-10-27 |
2004-01-06 |
Genentech, Inc. |
Identification and modification of immunodominant epitopes in polypeptides
|
|
EP1487480B1
(fr)
|
2001-05-01 |
2015-10-07 |
The Regents of The University of California |
Molecules hybrides pour le traitement des maladies immunitaires
|
|
US7265208B2
(en)
|
2001-05-01 |
2007-09-04 |
The Regents Of The University Of California |
Fusion molecules and treatment of IgE-mediated allergic diseases
|
|
US20070160576A1
(en)
|
2001-06-05 |
2007-07-12 |
Genentech, Inc. |
IL-17A/F heterologous polypeptides and therapeutic uses thereof
|
|
ES2372321T3
(es)
|
2001-06-20 |
2012-01-18 |
Genentech, Inc. |
Composiciones y métodos para el diagnóstico y tratamiento de un tumor de pulmón.
|
|
JP4361791B2
(ja)
|
2001-08-29 |
2009-11-11 |
ジェネンテック・インコーポレーテッド |
マイトジェン活性を有するBv8核酸及びポリペプチド
|
|
ATE486092T1
(de)
|
2001-09-18 |
2010-11-15 |
Genentech Inc |
Zusammensetzungen und verfahren für die diagnose von tumoren
|
|
US20030228319A1
(en)
|
2002-04-16 |
2003-12-11 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
|
AU2002367318B2
(en)
|
2002-01-02 |
2007-07-12 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
|
US20040258678A1
(en)
|
2002-02-22 |
2004-12-23 |
Genentech, Inc. |
Compositions and methods for the treatment of immune related diseases
|
|
EP2305710A3
(fr)
|
2002-06-03 |
2013-05-29 |
Genentech, Inc. |
Bibliothèques de phages et anticorps synthétiques
|
|
EP1553912A4
(fr)
|
2002-06-07 |
2007-08-08 |
Genentech Inc |
Compositions et methodes pour le diagnostic et pour le traitement d'une tumeur
|
|
IL165717A0
(en)
|
2002-06-26 |
2006-01-15 |
Flanders Interuniversity Inst |
A strain of methylotrophic yeast for producing proteins
|
|
PT1585966E
(pt)
|
2002-07-15 |
2012-02-20 |
Hoffmann La Roche |
Tratamento de cancro com o anticorpo anti-erbb2 rhumab 2c4
|
|
AU2003276874B2
(en)
|
2002-09-11 |
2009-09-03 |
Genentech, Inc. |
Novel compositions and methods for the treatment of immune related diseases
|
|
CA2496060C
(fr)
|
2002-09-11 |
2015-08-04 |
Genentech, Inc. |
Purification de proteines par chromatographie a echange d'ions
|
|
DE60335552D1
(de)
|
2002-09-11 |
2011-02-10 |
Genentech Inc |
Neue zusammensetzung und verfahren zur behandlung von immunerkrankungen
|
|
JP2006515165A
(ja)
|
2002-09-16 |
2006-05-25 |
ジェネンテック・インコーポレーテッド |
免疫関連疾患の治療のための新規組成物と方法
|
|
CA2499843A1
(fr)
|
2002-09-25 |
2004-04-08 |
Genentech, Inc. |
Nouvelles compositions et methodes de traitement du psoriasis
|
|
CA2503330A1
(fr)
|
2002-10-29 |
2004-05-13 |
Genentech, Inc. |
Compositions et methodes de traitement de maladies liees au systeme immunitaire
|
|
AU2003295401B2
(en)
|
2002-11-08 |
2010-04-29 |
Genentech, Inc. |
Compositions and methods for the treatment of natural killer cell related diseases
|
|
CA2504144A1
(fr)
|
2002-11-26 |
2004-06-10 |
Genentech, Inc. |
Compositions et procedes pour le diagnostic de maladies de nature immune au moyen d'un polypeptide pro7
|
|
CN103833854B
(zh)
|
2002-12-16 |
2017-12-12 |
健泰科生物技术公司 |
免疫球蛋白变体及其用途
|
|
US7118901B2
(en)
*
|
2002-12-18 |
2006-10-10 |
Roche Diagnostics Operations, Inc. |
Recombinant bovine pancreatic desoxyribonuclease I with high specific activity
|
|
ATE387494T1
(de)
*
|
2002-12-20 |
2008-03-15 |
Hoffmann La Roche |
Hitzelabile desoxyribonuklease i-varianten
|
|
CA2513113A1
(fr)
|
2003-01-23 |
2004-08-05 |
Genentech, Inc. |
Procedes de production d'anticoprs humanises et d'amelioration du rendement d'anticorps ou de fragments de liaison d'antigenes en culture cellulaire
|
|
US7332299B2
(en)
*
|
2003-02-20 |
2008-02-19 |
Glycofi, Inc. |
Endomannosidases in the modification of glycoproteins in eukaryotes
|
|
AU2004219592C1
(en)
|
2003-03-12 |
2011-02-24 |
Genentech, Inc. |
Use of Bv8 and/or EG-VEGF to promote hematopoiesis
|
|
EP1460425A1
(fr)
*
|
2003-03-17 |
2004-09-22 |
Boehringer Mannheim Gmbh |
Enzymes déglycosylés pour conjugués
|
|
EP1610820B2
(fr)
|
2003-04-04 |
2013-08-21 |
Genentech, Inc. |
Preparations d'anticorps et de proteines a forte concentration
|
|
RS20150135A1
(sr)
|
2003-05-30 |
2015-08-31 |
Genentech Inc. |
Tretman sa anti-vegf antitelima
|
|
ES2371072T3
(es)
|
2003-06-12 |
2011-12-27 |
Eli Lilly And Company |
Proteínas de fusión análogas de glp-1.
|
|
MXPA06000347A
(es)
|
2003-07-08 |
2006-03-28 |
Genentech Inc |
Polipeptidos heterologos il-17 a/f y usos terapeuticos de los mismos.
|
|
US20050106667A1
(en)
|
2003-08-01 |
2005-05-19 |
Genentech, Inc |
Binding polypeptides with restricted diversity sequences
|
|
WO2005019258A2
(fr)
|
2003-08-11 |
2005-03-03 |
Genentech, Inc. |
Compositions et methodes de traitement de maladies relatives au systeme immunitaire
|
|
EP1673457B1
(fr)
*
|
2003-08-25 |
2011-05-18 |
Funzyme Biotechnologies SA |
Nouvelles proteines fongiques et acides nucleiques codant pour celles-ci
|
|
AU2004291141B2
(en)
|
2003-11-17 |
2009-06-11 |
Genentech, Inc. |
Compositions and methods for the treatment of tumor of hematopoietic origin
|
|
CA2486195C
(fr)
*
|
2003-12-05 |
2012-03-06 |
Stephan Glaser |
Carboxypeptidase b exprimee par ecombinaison et sa purification
|
|
PL2311873T3
(pl)
|
2004-01-07 |
2019-01-31 |
Novartis Vaccines And Diagnostics, Inc. |
Przeciwciało monoklonalne specyficzne wobec M-CSF i jego zastosowania
|
|
WO2005078074A2
(fr)
|
2004-02-13 |
2005-08-25 |
Novozymes A/S |
Variants de protease
|
|
AU2005229457B2
(en)
|
2004-03-30 |
2010-11-25 |
Glaxo Group Limited |
Immunoglobulins
|
|
US7794713B2
(en)
|
2004-04-07 |
2010-09-14 |
Lpath, Inc. |
Compositions and methods for the treatment and prevention of hyperproliferative diseases
|
|
US20150017671A1
(en)
|
2004-04-16 |
2015-01-15 |
Yaping Shou |
Methods for detecting lp-pla2 activity and inhibition of lp-pla2 activity
|
|
TWI307630B
(en)
|
2004-07-01 |
2009-03-21 |
Glaxo Group Ltd |
Immunoglobulins
|
|
ES2339789T3
(es)
|
2004-07-20 |
2010-05-25 |
Genentech, Inc. |
Inhibidores de proteina 4 de tipo angiopoyetina, combinaciones y su utilizacion.
