NO20002721D0 - Heterocykliske forbindelser for inhibitering av gastrisk syresekresjon, fremgangsmÕter for deres fremstilling og farmasøytiske preparater derav - Google Patents
Heterocykliske forbindelser for inhibitering av gastrisk syresekresjon, fremgangsmÕter for deres fremstilling og farmasøytiske preparater deravInfo
- Publication number
- NO20002721D0 NO20002721D0 NO20002721A NO20002721A NO20002721D0 NO 20002721 D0 NO20002721 D0 NO 20002721D0 NO 20002721 A NO20002721 A NO 20002721A NO 20002721 A NO20002721 A NO 20002721A NO 20002721 D0 NO20002721 D0 NO 20002721D0
- Authority
- NO
- Norway
- Prior art keywords
- inhibition
- preparation
- methods
- pharmaceutical preparations
- heterocyclic compounds
- Prior art date
Links
- 230000027119 gastric acid secretion Effects 0.000 title 1
- 150000002391 heterocyclic compounds Chemical class 0.000 title 1
- 230000005764 inhibitory process Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9704404A SE9704404D0 (sv) | 1997-11-28 | 1997-11-28 | New compounds |
| PCT/SE1998/002091 WO1999028322A1 (en) | 1997-11-28 | 1998-11-18 | Heterocyclic compounds for inhibition of gastric acid secretion, processes for their preparation and pharmaceutical compositions thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20002721D0 true NO20002721D0 (no) | 2000-05-26 |
| NO20002721L NO20002721L (no) | 2000-07-28 |
| NO315704B1 NO315704B1 (no) | 2003-10-13 |
Family
ID=20409181
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20002721A NO315704B1 (no) | 1997-11-28 | 2000-05-26 | Heterocykliske forbindelser for inhibering av mavesyresekresjon, farmasöytiske preparater inneholdende slike forbindelser, fremgangsmåter forderes fremstilling, og deres anvendelse |
Country Status (32)
| Country | Link |
|---|---|
| US (1) | US6518270B1 (no) |
| EP (1) | EP1042324B1 (no) |
| JP (1) | JP2001525322A (no) |
| KR (1) | KR20010032559A (no) |
| CN (1) | CN1142933C (no) |
| AR (1) | AR016972A1 (no) |
| AT (1) | ATE233263T1 (no) |
| AU (1) | AU752187C (no) |
| BR (1) | BR9814755A (no) |
| CA (1) | CA2311798A1 (no) |
| CZ (1) | CZ292349B6 (no) |
| DE (1) | DE69811735T2 (no) |
| DK (1) | DK1042324T3 (no) |
| EE (1) | EE04060B1 (no) |
| ES (1) | ES2191356T3 (no) |
| HU (1) | HUP0100601A3 (no) |
| ID (1) | ID24730A (no) |
| IL (1) | IL136145A0 (no) |
| IS (1) | IS5486A (no) |
| MY (1) | MY121032A (no) |
| NO (1) | NO315704B1 (no) |
| NZ (1) | NZ504355A (no) |
| PL (1) | PL340920A1 (no) |
| PT (1) | PT1042324E (no) |
| RU (1) | RU2241000C2 (no) |
| SE (1) | SE9704404D0 (no) |
| SK (1) | SK283904B6 (no) |
| TR (1) | TR200001530T2 (no) |
| TW (1) | TW515798B (no) |
| UA (1) | UA70932C2 (no) |
| WO (1) | WO1999028322A1 (no) |
| ZA (1) | ZA9810468B (no) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0909323B1 (en) | 1996-01-04 | 2007-02-28 | Novartis Vaccines and Diagnostics, Inc. | Helicobacter pylori bacterioferritin |
| SE9704404D0 (sv) | 1997-11-28 | 1997-11-28 | Astra Ab | New compounds |
| ES2231275T3 (es) | 1999-10-08 | 2005-05-16 | Affinium Pharmaceuticals, Inc. | Inhibidores de fab i. |
| JP4387804B2 (ja) * | 2001-04-06 | 2009-12-24 | アフィニアム・ファーマシューティカルズ・インコーポレイテッド | FabI阻害剤 |
| JP2003119140A (ja) * | 2001-08-08 | 2003-04-23 | Sankyo Co Ltd | ピロロピリダジン化合物を含有する医薬 |
