IS5486A - Heterósýklísk efnasambönd til að hindra magasýruflæði, aðferðir við framleiðslu þeirra og lyfjablöndur er innihalda þau - Google Patents

Heterósýklísk efnasambönd til að hindra magasýruflæði, aðferðir við framleiðslu þeirra og lyfjablöndur er innihalda þau

Info

Publication number
IS5486A
IS5486A IS5486A IS5486A IS5486A IS 5486 A IS5486 A IS 5486A IS 5486 A IS5486 A IS 5486A IS 5486 A IS5486 A IS 5486A IS 5486 A IS5486 A IS 5486A
Authority
IS
Iceland
Prior art keywords
pharmaceutical compositions
compositions containing
production methods
heterocyclic compounds
gastric acid
Prior art date
Application number
IS5486A
Other languages
English (en)
Inventor
Amin Kosrat
Dahlström Mikael
Nordberg Peter
Starke Ingemar
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of IS5486A publication Critical patent/IS5486A/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
IS5486A 1997-11-28 2000-05-10 Heterósýklísk efnasambönd til að hindra magasýruflæði, aðferðir við framleiðslu þeirra og lyfjablöndur er innihalda þau IS5486A (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9704404A SE9704404D0 (sv) 1997-11-28 1997-11-28 New compounds
PCT/SE1998/002091 WO1999028322A1 (en) 1997-11-28 1998-11-18 Heterocyclic compounds for inhibition of gastric acid secretion, processes for their preparation and pharmaceutical compositions thereof

Publications (1)

Publication Number Publication Date
IS5486A true IS5486A (is) 2000-05-10

Family

ID=20409181

Family Applications (1)

Application Number Title Priority Date Filing Date
IS5486A IS5486A (is) 1997-11-28 2000-05-10 Heterósýklísk efnasambönd til að hindra magasýruflæði, aðferðir við framleiðslu þeirra og lyfjablöndur er innihalda þau

Country Status (32)

Country Link
US (1) US6518270B1 (is)
EP (1) EP1042324B1 (is)
JP (1) JP2001525322A (is)
KR (1) KR20010032559A (is)
CN (1) CN1142933C (is)
AR (1) AR016972A1 (is)
AT (1) ATE233263T1 (is)
AU (1) AU752187C (is)
BR (1) BR9814755A (is)
CA (1) CA2311798A1 (is)
CZ (1) CZ292349B6 (is)
DE (1) DE69811735T2 (is)
DK (1) DK1042324T3 (is)
EE (1) EE04060B1 (is)
ES (1) ES2191356T3 (is)
HU (1) HUP0100601A3 (is)
ID (1) ID24730A (is)
IL (1) IL136145A0 (is)
IS (1) IS5486A (is)
MY (1) MY121032A (is)
NO (1) NO315704B1 (is)
NZ (1) NZ504355A (is)
PL (1) PL340920A1 (is)
PT (1) PT1042324E (is)
RU (1) RU2241000C2 (is)
SE (1) SE9704404D0 (is)
SK (1) SK283904B6 (is)
TR (1) TR200001530T2 (is)
TW (1) TW515798B (is)
UA (1) UA70932C2 (is)
WO (1) WO1999028322A1 (is)
ZA (1) ZA9810468B (is)