|
|
US20090136490A1
(en)
|
2004-11-10 |
2009-05-28 |
Diadexus, Inc. |
Ovr110 antibody compositions and methods for use
|
|
ATE462726T1
(de)
|
2005-01-07 |
2010-04-15 |
Diadexus Inc |
Ovr110-antikörperzusammensetzungen und verwendungsverfahren dafür
|
|
RU2290434C1
(ru)
*
|
2005-06-02 |
2006-12-27 |
Общество с ограниченной ответственностью "БиоГениус" |
Штамм дрожжей pichia pastoris 2-2 - продуцент тромбоцитарного фактора роста человека (pdgf-bb) и способ получения тромбоцитарного фактора роста человека
|
|
EP1871163A2
(fr)
|
2005-06-06 |
2008-01-02 |
Genentech, Inc. |
Nouvelles interruptions geniques, compositions et methodes associees
|
|
JP2009504183A
(ja)
|
2005-08-15 |
2009-02-05 |
ジェネンテック・インコーポレーテッド |
遺伝子破壊、それに関連する組成物および方法
|
|
ATE513921T1
(de)
|
2005-08-16 |
2011-07-15 |
Novo Nordisk As |
Verfahren zur herstellung reifer insulinpolypeptide
|
|
PL1926749T3
(pl)
*
|
2005-09-14 |
2011-12-30 |
Sanofi Aventis Deutschland |
Cięcie prekursorów insuliny przez wariant trypsyny
|
|
UA96139C2
(uk)
|
2005-11-08 |
2011-10-10 |
Дженентек, Інк. |
Антитіло до нейропіліну-1 (nrp1)
|
|
KR101442266B1
(ko)
|
2005-11-18 |
2014-11-04 |
그렌마크 파머수티칼스 에스. 아. |
항-알파2 인테그린 항체 및 이의 용도
|
|
AU2006335053A1
(en)
|
2005-11-21 |
2007-07-19 |
Genentech, Inc. |
Novel gene disruptions, compositions and methods relating thereto
|
|
GB0525662D0
(en)
|
2005-12-16 |
2006-01-25 |
Glaxo Group Ltd |
Immunoglobulins
|
|
CA2638821A1
(fr)
|
2006-02-17 |
2007-10-11 |
Genentech, Inc. |
Nouvelles disruption geniques, compositions et procedes associes
|
|
SG170728A1
(en)
|
2006-03-23 |
2011-05-30 |
Novartis Ag |
Anti-tumor cell antigen antibody therapeutics
|
|
EP2004689A4
(fr)
|
2006-04-05 |
2010-06-02 |
Abbott Biotech Ltd |
Purification d'anticorps
|
|
CA2647277A1
(fr)
|
2006-04-05 |
2007-11-08 |
Genentech, Inc. |
Methode d'utilisation du boc/cdo pour moduler l'emission des signaux du hedgehog
|
|
EP2010662A2
(fr)
|
2006-04-19 |
2009-01-07 |
Genentech, Inc. |
Nouvelles disruptions génétiques, compositions et procédés les concernant
|
|
AU2007244683A1
(en)
|
2006-04-27 |
2007-11-08 |
Pikamab, Inc. |
Methods and compositions for antibody therapy
|
|
JP2009537147A
(ja)
|
2006-05-15 |
2009-10-29 |
シー レーン バイオテクノロジーズ, エルエルシー |
インフルエンザウイルスに対する中和抗体
|
|
US7862812B2
(en)
|
2006-05-31 |
2011-01-04 |
Lpath, Inc. |
Methods for decreasing immune response and treating immune conditions
|
|
EP2044111B1
(fr)
|
2006-06-21 |
2014-08-13 |
MUSC Foundation For Research Development |
Ciblage du facteur h du système complémentaire destiné au traitement de maladies
|
|
RU2499001C2
(ru)
|
2006-06-30 |
2013-11-20 |
Ново Нордиск А/С |
Антитела к nkg2a и их применения
|
|
SI2059535T1
(sl)
|
2006-08-18 |
2014-03-31 |
Novartis Ag |
Za prlr specifiäśno protitelo in njegove uporabe
|
|
EP2069502B1
(fr)
|
2006-09-27 |
2014-02-26 |
Novo Nordisk A/S |
Procédé de fabrication de polypeptides d'insuline mature
|
|
US7829674B2
(en)
|
2006-10-27 |
2010-11-09 |
Lpath, Inc. |
Compositions and methods for binding sphingosine-1-phosphate
|
|
AU2007313822A1
(en)
|
2006-10-27 |
2008-05-08 |
Lpath, Inc. |
Compositions and methods for treating ocular diseases and conditions
|
|
JP5519287B2
(ja)
|
2006-11-02 |
2014-06-11 |
ダニエル・ジェイ・カポン |
可動部を備えたハイブリッド免疫グロブリン
|
|
CA2667376A1
(fr)
|
2006-11-14 |
2008-05-22 |
Genentech, Inc. |
Modulateurs de la regeneration neuronale
|
|
JP5537946B2
(ja)
|
2006-11-22 |
2014-07-02 |
ブリストル−マイヤーズ スクイブ カンパニー |
Igf−irを含むチロシンキナーゼ受容体に対する改変タンパク質に基づく標的治療薬
|
|
EP2104513B1
(fr)
|
2006-11-27 |
2015-05-20 |
diaDexus, Inc. |
Compositions d'anticorps ovr110 et leurs procédés d'utilisation
|
|
US8288110B2
(en)
*
|
2006-12-04 |
2012-10-16 |
Perkinelmer Health Sciences, Inc. |
Biomarkers for detecting cancer
|
|
EA200900767A1
(ru)
|
2006-12-07 |
2009-12-30 |
Новартис Аг |
Антагонистические антитела против ephb3
|
|
KR101431856B1
(ko)
|
2007-01-22 |
2014-08-27 |
제넨테크, 인크. |
항체의 고분자전해질 침전 및 정제
|
|
WO2008097497A2
(fr)
|
2007-02-02 |
2008-08-14 |
Adnexus, A Bristol-Myers Squibb R & D Company |
Blocage de voie de vegf
|
|
DK2436781T3
(en)
|
2007-02-22 |
2016-01-11 |
Genentech Inc |
Methods for the detection of inflammatory bowel disease
|
|
KR101812400B1
(ko)
|
2007-04-03 |
2017-12-27 |
옥시레인 유케이 리미티드 |
분자의 글리코실화
|
|
JP5989299B2
(ja)
|
2007-05-30 |
2016-09-07 |
エルパス・インコーポレイテッドLpath, Inc. |
リゾホスファチジン酸結合のための組成物と方法
|
|
US9163091B2
(en)
|
2007-05-30 |
2015-10-20 |
Lpath, Inc. |
Compositions and methods for binding lysophosphatidic acid
|
|
SG10201608952QA
(en)
|
2007-06-07 |
2016-12-29 |
Genentech Inc |
C3b antibodies and methods for the prevention and treatment of complement- associated disorders
|
|
HUE061746T2
(hu)
|
2007-07-09 |
2023-08-28 |
Genentech Inc |
Diszulfidkötés redukciójának megelõzése polipeptidek rekombináns elõállítása során
|
|
RU2511410C3
(ru)
|
2007-07-16 |
2021-06-15 |
Дженентек, Инк. |
АНТИ-CD79b АНТИТЕЛА И ИММУНОКОНЪЮГАТЫ И СПОСОБЫ ИХ ПРИМЕНЕНИЯ
|
|
US9845355B2
(en)
|
2007-07-16 |
2017-12-19 |
Genentech, Inc. |
Humanized anti-CD79b antibodies and immunoconjugates and methods of use
|
|
CN101361968B
(zh)
|
2007-08-06 |
2011-08-03 |
健能隆医药技术(上海)有限公司 |
白介素-22在治疗脂肪肝中的应用
|
|
US8361465B2
(en)
|
2007-10-26 |
2013-01-29 |
Lpath, Inc. |
Use of anti-sphingosine-1-phosphate antibodies in combination with chemotherapeutic agents
|
|
EP3441402A1
(fr)
|
2007-10-30 |
2019-02-13 |
Genentech, Inc. |
Purification d'anticorps par chromatographie à échange de cations
|
|
BRPI0820343A2
(pt)
|
2007-11-08 |
2017-08-22 |
Genentech Inc |
Anticorpos de antifator b e seus usos
|
|
ES2395784T3
(es)
|
2007-11-12 |
2013-02-15 |
Theraclone Sciences, Inc. |
Composiciones y métodos para la terapia y diagnosis de la influenza
|
|
TWI468417B
(zh)
|
2007-11-30 |
2015-01-11 |
Genentech Inc |
抗-vegf抗體
|
|
AR070141A1
(es)
|
2008-01-23 |
2010-03-17 |
Glenmark Pharmaceuticals Sa |
Anticuerpos humanizados especificos para el factor von willebrand
|
|
JP5774312B2
(ja)
|
2008-01-24 |
2015-09-09 |
ノボ・ノルデイスク・エー/エス |
ヒト化抗ヒトnkg2aモノクローナル抗体
|
|
CA2713504A1
(fr)
|
2008-01-31 |
2009-08-13 |
Genentech, Inc. |
Anticorps et immunoconjugues anti-cd79b et leurs procedes d'utilisation
|
|
CN102084002B
(zh)
*
|
2008-03-03 |
2014-09-10 |
Abbvie公司 |
用于转化酵母的方法
|
|
MX2010009885A
(es)
|
2008-03-10 |
2010-11-30 |
Theraclone Sciences Inc |
Composiciones y métodos para la terapia y diagnóstico de citomegalovirus.