| BR0309398A (pt) * | 2002-04-19 | 2005-02-01 | Cellular Genomics Inc | Composto ou um seu sal, hidrato, solvato, forma cristalina, diastereÈmero, prodroga farmaceuticamente aceitável, ou misturas deles, composição farmacêutica, e, métodos para tratar uma condição envolvida com a cinase em um mamìfero, para tratar câncer, e para identificar uma cinase |
| AU2003270489A1 (en) | 2002-09-09 | 2004-03-29 | Cellular Genomics, Inc. | 6-ARYL-IMIDAZO(1,2-a)PYRAZIN-8-YLAMINES, METHOD OF MAKING, AND METHOD OF USE THEREOF |
| WO2004029058A1 (ja) * | 2002-09-25 | 2004-04-08 | Sankyo Company, Limited | 血中ガストリン濃度上昇の抑制のための医薬組成物 |
| AU2003266621A1 (en) * | 2002-09-25 | 2004-04-19 | Sankyo Company, Limited | Medicinal composition for treatment for or prevention of visceral pain |
| PT1575951E (pt) | 2002-12-06 | 2014-09-15 | Debiopharm Int Sa | Compostos heterocíclicos, métodos para os preparar e sua utilização em terapia |
| US7189723B2 (en) | 2003-02-10 | 2007-03-13 | Cgi Pharmaceuticals, Inc. | Certain 8-heteroaryl-6-phenyl-imidazo[1,2-a]pyrazines as modulators of kinase activity |
| AR043002A1 (es) * | 2003-02-18 | 2005-07-13 | Altana Pharma Ag | Imidazopirazinas 6-substituidos |
| EP1608377B1 (en) * | 2003-03-17 | 2008-10-01 | Affinium Pharmaceuticals, Inc. | Pharmaceutical compositions comprising inhibitors of fab i and further antibiotics |
| US7405295B2 (en) | 2003-06-04 | 2008-07-29 | Cgi Pharmaceuticals, Inc. | Certain imidazo[1,2-a]pyrazin-8-ylamines and method of inhibition of Bruton's tyrosine kinase by such compounds |
| US7393848B2 (en) | 2003-06-30 | 2008-07-01 | Cgi Pharmaceuticals, Inc. | Certain heterocyclic substituted imidazo[1,2-A]pyrazin-8-ylamines and methods of inhibition of Bruton's tyrosine kinase by such compounds |
| WO2005019220A2 (en) | 2003-08-11 | 2005-03-03 | Cellular Genomics Inc. | Substituted imidazo[1,2-a]pyrazines as modulators of kinase activity |
| EP1682133A1 (en) | 2003-11-03 | 2006-07-26 | AstraZeneca AB | Imidazo 1,2-a pyridine derivatives for the treatment of silent gastro-esophageal reflux |
| US8450307B2 (en) * | 2004-06-04 | 2013-05-28 | Affinium Pharmaceuticals, Inc. | Therapeutic agents, and methods of making and using the same |
| JP4977465B2 (ja) * | 2004-07-28 | 2012-07-18 | 武田薬品工業株式会社 | ピロロ[2,3−c]ピリジン化合物、その製造方法および用途 |
| AU2005268767A1 (en) * | 2004-08-02 | 2006-02-09 | Altana Pharma Ag | 5-substituted 1H-pyrrolo[3,2-B]pyridines |
| DK1784402T3 (da) * | 2004-09-03 | 2011-11-14 | Yuhan Corp | Pyrrolo[3,2-c]pyridinderivater samt fremgangsmåder til deres fremstilling |
| DK1784404T3 (da) * | 2004-09-03 | 2012-02-13 | Yuhan Corp | Pyrrolo[2,3-c]pyridinderivater samt fremgangsmåder til deres fremstilling |
| ES2426920T3 (es) * | 2004-09-03 | 2013-10-25 | Yuhan Corporation | Derivados de pirrolo[3,2-B]piridina y procesos para su preparación |
| RU2375359C2 (ru) * | 2004-09-03 | 2009-12-10 | Юхан Корпорейшн | ПРОИЗВОДНЫЕ ПИРРОЛО[3, 2-c]ПИРИДИНА И СПОСОБЫ ИХ ПОЛУЧЕНИЯ |
| US7777040B2 (en) | 2005-05-03 | 2010-08-17 | Cgi Pharmaceuticals, Inc. | Certain substituted ureas, as modulators of kinase activity |
| EP1928237A4 (en) | 2005-09-02 | 2011-03-09 | Abbott Lab | NEW HETEROCYCLES BASED ON IMIDAZO |