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TW200418479A (en) * 2002-09-25 2004-10-01 Sankyo Co Pharmaceutical compositions for the treatment or prevention of visceral pains
AU2003266622A1 (en) * 2002-09-25 2004-04-19 Sankyo Company, Limited Medicinal composition for inhibiting increase in blood gastrin concentration
EP1575951B1 (en) 2002-12-06 2014-06-25 Debiopharm International SA Heterocyclic compounds, methods of making them and their use in therapy
US7160885B2 (en) 2003-02-10 2007-01-09 Cgi Pharmaceuticals, Inc. Certain 6, 8-(heteroaryl or aryl) disubstituted imidazo[1,2-a]pyrazines as modulators of Hsp90 complex activity
AR043002A1 (es) * 2003-02-18 2005-07-13 Altana Pharma Ag Imidazopirazinas 6-substituidos
WO2004082586A2 (en) * 2003-03-17 2004-09-30 Affinium Pharmaceuticals, Inc. Phamaceutical compositions comprising inhibitors of fab i and further antibiotics
US7405295B2 (en) 2003-06-04 2008-07-29 Cgi Pharmaceuticals, Inc. Certain imidazo[1,2-a]pyrazin-8-ylamines and method of inhibition of Bruton's tyrosine kinase by such compounds
WO2005005429A1 (en) 2003-06-30 2005-01-20 Cellular Genomics, Inc. Certain heterocyclic substituted imidazo[1,2-a]pyrazin-8-ylamines and methods of inhibition of bruton’s tyrosine kinase by such compounds
WO2005019220A2 (en) 2003-08-11 2005-03-03 Cellular Genomics Inc. Substituted imidazo[1,2-a]pyrazines as modulators of kinase activity
EP1974730A1 (en) 2003-11-03 2008-10-01 AstraZeneca AB Imidazo[1,2-a]pyridine derivatives for use in the treatment of sleep disturbance due to silent gastro-esophageal reflux
US8450307B2 (en) 2004-06-04 2013-05-28 Affinium Pharmaceuticals, Inc. Therapeutic agents, and methods of making and using the same
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WO2006013195A1 (en) * 2004-08-02 2006-02-09 Altana Pharma Ag 5-substituted 1h-pyrrolo[3,2-b]pyridines
WO2006025716A1 (en) 2004-09-03 2006-03-09 Yuhan Corporation Pyrrolo[2,3-c]pyridine derivatives and processes for the preparation thereof
DE602005020957D1 (de) * 2004-09-03 2010-06-10 Yuhan Corp Pyrroloä3,2-cüpyridinderivate und verfahren zu deren herstellung
ES2367312T3 (es) 2004-09-03 2011-11-02 Yuhan Corporation DERIVADOS DE PIRROLO [3,2-c] PIRIDINA Y PROCESOS PARA LA PREPARACIÓN DE LOS MISMOS.
JP4989478B2 (ja) * 2004-09-03 2012-08-01 ユーハン・コーポレイション ピロロ［３，２−ｂ］ピリジン誘導体及びその製造方法
WO2007024294A2 (en) 2005-05-03 2007-03-01 Cgi Pharmaceuticals, Inc. Certain substituted ureas, as modulators of kinase activity
US7709468B2 (en) 2005-09-02 2010-05-04 Abbott Laboratories Imidazo based heterocycles
CA2632476A1 (en) * 2005-12-05 2007-06-14 Affinium Pharmaceuticals, Inc. Heterocyclylacrylamide compounds as fabi inhibitors and antibacterial agents
MX2008015747A (es) 2006-06-06 2008-12-19 Schering Corp Imidazopirazinas como inhibidores de la proteina quinasa.
EP2687533B1 (en) 2006-07-20 2017-07-19 Debiopharm International SA Acrylamide derivatives as FAB I inhibitors
WO2008098374A1 (en) * 2007-02-16 2008-08-21 Affinium Pharmaceuticals, Inc. Salts, prodrugs and polymorphs of fab i inhibitors
EP2252617A1 (en) 2008-02-13 2010-11-24 CGI Pharmaceuticals, Inc. 6-aryl-imidaz0[l, 2-a]pyrazine derivatives, method of making, and method of use thereof
EA021293B1 (ru) 2008-12-08 2015-05-29 Джилид Коннектикут, Инк. ИМИДАЗОПИРАЗИНОВЫЕ ИНГИБИТОРЫ Syk, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, СОДЕРЖАЩАЯ ИМИДАЗОПИРАЗИНОВЫЕ ИНГИБИТОРЫ Syk, И СПОСОБЫ ИХ ПРИМЕНЕНИЯ
SG171991A1 (en) 2008-12-08 2011-07-28 Gilead Connecticut Inc Imidazopyrazine syk inhibitors
US8450321B2 (en) 2008-12-08 2013-05-28 Gilead Connecticut, Inc. 6-(1H-indazol-6-yl)-N-[4-(morpholin-4-yl)phenyl]imidazo-[1,2-A]pyrazin-8-amine, or a pharmaceutically acceptable salt thereof, as a SYK inhibitor
PT2545052E (pt) 2010-03-11 2015-02-18 Gilead Connecticut Inc Inibidores da syk à base de imidazopiridinas
KR101720885B1 (ko) 2012-06-19 2017-03-28 데비오팜 인터네셔날 에스 에이 (e)-n-메틸-n-((3-메틸벤조푸란-2-일)메틸)-3-(7-옥소-5,6,7,8-테트라히드로-1,8-나프티리딘-3-일)아크릴아미드의전구약물 유도체
MD4684B1 (ro) 2013-07-30 2020-03-31 Gilead Connecticut INc. Formulări pe bază de imidazopirazine în calitate de inhibitori SYK
ES2822285T3 (es) 2013-07-30 2021-04-30 Kronos Bio Inc Polimorfo de inhibidores de SYK
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TWI735853B (zh) 2013-12-23 2021-08-11 美商克洛諾斯生技有限公司 脾酪胺酸激酶抑制劑
US9290505B2 (en) 2013-12-23 2016-03-22 Gilead Sciences, Inc. Substituted imidazo[1,2-a]pyrazines as Syk inhibitors
AU2015290000B2 (en) 2014-07-14 2018-05-17 Gilead Sciences, Inc. Combinations for treating cancers
RS61312B1 (sr) 2016-02-26 2021-02-26 Debiopharm Int Sa Lek za lečenje infekcija dijabetskog stopala
US11384082B2 (en) 2017-08-25 2022-07-12 Kronos Bio, Inc. Hydrates of polymorphs of 6-(1H-indazol-6-YL)-N-(4-morpholinophenyl)-2,3-dihydroimidazo[1,2-A]pyrazin-8-amine bisemsylate as Syk inhibitors
MY203711A (en) 2019-02-14 2024-07-15 Debiopharm Int Sa Afabicin formulation, method for making the same and uses thereof
US11339168B2 (en) 2019-02-22 2022-05-24 Kronos Bio, Inc. Crystalline forms of 6-(6-aminopyrazin-2-yl)-N-(4-(4-(oxetan-3-yl)piperazin-1-yl)phenyl)imidazo[1,2-a]pyrazin-8-amine as Syk inhibitors
JP7418475B2 (ja) 2019-06-14 2024-01-19 デバイオファーム インターナショナル エス．エー． バイオフィルムが関与する細菌感染症を治療するための医薬及びその使用