|
|
CA2719201A1
(fr)
|
2008-03-28 |
2009-10-01 |
Sea Lane Biotechnologies, Llc. |
Molecules neutralisantes d'antigenes viraux
|
|
SI2279412T1
(sl)
|
2008-04-09 |
2017-10-30 |
Genentech, Inc., |
Novi sestavki in postopki za zdravljenje imunsko povezanih bolezni
|
|
RU2553517C2
(ru)
|
2008-05-06 |
2015-06-20 |
Дженентек, Инк. |
Варианты crig с созревшей аффинностью
|
|
CN102112147B
(zh)
|
2008-06-02 |
2014-05-21 |
达纳-法伯癌症研究所股份有限公司 |
Xbp1、cd138、和cs1肽
|
|
DK3604324T3
(da)
|
2008-08-14 |
2024-04-08 |
Genentech Inc |
Fremgangsmåder til at fjerne en kontaminant under anvendelse af ionbytningskromatografi med forskydning af iboende proteiner
|
|
WO2010034015A2
(fr)
|
2008-09-22 |
2010-03-25 |
The Regents Of The University Of Colorado, A Body Corporate |
Modulation de la voie de complément alternative
|
|
AU2009347206C1
(en)
|
2008-10-20 |
2016-12-08 |
Abbvie Inc. |
Isolation and purification of antibodies using Protein A affinity chromatography
|
|
CN104689316A
(zh)
|
2008-10-22 |
2015-06-10 |
弗·哈夫曼-拉罗切有限公司 |
轴突变性的调节
|
|
US8871202B2
(en)
|
2008-10-24 |
2014-10-28 |
Lpath, Inc. |
Prevention and treatment of pain using antibodies to sphingosine-1-phosphate
|
|
NZ592436A
(en)
|
2008-11-06 |
2012-10-26 |
Glenmark Pharmaceuticals Sa |
Treatment with anti-alpha2 integrin antibodies
|
|
AR074777A1
(es)
|
2008-12-19 |
2011-02-09 |
Glaxo Group Ltd |
Proteinas de union a antigeno
|
|
WO2010078376A2
(fr)
|
2008-12-30 |
2010-07-08 |
Ventana Medical Systems, Inc. |
Anticorps conjugués à un polymère spécifiques de fc et leur utilisation en diagnostic
|
|
BR122021021381B1
(pt)
|
2009-02-03 |
2023-05-16 |
Amunix Pharmaceuticals, Inc |
Método de aprimoramento de uma propriedade de uma proteína biologicamente ativa
|
|
SI3260136T1
(sl)
|
2009-03-17 |
2021-05-31 |
Theraclone Sciences, Inc. |
Humani imunodeficientni virus (HIV)-nevtralizirajoča protitelesa
|
|
TW201038286A
(en)
|
2009-04-01 |
2010-11-01 |
Genentech Inc |
Anti-FcRH5 antibodies and immunoconjugates and methods of use
|
|
US20100297127A1
(en)
|
2009-04-08 |
2010-11-25 |
Ghilardi Nico P |
Use of il-27 antagonists to treat lupus
|
|
CN102459340A
(zh)
|
2009-04-23 |
2012-05-16 |
特罗科隆科学有限公司 |
粒性白血细胞-巨噬细胞菌落-刺激因子(gm-csf)中和抗体
|
|
AU2010249787A1
(en)
|
2009-05-20 |
2011-12-22 |
Theraclone Sciences, Inc. |
Compositions and methods for the therapy and diagnosis of influenza
|
|
DK2440228T3
(en)
|
2009-06-08 |
2018-12-17 |
Amunix Operating Inc |
Glucose regulating polypeptides and methods for their preparation and use
|
|
NZ621868A
(en)
|
2009-06-08 |
2015-10-30 |
Amunix Operating Inc |
Growth hormone polypeptides and methods of making and using same
|
|
CA2766842A1
(fr)
|
2009-07-15 |
2011-01-20 |
Abbott Laboratories |
Augmentation de la production cellulaire par mecanotransduction
|
|
SG178177A1
(en)
|
2009-07-31 |
2012-03-29 |
Genentech Inc |
Inhibition of tumor metastasis using bv8- or g-csf-antagonists
|
|
BR112012004697B8
(pt)
|
2009-09-01 |
2021-05-25 |
Genentech Inc |
método para purificar um polipeptídeo compreendendo uma região ch2/ch3
|
|
US9321823B2
(en)
|
2009-09-02 |
2016-04-26 |
Genentech, Inc. |
Mutant smoothened and methods of using the same
|
|
US8926976B2
(en)
|
2009-09-25 |
2015-01-06 |
Xoma Technology Ltd. |
Modulators
|
|
CA2772945A1
(fr)
|
2009-09-25 |
2011-03-31 |
Xoma Technology Ltd. |
Procedes de criblage
|
|
DK2483399T3
(da)
|
2009-09-29 |
2019-05-13 |
Univ Gent |
Hydrolyse af mannose-1-phospho-6-mannose-binding til phospho-6-mannose
|
|
WO2011047267A1
(fr)
|
2009-10-15 |
2011-04-21 |
Genentech, Inc. |
Facteurs de croissance chimériques des fibroblastes avec spécificité de récepteur modifiée
|
|
NZ599100A
(en)
|
2009-10-20 |
2014-07-25 |
Abbvie Inc |
Isolation and purification of anti-il-13 antibodies using protein a affinity chromatography
|
|
US20120328609A1
(en)
|
2009-10-22 |
2012-12-27 |
Genentech, Inc. |
Modulation of Axon Degeneration
|
|
BR112012009409A2
(pt)
|
2009-10-22 |
2017-02-21 |
Genentech Inc |
método de identificação de uma substância inibidora, molécula antagonista, ácido nucleico isolado, vetor, célula hospedeira, método para fabricar a molécula, composição, artigo de fabricação, método de inibição de uma atividade biológica, método de tratamento de uma condição patológica, método para detectar msp em uma amostra e método para detectar hepsina em uma amostra
|
|
WO2011056497A1
(fr)
|
2009-10-26 |
2011-05-12 |
Genentech, Inc. |
Compositions de récepteur de l'activine de type iib et leurs méthodes d'utilisation
|
|
WO2011056502A1
(fr)
|
2009-10-26 |
2011-05-12 |
Genentech, Inc. |
Compositions du gene recepteur de proteine morphogenetique osseuse type ii et procedes d'utilisation
|
|
WO2011056494A1
(fr)
|
2009-10-26 |
2011-05-12 |
Genentech, Inc. |
Combinaisons d'antagonistes de la kinase-1 du type récepteur de l'activine et d'antagonistes vegfr3
|
|
US20110098862A1
(en)
|
2009-10-27 |
2011-04-28 |
ExxonMobil Research Engineering Company Law Department |
Multi-stage processes and control thereof
|
|
KR20120103587A
(ko)
|
2009-11-12 |
2012-09-19 |
제넨테크, 인크. |
수상돌기 소극 밀도를 증진시키는 방법
|
|
KR20130055555A
(ko)
|
2009-11-19 |
2013-05-28 |
옥시레인 유케이 리미티드 |
효모 스트레인 생성용 포유류 유사 복합 n-글리칸들
|
|
SG10201408598XA
(en)
|
2009-11-30 |
2015-02-27 |
Genentech Inc |
Antibodies for treating and diagnosing tumors expressing slc34a2 (tat211 = seqid2 )
|
|
ES2565208T3
(es)
|
2009-12-11 |
2016-04-01 |
F. Hoffmann-La Roche Ag |
Anticuerpos anti-VEGF-C y métodos de uso de los mismos
|
|
WO2011080050A2
(fr)
|
2009-12-11 |
2011-07-07 |
Novartis Ag |
Molécules de liaison
|
|
SG181496A1
(en)
|
2009-12-18 |
2012-07-30 |
Csl Ltd |
Method of purifying polypeptides
|
|
RU2609658C2
(ru)
|
2009-12-21 |
2017-02-02 |
Дженентек, Инк. |
Состав, содержащий антитело
|
|
AU2010334383B2
(en)
|
2009-12-21 |
2014-10-02 |
Centre Hospitalier Universitaire Vaudois (Chuv) |
Synergic action of a prolyl protease and tripeptidyl proteases
|
|
KR20130028055A
(ko)
|
2010-01-28 |
2013-03-18 |
글락소 그룹 리미티드 |
Cd 127 결합 단백질
|
|
WO2011104604A2
(fr)
|
2010-02-23 |
2011-09-01 |
Glenmark Pharmaceuticals S.A. |
Anticorps anti-intégrine alpha-2 et leurs utilisations
|
|
NZ601293A
(en)
|
2010-02-23 |
2014-10-31 |
Genentech Inc |
Compositions and methods for the diagnosis and treatment of tumor
|
|
UA108227C2
(xx)
|
2010-03-03 |
2015-04-10 |
|
Антигензв'язуючий білок
|
|
MX2012011112A
(es)
|
2010-03-31 |
2012-10-15 |
Boehringer Ingelheim Int |
Anticuerpos anti-cd40.
|
|
EP4450523A3
(fr)
|
2010-04-02 |
2025-03-12 |
Amunix Pharmaceuticals, Inc. |
Protéines de fusion de liaison, conjugués protéine de fusion-médicament de liaison, conjugués xten-médicament et leurs procédés de fabrication et d'utilisation
|
|
WO2011133931A1
(fr)
|
2010-04-22 |
2011-10-27 |
Genentech, Inc. |
Utilisation d'antagonistes d'il-27 pour traiter une maladie intestinale inflammatoire
|
|
RU2636461C2
(ru)
|
2010-05-03 |
2017-11-23 |
Дженентек, Инк. |
Композиции и способы для диагностики и лечения опухоли
|
|
BR112012030197A2
(pt)
|
2010-05-28 |
2015-09-29 |
Genentech Inc |
diminuição do nível de lactato e aumento da produção de poliptídeo por subregulação da expressão de lactato desidrogenase e piruvato desidrogenase cinase.
|
|
AU2011261161A1
(en)
|
2010-06-01 |
2013-01-10 |
Ludwig Institute For Cancer Research Limited |
Antibodies directed to the unprocessed receptor tyrosine kinase c-Met
|
|
UY33421A
(es)
|
2010-06-03 |
2011-12-30 |
Glaxo Wellcome House |
Proteinas de union al antígeno humanizados
|
|
BR112012033121B1
(pt)
|
2010-06-25 |
2019-08-20 |
Institut Pasteur De Lille |
Métodos e composições farmacêuticas para o tratamento de infecções do trato respiratório.