| US20090156578A1 (en) * | 2005-12-05 | 2009-06-18 | PAULS Henry | 3-Heterocyclylacrylamide Compounds as Fab I Inhibitors and Antibacterial Agents |
| JP2009539840A (ja) * | 2006-06-06 | 2009-11-19 | シェーリング コーポレイション | プロテインキナーゼ阻害剤としてのイミダゾピラジン |
| EP2054422B1 (en) | 2006-07-20 | 2017-06-14 | Debiopharm International SA | Acrylamide derivatives as fab i inhibitors |
| WO2008098374A1 (en) * | 2007-02-16 | 2008-08-21 | Affinium Pharmaceuticals, Inc. | Salts, prodrugs and polymorphs of fab i inhibitors |
| JP5496915B2 (ja) | 2008-02-13 | 2014-05-21 | シージーアイ ファーマシューティカルズ,インコーポレーテッド | 6−アリール−イミダゾ[1,2−a]ピラジン誘導体、その製造方法、及びその使用方法 |
| EA020461B1 (ru) | 2008-12-08 | 2014-11-28 | Джилид Коннектикут, Инк. | ИМИДАЗОПИРАЗИНОВЫЕ ИНГИБИТОРЫ Syk |
| PE20120121A1 (es) | 2008-12-08 | 2012-02-20 | Gilead Connecticut Inc | Derivados de imidazopirazina como inhibidores de syk |
| US8450321B2 (en) | 2008-12-08 | 2013-05-28 | Gilead Connecticut, Inc. | 6-(1H-indazol-6-yl)-N-[4-(morpholin-4-yl)phenyl]imidazo-[1,2-A]pyrazin-8-amine, or a pharmaceutically acceptable salt thereof, as a SYK inhibitor |
| JP5938352B2 (ja) | 2010-03-11 | 2016-06-22 | ギリアード コネチカット, インコーポレイテッド | イミダゾピリジンsyk阻害剤 |
| EP2861608B8 (en) | 2012-06-19 | 2019-06-19 | Debiopharm International SA | Prodrug derivatives of (e)-n-methyl-n-((3-methylbenzofuran-2-yl)methyl)-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide |
| EA029281B1 (ru) | 2013-07-30 | 2018-03-30 | Джилид Коннектикут, Инк. | Полиморф ингибиторов syk |
| PL3027171T3 (pl) | 2013-07-30 | 2020-08-24 | Gilead Connecticut, Inc. | Formulacja inhibitorów syk |
| AU2014360537B2 (en) | 2013-12-04 | 2017-09-07 | Gilead Sciences, Inc. | Methods for treating cancers |
| GB201321738D0 (en) * | 2013-12-09 | 2014-01-22 | Ucb Pharma Sa | Therapeutic Agents |
| TWI662037B (zh) | 2013-12-23 | 2019-06-11 | 美商基利科學股份有限公司 | 脾酪胺酸激酶抑制劑 |
| US9290505B2 (en) | 2013-12-23 | 2016-03-22 | Gilead Sciences, Inc. | Substituted imidazo[1,2-a]pyrazines as Syk inhibitors |
| CN106687139A (zh) | 2014-07-14 | 2017-05-17 | 吉利德科学公司 | 用于治疗癌症的组合 |
| DK3419628T3 (da) | 2016-02-26 | 2021-01-11 | Debiopharm Int Sa | Medikament til behandling af diabetiske fodinfektioner |
| KR20220070056A (ko) | 2017-08-25 | 2022-05-27 | 길리애드 사이언시즈, 인코포레이티드 | Syk 억제제의 다형체 |
| ES2944535T3 (es) | 2019-02-14 | 2023-06-22 | Debiopharm Int Sa | Formulación de afabicina, método para preparar la misma |
| AU2020225455A1 (en) | 2019-02-22 | 2021-09-09 | Kronos Bio, Inc. | Solid forms of condensed pyrazines as Syk inhibitors |
| UA129222C2 (uk) | 2019-06-14 | 2025-02-12 | Дебіофарм Інтернешнл С.А. | Лікарський засіб і його застосування для лікування бактеріальних інфекцій, пов'язаних з біоплівкою |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4507294A (en) * | 1982-03-08 | 1985-03-26 | Schering Corp. | Imidazo[1,2-a]pyrazines |
| EP0068378B1 (en) * | 1981-06-26 | 1986-03-05 | Schering Corporation | Novel imidazo(1,2-a)pyridines and pyrazines, processes for their preparation and pharmaceutical compositions containing them |
| US4725601A (en) | 1985-06-04 | 1988-02-16 | Fujisawa Pharmaceutical Co., Ltd. | Certain imidazo[1,2-a]pyridines useful in the treatment of ulcers |