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Also Published As

Publication number Publication date
WO1999028322A1 (en) 1999-06-10
CA2311798A1 (en) 1999-06-10
CN1142933C (zh) 2004-03-24
AR016972A1 (es) 2001-08-01
ZA9810468B (en) 1999-05-21
EP1042324B1 (en) 2003-02-26
NZ504355A (en) 2001-12-21
DE69811735D1 (de) 2003-04-03
US6518270B1 (en) 2003-02-11
MY121032A (en) 2005-12-30
NO315704B1 (no) 2003-10-13
HUP0100601A3 (en) 2002-10-28
ES2191356T3 (es) 2003-09-01
SK6742000A3 (en) 2001-03-12
AU752187B2 (en) 2002-09-12
AU752187C (en) 2003-09-18
BR9814755A (pt) 2000-10-03
ID24730A (id) 2000-08-03
AU1356599A (en) 1999-06-16
EE200000315A (et) 2001-10-15
NO20002721D0 (no) 2000-05-26
KR20010032559A (ko) 2001-04-25
SK283904B6 (sk) 2004-04-06
TR200001530T2 (tr) 2000-11-21
IL136145A0 (en) 2001-05-20
ATE233263T1 (de) 2003-03-15
HK1030216A1 (en) 2001-04-27
EP1042324A1 (en) 2000-10-11
UA70932C2 (uk) 2004-11-15
EE04060B1 (et) 2003-06-16
HUP0100601A2 (hu) 2001-09-28
DK1042324T3 (da) 2003-05-05
TW515798B (en) 2003-01-01
CZ292349B6 (cs) 2003-09-17
CZ20001947A3 (cs) 2000-11-15
PT1042324E (pt) 2003-06-30
RU2241000C2 (ru) 2004-11-27
SE9704404D0 (sv) 1997-11-28
DE69811735T2 (de) 2003-12-18
CN1284078A (zh) 2001-02-14
JP2001525322A (ja) 2001-12-11
PL340920A1 (en) 2001-03-12
NO20002721L (no) 2000-07-28

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