|
|
CN103108887A
(zh)
|
2010-07-22 |
2013-05-15 |
葛兰素史密丝克莱恩生物有限公司 |
新的抗原结合蛋白
|
|
WO2012021786A2
(fr)
|
2010-08-12 |
2012-02-16 |
Theraclone Sciences, Inc. |
Compositions d'anticorps anti-hemagglutinine et ses méthodes d'utilisation
|
|
EP2420250A1
(fr)
|
2010-08-13 |
2012-02-22 |
Universitätsklinikum Münster |
Anticorps anti-syndecan-4
|
|
MX2013001267A
(es)
|
2010-08-13 |
2013-04-10 |
Genentech Inc |
ANTICUERPOS A IL-1ß E EIL-18 PARA TRATAMIENTO DE ENFERMEDAD.
|
|
WO2012027494A1
(fr)
|
2010-08-24 |
2012-03-01 |
Regents Of The University Of Minnesota |
Réactifs bispécifiques de ciblage
|
|
EP2611465A4
(fr)
|
2010-08-31 |
2014-06-04 |
Theraclone Sciences Inc |
Anticorps neutralisants anti-virus de l'immunodéficience humaine (vih)
|
|
CN102380091A
(zh)
|
2010-08-31 |
2012-03-21 |
健能隆医药技术(上海)有限公司 |
白介素-22在治疗病毒性肝炎中的应用
|
|
EP2616481A4
(fr)
|
2010-09-15 |
2014-04-02 |
Aligna Technologies Inc |
Production biologique de produits chimiques aromatiques à partir de composés dérivés de lignine
|
|
CA2810909A1
(fr)
|
2010-09-20 |
2012-03-29 |
Abbvie Inc. |
Purification d'anticorps par chromatographie a lit mobile simule
|
|
KR101979220B1
(ko)
|
2010-09-29 |
2019-05-16 |
옥시레인 유케이 리미티드 |
인산화된 n-글리칸들의 탈-만노실화
|
|
EP2622088A2
(fr)
|
2010-09-29 |
2013-08-07 |
Oxyrane UK Limited |
Mannosidases capables d'éliminer la coiffe des liaisons mannose-1-phospho- 6-mannose et de démannosyler les n-glycanes phosphorylés, et méthodes facilitant l'assimilation des glycoprotéines par des cellules de mammifères
|
|
JP5974012B2
(ja)
|
2010-10-05 |
2016-08-23 |
ジェネンテック, インコーポレイテッド |
突然変異体スムースンド及びその使用方法
|
|
EP2624852B1
(fr)
|
2010-10-08 |
2016-12-14 |
Shanghai Kexin Biotech Co., Ltd |
Utilisations diagnostiques et thérapeutiques de fragments de la moésine
|
|
KR101571940B1
(ko)
|
2010-10-08 |
2015-11-25 |
상하이 켁신 바이오테크 씨오., 엘티디. |
면역성 혈소판 감소증과 관련된 모에신 단편
|
|
CA2814026C
(fr)
|
2010-10-08 |
2017-07-11 |
Shanghai Kexin Biotech Co., Ltd. |
Fragments de la moesine associes a l'anemie aplasique
|
|
WO2012045274A1
(fr)
|
2010-10-08 |
2012-04-12 |
Shanghai Kexin Biotech Co., Ltd. |
Modulateurs de la moésine et leurs utilisations
|
|
KR101641756B1
(ko)
|
2010-10-08 |
2016-07-21 |
상하이 켁신 바이오테크 씨오., 엘티디. |
모에신 단편 및 그의 용도
|
|
SI2635601T1
(sl)
|
2010-11-04 |
2017-01-31 |
Boehringer Ingelheim International Gmbh |
Anti-il-23-protitelesa
|
|
AU2011338892A1
(en)
|
2010-11-05 |
2013-05-23 |
Abbvie Inc. |
Efficient and effective supplement screening for the development of chemically defined media in cell culture
|
|
WO2012058726A1
(fr)
|
2010-11-05 |
2012-05-10 |
Transbio Ltd |
Marqueurs de cellules progénitrices endothéliales et leurs utilisations
|
|
WO2012064619A1
(fr)
*
|
2010-11-10 |
2012-05-18 |
Merck Sharp & Dohme Corp. |
Locus de pichia pastoris codant pour des enzymes dans la voie biosynthétique de la proline
|
|
US20140199682A1
(en)
|
2010-11-17 |
2014-07-17 |
Sea Lane Biotechnologies, Llc |
Influenza neutralizing agents
|
|
BR112013016235B1
(pt)
|
2010-12-22 |
2020-03-31 |
Cephalon Australia Pty Ltd |
Anticorpo isolado, uso de um anticorpo, ácido nucleico, célula transformada e composição farmacêutica
|
|
CN103687619A
(zh)
|
2011-02-14 |
2014-03-26 |
特罗科隆科学有限公司 |
用于对流行性感冒进行治疗以及诊断的组合物以及方法
|
|
US20140056897A1
(en)
|
2011-03-10 |
2014-02-27 |
Hco Antibody, Inc. |
Bispecific three-chain antibody-like molecules
|
|
WO2012122512A1
(fr)
|
2011-03-10 |
2012-09-13 |
Hco Antibody, Inc. |
Production recombinante de mélanges d'anticorps monocaténaires
|
|
WO2012125735A1
(fr)
|
2011-03-15 |
2012-09-20 |
Abott Laboratories |
Approche intégrée à isolement et purification d'anticorps
|
|
CN103533929A
(zh)
|
2011-03-15 |
2014-01-22 |
特罗科隆科学有限公司 |
用于流行性感冒的治疗和诊断的组合物和方法
|
|
TW201239355A
(en)
|
2011-03-23 |
2012-10-01 |
Abbott Lab |
Methods and systems for the analysis of protein samples
|
|
JP6248029B2
(ja)
|
2011-03-31 |
2017-12-13 |
ジェネンテック, インコーポレイテッド |
ベータ7インテグリンアンタゴニストの投与方法
|
|
EP2702077A2
(fr)
|
2011-04-27 |
2014-03-05 |
AbbVie Inc. |
Procédé de contrôle du profil de galactosylation de protéines exprimées de manière recombinante
|
|
JP6400470B2
(ja)
|
2011-05-16 |
2018-10-03 |
ジェネロン(シャンハイ)コーポレイション リミテッド |
多重特異性Fab融合タンパク質および使用法
|
|
AU2012261933B2
(en)
|
2011-06-03 |
2017-06-15 |
Xoma Technology Ltd. |
Antibodies specific for TGF-beta
|
|
JP2013040160A
(ja)
|
2011-07-01 |
2013-02-28 |
Genentech Inc |
自己免疫疾患を治療するための抗cd83アゴニスト抗体の使用
|
|
KR20200067220A
(ko)
|
2011-07-11 |
2020-06-11 |
아이크노스 사이언스 에스. 아. |
Ox40에 결합하는 항체 및 이들의 용도
|
|
MX2014001736A
(es)
|
2011-08-17 |
2014-03-31 |
Genentech Inc |
Inhibicion de angiogenesis en tumores refractarios.