| PT97467A (pt) * | 1990-04-27 | 1992-01-31 | Byk Gulden Lomberg Chem Fab | Processo para preparacao de novas piridazinas e de composicoes farmaceuticas que as contem |
| US5041442A (en) * | 1990-07-31 | 1991-08-20 | Syntex (U.S.A.) Inc. | Pyrrolo(1,2-a)pyrazines as inhibitors of gastric acid secretion |
| WO1992006979A1 (de) * | 1990-10-15 | 1992-04-30 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Neue diazine |
| ATE179419T1 (de) * | 1991-10-25 | 1999-05-15 | Byk Gulden Lomberg Chem Fab | Pyrrolo-pyridazine mit magen- und darmschutzwirkungen |
| HU225920B1 (en) | 1994-01-19 | 2008-01-28 | Sankyo Co | Pyrrolo[2,3-d]pyridazine derivatives, process for their preparation and pharmaceutical compositions containing them |
| SE9602286D0 (sv) | 1996-06-10 | 1996-06-10 | Astra Ab | New compounds |
| SE9700661D0 (sv) | 1997-02-25 | 1997-02-25 | Astra Ab | New compounds |
| SE9704404D0 (sv) | 1997-11-28 | 1997-11-28 | Astra Ab | New compounds |
-
1997
- 1997-11-28 SE SE9704404A patent/SE9704404D0/xx unknown
-
1998
- 1998-11-16 TW TW087118942A patent/TW515798B/zh active
- 1998-11-16 AR ARP980105799A patent/AR016972A1/es unknown
- 1998-11-16 ZA ZA9810468A patent/ZA9810468B/xx unknown
- 1998-11-17 MY MYPI98005216A patent/MY121032A/en unknown
- 1998-11-18 EP EP98957270A patent/EP1042324B1/en not_active Expired - Lifetime
- 1998-11-18 ID IDW20000987A patent/ID24730A/id unknown
- 1998-11-18 AT AT98957270T patent/ATE233263T1/de not_active IP Right Cessation
- 1998-11-18 UA UA2000052801A patent/UA70932C2/uk unknown
- 1998-11-18 TR TR2000/01530T patent/TR200001530T2/xx unknown
- 1998-11-18 SK SK674-2000A patent/SK283904B6/sk unknown
- 1998-11-18 AU AU13565/99A patent/AU752187C/en not_active Ceased
- 1998-11-18 DK DK98957270T patent/DK1042324T3/da active
- 1998-11-18 JP JP2000523214A patent/JP2001525322A/ja active Pending
- 1998-11-18 PL PL98340920A patent/PL340920A1/xx not_active Application Discontinuation
- 1998-11-18 CN CNB98813344XA patent/CN1142933C/zh not_active Expired - Fee Related
- 1998-11-18 RU RU2000113729/04A patent/RU2241000C2/ru not_active IP Right Cessation
- 1998-11-18 EE EEP200000315A patent/EE04060B1/xx not_active IP Right Cessation
- 1998-11-18 DE DE69811735T patent/DE69811735T2/de not_active Expired - Fee Related
- 1998-11-18 KR KR1020007005804A patent/KR20010032559A/ko not_active Ceased
- 1998-11-18 US US09/194,823 patent/US6518270B1/en not_active Expired - Lifetime
- 1998-11-18 CA CA002311798A patent/CA2311798A1/en not_active Abandoned
- 1998-11-18 BR BR9814755-2A patent/BR9814755A/pt not_active Application Discontinuation
- 1998-11-18 HU HU0100601A patent/HUP0100601A3/hu unknown
- 1998-11-18 CZ CZ20001947A patent/CZ292349B6/cs not_active IP Right Cessation
- 1998-11-18 PT PT98957270T patent/PT1042324E/pt unknown
- 1998-11-18 WO PCT/SE1998/002091 patent/WO1999028322A1/en not_active Ceased
- 1998-11-18 ES ES98957270T patent/ES2191356T3/es not_active Expired - Lifetime
- 1998-11-18 NZ NZ504355A patent/NZ504355A/en unknown
- 1998-11-18 IL IL13614598A patent/IL136145A0/xx unknown
-
2000
- 2000-05-10 IS IS5486A patent/IS5486A/is unknown
- 2000-05-26 NO NO20002721A patent/NO315704B1/no unknown
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