|
|
US8822651B2
(en)
|
2011-08-30 |
2014-09-02 |
Theraclone Sciences, Inc. |
Human rhinovirus (HRV) antibodies
|
|
WO2013041687A1
(fr)
|
2011-09-23 |
2013-03-28 |
Amgen Research (Munich) Gmbh |
Molécules de liaison bispécifiques pour 5t4 et cd3
|
|
TWI679212B
(zh)
|
2011-11-15 |
2019-12-11 |
美商安進股份有限公司 |
針對bcma之e3以及cd3的結合分子
|
|
CN118515766A
(zh)
|
2011-11-16 |
2024-08-20 |
勃林格殷格翰国际有限公司 |
抗il-36r抗体
|
|
CA2857168C
(fr)
|
2011-12-01 |
2020-10-27 |
Protevobio, Inc. |
Inhibiteurs proteiques du complement et des voies du vegf, et procedes d'utilisation associes
|
|
CN112877370A
(zh)
|
2011-12-16 |
2021-06-01 |
布拉斯科南美公司 |
经修饰的微生物和使用其制造丁二烯的方法
|
|
WO2013091903A1
(fr)
|
2011-12-22 |
2013-06-27 |
Novo Nordisk A/S |
Anticorps anti-canal crac
|
|
ES2697676T3
(es)
|
2011-12-22 |
2019-01-25 |
Hoffmann La Roche |
Cromatografía de membrana de intercambio iónico
|
|
BR112014015933A2
(pt)
|
2011-12-30 |
2019-09-24 |
Oxyrane Uk Ltd |
métodos e materiais para reduzir a degradação das proteínas recombinantes
|
|
KR20140117565A
(ko)
|
2012-01-19 |
2014-10-07 |
유니버시티 오브 신시내티 |
비글리코실화 아포리포단백질 a-iv를 이용하여 당뇨병을 치료하는 방법
|
|
SG11201404486QA
(en)
|
2012-01-31 |
2014-11-27 |
Genentech Inc |
Anti-ig-e m1' antibodies and methods using same
|
|
US20150037334A1
(en)
|
2012-03-01 |
2015-02-05 |
Amgen Research (Munich) Gmbh |
Long life polypeptide binding molecules
|
|
AU2013234042B2
(en)
|
2012-03-15 |
2017-11-02 |
Oxyrane Uk Limited |
Methods and materials for treatment of Pompe's disease
|
|
US9334319B2
(en)
|
2012-04-20 |
2016-05-10 |
Abbvie Inc. |
Low acidic species compositions
|
|
US9181572B2
(en)
|
2012-04-20 |
2015-11-10 |
Abbvie, Inc. |
Methods to modulate lysine variant distribution
|
|
WO2013158275A1
(fr)
|
2012-04-20 |
2013-10-24 |
Abbvie Inc. |
Procédés de culture cellulaire pour réduire des espèces acides
|
|
US9550818B2
(en)
|
2012-04-27 |
2017-01-24 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Methods for use of vascular endothelial growth factor antagonists
|
|
EP4039275A1
(fr)
|
2012-05-03 |
2022-08-10 |
Boehringer Ingelheim International GmbH |
Anticorps anti-il-23p19
|
|
TW201348246A
(zh)
|
2012-05-21 |
2013-12-01 |
Abbvie Inc |
利用蛋白質a親和性層析之人類、人類化或嵌合抗體之新穎純化
|
|
US9249182B2
(en)
|
2012-05-24 |
2016-02-02 |
Abbvie, Inc. |
Purification of antibodies using hydrophobic interaction chromatography
|
|
JP2015524808A
(ja)
|
2012-07-25 |
2015-08-27 |
ユニバーシティ・オブ・シンシナティ |
アポリポタンパク質aivを用いたi型糖尿病の治療法
|
|
AU2012385960B2
(en)
|
2012-07-25 |
2017-04-13 |
University Of Cincinnati |
Method of treating hyperglycemic disorders using apolipoprotein AIV
|
|
US9376489B2
(en)
|
2012-09-07 |
2016-06-28 |
Novartis Ag |
IL-18 binding molecules
|
|
EP3919069A1
(fr)
|
2012-11-05 |
2021-12-08 |
Dana-Farber Cancer Institute, Inc. |
Peptides xbp1, cd138 et cs1, compositions pharmaceutiques qui comprennent les peptides et procédés d'utilisation de tels peptides et compositions
|
|
ES2689080T3
(es)
|
2013-01-02 |
2018-11-08 |
Glenmark Pharmaceuticals S.A. |
Anticuerpos que se unen a TL1A y sus usos
|
|
ES2728936T3
(es)
|
2013-01-25 |
2019-10-29 |
Amgen Inc |
Anticuerpos dirigidos contra CDH19 para melanoma
|
|
JO3519B1
(ar)
|
2013-01-25 |
2020-07-05 |
Amgen Inc |
تركيبات أجسام مضادة لأجل cdh19 و cd3
|
|
WO2014136065A2
(fr)
|
2013-03-05 |
2014-09-12 |
Oxyrane Uk Limited |
Production de sulfatase de type i catalytiquement active
|
|
PL2968466T3
(pl)
|
2013-03-13 |
2018-11-30 |
F.Hoffmann-La Roche Ag |
Preparaty o zmniejszonym utlenianiu
|
|
US20140314778A1
(en)
|
2013-03-13 |
2014-10-23 |
Genentech, Inc. |
Formulations with reduced oxidation
|
|
PT2968467T
(pt)
|
2013-03-13 |
2020-07-28 |
Hoffmann La Roche |
Formulações de oxidação reduzida
|
|
US10653779B2
(en)
|
2013-03-13 |
2020-05-19 |
Genentech, Inc. |
Formulations with reduced oxidation
|
|
RU2694055C2
(ru)
|
2013-03-13 |
2019-07-09 |
Дженентек, Инк. |
Составы антител
|
|
WO2014151901A1
(fr)
|
2013-03-14 |
2014-09-25 |
Abbvie Inc. |
Amélioration de la performance de la culture de cellules de mammifère au moyen d'une supplémentation de milieux d'alimentation en tensioactifs
|
|
HK1206755A1
(en)
|
2013-03-14 |
2016-01-15 |
Abbvie Inc. |
Low acidic species compositions and methods for producing and using the same
|
|
EP2970375A1
(fr)
|
2013-03-14 |
2016-01-20 |
AbbVie Inc. |
Composition d'espèces faiblement acides et leurs méthodes de production utilisant la chromatographie de déplacement
|
|
WO2014142882A1
(fr)
|
2013-03-14 |
2014-09-18 |
Abbvie Inc. |
Purification de protéine utilisant une chromatographie de déplacement
|
|
EP2970446A1
(fr)
|
2013-03-15 |
2016-01-20 |
Amgen Research (Munich) GmbH |
Constructions d'anticorps pour m2 et cd3 de grippe
|
|
AR095348A1
(es)
|
2013-03-15 |
2015-10-07 |
Genentech Inc |
Medios de cultivo celular y métodos de producción de anticuerpos
|
|
US20140283157A1
(en)
|
2013-03-15 |
2014-09-18 |
Diadexus, Inc. |
Lipoprotein-associated phospholipase a2 antibody compositions and methods of use
|
|
AR095374A1
(es)
|
2013-03-15 |
2015-10-14 |
Amgen Res Munich Gmbh |
Moléculas de unión para bcma y cd3
|
|
US20160122436A1
(en)
|
2013-03-15 |
2016-05-05 |
Amgen Research (Munich) Gmbh |
Single chain binding molecules comprising n-terminal abp
|
|
PT3611180T
(pt)
|
2013-03-15 |
2022-03-15 |
Biomolecular Holdings Llc |
Imunoglobulina híbrida que contém uma ligação não peptídica
|
|
AU2014233393B2
(en)
|
2013-03-15 |
2020-05-28 |
Genentech, Inc. |
Cell culture compositions with antioxidants and methods for polypeptide production
|
|
JP6574754B2
(ja)
|
2013-03-19 |
2019-09-11 |
ベイジン シェノゲン ファーマ グループ リミテッド |
エストロゲン受容体関連疾患を処置するための抗体及び方法
|
|
WO2014160753A1
(fr)
|
2013-03-27 |
2014-10-02 |
Genentech, Inc. |
Utilisation de biomarqueurs pour évaluer le traitement de troubles gastro-intestinaux inflammatoires par des antagonistes de l'intégrine bêta7
|
|
LT3004162T
(lt)
|
2013-05-31 |
2020-06-10 |
Genentech, Inc. |
Antikūnai prieš ląstelės sienelės teicho rūgštį ir konjugatai
|
|
CN105308067B
(zh)
|
2013-06-07 |
2020-07-24 |
诺和诺德股份有限公司 |
制备成熟胰岛素多肽的方法
|
|
TWI688401B
(zh)
|
2013-09-13 |
2020-03-21 |
美商安進公司 |
用於治療骨髓性白血病的表觀遺傳因子與靶向cd33及cd3之雙特異性化合物的組合
|
|
CA2925310C
(fr)
|
2013-09-27 |
2022-12-06 |
Genentech, Inc. |
Formulations d'anticorps anti-pdl1
|
|
US10203327B2
(en)
|
2013-11-05 |
2019-02-12 |
Novartis Ag |
Organic compounds
|
|
CN104623637A
(zh)
|
2013-11-07 |
2015-05-20 |
健能隆医药技术(上海)有限公司 |
Il-22二聚体在制备静脉注射药物中的应用
|
|
EP3647324A1
(fr)
|
2013-12-17 |
2020-05-06 |
F. Hoffmann-La Roche AG |
Procédés de traitement de cancers au moyen d'antagonistes de liaison d'axe pd-1 et de taxanes
|
|
WO2015095423A2
(fr)
|
2013-12-17 |
2015-06-25 |
Genentech, Inc. |
Polythérapie comprenant des agonistes se liant à ox40 et des antagonistes se liant à l'axe pd-1
|
|
SG11201604875PA
(en)
|
2013-12-17 |
2016-07-28 |
Genentech Inc |
Methods of treating cancer using pd-1 axis binding antagonists and an anti-cd20 antibody
|
|
WO2015102341A1
(fr)
|
2013-12-30 |
2015-07-09 |
재단법인 의약바이오컨버젼스연구단 |
Anticorps monoclonal anti-krs et son utilisation
|
|
CA2934965A1
(fr)
|
2014-01-31 |
2016-03-17 |
Boehringer Ingelheim International Gmbh |
Nouveaux anticorps anti-baff
|
|
WO2015116902A1
(fr)
|
2014-01-31 |
2015-08-06 |
Genentech, Inc. |
Récepteurs couplés aux protéines g dans la signalisation hedgehog
|
|
JP6736467B2
(ja)
|
2014-02-04 |
2020-08-05 |
ジェネンテック, インコーポレイテッド |
平滑化変異体及びその使用方法
|
|
NZ724904A
(en)
|
2014-03-14 |
2023-04-28 |
Biomolecular Holdings Llc |
Hybrid immunoglobulin containing non-peptidyl linkage
|
|
CN111808276A
(zh)
|
2014-03-25 |
2020-10-23 |
豪夫迈·罗氏有限公司 |
制备用于细胞培养基中的泊洛沙姆的方法
|
|
BR112016020053A2
(pt)
|
2014-03-27 |
2018-02-20 |
Genentech, Inc. |
métodos de previsão da reação de pacientes que sofrem de distúrbio inflamatório, de previsão da capacidade de reação de pacientes, de identificação de pacientes que sofrem de distúrbio inflamatório e de seu tratamento, usos de kit e kits
|
|
KR20160146747A
(ko)
|
2014-03-31 |
2016-12-21 |
제넨테크, 인크. |
항혈관신생제 및 ox40 결합 효능제를 포함하는 조합 요법
|
|
US8961992B1
(en)
|
2014-04-02 |
2015-02-24 |
Tunitas Therapeutics, Inc. |
Epsigam fusion protein
|
|
EP3149187B1
(fr)
|
2014-05-30 |
2020-04-29 |
Braskem S.A. |
Micro-organismes modifiés comprenant un système optimisé pour l'utilisation d'oligosaccharides et procédés pour les utiliser
|
|
EP3145951A1
(fr)
|
2014-06-24 |
2017-03-29 |
InSight Biopharmaceuticals Ltd. |
Procédés de purification d'anticorps
|
|
US20170226552A1
(en)
|
2014-07-03 |
2017-08-10 |
Abbvie Inc. |
Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using cobalt
|
|
US20160185848A1
(en)
|
2014-07-09 |
2016-06-30 |
Abbvie Inc. |
Methods for modulating the glycosylation profile of recombinant proteins using sugars
|
|
JP2017524359A
(ja)
|
2014-07-24 |
2017-08-31 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Il−23a関連疾患の処置に有用なバイオマーカー
|
|
UY36245A
(es)
|
2014-07-31 |
2016-01-29 |
Amgen Res Munich Gmbh |
Constructos de anticuerpos para cdh19 y cd3
|
|
MX377344B
(es)
|
2014-07-31 |
2025-03-07 |
Amgen Res Munich Gmbh |
Constructos de anticuerpos de cadena sencilla biespecífica específicos para especies cruzadas optimizadas.
|
|
ES2980787T3
(es)
|
2014-07-31 |
2024-10-03 |
Amgen Res Munich Gmbh |
Constructo de anticuerpo de cadena sencilla biespecífico con distribución tisular potenciada
|
|
EP3193932B1
(fr)
|
2014-09-15 |
2023-04-26 |
F. Hoffmann-La Roche AG |
Formulations d'anticorps
|
|
WO2016059602A2
(fr)
|
2014-10-16 |
2016-04-21 |
Glaxo Group Limited |
Méthodes de traitement du cancer et compositions associées
|
|
BR112017010198A2
(pt)
|
2014-11-17 |
2017-12-26 |
Genentech Inc |
terapia de combinação compreendendo agonistas de ligação a ox40 e antagonistas de ligação ao eixo de pd-1
|
|
HK1243931A1
(zh)
|
2014-12-03 |
2018-07-27 |
F. Hoffmann-La Roche Ag |
抗金黄色葡萄球菌抗体利福霉素缀合物及其用途
|
|
WO2016120764A1
(fr)
|
2015-01-26 |
2016-08-04 |
Centre Hospitalier Universitaire Vaudois (Chuv) |
Prolyl-endopeptidases d'aspergillus oryzae et utilisation associée dans la dégradation de polypeptides
|
|
HK1244512A1
(zh)
|
2015-02-04 |
2018-08-10 |
健泰科生物技术公司 |
突变型smoothened及其使用方法
|
|
WO2016126638A1
(fr)
|
2015-02-04 |
2016-08-11 |
Boehringer Ingelheim International Gmbh |
Méthodes de traitement de maladies inflammatoires
|
|
CN113209289A
(zh)
|
2015-02-26 |
2021-08-06 |
豪夫迈·罗氏有限公司 |
治疗Crohn病的整联蛋白β7拮抗剂和方法
|
|
WO2016141111A1
(fr)
|
2015-03-03 |
2016-09-09 |
Xoma (Us) Llc |
Traitement d'une hyperinsulinémie post-prandiale et d'une hypoglycémie après chirurgie bariatrique
|
|
WO2016144773A1
(fr)
|
2015-03-06 |
2016-09-15 |
Abbvie Inc. |
Glycoprotéines arabinosylées
|
|
EP3277716B1
(fr)
|
2015-04-03 |
2020-06-24 |
XOMA Technology Ltd. |
Traitement du cancer à l'aide d'inhibiteurs de tgf-bêta et pd-1
|
|
WO2016168282A1
(fr)
|
2015-04-14 |
2016-10-20 |
Boehringer Ingelheim International Gmbh |
Méthodes de traitement de maladies
|
|
JP6907124B2
(ja)
|
2015-04-17 |
2021-07-21 |
アムゲン リサーチ (ミュンヘン) ゲーエムベーハーAMGEN Research(Munich)GmbH |
Cdh3及びcd3に対する二重特異性抗体構築物
|
|
PL3303619T3
(pl)
|
2015-05-29 |
2020-10-05 |
F. Hoffmann-La Roche Ag |
Metylacja promotora PD-L1 w chorobach nowotworowych
|
|
KR102689256B1
(ko)
|
2015-06-17 |
2024-07-30 |
제넨테크, 인크. |
Pd-1 축 결합 길항제 및 탁산을 사용하여 국소적 진행성 또는 전이성 유방암을 치료하는 방법
|
|
TWI796283B
(zh)
|
2015-07-31 |
2023-03-21 |
德商安美基研究(慕尼黑)公司 |
Msln及cd3抗體構築體
|
|
TWI829617B
(zh)
|
2015-07-31 |
2024-01-21 |
德商安美基研究(慕尼黑)公司 |
Flt3及cd3抗體構築體
|
|
TWI717375B
(zh)
|
2015-07-31 |
2021-02-01 |
德商安美基研究(慕尼黑)公司 |
Cd70及cd3抗體構築體
|
|
TW202346349A
(zh)
|
2015-07-31 |
2023-12-01 |
德商安美基研究(慕尼黑)公司 |
Dll3及cd3抗體構築體
|
|
EA039859B1
(ru)
|
2015-07-31 |
2022-03-21 |
Эмджен Рисерч (Мюник) Гмбх |
Биспецифические конструкты антител, связывающие egfrviii и cd3
|
|
TWI744242B
(zh)
|
2015-07-31 |
2021-11-01 |
德商安美基研究(慕尼黑)公司 |
Egfrviii及cd3抗體構築體
|
|
TWI797060B
(zh)
|
2015-08-04 |
2023-04-01 |
美商再生元醫藥公司 |
補充牛磺酸之細胞培養基及用法
|
|
PL3334763T3
(pl)
|
2015-08-11 |
2024-12-02 |
WuXi Biologics Ireland Limited |
Nowe przeciwciała anty-pd-1
|
|
CN108026160A
(zh)
|
2015-09-07 |
2018-05-11 |
德国亥姆霍兹慕尼黑中心健康与环境研究中心(有限公司) |
新型igfr-样受体及其用途
|
|
TWI811716B
(zh)
|
2015-09-18 |
2023-08-11 |
德商百靈佳殷格翰國際股份有限公司 |
治療發炎性疾病之方法
|
|
JP6956417B2
(ja)
|
2015-12-24 |
2021-11-02 |
オキシレイン ユーケー リミテッド |
ヒトα−N−アセチルガラクトサミニダーゼポリペプチド
|
|
IL299759A
(en)
|
2015-12-30 |
2023-03-01 |
Genentech Inc |
Formulations with reduced polysorbate dissolution
|
|
CA3007491A1
(fr)
|
2015-12-30 |
2017-07-06 |
Genentech, Inc. |
Utilisation de derives du tryptophane pour formulations proteiques
|
|
PT3411402T
(pt)
|
2016-02-03 |
2022-02-01 |
Amgen Inc |
Construtos de anticorpos biespecíficos engajadores de células t contra bcma e cd3
|
|
TN2018000266A1
(en)
|
2016-02-03 |
2020-01-16 |
Amgen Res Munich Gmbh |
Psma and cd3 bispecific t cell engaging antibody constructs.
|
|
AU2017213826A1
(en)
|
2016-02-04 |
2018-08-23 |
Curis, Inc. |
Mutant smoothened and methods of using the same
|
|
PL3430054T3
(pl)
|
2016-03-15 |
2022-05-23 |
Chugai Seiyaku Kabushiki Kaisha |
Sposoby leczenia nowotworów z zastosowaniem antagonistów wiązania z osią PD-1 i przeciwciał anty-GPC3
|
|
CN109476756B
(zh)
|
2016-03-15 |
2022-05-31 |
埃泰美德(香港)有限公司 |
一种多特异性Fab融合蛋白及其用途
|
|
RU2744959C2
(ru)
|
2016-03-23 |
2021-03-17 |
Мэбспейс Байосайнсиз (Сучжоу) Ко., Лтд |
Новые анти-pd-l1 антитела
|
|
US11510966B2
(en)
|
2016-04-15 |
2022-11-29 |
Evive Biotechnology (Shanghai) Ltd |
Use of IL-22 in treating necrotizing enterocolitis
|
|
JP6728392B2
(ja)
|
2016-04-15 |
2020-07-22 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
炎症性疾患の処置法
|
|
EP3464354B1
(fr)
|
2016-06-02 |
2021-07-28 |
Bloom Diagnostics AG |
Anticorps se liant à une hormone anti-müllérienne (amh) humaine et leurs utilisations
|
|
CN118530358A
(zh)
|
2016-08-01 |
2024-08-23 |
佐马美国有限公司 |
甲状旁腺激素受体1(pth1r)抗体和其用途
|
|
CN109476748B
(zh)
|
2016-08-08 |
2023-05-23 |
豪夫迈·罗氏有限公司 |
用于癌症的治疗和诊断方法
|
|
JP2020502991A
(ja)
|
2016-09-20 |
2020-01-30 |
ウーシー バイオロジクス アイルランド リミテッド |
新規抗pcsk9抗体
|
|
CN110087681A
(zh)
|
2016-09-28 |
2019-08-02 |
佐马美国有限公司 |
结合白细胞介素-2的抗体和其用途
|
|
EP3526252A2
(fr)
|
2016-10-14 |
2019-08-21 |
Boehringer Ingelheim International GmbH |
Méthodes de traitement de maladies avec anticorps il-23a
|
|
EP3526248A4
(fr)
|
2016-10-17 |
2020-07-08 |
Musc Foundation for Research Development |
Compositions et méthodes de traitement d'une lésion du système nerveux central
|
|
US20190352374A1
(en)
|
2017-01-30 |
2019-11-21 |
Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) |
Novel igfr_like 2 receptor and uses thereof
|
|
EP4620975A3
(fr)
|
2017-02-02 |
2025-12-24 |
Amgen Research (Munich) GmbH |
Composition pharmaceutique à ph bas comprenant des constructions d'anticorps entrant en contact avec des lymphocytes t
|
|
WO2018152496A1
(fr)
|
2017-02-17 |
2018-08-23 |
The Usa, As Represented By The Secretary, Dept. Of Health And Human Services |
Compositions et méthodes de diagnostic et de traitement de l'infection par le virus zika
|
|
EP3596126A4
(fr)
|
2017-03-15 |
2021-03-03 |
Tsinghua University |
Nouveaux anticorps anti-trkb
|
|
CN110461877A
(zh)
|
2017-03-27 |
2019-11-15 |
勃林格殷格翰国际有限公司 |
抗il-36r抗体联合治疗
|
|
WO2018182284A1
(fr)
|
2017-03-27 |
2018-10-04 |
재단법인 의약바이오컨버젼스연구단 |
Anticorps se liant spécifiquement à la région n-terminale de la lysyl-arnt synthétase exposée sur une membrane cellulaire
|
|
EP3615569A1
(fr)
|
2017-04-25 |
2020-03-04 |
The U.S.A. As Represented By The Secretary, Department Of Health And Human Services |
Anticorps et procédés de diagnostic et de traitement d'infection par le virus d'epstein barr
|
|
AR111773A1
(es)
|
2017-05-05 |
2019-08-21 |
Amgen Inc |
Composición farmacéutica que comprende constructos de anticuerpos biespecíficos para almacenamiento y administración
|
|
US10793634B2
(en)
|
2017-06-09 |
2020-10-06 |
Boehringer Ingelheim International Gmbh |
Anti-TrkB antibodies
|
|
EP3655430A1
(fr)
|
2017-07-19 |
2020-05-27 |
The U.S.A. as represented by the Secretary, Department of Health and Human Services |
Anticorps et procédés de diagnostic et de traitement d'infection par le virus de l'hépatite b
|
|
US11517591B2
(en)
|
2017-09-01 |
2022-12-06 |
Dana-Farber Cancer Institute, Inc. |
Immunogenic peptides specific to BCMA and TACI antigens
|
|
CN109535257B
(zh)
|
2017-09-22 |
2021-05-28 |
同润生物医药(上海)有限公司 |
新型双特异性cd3/cd19多肽复合物
|
|
US11339221B2
(en)
|
2017-11-01 |
2022-05-24 |
Tufts Medical Center, Inc. |
Bispecific antibody constructs and methods of use
|
|
IL275054B2
(en)
|
2017-12-11 |
2025-11-01 |
Amgen Inc |
Continuous manufacturing process for bispecific antibody products
|
|
UY38041A
(es)
|
2017-12-29 |
2019-06-28 |
Amgen Inc |
Construcción de anticuerpo biespecífico dirigida a muc17 y cd3
|
|
EP3755718A1
(fr)
|
2018-02-21 |
2020-12-30 |
Celgene Corporation |
Anticorps de liaison à bcma et leurs utilisations
|
|
EP3768725A4
(fr)
|
2018-03-20 |
2021-06-02 |
Wuxi Biologics Ireland Limited |
Nouveaux anticorps anti-tim-3
|
|
KR102340989B1
(ko)
|
2018-03-28 |
2021-12-20 |
에이비온 주식회사 |
클라우딘 3의 ecl-2에 특이적으로 결합하는 항체, 이의 단편 및 이들의 용도
|
|
WO2019195561A2
(fr)
|
2018-04-06 |
2019-10-10 |
BioLegend, Inc. |
Agents anti-tétraspanine 33 et compositions et procédés pour la fabrication et l'utilisation de ces agents
|
|
WO2019213416A1
(fr)
|
2018-05-02 |
2019-11-07 |
The Usa, As Represented By The Secretary, Dept. Of Health And Human Services |
Anticorps et méthodes de diagnostic, de prévention et de traitement d'infection par le virus d'epstein barr
|
|
TWI890148B
(zh)
|
2018-06-23 |
2025-07-11 |
美商建南德克公司 |
以pd-1軸結合拮抗劑、鉑劑及拓撲異構酶ii抑制劑治療肺癌之方法
|
|
EA202190094A1
(ru)
|
2018-06-29 |
2021-04-21 |
Бёрингер Ингельхайм Интернациональ Гмбх |
Антитела против cd40 для применения в лечении аутоиммунного заболевания
|
|
WO2020033485A1
(fr)
|
2018-08-08 |
2020-02-13 |
Genentech, Inc. |
Utilisation de dérivés du tryptophane pour de l-méthionine pour une formulation protéique
|
|
CN112867735B
(zh)
|
2018-09-07 |
2025-05-09 |
埃泰美德(香港)有限公司 |
双特异性抗原结合蛋白及其用途
|
|
KR102739487B1
(ko)
|
2018-09-21 |
2024-12-10 |
제넨테크, 인크. |
3중-음성 유방암에 대한 진단 방법
|
|
WO2020068557A1
(fr)
|
2018-09-25 |
2020-04-02 |
BioLegend, Inc. |
Agents anti-tlr9 et compositions et procédés pour les préparer et les utiliser
|
|
US11505614B2
(en)
|
2018-09-28 |
2022-11-22 |
Amgen Inc. |
Antibodies binding to soluble BCMA
|
|
CN112789058A
(zh)
|
2018-10-11 |
2021-05-11 |
安进公司 |
双特异性抗体构建体的下游加工
|
|
MX2021004684A
(es)
|
2018-10-23 |
2021-06-04 |
Glycardial Diagnostics S L |
Anticuerpos especificos para apoj glucosilada y usos de los mismos.
|
|
WO2020132810A1
(fr)
|
2018-12-24 |
2020-07-02 |
Generon (Shanghai) Corporation Ltd. |
Protéines multispécifiques de liaison à l'antigène pouvant se lier à cd19 et cd3, et leur utilisation
|
|
WO2020136232A1
(fr)
|
2018-12-28 |
2020-07-02 |
Transgene Sa |
Protéine m2 à propriété immunosuppressive
|
|
EP3941938A1
(fr)
|
2019-03-06 |
2022-01-26 |
Dana-Farber Cancer Institute, Inc. |
Récepteurs de lymphocytes t spécifiques de l'antigène de maturation des lymphocytes b pour le traitement du cancer
|
|
AU2020248645A1
(en)
|
2019-03-27 |
2021-10-28 |
Tigatx, Inc. |
Engineered IgA antibodies and methods of use
|
|
MY206253A
(en)
|
2019-05-09 |
2024-12-05 |
Boehringer Ingelheim Int |
Anti-sema3a antibodies and their uses for treating eye or ocular diseases
|
|
CA3141504A1
(fr)
|
2019-05-24 |
2020-12-03 |
Sanyou Biopharmaceuticals Co., Ltd. |
Nouvelle molecule de liaison cldn18.2
|
|
TWI877179B
(zh)
|
2019-06-27 |
2025-03-21 |
德商百靈佳殷格翰國際股份有限公司 |
抗-angpt2抗體
|
|
CA3152665A1
(fr)
|
2019-08-27 |
2021-03-04 |
Tonix Pharma Limited |
Polypeptides tff2 modifies
|
|
TW202535466A
(zh)
|
2019-09-09 |
2025-09-16 |
德商百靈佳殷格翰國際股份有限公司 |
抗-il-23p19抗體調配物
|
|
US20220306741A1
(en)
|
2019-09-10 |
2022-09-29 |
Amgen Inc. |
Purification Method for Bispecific antigen-binding Polypeptides with Enhanced Protein L Capture Dynamic Binding Capacity
|
|
US20230125690A1
(en)
|
2019-09-20 |
2023-04-27 |
Jae-sung Bae |
Antibody for detecting acetylation of cox2 protein, and uses thereof
|
|
TWI859339B
(zh)
|
2019-09-24 |
2024-10-21 |
德商百靈佳殷格翰國際股份有限公司 |
抗nrp1a抗體及其用於治療眼或眼部疾病之用途
|
|
US12297451B1
(en)
|
2019-10-25 |
2025-05-13 |
Regeneron Pharmaceuticals, Inc. |
Cell culture medium
|
|
AU2020381536A1
(en)
|
2019-11-13 |
2022-04-21 |
Amgen Inc. |
Method for reduced aggregate formation in downstream processing of bispecific antigen-binding molecules
|
|
EP4093771A1
(fr)
|
2020-01-22 |
2022-11-30 |
Amgen Research (Munich) GmbH |
Combinaisons de constructions d'anticorps et d'inhibiteurs du syndrome de libération de cytokine et leurs utilisations
|
|
CN115551894A
(zh)
|
2020-03-12 |
2022-12-30 |
以明生物免疫医疗公司 |
新型抗lilrb4抗体和衍生产物
|
|
EP4121459A1
(fr)
|
2020-03-19 |
2023-01-25 |
Amgen Inc. |
Anticorps contre la mucine 17 et leurs utilisations
|
|
CN113461817B
(zh)
|
2020-03-31 |
2025-04-18 |
苏州泽璟生物制药股份有限公司 |
一种抗人cd47抗体及其抗原结合片段、制备方法和应用
|
|
HUE073185T2
(hu)
|
2020-04-15 |
2026-01-28 |
Genentech Inc |
Rézveszteség csökkentés
|
|
AU2021275049A1
(en)
|
2020-05-19 |
2022-12-22 |
Amgen Inc. |
MAGEB2 binding constructs
|
|
KR102871588B1
(ko)
|
2020-05-26 |
2025-10-17 |
베링거 인겔하임 인터내셔날 게엠베하 |
항-pd-1 항체
|
|
KR20230019152A
(ko)
|
2020-06-02 |
2023-02-07 |
아르커스 바이오사이언시즈 인코포레이티드 |
Tigit에 대한 항체
|
|
WO2021257497A1
(fr)
|
2020-06-15 |
2021-12-23 |
Sarepta Therapeutis, Inc. |
Anticorps anti-virus adéno-associés et fragments de ceux-ci
|
|
JP2023531406A
(ja)
|
2020-06-16 |
2023-07-24 |
ジェネンテック, インコーポレイテッド |
トリプルネガティブ乳がんを処置するための方法および組成物
|
|
EP3939999A1
(fr)
|
2020-07-14 |
2022-01-19 |
Fundación del Sector Público Estatal Centro Nacional de Investigaciones Oncológicas Carlos III (F.S.P. CNIO) |
Anticorps neutralisant la sous-unité alpha du récepteur de l'interleukine 11 (il11ra) et leurs utilisations
|
|
WO2022093640A1
(fr)
|
2020-10-30 |
2022-05-05 |
BioLegend, Inc. |
Agents anti-nkg2c et compositions et méthodes de production et d'utilisation de ceux-ci
|
|
WO2022093641A1
(fr)
|
2020-10-30 |
2022-05-05 |
BioLegend, Inc. |
Agents anti-nkg2a et compositions et méthodes de production et d'utilisation de ceux-ci
|
|
CA3199931A1
(fr)
|
2020-11-06 |
2022-05-12 |
Amgen Inc. |
Constructions polypeptidiques se liant a cd3
|
|
US20230406887A1
(en)
|
2020-11-06 |
2023-12-21 |
Amegen Inc. |
Antigen binding domain with reduced clipping rate
|
|
IL302586A
(en)
|
2020-11-06 |
2023-07-01 |
Amgen Res Munich Gmbh |
Polypeptide constructs selectively binding to cldn6 and cd3
|
|
CN112480248B
(zh)
|
2020-11-24 |
2023-05-05 |
三优生物医药(上海)有限公司 |
与cld18a2特异性结合的分子
|
|
WO2022133191A2
(fr)
|
2020-12-18 |
2022-06-23 |
Kiniksa Pharmaceuticals, Ltd. |
Compositions de protéines et leurs procédés de production et d'utilisation
|
|
CA3215594A1
(fr)
|
2021-04-02 |
2022-10-06 |
Agnieszka KIELCZEWSKA |
Constructions de liaison a mageb2
|
|
JP2024519523A
(ja)
|
2021-04-26 |
2024-05-15 |
スアンズ バイオファーマシューティカル カンパニー,リミテッド |
二重特異性抗体薬物コンジュゲート
|
|
JP2024529411A
(ja)
|
2021-07-23 |
2024-08-06 |
ヘルムホルツ・ツェントルム・ミュンヘン・ドイチェス・フォーシュンクスツェントルム・フュア・ゲズントハイト・ウント・ウンベルト・ゲーエムベーハー |
Igfr-l1抗体およびその使用
|
|
US20250049939A1
(en)
|
2021-12-10 |
2025-02-13 |
Tubulis Gmbh |
Novel flt3 antibodies and antibody-drug-conjugates based thereon, therapeutic methods and uses thereof in combination with tyrosine kinase inhibitors
|
|
TW202342515A
(zh)
|
2021-12-22 |
2023-11-01 |
瑞士商Cdr生命股份有限公司 |
抗c3抗體及其抗原結合片段及其用於治療眼疾病之用途
|
|
KR20230098953A
(ko)
|
2021-12-27 |
2023-07-04 |
경북대학교 산학협력단 |
Asm에 특이적으로 결합하는 항체 및 이의 용도
|
|
US20250242002A1
(en)
|
2022-01-29 |
2025-07-31 |
Peking University First Hospital |
Truncated forms of iga protease, fusion proteins comprising a truncated form of iga protease and uses thereof
|
|
EP4238988A1
(fr)
|
2022-03-01 |
2023-09-06 |
Consejo Superior De Investigaciones Científicas |
Anticorps dirigés contre le sars-cov-2 et leurs utilisations
|
|
JP2025509274A
(ja)
|
2022-03-09 |
2025-04-11 |
ブリストル-マイヤーズ スクイブ カンパニー |
治療用タンパク質の一過性発現
|
|
WO2024032891A1
(fr)
|
2022-08-11 |
2024-02-15 |
Vib Vzw |
Levure glyco-modifiée pour la production de protéines thérapeutiques
|
|
KR20250071294A
(ko)
|
2022-08-22 |
2025-05-21 |
압데라 테라퓨틱스 인크. |
Dll3 결합 분자 및 이의 용도
|
|
JP2025533434A
(ja)
|
2022-09-14 |
2025-10-07 |
アムジエン・インコーポレーテツド |
二重特異性分子安定化組成物
|
|
PE20251849A1
(es)
|
2022-10-18 |
2025-07-22 |
Tubulis Gmbh |
Novedosos anticuerpo anti-tpbg y conjugados-anticuerpo-droga basados en el mismo, metodos terapeuticos y usos de los mismos
|
|
CN120166939A
(zh)
|
2022-10-18 |
2025-06-17 |
Tubulis 股份有限公司 |
新型抗napi2b抗体和基于该抗体的抗体-药物-偶联物、治疗方法及其用途
|
|
EP4640715A1
(fr)
|
2022-12-23 |
2025-10-29 |
Chimagen Biosciences, Ltd |
Complexe polypeptidique multi-spécifique ciblant gprc5d
|
|
EP4640708A1
(fr)
|
2022-12-23 |
2025-10-29 |
Chimagen Biosciences, Ltd |
Nouvel anticorps anti-gprc5d
|
|
WO2024243217A1
(fr)
|
2023-05-25 |
2024-11-28 |
BioLegend, Inc. |
Anticorps liant ceacam6 et fragments de liaison à l'antigène de ceux-ci
|
|
UY40797A
(es)
|
2023-06-14 |
2024-12-31 |
Amgen Inc |
Moléculas captadoras de enmascaramiento de células t
|
|
WO2025036848A1
(fr)
|
2023-08-11 |
2025-02-20 |
Wuxi Biologics (Shanghai) Co., Ltd. |
Anticorps anti-muc16 et utilisations
|
|
WO2025043134A1
(fr)
|
2023-08-24 |
2025-02-27 |
Rezolute, Inc. |
Formulations à haute concentration pour anticorps anti-récepteur de l'insuline et leurs utilisations
|
|
WO2025072313A1
(fr)
|
2023-09-27 |
2025-04-03 |
BioLegend, Inc. |
Anticorps anti-gpc4
|
|
TW202523694A
(zh)
|
2023-11-17 |
2025-06-16 |
中國大陸商上海藥明生物技術有限公司 |
抗muc16抗體及其用途
|
|
WO2025144974A1
(fr)
|
2023-12-29 |
2025-07-03 |
Absci Corporation |
Variants de domaine fc pour extension de demi-vie et leurs utilisations
|
|
TW202545992A
(zh)
|
2024-01-23 |
2025-12-01 |
中國大陸商上海藥明生物技術有限公司 |
靶向cd3、cd19及cd20之多特異性抗體及其用途
|
|
WO2025171378A1
(fr)
|
2024-02-09 |
2025-08-14 |
Rezolute, Inc. |
Modulation du récepteur de l'insuline pour hyperinsulinisme associé à une tumeur
|
|
WO2025212738A1
(fr)
|
2024-04-04 |
2025-10-09 |
BioLegend, Inc. |
Anticorps se liant à chi3l1 et leurs fragments de liaison à l'antigène
|
|
WO2025230843A2
(fr)
|
2024-05-01 |
2025-11-06 |
BioLegend, Inc. |
Anticorps se liant au kir et leurs fragments se liant à l'antigène
|
|
EP4653010A1
(fr)
|
2024-05-14 |
2025-11-26 |
35Pharma Inc. |
Variants du récepteur de l'activine de type iib et leurs utilisations
|
|
WO2026006472A2
(fr)
|
2024-06-25 |
2026-01-02 |
Kiniksa Pharmaceuticals, Gmbh |
Compositions d'anticorps il-1r1 et leurs procédés de production et d'utilisation
|
|
WO2026039642A1
(fr)
|
2024-08-16 |
2026-02-19 |
Ardeagen Corporation |
Conjugués d'anticorps anti-mésothéline et leurs procédés d'utilisation
|